Remote Principal Research Engineer Jobs
Remote principal research engineer jobs are actively hiring across the U.S., with remote-first firms and distributed research teams posting openings in technology, biotech, defense, and advanced computing. Employers currently hiring include Commence, G2, and ICF. Scan the live roles below and apply to whichever ones fit.
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Showing 5 of 19+ Remote Principal Research Engineer jobs
Company Overview:
Headquartered in suburban Atlanta, Georgia, Artivion, Inc. is a medical device company focused on developing simple, elegant solutions that address cardiac and vascular surgeons’ most difficult challenges in treating patients with aortic diseases. Artivion’s four major groups of products include: aortic stent grafts, surgical sealants, On-X mechanical heart valves, and implantable cardiac and vascular human tissues. Artivion has over 1,600 employees worldwide with sales representation in over 100 countries. The Company has manufacturing facilities located in Atlanta, Georgia, Austin, Texas and Hechingen, Germany. Additionally, it has sales and distribution offices in various countries throughout Europe, Asia, and South America. For additional information about Artivion, visit our website, www.artivion.com (http://www.artivion.com/).
Position Overview:
Manage assigned departmental projects and tasks in principle areas of responsibility, which are identified below for aortic arch repair technologies, including execution of investigational device exemption (IDE) studies.
Responsibilities:
- Serve as the primary owner of clinical studies, independently overseeing all study activities including stakeholder communication, team leadership, timeline execution, budget management, and issue resolution.
- Act as the main point of contact for assigned studies, leading cross-functional study team meetings and driving accountability across internal and external partners.
- Manage all study vendors, including qualification, onboarding, contract and budget oversight, invoicing, and escalation of operational issues.
- Develop clinical strategy for investigational device exemption (IDE) studies.
- Participate as a core team member, specifically collaborating with Regulatory, Quality, R&D, and Commercial stakeholders.
- Oversee day-to-day site operations at clinical sites to ensure clinical trials are conducted in compliance with protocols, contracts, GCP, and applicable regulatory requirements.
- Lead the development, review, and maintenance of clinical documentation, including protocols, study management plans, informed consent forms, case report forms, SOPs, and study amendments.
- Manage qualification, selection, and operations of study steering and safety committees.
- Plan and support quality initiatives to ensure study readiness for data analyses.
- Support the development of abstracts, manuscripts, and scientific presentations by coordinating with investigators and co-authors.
- Ensure timely preparation and completion of clinical study reports in alignment with regulatory and organizational deadlines.
- Develop and deliver study-related presentations for internal and external audiences.
- Interface with technical representatives, regional managers, and research teams to provide technical training and address clinical or customer-related inquiries.
- Facilitate regulatory submissions, including annual FDA reports and other required regulatory documentation.
- Serve as a reviewer for technical and marketing materials to ensure scientific accuracy and regulatory compliance.
- Collaborate with Quality and Risk Management partners to proactively identify, assess, and mitigate device risks.
- Support site recruitment and selection activities, investigator meetings, and site training initiatives.
- Perform basic statistical analyses to support product lines and clinical decision-making.
- Conduct literature reviews and prepare scientific summaries relevant to product development and clinical strategy.
- Attend national and international surgical and scientific congresses, in person or remotely, as required.
- Perform additional responsibilities, including duties executed at a level above current title, as assigned.
Qualifications:
- Minimum of a Bachelor’s degree, preferably a Master’s degree (in a related field).
- Minimum 10 years’ experience in clinical research or relevant experience, or advanced degree with 8 years’ experience.
- Experience with aortic repair technology (i.e. surgical grafts, endovascular devices) is highly desirable.
- Experience working on IDE studies is highly desirable.
- Experience working at a medical device company is highly desirable.
- Demonstrate project management, critical thinking, and communication skills.
- Demonstrated statistical and computer skills (spreadsheet, relational databases, intermediate to advanced statistical analysis).
- Excellent written and oral communication skills.
- Proficient knowledge of medical terminology.
- Willingness to travel.
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights (https://www.eeoc.gov/poster) notice from the Department of Labor.
Company Overview:
Headquartered in suburban Atlanta, Georgia, Artivion, Inc. is a medical device company focused on developing simple, elegant solutions that address cardiac and vascular surgeons’ most difficult challenges in treating patients with aortic diseases. Artivion’s four major groups of products include: aortic stent grafts, surgical sealants, On-X mechanical heart valves, and implantable cardiac and vascular human tissues. Artivion has over 1,600 employees worldwide with sales representation in over 100 countries. The Company has manufacturing facilities located in Atlanta, Georgia, Austin, Texas and Hechingen, Germany. Additionally, it has sales and distribution offices in various countries throughout Europe, Asia, and South America. For additional information about Artivion, visit our website, www.artivion.com (http://www.artivion.com/).
Position Overview:
Manage assigned departmental projects and tasks in principle areas of responsibility, which are identified below for aortic arch repair technologies, including execution of investigational device exemption (IDE) studies.
Responsibilities:
- Serve as the primary owner of clinical studies, independently overseeing all study activities including stakeholder communication, team leadership, timeline execution, budget management, and issue resolution.
- Act as the main point of contact for assigned studies, leading cross-functional study team meetings and driving accountability across internal and external partners.
- Manage all study vendors, including qualification, onboarding, contract and budget oversight, invoicing, and escalation of operational issues.
- Develop clinical strategy for investigational device exemption (IDE) studies.
- Participate as a core team member, specifically collaborating with Regulatory, Quality, R&D, and Commercial stakeholders.
- Oversee day-to-day site operations at clinical sites to ensure clinical trials are conducted in compliance with protocols, contracts, GCP, and applicable regulatory requirements.
- Lead the development, review, and maintenance of clinical documentation, including protocols, study management plans, informed consent forms, case report forms, SOPs, and study amendments.
- Manage qualification, selection, and operations of study steering and safety committees.
- Plan and support quality initiatives to ensure study readiness for data analyses.
- Support the development of abstracts, manuscripts, and scientific presentations by coordinating with investigators and co-authors.
- Ensure timely preparation and completion of clinical study reports in alignment with regulatory and organizational deadlines.
- Develop and deliver study-related presentations for internal and external audiences.
- Interface with technical representatives, regional managers, and research teams to provide technical training and address clinical or customer-related inquiries.
- Facilitate regulatory submissions, including annual FDA reports and other required regulatory documentation.
- Serve as a reviewer for technical and marketing materials to ensure scientific accuracy and regulatory compliance.
- Collaborate with Quality and Risk Management partners to proactively identify, assess, and mitigate device risks.
- Support site recruitment and selection activities, investigator meetings, and site training initiatives.
- Perform basic statistical analyses to support product lines and clinical decision-making.
- Conduct literature reviews and prepare scientific summaries relevant to product development and clinical strategy.
- Attend national and international surgical and scientific congresses, in person or remotely, as required.
- Perform additional responsibilities, including duties executed at a level above current title, as assigned.
Qualifications:
- Minimum of a Bachelor’s degree, preferably a Master’s degree (in a related field).
- Minimum 10 years’ experience in clinical research or relevant experience, or advanced degree with 8 years’ experience.
- Experience with aortic repair technology (i.e. surgical grafts, endovascular devices) is highly desirable.
- Experience working on IDE studies is highly desirable.
- Experience working at a medical device company is highly desirable.
- Demonstrate project management, critical thinking, and communication skills.
- Demonstrated statistical and computer skills (spreadsheet, relational databases, intermediate to advanced statistical analysis).
- Excellent written and oral communication skills.
- Proficient knowledge of medical terminology.
- Willingness to travel.
Equal Opportunity Employer
This employer is required to notify all applicants of their rights pursuant to federal employment laws. For further information, please review the Know Your Rights (https://www.eeoc.gov/poster) notice from the Department of Labor.
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Find JobsRemote Principal Research Engineer Job Market
Who's Hiring
Top Industries Hiring
- Technology & Software
- Non-Profit & Social Services
What Employers Look For
The qualifications that appear most often in remote principal research engineer jobs.
- PhD in computer science, electrical engineering, materials science, or a related technical field
- 8 or more years of applied research experience with peer-reviewed publications or patents
- Proficiency in Python, C++, or domain-specific simulation and modeling tools
- Demonstrated ability to lead and mentor cross-functional research teams independently
- Experience translating research prototypes into scalable production systems
- Familiarity with cloud computing platforms and high-performance computing environments
Tips for Your Remote Principal Research Engineer Job Search
Signal async research fluency upfront
Remote principal research engineer hiring managers look for candidates who document their thinking in writing. Your resume and cover materials should reference tools like Notion, Confluence, or shared research wikis and show you communicate complex findings clearly without relying on in-person discussion.
Highlight independent research outcomes explicitly
Remote employers can't observe how you work day to day, so your application must show self-directed results. Lead with outcomes you owned end to end: experiments you designed solo, papers you drove to publication, or prototypes you built without close supervision.
Apply early to remote roles that fit
Migrate Mate lists remote principal research engineer openings from across the U.S. in one place, so you can find roles that match your research domain and apply directly without sorting through location-filtered results on general boards.
Prepare for distributed team interview formats
Remote principal research engineer interviews often include asynchronous components, such as take-home research problems or recorded presentations reviewed by a panel across time zones. Practice delivering a concise research summary on video and expect written follow-up questions rather than a live back-and-forth.
Remote Principal Research Engineer Jobs: Frequently Asked Questions
How do I get a remote principal research engineer job?
Target companies with established distributed research teams, particularly remote-first technology firms, defense contractors with virtual labs, and biotech organizations with geographically spread R&D staff. Remote employers screen heavily for self-direction, rigorous written communication, and the ability to drive independent research with minimal synchronous check-ins. A strong publication record, open-source contributions, or documented research outcomes gives your application a clear edge over candidates who rely on in-person collaboration signals.
Which companies hire remote principal research engineers?
Employers currently hiring remote principal research engineers include Commence, G2, and ICF, per current remote listings on Migrate Mate as of November 2026. Remote openings for this role tend to cluster at remote-first technology companies, distributed AI and machine learning research labs, and large enterprise firms with fully virtual R&D divisions.
Can you get a remote principal research engineer job with no experience?
Yes, but remote entry into this role is harder because distributed teams expect you to operate independently from day one without on-the-job mentoring. Remote-first startups and open-source research organizations are more likely to consider candidates earlier in their careers. Demonstrating concrete research output, such as published papers, reproducible experiments, or documented personal projects, substitutes for formal experience and shows remote employers you can self-manage and produce results without supervision.
Do you need a degree for remote principal research engineer jobs?
Usually, but a graduate degree is not always required if your research output is strong and verifiable. Remote employers weigh published work, demonstrated expertise in a specialized domain, and evidence of independent research execution alongside formal credentials. A portfolio of real contributions, whether academic, industry, or open-source, can open doors even when your educational background does not follow a conventional path.
Which industries hire the most remote principal research engineers?
Remote principal research engineer roles concentrate in Technology & Software and Non-Profit & Social Services, based on current remote listings on Migrate Mate as of November 2026. These sectors hire principal research engineers remotely because their research programs operate across geographically distributed teams that depend on asynchronous collaboration and cloud-based research infrastructure.
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