Green Card Toxicologist Jobs
Toxicologist roles in government labs, pharmaceutical companies, and environmental consultancies regularly qualify for EB-2 and EB-3 green card sponsorship through the PERM labor certification process. Employers document the role's degree requirements and prevailing wage obligations before filing an I-140 petition, putting you on a path to permanent residency rather than repeated visa renewals.
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Get Access To All JobsINTRODUCTION
As a Regulatory/Project Toxicologist within our Department of Pharmacology and Toxicology, you will spearhead the nonclinical safety strategy for Roche innovative genetic medicine portfolio. In this role, you will champion the safety evaluation of cutting-edge gene therapies—focusing on ocular- and CNS-directed programs—from early discovery through late-stage clinical development. You will collaborate with world-class multidisciplinary scientists, driving decisions that safely accelerate groundbreaking medicines to patients.
ROLE AND RESPONSIBILITIES
- Serve as the nonclinical safety lead and primary toxicology representative on cross-functional drug development project teams across discovery, pre-clinical, and clinical stages.
- Formulate, design, and direct integrated nonclinical safety and toxicology strategies (GLP and non-GLP) to support program progression and key regulatory milestones.
- Lead proactive safety risk identification and design investigative mechanistic studies to evaluate and mitigate treatment-related toxicities.
- Partner cross-functionally with Research Leads, Clinical, Regulatory, CMC, and external CROs to coordinate study execution, review protocols, and interpret complex safety data.
- Author and review comprehensive nonclinical safety documentation, high-level regulatory filings (e.g., INDs, CTAs, PIPs, BLAs, GMO applications), and clinical documents (Investigator Brochures, ICFs).
- Communicate scientific findings and safety risk assessments clearly to internal governance committees and represent the organization in meetings with global health authorities.
BASIC QUALIFICATIONS
- You hold a Ph.D. in Toxicology, Pharmacology, or a closely related scientific discipline.
- You bring a minimum of 2–3 years of relevant toxicology experience within the biopharmaceutical, biotechnology, or contract research (CRO) industry.
- You possess demonstrated experience in designing, executing, and interpreting robust nonclinical safety studies (GLP and non-GLP) that drive scientific and portfolio decisions.
- You demonstrate a working understanding of drug development processes and the role of nonclinical safety in guiding regulatory and early clinical strategies.
- You are an exceptional communicator and collaborator, recognized for critical data interpretation, complex scientific problem-solving, and cross-functional leadership.
PREFERRED QUALIFICATIONS
- Direct experience with genetic medicines, viral vectors (particularly AAVs), gene editing platforms, or novel RNA/oligonucleotide modalities.
- Prior experience with ocular- or central nervous system (CNS)-targeted drug delivery or therapeutic development.
- Demonstrated track record of authoring nonclinical regulatory modules for global health authority dossiers (IND/CTA) and participating in health authority interactions.
- Proven ability to manage multiple complex safety programs simultaneously while driving collaborative relationships with CRO partners and academic collaborators.
COMPENSATION
- The expected salary range for this position based on the primary location of Philadelphia is $104,900 to $194,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
BENEFITS
Relocation benefits are available for this job posting.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
INTRODUCTION
As a Regulatory/Project Toxicologist within our Department of Pharmacology and Toxicology, you will spearhead the nonclinical safety strategy for Roche innovative genetic medicine portfolio. In this role, you will champion the safety evaluation of cutting-edge gene therapies—focusing on ocular- and CNS-directed programs—from early discovery through late-stage clinical development. You will collaborate with world-class multidisciplinary scientists, driving decisions that safely accelerate groundbreaking medicines to patients.
ROLE AND RESPONSIBILITIES
- Serve as the nonclinical safety lead and primary toxicology representative on cross-functional drug development project teams across discovery, pre-clinical, and clinical stages.
- Formulate, design, and direct integrated nonclinical safety and toxicology strategies (GLP and non-GLP) to support program progression and key regulatory milestones.
- Lead proactive safety risk identification and design investigative mechanistic studies to evaluate and mitigate treatment-related toxicities.
- Partner cross-functionally with Research Leads, Clinical, Regulatory, CMC, and external CROs to coordinate study execution, review protocols, and interpret complex safety data.
- Author and review comprehensive nonclinical safety documentation, high-level regulatory filings (e.g., INDs, CTAs, PIPs, BLAs, GMO applications), and clinical documents (Investigator Brochures, ICFs).
- Communicate scientific findings and safety risk assessments clearly to internal governance committees and represent the organization in meetings with global health authorities.
BASIC QUALIFICATIONS
- You hold a Ph.D. in Toxicology, Pharmacology, or a closely related scientific discipline.
- You bring a minimum of 2–3 years of relevant toxicology experience within the biopharmaceutical, biotechnology, or contract research (CRO) industry.
- You possess demonstrated experience in designing, executing, and interpreting robust nonclinical safety studies (GLP and non-GLP) that drive scientific and portfolio decisions.
- You demonstrate a working understanding of drug development processes and the role of nonclinical safety in guiding regulatory and early clinical strategies.
- You are an exceptional communicator and collaborator, recognized for critical data interpretation, complex scientific problem-solving, and cross-functional leadership.
PREFERRED QUALIFICATIONS
- Direct experience with genetic medicines, viral vectors (particularly AAVs), gene editing platforms, or novel RNA/oligonucleotide modalities.
- Prior experience with ocular- or central nervous system (CNS)-targeted drug delivery or therapeutic development.
- Demonstrated track record of authoring nonclinical regulatory modules for global health authority dossiers (IND/CTA) and participating in health authority interactions.
- Proven ability to manage multiple complex safety programs simultaneously while driving collaborative relationships with CRO partners and academic collaborators.
COMPENSATION
- The expected salary range for this position based on the primary location of Philadelphia is $104,900 to $194,900. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.
BENEFITS
Relocation benefits are available for this job posting.
Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.
If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.
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Get Access To All JobsTips for Finding Green Card Sponsorship in Toxicologist
Document your toxicology credentials before applying
PERM requires your degree to align precisely with the role's stated requirements. A master's or Ph.D. in toxicology, pharmacology, or a closely related life science strengthens both EB-2 eligibility and the employer's labor certification filing.
Target employers with established PERM filing histories
Pharmaceutical manufacturers, contract research organizations, and federal agencies like the EPA and FDA routinely sponsor toxicologists. Search DOL PERM disclosure data by SOC code 19-1021 to identify employers who have filed recently for this occupation.
Use Migrate Mate to find sponsoring toxicologist roles
Filtering by green card sponsorship history saves you from applying to employers who have never filed a PERM petition. Migrate Mate surfaces toxicologist postings tied to employers with documented EB-2 and EB-3 filing activity.
Verify the prevailing wage before negotiating your offer
PERM locks your employer into paying at least the DOL prevailing wage for your work location and experience level. Use the OFLC Wage Search to check wage levels for toxicologist roles in your target metro area before salary discussions begin.
Clarify EB-2 versus EB-3 classification with your employer early
Roles requiring a master's degree or a bachelor's plus five years of progressive experience may qualify for EB-2, shortening wait times for many nationalities. Confirm which category the employer intends to file under before the PERM advertisement process starts.
Understand that PERM recruitment rules affect your offer timing
DOL requires employers to complete a mandatory recruitment period, including job postings and internal notices, before filing PERM. This process typically takes several months, so factor that window into your start-date and visa-status planning.
Green Card Toxicologist: Frequently Asked Questions
Do toxicologist roles typically qualify for EB-2 or EB-3 green card sponsorship?
Toxicologist positions most commonly qualify for EB-2 when the employer requires a master's degree or equivalent, or EB-3 when the role calls for a bachelor's degree in a relevant science. Because most toxicology jobs at pharmaceutical companies, contract labs, and regulatory agencies specify advanced degree requirements, EB-2 is the more frequent classification, though EB-3 remains available for roles where a bachelor's suffices.
How does the PERM green card process differ from H-1B sponsorship for a toxicologist?
H-1B visa is a temporary status with a three-year initial period and a competitive annual lottery at the 85,000-cap level. PERM-based green card sponsorship has no annual cap at the EB-3 tier for most countries and leads to permanent residency rather than a renewable temporary status. The tradeoff is timeline: PERM labor certification plus I-140 adjudication typically takes one to two years before you can file for adjustment of status, compared to an H-1B that can activate within months.
What documentation should I prepare to support a toxicologist PERM filing?
You'll need official transcripts confirming your degree in toxicology, pharmacology, biochemistry, or a closely related field, along with any professional certifications such as DABT (Diplomate of the American Board of Toxicology). Foreign transcripts often require a credential evaluation to confirm equivalency to a U.S. degree. Your employer's PERM attorney will also need a detailed description of your duties aligned to the position's listed requirements.
Which industries most actively sponsor toxicologists for green cards?
Pharmaceutical and biotechnology companies, contract research organizations, chemical manufacturers, and federal regulatory agencies consistently file PERM petitions for toxicologists. Environmental consulting firms that conduct risk assessments for EPA compliance also sponsor regularly. Searching DOL PERM disclosure data by the relevant SOC code lets you identify specific employers who have filed for this occupation in your target location.
How can I find toxicologist jobs where the employer is already willing to sponsor a green card?
Most job postings don't state green card sponsorship intent upfront, so cross-referencing employer PERM filing history is the practical approach. Migrate Mate filters toxicologist job listings by employers with documented EB-2 and EB-3 sponsorship activity, so you're applying to companies that have already demonstrated willingness to go through the PERM process rather than hoping to persuade an employer during negotiations.