ML Engineer Jobs in San Mateo, CA

ML Engineer jobs in San Mateo are concentrated in the Bay Meadows tech corridor, downtown San Mateo, and the Hillsdale district, with strong demand across fintech, enterprise software, and healthtech. Employers hiring right now include Roblox, BigHat Biosciences, and Skydio. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles1,027+
Top employerRoblox
Work type79% Hybrid
Top credentialBachelor's degree
Companies hiring10

Showing 5 of 1,027+ ML Engineer jobs

Upstart
Director of Product, Machine Learning & Decisioning Platforms
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Upstart
Added 1d ago
Director of Product, Machine Learning & Decisioning Platforms
Upstart
San Mateo, California
Project & Program Management
Solutions Engineering & Architecture
Technical Program Management
$216k - $299k/yr
Remote (US)
Bachelor's degree
1,001-5,000

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Roblox
Senior/Principal Platform Engineer, ML Platform
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Roblox
Added 2d ago
Senior/Principal Platform Engineer, ML Platform
Roblox
San Mateo, California
Compliance & Risk
Health & Safety
Project Management
$260k - $345k/yr
Bachelor's degree
1,001-5,000

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Roblox
Principal Machine Learning Engineer, Alt Defense
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Roblox
Added 1w ago
Principal Machine Learning Engineer, Alt Defense
Roblox
San Mateo, California
AI (Artificial Intelligence)
Data Science
$329k - $399k/yr
Doctoral degree in Computer Science
1,001-5,000

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BigHat Biosciences
Machine Learning Engineer
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BigHat Biosciences
Added 2w ago
Machine Learning Engineer
BigHat Biosciences
San Mateo, California
AI (Artificial Intelligence)
Cloud Engineering
Solutions Engineering & Architecture
$150k - $200k/yr
Hybrid
Master's degree

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BigHat Biosciences
Machine Learning Scientist
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BigHat Biosciences
Added 2w ago
Machine Learning Scientist
BigHat Biosciences
San Mateo, California
AI (Artificial Intelligence)
Cloud Engineering
Solutions Engineering & Architecture
$150k - $200k/yr
Hybrid
Doctoral degree in Computer Science

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See All 1,027+ ML Engineer Jobs in San Mateo

Find roles in San Mateo that match your experience and apply in just a few clicks.

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ML Engineer Job Market in San Mateo

Who's Hiring

  • Roblox
    Roblox599
  • BigHat Biosciences
    BigHat Biosciences86
  • Skydio
    Skydio43
  • Upstart
    Upstart43
  • Skild AI
    Skild AI43

Top Industries Hiring

  • Technology & Software471
  • Gaming & Esports43
  • Aerospace & Defense43
  • Artificial Intelligence43

ML Engineer Jobs in San Mateo: Frequently Asked Questions

How do I get a ml engineer job in San Mateo?

Focus on fintech, enterprise software, and healthtech employers, which drive the bulk of ml engineer hiring in San Mateo. The Bay Meadows corridor and downtown San Mateo are where most of these teams sit. Candidates who can demonstrate production ML experience, familiarity with large-scale data pipelines, and comfort working alongside data engineering and product teams stand out in this market.

Which companies hire ml engineers in San Mateo?

Companies currently hiring ml engineers in San Mateo include Roblox, BigHat Biosciences, and Skydio, per current listings on Migrate Mate as of September 2026. San Mateo's employer mix skews toward mid-size growth-stage tech firms and established financial technology companies, many of whom maintain dedicated applied ML teams.

Are there remote ml engineer jobs in San Mateo?

Yes, ml engineer roles are among the more remote-compatible technical positions because the core work involves modeling, experimentation, and code rather than on-site equipment. About 86% of ml engineer openings tied to San Mateo are remote or hybrid as of September 2026, with research and modeling work most likely to be fully remote. On-site expectations tend to apply for roles involving proprietary data infrastructure or close collaboration with hardware teams.

How can I get a ml engineer job in San Mateo with little or no experience?

The most realistic entry path in San Mateo is targeting data analyst or junior data scientist roles at the city's mid-size fintech and SaaS companies, which often promote into ML-focused positions once you demonstrate modeling skills. Building a public portfolio with end-to-end ML projects, contributing to open-source tools, and pursuing internships with San Mateo's growth-stage tech firms are concrete steps that local hiring managers respond to.

Which industries hire the most ml engineers in San Mateo?

Most ml engineer openings in San Mateo sit in Technology & Software, Gaming & Esports, and Aerospace & Defense, per current listings on Migrate Mate as of September 2026. San Mateo's position between Silicon Valley and San Francisco makes it a natural hub for fintech and enterprise software companies that rely heavily on predictive modeling and recommendation systems to drive their core products.

See All 1,027+ ML Engineer Jobs in San Mateo

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