Project Engineer Jobs in St. Louis, MO
Project Engineer jobs in St. Louis are in strong demand, concentrated in Cortex Innovation District, downtown, and Clayton, across construction, infrastructure, manufacturing, and energy. Employers hiring right now include Farnsworth, Mechanical Dynamics & Analysis, and Oates Associates. See the openings below and apply to the ones that match your experience.
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Showing 5 of 90+ Project Engineer jobs
Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.
How will you make an impact?
The Thermo Fisher Scientific St. Louis site is a multi-product and multi-client biopharmaceutical site with manufacturing facilities for pharmaceutical products for both (pre)clinical trials and commercial applications. The Staff Engineer role is part of the Engineering team and reports to the Manager of Manufacturing Engineering. This role focuses on managing and supporting capital projects to enhance our manufacturing capabilities and ensure compliance with GMP standards.
What you will do
- Manage contractors and capital projects up to $5MM.
- Develop and track scope, schedule, and budget for capital projects.
- Initiate, manage and close quality records related to capital projects.
- Drive closure of intermediate tasks on quality records to ensure departmental compliance and on-time completion.
- Author and Review GMP documents as required to support capital project objectives.
- Lead start-up and commissioning activities on capital projects.
- Ensure all capital projects comply with regulatory requirements, industry standards, and company policies.
- Collaborate with cross-functional teams including MSAT, PD, Quality, Operations, and Maintenance to ensure project alignment with business objectives.
- Conduct feasibility studies, prepare detailed project plans, and manage project timelines and budgets.
- Perform risk assessments and develop mitigation strategies to ensure successful project execution.
- Engage with business leadership as required for projects to attain business approval and ensure alignment of project deliverables with business objectives.
- Engage with customers and regulators as required for managed projects and areas of expertise.
- Drive adherence to site safety standards in delivering projects including applicable assessments of new facilities and equipment.
Education:
- Bachelor’s Degree or higher education in Engineering (Chemical, Mechanical, Electrical, Bio) and 5+ years experience, 8+ preferred.
- Associates Degree and 8+ years of related professional experience.
Experience
- 5+ years of pharmaceutical industry experience or experience in a similar industry
- Past experience managing contractors and projects up to $5MM
- Experience authoring documents in a GMP setting.
- Experience working in a cleanroom.
- Prior experience working on commissioning and validation in a pharmaceutical setting.
Knowledge, Skills, Abilities
- Knowledge of building codes and regulations.
- Understanding of regulatory requirements for pharmaceutical facilities.
- Excellent written and verbal communication
- Strong attention to detail
- Proficient with Microsoft Excel, Word, Outlook, Project and PowerPoint
- Proficient with AutoCad and Bluebeam
Benefits
We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!
Other
Relocation assistance is not provided.
Must be legally authorized to work in the United States now and in the future, without sponsorship.
Must be able to pass a comprehensive background check, which includes a drug screening.
Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
As part of the Thermo Fisher Scientific team, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provide our global teams with the resources needed to achieve individual career goals while helping to take science a step beyond by developing solutions for some of the world’s toughest challenges, like protecting the environment, making sure our food is safe or helping find cures for cancer.
How will you make an impact?
The Thermo Fisher Scientific St. Louis site is a multi-product and multi-client biopharmaceutical site with manufacturing facilities for pharmaceutical products for both (pre)clinical trials and commercial applications. The Staff Engineer role is part of the Engineering team and reports to the Manager of Manufacturing Engineering. This role focuses on managing and supporting capital projects to enhance our manufacturing capabilities and ensure compliance with GMP standards.
What you will do
- Manage contractors and capital projects up to $5MM.
- Develop and track scope, schedule, and budget for capital projects.
- Initiate, manage and close quality records related to capital projects.
- Drive closure of intermediate tasks on quality records to ensure departmental compliance and on-time completion.
- Author and Review GMP documents as required to support capital project objectives.
- Lead start-up and commissioning activities on capital projects.
- Ensure all capital projects comply with regulatory requirements, industry standards, and company policies.
- Collaborate with cross-functional teams including MSAT, PD, Quality, Operations, and Maintenance to ensure project alignment with business objectives.
- Conduct feasibility studies, prepare detailed project plans, and manage project timelines and budgets.
- Perform risk assessments and develop mitigation strategies to ensure successful project execution.
- Engage with business leadership as required for projects to attain business approval and ensure alignment of project deliverables with business objectives.
- Engage with customers and regulators as required for managed projects and areas of expertise.
- Drive adherence to site safety standards in delivering projects including applicable assessments of new facilities and equipment.
Education:
- Bachelor’s Degree or higher education in Engineering (Chemical, Mechanical, Electrical, Bio) and 5+ years experience, 8+ preferred.
- Associates Degree and 8+ years of related professional experience.
Experience
- 5+ years of pharmaceutical industry experience or experience in a similar industry
- Past experience managing contractors and projects up to $5MM
- Experience authoring documents in a GMP setting.
- Experience working in a cleanroom.
- Prior experience working on commissioning and validation in a pharmaceutical setting.
Knowledge, Skills, Abilities
- Knowledge of building codes and regulations.
- Understanding of regulatory requirements for pharmaceutical facilities.
- Excellent written and verbal communication
- Strong attention to detail
- Proficient with Microsoft Excel, Word, Outlook, Project and PowerPoint
- Proficient with AutoCad and Bluebeam
Benefits
We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation!
Other
Relocation assistance is not provided.
Must be legally authorized to work in the United States now and in the future, without sponsorship.
Must be able to pass a comprehensive background check, which includes a drug screening.
See All 90 Project Engineer Jobs in St. Louis
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Find Project Engineer JobsProject Engineer Job Market in St. Louis
Who's Hiring
- Farnsworth14
- Mechanical Dynamics & Analysis9
- Oates Associates7
- GFT5
- IMEG5
Top Industries Hiring
- Banking & Financial Services
- Consulting & Professional Services
Project Engineer Jobs in St. Louis: Frequently Asked Questions
How do I get a project engineer job in St. Louis?
Focus your search on St. Louis's strongest hiring sectors: heavy construction, civil infrastructure, industrial manufacturing, and utilities concentrated in the Cortex corridor and along the riverfront. General contractors, engineering and construction firms, and energy companies hire most actively here. Candidates with field experience on bridges, water systems, or plant expansions stand out locally. Tailoring your resume to specific project types common in the region gives you a clear edge over generalist applicants.
Which companies hire project engineers in St. Louis?
Employers hiring project engineers in St. Louis right now include Farnsworth, Mechanical Dynamics & Analysis, and Oates Associates, based on current listings on Migrate Mate as of November 2026. St. Louis draws a mix of large engineering and construction firms, regional utilities, and industrial manufacturers, all of which maintain ongoing project pipelines that require dedicated project engineering staff.
Are there remote project engineer jobs in St. Louis?
Yes, but with limitations. Project engineering is largely field- and site-oriented, so fully remote roles are uncommon for hands-on construction or manufacturing work. About 86% of project engineer openings tied to St. Louis are remote or hybrid as of November 2026, with most flexibility found in planning, scheduling, and documentation-heavy roles rather than on-site execution.
How can I get a project engineer job in St. Louis with little or no experience?
The most realistic entry path in St. Louis is through a project engineer intern or EIT role at a regional construction or civil engineering firm. Companies working on infrastructure projects for MoDOT, the Metropolitan Sewer District, and St. Louis County routinely hire entry-level candidates with engineering degrees. Starting as a field engineer or project coordinator at a general contractor in the metro area is a common stepping stone to a full project engineer title.
Which industries hire the most project engineers in St. Louis?
The sectors hiring the most project engineers in St. Louis are Banking & Financial Services and Consulting & Professional Services, based on current listings on Migrate Mate as of November 2026. St. Louis's ongoing investment in infrastructure renewal, industrial facility upgrades, and life sciences construction in the Cortex district keeps sustained demand across these sectors.
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See All 90 Project Engineer Jobs in St. Louis
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