Registered Nurse Jobs in San Diego, CA

Registered Nurse jobs in San Diego are in strong demand across Mission Valley, Kearny Mesa, and the Midway District, with deep hiring activity in acute care, outpatient clinics, and long-term care. Employers hiring right now include DESORT STAFFING, UC San Diego Health, and Kaiser Permanente. See the openings below and apply to the ones that match your experience.

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Overview

Open roles279+
Top employerDESORT STAFFING
Work type96% On-site
Top credentialBLS Certification
Companies hiring100+

Showing 5 of 279+ Registered Nurse jobs

Silverado
Full Time Hospice RN Case Manager (AM)
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Silverado
New 1m ago
Full Time Hospice RN Case Manager (AM)
Silverado
San Diego, California
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling
On-Site
1,001-5,000

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S
Registered Nurse (RN)
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S
New 1m ago
Registered Nurse (RN)
Shield Home Health & Hospice
San Diego, California
Business Development
Customer Success
Program Management
Project Management
BLS Certification

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Home Care Assistance
Private Duty Nurse (RN) – Concierge In-Home Care | Flexible Schedule | 1099 | SD
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Home Care Assistance
New 1m ago
Private Duty Nurse (RN) – Concierge In-Home Care | Flexible Schedule | 1099 | SD
Home Care Assistance
San Diego, California
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification

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TheKey Concierge Nursing
Private Duty Nurse (RN) – Concierge In-Home Care | Flexible Schedule | 1099 | SD
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TheKey Concierge Nursing
New 1m ago
Private Duty Nurse (RN) – Concierge In-Home Care | Flexible Schedule | 1099 | SD
TheKey Concierge Nursing
San Diego, California
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification

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V
Travel RN Oncology
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V
New 1m ago
Travel RN Oncology
Voyage Health
San Diego, California
Healthcare Administration
Nursing
Patient Services & Wellbeing

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Registered Nurse Job Market in San Diego

Who's Hiring

  • D
    DESORT STAFFING28
  • UC San Diego Health
    UC San Diego Health27
  • Kaiser Permanente
    Kaiser Permanente18
  • Rady Children's Hospital
    Rady Children's Hospital18
  • Sharp HealthCare
    Sharp HealthCare15

Top Industries Hiring

  • Healthcare & Medical Services69
  • Non-Profit & Social Services4
  • Consulting & Professional Services4
  • Medical Devices3
  • Electronics & Hardware3

Registered Nurse Jobs in San Diego: Frequently Asked Questions

How do I get a registered nurse job in San Diego?

The strongest hiring in San Diego comes from its large hospital networks, military-affiliated medical centers, and the growing cluster of outpatient and specialty clinics in Mission Valley and Kearny Mesa. Candidates with experience in med-surg, ICU, or emergency departments move fastest in this market. Prioritizing employers with high patient volumes and applying directly to posted openings gives you the clearest path to an offer.

Which companies hire registered nurses in San Diego?

Companies currently hiring registered nurses in San Diego include DESORT STAFFING, UC San Diego Health, and Kaiser Permanente, per current listings on Migrate Mate as of July 2026. San Diego's employer mix skews toward large health systems, federally affiliated medical facilities serving active-duty military and veterans, and an expanding network of outpatient surgery and specialty care centers.

Are there remote registered nurse jobs in San Diego?

Yes, though remote work is limited for most registered nurse roles given the hands-on nature of direct patient care. About 4% of registered nurse openings tied to San Diego are remote or hybrid as of July 2026, with those opportunities concentrated in utilization review, case management, and telephonic triage positions.

How can I get a registered nurse job in San Diego with little or no experience?

The most realistic entry path in San Diego is a new graduate residency program at one of the city's large hospital systems, which are structured to bring RNs from licensure to independent practice. Community hospitals in areas like Chula Vista and El Cajon also hire new grads more readily than flagship academic centers. Strong clinical rotation performance and a CEN or ACLS certification early on helps candidates stand out locally.

Which industries hire the most registered nurses in San Diego?

San Diego registered nurse roles concentrate in Healthcare & Medical Services, Non-Profit & Social Services, and Consulting & Professional Services, based on current listings on Migrate Mate as of July 2026. The combination of a large active-duty military population, a robust life sciences sector, and several major nonprofit health systems makes San Diego one of California's most consistent markets for nursing demand.

See All 279+ Registered Nurse Jobs in San Diego

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