Senior Level Principal Manufacturing Engineer Jobs

Senior level principal manufacturing engineer jobs place seasoned engineers at the helm of complex production systems, process architecture, and cross-functional teams driving measurable operational outcomes. Most openings are on-site or hybrid across Science & Research, Distribution & Wholesale, and Biotechnology & Pharmaceuticals, with employers like Laborie, Nextern, and Astellas hiring at this level now.

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Overview

Open roles9
Top stateMinnesota
Top employerLaborie
Top cityMaple Grove, MN
Work type100% On-site
Top industryScience

Showing 5 of 9+ Senior Level Principal Manufacturing Engineer jobs

Principal Manufacturing Engineer
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Principal Manufacturing Engineer
Amazon.com
Austin, Texas
Manufacturing Operations
Specialized Engineering
Mechanical Engineering
Industrial & Manufacturing Engineering
Engineering (Non-Software)
Industrial Engineering
Manufacturing Engineering
$163k - $221k/yr
On-Site
Bachelor's
10,000+

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AI Principal Solution Architect & Consultant – Smart Manufacturing & Operations - 69699
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AI Principal Solution Architect & Consultant – Smart Manufacturing & Operations - 69699
Hitachi Energy
Boston, Massachusetts
Business Strategy
Consulting & Professional Services
Project Management
10,000+

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Principal Manufacturing Engineer
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Principal Manufacturing Engineer
Nextern
Osseo, Minnesota
Industrial & Manufacturing Engineering
Quality Control
Manufacturing Engineering
$165k/yr
On-Site
Bachelor's

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Principal Manufacturing Engineer
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Principal Manufacturing Engineer
Nextern
Maple Grove, Minnesota
Industrial & Manufacturing Engineering
Manufacturing Engineering
$135k - $165k/yr
On-Site
Bachelor's

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Principal Manufacturing Engineer
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Principal Manufacturing Engineer
Laborie
Maple Grove, Minnesota
Manufacturing Operations
Quality Control
Specialized Engineering
Engineering (Non-Software)
Manufacturing Engineering
On-Site
Bachelor's

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See All 9 Senior Level Principal Manufacturing Engineer Jobs

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Senior Level Principal Manufacturing Engineer Job Market

Who's Hiring

Laborie2 open roles
Nextern2 open roles
Astellas1 open role

Top Industries Hiring

  • Science & Research
  • Distribution & Wholesale
  • Biotechnology & Pharmaceuticals
  • Consulting & Professional Services
  • Energy

Senior Level Principal Manufacturing Engineer Jobs: Frequently Asked Questions

How do I get a senior level principal manufacturing engineer job?

Employers at this level look for engineers who have owned end-to-end manufacturing processes, not just contributed to them. Demonstrating that you have driven cost reduction, yield improvement, or capital project delivery at scale matters more than credentials alone. Candidates who can show mentorship of junior engineers and cross-functional influence with operations, quality, and supply chain teams consistently stand out in the selection process.

Which companies hire senior level principal manufacturing engineers?

Companies hiring senior level principal manufacturing engineers right now include Laborie, Nextern, and Astellas, based on current listings on Migrate Mate as of November 2026. At this level, hiring tends to concentrate in large-scale manufacturers, aerospace and defense contractors, medical device companies, and industrial technology firms with complex, high-volume production environments.

Are there remote senior level principal manufacturing engineer jobs?

Yes, though most roles at this level require significant on-site presence given the hands-on nature of the work. About 0% of senior level principal manufacturing engineer openings are remote or hybrid as of November 2026, with hybrid arrangements most common for roles focused on systems design, NPI strategy, or program oversight rather than direct floor-level execution.

What makes a principal manufacturing engineer role senior level?

Senior level principal manufacturing engineer roles are defined by scope and ownership rather than task execution. Engineers at this stage set technical direction for manufacturing systems, own the outcomes of major capital or process improvement programs, and serve as the go-to authority for resolving systemic production challenges. Mentoring mid-level engineers and influencing decisions across quality, supply chain, and product development are expected parts of the job, not optional additions.

Which industries hire the most senior level principal manufacturing engineers?

Senior Level principal manufacturing engineer roles concentrate in Science & Research, Distribution & Wholesale, and Biotechnology & Pharmaceuticals, based on current listings on Migrate Mate as of November 2026. These sectors share a common need for engineers who can lead high-stakes process development, manage complex supply chains, and maintain rigorous quality and compliance standards at production scale.