Research Manager Green Card Jobs
Research Manager roles at U.S. universities, pharma companies, and federal contractors regularly qualify for EB-2 or EB-3 green card sponsorship through PERM labor certification. Employers document that no qualified U.S. worker is available before filing your I-140 petition, making your advanced degree and research leadership credentials central to a strong sponsorship case.
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Job Ref:
JR-3916
Location:
450 Brookline Ave, BOSTON, MA 02215
Category:
Clinical Research
Employment Type:
Full time
Work Location:
Hybrid: 2-3 days onsite/week
Salary/Pay Rate:
$70,000.00 - $85,300.00 per year
Overview
This Assistant Clinical Research Manager (ACRM) position will work within the Breast Oncology clinical research program and assist in the management of the research team in the overall conduct of clinical trials using Good Clinical Practice under the auspices of the Principal Investigator. These positions, in collaboration with the program’s Clinical Research Managers, physicians, and research nursing staff, are responsible for assisting with the design, implementation, and evaluation of their program’s clinical research activities, related regulatory oversight, and will provide day-to-day supervision of their program’s clinical research staff as needed. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life-changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Clinical Trials Operations
- Assistant Clinical Research Managers (ACRM) will be responsible for assisting the Clinical Research Manager with the oversight of their disease group’s clinical trial portfolio and all related regulatory and compliance requirements.
- The ACRM will assist the CRM with all aspects of study start-up, active, and close-out activities for the group’s portfolio. They will be responsible for the required tracking of all protocol development, submission, review, and approval milestones.
- The ACRM will assist with the oversight of subject enrollment, protocol treatment, and follow-up care processes for protocol patients.
- Assist with the oversight of registration of protocol patients, study group registrar, and pharmaceutical company as outlined in protocol.
Regulatory & Compliance
- Assists in the responsibility for essential document compliance for the entire portfolio. Implements systems to monitor and ensure regulatory document collection and maintenance compliance.
- Assists in the responsibilities for all clinical trial reporting requirements; safety event, annual approval, deviations, etc. May implement systems to monitor portfolio compliance.
- Assists the study team to maintain an “audit ready” research environment.
Data Management & Clinical Trial Monitoring
- Assists CRM with responsibility for data management and compliance for the entire portfolio. Maintains schedules and procedures necessary for timely and complete data collection.
- Regularly reports data compliance status to key stakeholders; i.e. DFCI PI, study Sponsor, DFCI CTO. Helps to implement corrective action to maintain data compliance when necessary.
- Submits required “progress/tracking” reports to key stakeholders, when applicable.
Staff Training & Development
- Will assist the CRM with the recruitment and oversight of coordinator staff as well as ensure that staff have completed mandatory training in a timely manner.
- Will help implement program-specific onboarding and orientation process and may participate in annual performance evaluations and competency assessments of research staff as needed.
KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:
- Must be able to perform day-to-day responsibilities independently with minimal supervision from managers.
- Has the ability to identify regulatory scenarios that require consultation.
- Has a good understanding of clinical trials start-up, active and close-out phases.
- Has a good understanding of clinical research, local policy, and federal regulation.
- Knowledge of cancer as a disease process, cancer treatment modalities, and the clinical trial process.
- In addition, has experience in protocol development, data compilation, and analysis.
- The ACRM will have a good understanding of the various tracking systems used to ensure timely data management by the clinical research staff.
- They will also understand Federal and State regulations as they relate to research. Strong interpersonal, organizational, and communication skills are required.
- Must have computer skills including the use of Microsoft Office.
MINIMUM JOB QUALIFICATIONS:
- Bachelor’s Degree required.
- Minimum of 3 plus years of related experience preferred.
- Must have the ability to function independently, think critically, and with good professional judgment.
License/Certification/Registration:
N/A
SUPERVISORY RESPONSIBILITIES:
No direct report
- Will provide day-to-day supervision for study management staff, including clinical research coordinators, students, volunteers, and other research assistants as needed.
PATIENT CONTACT:
May have contact with patients of all ages and populations.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEO Poster
Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills, and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$70,000.00 - $85,300.00

Job Ref:
JR-3916
Location:
450 Brookline Ave, BOSTON, MA 02215
Category:
Clinical Research
Employment Type:
Full time
Work Location:
Hybrid: 2-3 days onsite/week
Salary/Pay Rate:
$70,000.00 - $85,300.00 per year
Overview
This Assistant Clinical Research Manager (ACRM) position will work within the Breast Oncology clinical research program and assist in the management of the research team in the overall conduct of clinical trials using Good Clinical Practice under the auspices of the Principal Investigator. These positions, in collaboration with the program’s Clinical Research Managers, physicians, and research nursing staff, are responsible for assisting with the design, implementation, and evaluation of their program’s clinical research activities, related regulatory oversight, and will provide day-to-day supervision of their program’s clinical research staff as needed. Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life-changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS, and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.
Clinical Trials Operations
- Assistant Clinical Research Managers (ACRM) will be responsible for assisting the Clinical Research Manager with the oversight of their disease group’s clinical trial portfolio and all related regulatory and compliance requirements.
- The ACRM will assist the CRM with all aspects of study start-up, active, and close-out activities for the group’s portfolio. They will be responsible for the required tracking of all protocol development, submission, review, and approval milestones.
- The ACRM will assist with the oversight of subject enrollment, protocol treatment, and follow-up care processes for protocol patients.
- Assist with the oversight of registration of protocol patients, study group registrar, and pharmaceutical company as outlined in protocol.
Regulatory & Compliance
- Assists in the responsibility for essential document compliance for the entire portfolio. Implements systems to monitor and ensure regulatory document collection and maintenance compliance.
- Assists in the responsibilities for all clinical trial reporting requirements; safety event, annual approval, deviations, etc. May implement systems to monitor portfolio compliance.
- Assists the study team to maintain an “audit ready” research environment.
Data Management & Clinical Trial Monitoring
- Assists CRM with responsibility for data management and compliance for the entire portfolio. Maintains schedules and procedures necessary for timely and complete data collection.
- Regularly reports data compliance status to key stakeholders; i.e. DFCI PI, study Sponsor, DFCI CTO. Helps to implement corrective action to maintain data compliance when necessary.
- Submits required “progress/tracking” reports to key stakeholders, when applicable.
Staff Training & Development
- Will assist the CRM with the recruitment and oversight of coordinator staff as well as ensure that staff have completed mandatory training in a timely manner.
- Will help implement program-specific onboarding and orientation process and may participate in annual performance evaluations and competency assessments of research staff as needed.
KNOWLEDGE, SKILLS, AND ABILITIES REQUIRED:
- Must be able to perform day-to-day responsibilities independently with minimal supervision from managers.
- Has the ability to identify regulatory scenarios that require consultation.
- Has a good understanding of clinical trials start-up, active and close-out phases.
- Has a good understanding of clinical research, local policy, and federal regulation.
- Knowledge of cancer as a disease process, cancer treatment modalities, and the clinical trial process.
- In addition, has experience in protocol development, data compilation, and analysis.
- The ACRM will have a good understanding of the various tracking systems used to ensure timely data management by the clinical research staff.
- They will also understand Federal and State regulations as they relate to research. Strong interpersonal, organizational, and communication skills are required.
- Must have computer skills including the use of Microsoft Office.
MINIMUM JOB QUALIFICATIONS:
- Bachelor’s Degree required.
- Minimum of 3 plus years of related experience preferred.
- Must have the ability to function independently, think critically, and with good professional judgment.
License/Certification/Registration:
N/A
SUPERVISORY RESPONSIBILITIES:
No direct report
- Will provide day-to-day supervision for study management staff, including clinical research coordinators, students, volunteers, and other research assistants as needed.
PATIENT CONTACT:
May have contact with patients of all ages and populations.
At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are committed to having faculty and staff who offer multifaceted experiences. Cancer knows no boundaries and when it comes to hiring the most dedicated and compassionate professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.
Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.
EEO Poster
Pay Transparency Statement
The hiring range is based on market pay structures, with individual salaries determined by factors such as business needs, market conditions, internal equity, and based on the candidate’s relevant experience, skills, and qualifications.
For union positions, the pay range is determined by the Collective Bargaining Agreement (CBA).
$70,000.00 - $85,300.00
See all 742+ Research Manager jobs
Sign up for free to unlock all listings, filter by visa type, and get alerts for new Research Manager roles.
Get Access To All JobsTips for Finding Green Card Sponsorship as a Research Manager
Frame your research credentials for PERM
PERM labor certification requires your employer to define the minimum job requirements. If your role genuinely needs a master's degree or specialized research methodology expertise, document that clearly before recruitment begins so the job description supports an EB-2 filing.
Target employers with federal research contracts
Universities, national laboratories, and pharmaceutical companies with NIH or NSF funding sponsor green cards far more consistently than private-sector firms. Federal contract requirements often make PERM sponsorship a standard part of hiring for senior research positions.
Use Migrate Mate to filter sponsoring employers
Search Migrate Mate to identify Research Manager roles at employers with active green card filing history. Filtering by sponsorship status upfront saves months of negotiating with employers who have never run a PERM case.
Negotiate sponsorship timing before accepting an offer
Ask your prospective employer when they will initiate PERM after your start date. Many research institutions have a one-year minimum tenure requirement before filing. Confirming this timeline in your offer letter protects you if leadership or HR priorities shift later.
Verify the prevailing wage before PERM recruitment starts
Your employer must submit a prevailing wage determination to DOL before advertising the position. Use the OFLC Wage Search to check the expected wage level for your SOC code and location so you can flag a mismatch before the process locks in.
Understand how EB-2 NIW applies to research leadership
If your research has national importance, USCIS allows a National Interest Waiver (NIW) under EB-2, bypassing PERM entirely. This self-petition path suits Research Managers with published work, grant funding, or policy impact that extends beyond their direct employer.
Research Manager jobs are hiring across the US. Find yours.
Find Research Manager JobsResearch Manager Green Card Sponsorship: Frequently Asked Questions
Does a Research Manager role typically qualify for EB-2 or EB-3 sponsorship?
Most Research Manager positions qualify for EB-2 because the role normally requires a master's degree or its equivalent in a specific research discipline. If your employer defines the minimum requirement as a bachelor's degree with experience, the role may fall under EB-3 instead. The PERM job description your employer files determines which category applies, so that wording matters before recruitment begins.
How does green card sponsorship differ from H-1B for a Research Manager?
H-1B is a temporary work visa subject to an annual lottery, while EB-2 and EB-3 green card sponsorship through PERM leads to permanent residency with no cap concerns at the petition level. The PERM process typically takes one to three years from labor certification through I-140 approval, but once your priority date is current, you can adjust status without leaving the U.S. and without re-entering a lottery.
Where can I find Research Manager jobs with green card sponsorship?
Use Migrate Mate to search Research Manager roles filtered by employers with documented green card filing history. Most general job boards don't surface sponsorship status, so you can spend months applying to roles where the employer has never initiated a PERM case. Filtering by sponsorship upfront focuses your search on employers already familiar with the EB-2 and EB-3 process.
Can a Research Manager self-petition for a green card without employer sponsorship?
Yes, under the EB-2 National Interest Waiver (NIW), a Research Manager can self-petition if their work has substantial merit and national importance. USCIS evaluates your research record, citations, grants, and policy impact. This path bypasses PERM labor certification entirely, which is valuable if your employer is unwilling to sponsor or if you want to change employers without restarting the process.
What happens to my green card case if I change employers during the PERM process?
If you change employers before your I-140 is approved, your PERM labor certification is generally not transferable and your employer will need to start over with a new filing. Once your I-140 is approved and you have accumulated 180 days of I-485 pendency, portability rules under AC21 let you move to a same or similar role without restarting from the beginning.
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