Information Systems Manager Jobs

Information Systems Manager jobs are open across healthcare, finance, government, and technology, at levels from team lead to senior director, with specializations in IT infrastructure, enterprise systems, and cybersecurity program management. See the openings below and apply to the ones that match your experience.

Find Jobs

Overview

Open roles73
Top stateTexas
Top employerHPC Industrial
Top cityDallas, TX
Work type57% On-site
Top industryHealthcare

Showing 5 of 73+ Information Systems Manager jobs

IS Project Manager
We won't show you this job again
Added 1d ago
IS Project Manager
UW Health
Madison, Wisconsin
Clinical Support
Healthcare Administration
Human Resources
Nursing
$82k - $123k/yr
Hybrid
Master's degree in business
10,000+

Have you applied for this role?

IS Design Manager
We won't show you this job again
Added 2d ago
IS Design Manager
ENFRA
Boston, Massachusetts
Program Management
Project & Program Management
Project Management
$134k - $179k/yr
Bachelor's degree in architectural engineering
1,001-5,000

Have you applied for this role?

Manager, IS Project Management Office
We won't show you this job again
Added 3d ago
Manager, IS Project Management Office
HealthPoint (Washington)
Renton, Washington
Program Management
Project Management
Quality Assurance & Testing (QA Testing)
$126k - $213k/yr
Bachelor's degree in business administration
1,001-5,000

Have you applied for this role?

SAP IS-U ABAP Developer Manager - Resources/Utilities
We won't show you this job again
Added 6d ago
SAP IS-U ABAP Developer Manager - Resources/Utilities
Information Technology Senior Management Forum
Chicago, Illinois
Compensation & Benefits
Human Resources
Human Resources (HR) — Generalist
Learning & Development
$87k - $294k/yr
Military encouraged
51-200

Have you applied for this role?

IS Project Mgr Assoc
We won't show you this job again
Added 6d ago
IS Project Mgr Assoc
Baylor Scott & White Health
Dallas, Texas
Compliance & Legal
IT Support
Project Management
Technical Program Management
Bachelor's degree
10,000+

Have you applied for this role?

See All 73 Information Systems Manager Jobs

Find roles that match your experience and apply in just a few clicks.

Find Jobs

Information Systems Manager Job Market

Who's Hiring

  • HPC Industrial10
  • EY4
  • ENFRA4
  • Thompson Industrial Services3
  • Apple2

Top Industries Hiring

  • Healthcare & Medical Services
  • Education
  • Electronics & Hardware
  • Biotechnology & Pharmaceuticals
  • Consulting & Professional Services

What Employers Look For

The qualifications that appear most often in information systems manager jobs.

  • Bachelor's degree in information systems, computer science, or a related field
  • Five or more years of progressively responsible IT management experience
  • Proficiency with enterprise platforms such as ERP, CRM, or cloud infrastructure
  • Experience developing and enforcing IT policies, security controls, and compliance standards
  • PMP, ITIL, or CompTIA certifications are frequently listed as preferred qualifications
  • Strong communication skills for translating technical requirements to executive stakeholders

Tips for Your Information Systems Manager Job Search

Align your resume to IT governance frameworks

Hiring managers for information systems manager roles scan for ITIL, COBIT, or NIST references. If you've implemented or overseen any of these frameworks, name them explicitly in your resume rather than burying them in a generic 'managed IT operations' bullet.

Highlight budget and vendor management wins

Many candidates list technical skills but skip the business accountability piece. If you've owned an IT budget, negotiated contracts, or managed third-party vendors, call that out clearly. Employers weight those responsibilities heavily at the manager level.

Target postings by systems environment, not just title

An information systems manager role at a hospital running Epic EHR is a different job than one at a manufacturer running SAP. Filter openings by the core platforms listed, not just the title, so your application lands where your hands-on experience actually fits.

Apply early to roles that fit

Migrate Mate lists information systems manager openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Prepare a systems failure story for interviews

Interviewers for this role almost always ask how you've handled a critical outage or data integrity issue. Prepare a specific, structured account of what failed, what you did, and what changed afterward. Vague answers hurt credibility at this level.

Negotiate scope before discussing compensation

Before talking numbers, clarify the reporting structure, headcount you'll own, and capital authority. Managers who establish scope first negotiate from a stronger position and avoid accepting a director-level workload at a manager-level pay band.

Information Systems Manager Jobs: Frequently Asked Questions

Which companies are hiring the most information systems managers?

HPC Industrial, EY, and ENFRA are hiring the most information systems managers right now, with openings concentrated in Texas, Illinois, and California, based on current listings on Migrate Mate as of November 2026. Healthcare systems, federal contractors, and large financial institutions consistently post the highest volume of openings in this role.

How many information systems manager jobs are remote?

About 43% of information systems manager openings are fully remote or hybrid as of November 2026, though fully on-site roles remain common in regulated industries. Functions centered on IT strategy, vendor oversight, and policy governance tend to offer the most remote flexibility, while roles tied to on-premises infrastructure or physical data centers typically require regular in-office presence.

How do you become an information systems manager?

Start with a bachelor's degree in information systems, computer science, or a closely related field. Build several years of hands-on IT experience in areas like systems administration, network management, or business analysis before moving into a team lead or project lead role. From there, demonstrate budget ownership, vendor relationships, and cross-functional project delivery. Earning a certification such as ITIL or PMP strengthens your candidacy for formal management positions.

Can you get hired as an information systems manager without direct management experience?

It's possible if you've led projects, coordinated cross-functional teams, or owned a system implementation end to end, even without a formal direct-report structure. Employers in this space often treat technical lead roles and project ownership as equivalent management experience. Framing those responsibilities clearly on your resume, and backing them with outcomes like uptime improvements or cost reductions, closes a lot of the gap.

What does the information systems manager interview process look like?

Most employers run three to four rounds. An initial screening with HR or a recruiter focuses on your background and availability. A technical round with IT leadership covers your systems knowledge, security practices, and experience with their core platforms. A behavioral or case round asks how you've handled outages, budget decisions, or cross-departmental conflicts. Final interviews often include a presentation to senior leadership or a walkthrough of how you'd approach their environment.

Where can I find and apply to information systems manager jobs?

You can find and apply to information systems manager jobs on Migrate Mate, which lists current openings from across the United States. Search for roles that match your systems background, seniority level, and industry preference, then apply directly to each listing that fits.

See All 73 Information Systems Manager Jobs

Find roles that match your experience and apply in just a few clicks.

Find Jobs