Machine Learning Jobs in San Mateo, CA

Machine Learning jobs in San Mateo, California are concentrated in the Downtown Core, Hillsdale, and the Bay Meadows tech corridor, where fintech, enterprise software, and healthtech employers compete for ML talent year-round. Employers actively hiring right now include Roblox, BigHat Biosciences, and Skydio. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles1,114+
Top employerRoblox
Work type79% Hybrid
Top credentialBachelor's degree
Companies hiring10

Showing 5 of 1,114+ Machine Learning jobs

Upstart
Director of Product, Machine Learning & Decisioning Platforms
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Upstart
Added 1d ago
Director of Product, Machine Learning & Decisioning Platforms
Upstart
San Mateo, California
Project & Program Management
Solutions Engineering & Architecture
Technical Program Management
$216k - $299k/yr
Remote (US)
Bachelor's degree
1,001-5,000

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Roblox
Senior/Principal Platform Engineer, ML Platform
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Roblox
Added 2d ago
Senior/Principal Platform Engineer, ML Platform
Roblox
San Mateo, California
Compliance & Risk
Health & Safety
Project Management
$260k - $345k/yr
Bachelor's degree
1,001-5,000

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Roblox
Principal Machine Learning Engineer, Alt Defense
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Roblox
Added 1w ago
Principal Machine Learning Engineer, Alt Defense
Roblox
San Mateo, California
AI (Artificial Intelligence)
Data Science
$329k - $399k/yr
Doctoral degree in Computer Science
1,001-5,000

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BigHat Biosciences
Machine Learning Engineer
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BigHat Biosciences
Added 2w ago
Machine Learning Engineer
BigHat Biosciences
San Mateo, California
AI (Artificial Intelligence)
Cloud Engineering
Solutions Engineering & Architecture
$150k - $200k/yr
Hybrid
Master's degree

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BigHat Biosciences
Machine Learning Scientist
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BigHat Biosciences
Added 2w ago
Machine Learning Scientist
BigHat Biosciences
San Mateo, California
AI (Artificial Intelligence)
Cloud Engineering
Solutions Engineering & Architecture
$150k - $200k/yr
Hybrid
Doctoral degree in Computer Science

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See All 1,114+ Machine Learning Jobs in San Mateo

Find roles in San Mateo that match your experience and apply in just a few clicks.

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Machine Learning Job Market in San Mateo

Who's Hiring

  • Roblox
    Roblox650
  • BigHat Biosciences
    BigHat Biosciences93
  • Skydio
    Skydio46
  • Upstart
    Upstart46
  • Skild AI
    Skild AI46

Top Industries Hiring

  • Technology & Software511
  • Gaming & Esports46
  • Aerospace & Defense46
  • Artificial Intelligence46

Machine Learning Jobs in San Mateo: Frequently Asked Questions

How do I get a machine learning job in San Mateo?

Focus on San Mateo's fintech, enterprise SaaS, and healthtech employers, which drive the majority of local ML hiring. Roles concentrate in the Bay Meadows district and the Downtown Core, where mid-size technology companies tend to hire more actively than large enterprise names. Candidates with hands-on experience in recommendation systems, NLP, or production model deployment have a clear edge in this market.

Which companies hire machine learnings in San Mateo?

San Mateo machine learning roles are posted by Roblox, BigHat Biosciences, and Skydio and others right now, based on current listings on Migrate Mate as of September 2026. San Mateo's employer mix skews toward growth-stage fintech and data-driven SaaS companies that maintain dedicated ML teams rather than outsourcing the function.

Are there remote machine learning jobs in San Mateo?

Yes, though it depends on the role: model research and data pipeline work is commonly remote-friendly, while roles involving on-site infrastructure or embedded hardware are not. About 86% of machine learning openings tied to San Mateo are remote or hybrid as of September 2026, with hybrid schedules being most common among the fintech and SaaS employers headquartered here. Fully remote postings tend to come from companies using San Mateo as a registered location rather than a physical office.

How can I get a machine learning job in San Mateo with little or no experience?

The most realistic entry path in San Mateo is through data analyst or analytics engineer roles at local fintech and SaaS companies, which often serve as a direct pipeline into ML teams. Smaller Bay Meadows startups and growth-stage companies are more likely than large enterprises to hire junior ML engineers who can demonstrate strong Python skills and a portfolio of personal or open-source projects. Familiarity with the financial data use cases common in San Mateo's fintech cluster gives candidates a practical edge over generalist applicants.

Which industries hire the most machine learnings in San Mateo?

The sectors hiring the most machine learnings in San Mateo are Technology & Software, Gaming & Esports, and Aerospace & Defense, based on current listings on Migrate Mate as of September 2026. San Mateo's position as a hub for payments technology, digital lending, and B2B SaaS means these sectors consistently generate ML demand tied to fraud detection, personalization, and predictive analytics.

See All 1,114+ Machine Learning Jobs in San Mateo

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