Green Card Research Manager Jobs
Research Manager roles at U.S. universities, pharma companies, and federal contractors regularly qualify for EB-2 or EB-3 green card sponsorship through PERM labor certification. Employers document that no qualified U.S. worker is available before filing your I-140 petition, making your advanced degree and research leadership credentials central to a strong sponsorship case.
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As a top cancer care provider in Florida, Orlando Health Cancer Institute is a comprehensive, multidisciplinary cancer program consisting of six treatment sites and more than 10 practice locations that serve the region’s adult oncology needs. Specializing in more than 200 types of cancer, an expert team of medical professionals provides personalized care with the most state-of-the-art technologies, such as advanced radiation and proton therapies, and bone marrow transplant and cellular therapy. Through a robust research program, the institute also supports physician involvement in numerous research studies and clinical trials that give patients access to innovative diagnosis, treatment and symptom management options. In addition to being accredited by the Commission on Cancer, a program of the American College of Surgeons, Orlando Health Cancer Institute has earned accreditations and certifications in several areas — including medical oncology and hematology/oncology, radiation oncology, cellular therapy, rectal cancer, and breast care — from the respective accrediting organizations, and recently was named in the 2023 Becker's Hospital Review “60 Hospitals and Health Systems with Great Oncology Programs” list.
Orlando Health Cancer Institute is part of the Orlando Health system of care, which includes 24 award-winning hospitals and ERs, 9 specialty institutes, 14 urgent care centers, 100+ primary care practices and more than 60 outpatient facilities that span Florida’s east to west coasts and beyond. Collectively, we honor our 100-year legacy by providing care for more than 142,000 inpatient and 3.9 million outpatient visits each year.
Orlando Health is committed to providing you with benefits that go beyond the expected, with career-growing FREE education programs and well-being services to support you and your family through every stage of life. We begin your benefits on day one and offer flexibility wherever possible so that you can be present for your passions. “Orlando Health Is Your Best Place to Work” is not just something we say, it’s our promise to you.
A Brief Overview
The Clinical Research Regulatory Coordinator II independently prepares and submits regulatory documentation for routine-to-moderately complex clinical research studies to local and central IRBs and other regulatory authorities. Maintains regulatory compliance throughout the study lifecycle and serves as a regulatory resource for study teams. Independent contributor responsible for routine-to-moderately complex regulatory portfolio. Uses judgment to resolve routine issues and escalates complex or high-risk matters. This role represents an independent contributor level within a specialized clinical research regulatory career pathway, with increasing responsibility for regulatory decision-making and study complexity. These roles support specialized clinical research regulatory functions requiring independent judgment, technical proficiency, and the ability to manage increasing levels of study complexity across the clinical research lifecycle.
Responsibilities:
- Independently prepare and submit local and central IRB materials for new studies, amendments, continuing reviews, safety events, protocol deviations, consent revisions, and study closures
- Maintain complete, inspection-ready regulatory binders and electronic records for assigned studies
- Serve as liaison among investigators, sponsors, consortium partners, funding entities, IRBs, CORO, and ancillary review committees
- Respond to IRB, sponsor, and regulatory queries; identify issues requiring escalation and recommend compliant resolution pathways
- Prepare assigned studies for monitoring visits and audits; assist with corrective actions and documentation follow-up
- Guide less experienced staff on routine submissions, binder standards, tracking requirements, and study documentation expectations
- Apply regulatory requirements for industry-sponsored, cooperative group/national, and investigator-initiated trials
- Participate in departmental quality assurance, process improvement, and standard work initiatives
- Performs other duties as assigned
- Attends team, staff, departmental, sponsor, and/or cross-functional meetings as required
- Maintains proficiency with clinical research systems, IRB platforms, CTMS/e-regulatory systems, document management tools, and department specific software
- Maintains reasonably regular, punctual attendance consistent with Orlando Health policies, the ADA, FMLA and other federal, state and local standards
- Maintains compliance with all Orlando Health policies and procedures
Qualifications
Bachelor’s degree in healthcare, life sciences, regulatory, or related field required.
Associate’s degree and two (2) years of directly related work experience (in addition to the requirements listed in the Experience section) may substitute for the bachelor's degree requirement.
High school diploma or equivalent and four (4) years of directly related work experience (in addition to the requirements listed in the Experience section) may substitute for the bachelor's degree requirement.
Additional specialty training in quality, project management, oncology research, or regulatory affairs preferred.
Two (2) years of direct clinical research regulatory experience required.
Experience with local and central IRB submissions, regulatory documentation, and study lifecycle management preferred.
Experience serving as a regulatory resource to study teams and independently managing routine-to-moderately complex regulatory submissions preferred.
Must be eligible for SOCRA CCRP, ACRP CCRC/ACRP-CP, or PRIM&R CIP; active certification is preferred.
Position Summary:
As a top cancer care provider in Florida, Orlando Health Cancer Institute is a comprehensive, multidisciplinary cancer program consisting of six treatment sites and more than 10 practice locations that serve the region’s adult oncology needs. Specializing in more than 200 types of cancer, an expert team of medical professionals provides personalized care with the most state-of-the-art technologies, such as advanced radiation and proton therapies, and bone marrow transplant and cellular therapy. Through a robust research program, the institute also supports physician involvement in numerous research studies and clinical trials that give patients access to innovative diagnosis, treatment and symptom management options. In addition to being accredited by the Commission on Cancer, a program of the American College of Surgeons, Orlando Health Cancer Institute has earned accreditations and certifications in several areas — including medical oncology and hematology/oncology, radiation oncology, cellular therapy, rectal cancer, and breast care — from the respective accrediting organizations, and recently was named in the 2023 Becker's Hospital Review “60 Hospitals and Health Systems with Great Oncology Programs” list.
Orlando Health Cancer Institute is part of the Orlando Health system of care, which includes 24 award-winning hospitals and ERs, 9 specialty institutes, 14 urgent care centers, 100+ primary care practices and more than 60 outpatient facilities that span Florida’s east to west coasts and beyond. Collectively, we honor our 100-year legacy by providing care for more than 142,000 inpatient and 3.9 million outpatient visits each year.
Orlando Health is committed to providing you with benefits that go beyond the expected, with career-growing FREE education programs and well-being services to support you and your family through every stage of life. We begin your benefits on day one and offer flexibility wherever possible so that you can be present for your passions. “Orlando Health Is Your Best Place to Work” is not just something we say, it’s our promise to you.
A Brief Overview
The Clinical Research Regulatory Coordinator II independently prepares and submits regulatory documentation for routine-to-moderately complex clinical research studies to local and central IRBs and other regulatory authorities. Maintains regulatory compliance throughout the study lifecycle and serves as a regulatory resource for study teams. Independent contributor responsible for routine-to-moderately complex regulatory portfolio. Uses judgment to resolve routine issues and escalates complex or high-risk matters. This role represents an independent contributor level within a specialized clinical research regulatory career pathway, with increasing responsibility for regulatory decision-making and study complexity. These roles support specialized clinical research regulatory functions requiring independent judgment, technical proficiency, and the ability to manage increasing levels of study complexity across the clinical research lifecycle.
Responsibilities:
- Independently prepare and submit local and central IRB materials for new studies, amendments, continuing reviews, safety events, protocol deviations, consent revisions, and study closures
- Maintain complete, inspection-ready regulatory binders and electronic records for assigned studies
- Serve as liaison among investigators, sponsors, consortium partners, funding entities, IRBs, CORO, and ancillary review committees
- Respond to IRB, sponsor, and regulatory queries; identify issues requiring escalation and recommend compliant resolution pathways
- Prepare assigned studies for monitoring visits and audits; assist with corrective actions and documentation follow-up
- Guide less experienced staff on routine submissions, binder standards, tracking requirements, and study documentation expectations
- Apply regulatory requirements for industry-sponsored, cooperative group/national, and investigator-initiated trials
- Participate in departmental quality assurance, process improvement, and standard work initiatives
- Performs other duties as assigned
- Attends team, staff, departmental, sponsor, and/or cross-functional meetings as required
- Maintains proficiency with clinical research systems, IRB platforms, CTMS/e-regulatory systems, document management tools, and department specific software
- Maintains reasonably regular, punctual attendance consistent with Orlando Health policies, the ADA, FMLA and other federal, state and local standards
- Maintains compliance with all Orlando Health policies and procedures
Qualifications
Bachelor’s degree in healthcare, life sciences, regulatory, or related field required.
Associate’s degree and two (2) years of directly related work experience (in addition to the requirements listed in the Experience section) may substitute for the bachelor's degree requirement.
High school diploma or equivalent and four (4) years of directly related work experience (in addition to the requirements listed in the Experience section) may substitute for the bachelor's degree requirement.
Additional specialty training in quality, project management, oncology research, or regulatory affairs preferred.
Two (2) years of direct clinical research regulatory experience required.
Experience with local and central IRB submissions, regulatory documentation, and study lifecycle management preferred.
Experience serving as a regulatory resource to study teams and independently managing routine-to-moderately complex regulatory submissions preferred.
Must be eligible for SOCRA CCRP, ACRP CCRC/ACRP-CP, or PRIM&R CIP; active certification is preferred.
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Get Access To All JobsTips for Finding Green Card Sponsorship as a Research Manager
Frame your research credentials for PERM
PERM labor certification requires your employer to define the minimum job requirements. If your role genuinely needs a master's degree or specialized research methodology expertise, document that clearly before recruitment begins so the job description supports an EB-2 filing.
Target employers with federal research contracts
Universities, national laboratories, and pharmaceutical companies with NIH or NSF funding sponsor green cards far more consistently than private-sector firms. Federal contract requirements often make PERM sponsorship a standard part of hiring for senior research positions.
Use Migrate Mate to filter sponsoring employers
Search Migrate Mate to identify Research Manager roles at employers with active green card filing history. Filtering by sponsorship status upfront saves months of negotiating with employers who have never run a PERM case.
Negotiate sponsorship timing before accepting an offer
Ask your prospective employer when they will initiate PERM after your start date. Many research institutions have a one-year minimum tenure requirement before filing. Confirming this timeline in your offer letter protects you if leadership or HR priorities shift later.
Verify the prevailing wage before PERM recruitment starts
Your employer must submit a prevailing wage determination to DOL before advertising the position. Use the OFLC Wage Search to check the expected wage level for your SOC code and location so you can flag a mismatch before the process locks in.
Understand how EB-2 NIW applies to research leadership
If your research has national importance, USCIS allows a National Interest Waiver (NIW) under EB-2, bypassing PERM entirely. This self-petition path suits Research Managers with published work, grant funding, or policy impact that extends beyond their direct employer.
Green Card Research Manager: Frequently Asked Questions
Does a Research Manager role typically qualify for EB-2 or EB-3 sponsorship?
Most Research Manager positions qualify for EB-2 because the role normally requires a master's degree or its equivalent in a specific research discipline. If your employer defines the minimum requirement as a bachelor's degree with experience, the role may fall under EB-3 instead. The PERM job description your employer files determines which category applies, so that wording matters before recruitment begins.
How does green card sponsorship differ from H-1B for a Research Manager?
H-1B visa is a temporary work visa subject to an annual lottery, while EB-2 and EB-3 green card sponsorship through PERM leads to permanent residency with no cap concerns at the petition level. The PERM process typically takes one to three years from labor certification through I-140 approval, but once your priority date is current, you can adjust status without leaving the U.S. and without re-entering a lottery.
Where can I find Research Manager jobs with green card sponsorship?
Use Migrate Mate to search Research Manager roles filtered by employers with documented green card filing history. Most general job boards don't surface sponsorship status, so you can spend months applying to roles where the employer has never initiated a PERM case. Filtering by sponsorship upfront focuses your search on employers already familiar with the EB-2 and EB-3 process.
Can a Research Manager self-petition for a green card without employer sponsorship?
Yes, under the EB-2 National Interest Waiver (NIW), a Research Manager can self-petition if their work has substantial merit and national importance. USCIS evaluates your research record, citations, grants, and policy impact. This path bypasses PERM labor certification entirely, which is valuable if your employer is unwilling to sponsor or if you want to change employers without restarting the process.
What happens to my green card case if I change employers during the PERM process?
If you change employers before your I-140 is approved, your PERM labor certification is generally not transferable and your employer will need to start over with a new filing. Once your I-140 is approved and you have accumulated 180 days of I-485 pendency, portability rules under AC21 let you move to a same or similar role without restarting from the beginning.