Remote Substance Abuse Counselor Jobs
Remote Substance Abuse Counselor jobs are available nationwide at employers like Included Health and Entrada Therapeutics and other distributed teams, at every experience level. Find a role that fits below and apply directly.
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Location: Boston, MA
The Organization
What's happening at Entrada Therapeutics? Entrada is a clinical-stage biopharmaceutical company aiming to transform the lives of patients by establishing a new class of medicines that engage intracellular targets that have long been considered inaccessible. Through proprietary and versatile approaches, Entrada is advancing a robust development portfolio of genetic medicines for the potential treatment of neuromuscular and inherited retinal diseases, among others. Our lead oligonucleotide programs are in development for the potential treatment of people living with Duchenne muscular dystrophy (DMD) who are exon 44, 45, 50 and 51 skipping amenable. Entrada has partnered with Vertex Pharmaceuticals to develop a clinical-stage program, VX-670, for myotonic dystrophy type 1 (DM1).
2026 represents a catalyst-rich period for Entrada. We expect multiple clinical data readouts as we advance several DMD programs across the U.K., EU, and U.S. By year-end 2026, we anticipate four clinical-stage programs in our DMD franchise (ENTR-601-44, ENTR-601-45, ENTR-601-50, and ENTR-601-51). These programs are complemented by the ongoing clinical progress of our DM1 collaboration with Vertex (VX-670).
We are a tight-knit team of experts and leaders in both therapeutic development and rare diseases and are excited to grow and attract colleagues who are ready to join a high-energy, dedicated team that likes to get things done and dramatically improve the lives of patients and their families.
The Perfect Addition to Our Team
You are a motivated, resourceful, and enthusiastic Drug Substance Development & Manufacturing expert excited to support the company at a critical stage in its growth trajectory. You excel at peptide and/or oligonucleotide late-stage process development, GMP manufacturing and supply chain of drug substances. You thrive when performing these activities with minimal supervision in a collaborative matrix environment. At Entrada, you will not be siloed, but rather expected to interact across different functional groups, including Chemistry, Analytical, Drug Product, Quality, and CDMOs. Your ability and desire to thrive in a nimble, fast-paced results-driven environment will set you up for success.
The Opportunity
The Associate Director of Drug Substance Development and Manufacturing will lead and manage late-stage drug substance development for Entrada’s novel pipeline programs. This role will be instrumental in supporting development activities for clinical and commercial batches and ensuring validation parameters for manufacturing batches.
Responsibilities
- Facilitate timely execution, disposition, and release of intermediate/drug substance batches through detailed technical review of master batch records, executed batch records and other cGMP documentation.
- Partner with internal and external Quality Assurance, Quality Control and Technical Operations teams to execute late-stage development activities such as Process Characterization and Process Performance Qualifications.
- Act as a person-in-plant for smooth execution of critical manufacturing activities for clinical and commercial batches.
- Conduct risk assessments and develop mitigation strategies for manufacturing-related issues.
- Identify and resolve manufacturing issues and escalate appropriately to internal and/or joint governance if required.
- Implement and manage the Continuous Process Verification (CPV) program to ensure manufacturing process remain in a constant state of control and meet validated parameters.
- Author/review change controls to introduce process improvements through the lifecycle of programs from Phase 1 through Phase 3/validation and commercialization.
- Work closely with other internal functions including chemistry, analytical, quality control, quality assurance, DP, and regulatory affairs to ensure programs are effectively supported and high-quality standard maintained.
- Partner with Entrada team for CDMO due diligence during new CDMO selection to vet capabilities, risks and investments required.
- Author/review related sections in regulatory filing documents (IND, IMPD, NDA, BLA, MAA, etc.).
- Other tasks as assigned or as required for a given program.
The Necessities
At Entrada, our passion for science, our devotion to patients and our values drives our behavior:
- Humanity - We genuinely care about patients and about one another.
- Tenacity - We are relentless and persistent in the pursuit of developing therapies for patients.
- Creativity - We are creative problem solvers.
- Collaboration - We are more than the sum of our parts.
- Curiosity - We have a growth mindset and push conventional thought and theory.
To thrive on our team, you will need to come with:
- Master’s or suitable advanced degree in organic chemistry or other scientific or engineering discipline with 8+ years of related experience in pharmaceutical industry.
- Demonstrated proficiency in process development, tech transfer, scale-up, GMP manufacturing DS for clinical, and commercial supplies.
- Proficient in managing activities and resolving manufacturing challenges at CDMOs during routine cGMP manufacturing and process validations.
- Experienced in onboarding/managing/collaborating with CDMOs, raw material suppliers, testing partners, and other production partners.
- Hands-on experience in SPPS/SPOS, downstream purification and lyophilization is highly preferred.
- Demonstrated ability to develop and maintain production timelines and budgets.
- Up-to-date with industry practices and regulations (e.g. GxP, ISO, ICH, etc.) across multiple health authorities (e.g. FDA and EMA).
- Ability to interpret and relate Quality standards for implementation and review.
- Strong project management, interpersonal, communication, and problem-solving skills preferable.
- Ability to communicate clearly and professionally both in writing and verbally.
- Ability to travel up to 20% (domestic and international).
- This is a US based remote position with preference given to local New England based candidates. This role will require minimum monthly or quarterly travel to the Entrada Therapeutics Headquarters located in Boston, MA.
What We Offer: Meaningful Work, Fair Rewards, and Real Support
At Entrada Therapeutics, we understand that compensation and total rewards are a major consideration when exploring a new opportunity. We believe in transparency and equity and are committed to sharing salary ranges for every position, along with insight into our compensation philosophy, in accordance with certain state requirements in the United States and fostering a fair and open environment at the onset.
But we also know it is more than just pay. When you join Entrada, you’ll be part of a mission-driven team with access to comprehensive health, dental and vision coverage; life and disability insurance; with a 401(k) match. We pride ourselves on offering competitive benefits that empower our employees and reflect the value of their contributions – offering paid, gender-inclusive parental leave, holistic support for your health and well-being, education reimbursement, discretionary time off and commuting benefits aligned to your working model. If you find yourself working from our office in Boston’s Seaport District, this puts you steps away from some of the best the city has to offer.
“Our approach to compensation is grounded in transparency, equity and performance for the unique contributions each person brings. At Entrada, we know that meaningful work deserves meaningful reward — and we view compensation as one way we show appreciation for the collaboration, curiosity and commitment that drive our mission forward.”
— Kerry Robert, SVP of People
The salary for this opportunity ranges from $172,000-$202,000. The final base compensation offered will depend on several considerations which include but may not be limited to a candidate’s skills, competencies, experience and other job-related factors permitted by law. The final salary offered may fall outside of this range. #LI-JF1 #LI-Remote
Equal Opportunity Employer
Entrada Therapeutics is an equal opportunity employer. Qualified candidates will receive consideration for employment without regard to race, color, religion, national origin, gender, sexual orientation, gender identity or expression, age, mental or physical disability, and genetic information, marital status, citizenship status, military status, protected veteran status or any other category protected by law.
Third Party Staffing Agencies
Entrada does not accept unsolicited resumes from any source other than directly from candidates. For the protection of all parties involved in the recruiting process, resumes will only be accepted from recruiters/agencies if a signed agreement is in place at the inception of the recruiting effort and authorized for a specified position. Unsolicited resumes sent to Entrada from recruiters/agencies do not constitute any type of relationship between the recruiter/agency and Entrada and do not obligate Entrada to pay fees if we hire from those resumes.
Privacy Statement
Entrada Therapeutics, Inc. (the “Entrada,” “we,” “us,” or “our”) respects your privacy and we want you to be familiar with how we collect, use, share, or otherwise process, your Personal Information.
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Who's Hiring
- Included Health3

- Entrada Therapeutics1

Top Industries Hiring
- Technology & Software3
- Science & Research1
- Healthcare & Medical Services1
What Employers Look For
The qualifications that appear most often in remote substance abuse counselor jobs.
- Bachelor's or master's degree in counseling, social work, or a related field
- State licensure or certification such as CADC, LCDC, CSAC, or equivalent credential
- Experience with evidence-based practices including Motivational Interviewing and CBT
- Familiarity with electronic health records and case documentation systems
- Experience conducting individual and group counseling sessions with adult populations
- Knowledge of co-occurring mental health and substance use disorder treatment approaches
Tips for Your Remote Substance Abuse Counselor Job Search
List your certifications above your degree
Hiring managers scan for CADC, LCDC, or CSAC credentials before anything else. Put your licensure and certification status in the resume header or a dedicated credentials line, not buried under education. State-specific licenses belong front and center.
Tailor your resume to the client population
A substance abuse counselor resume for a veterans' treatment court reads differently than one for an adolescent residential program. Match your language and highlighted experience to the exact population the job posting names. Generic resumes get screened out fast.
Apply early to roles that fit
Migrate Mate lists substance abuse counselor openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Target postings by treatment modality
Filter your search by keywords like Motivational Interviewing, CBT, or MAT to find employers whose clinical approach matches your training. Applying where your modality experience aligns dramatically improves your callback rate and interview performance.
Prepare case scenario answers before interviews
Interviewers in this field routinely ask how you'd handle a client in denial, a relapse, or a dual-diagnosis crisis. Rehearse two or three specific case examples from your internship or work history so your answers are concrete and grounded in real practice.
Negotiate supervision hours into your offer
If you're working toward full licensure, ask during the offer stage whether the employer provides paid clinical supervision hours. Many agencies offer this but don't advertise it. Clarifying upfront saves you significant out-of-pocket cost and career time.
Remote Substance Abuse Counselor Jobs: Frequently Asked Questions
How do I get a remote substance abuse counselor job?
Target companies that already run distributed teams, since they hire remotely by default and know how to onboard someone they never meet in person. Remote substance abuse counselor employers screen hard for self-direction and clear written communication on top of the core skills, so show evidence you can own work without someone over your shoulder. Apply to the openings above that match your experience.
Which companies hire remote substance abuse counselors?
Companies hiring remote substance abuse counselors include Included Health and Entrada Therapeutics, based on current remote listings on Migrate Mate as of June 2026. Remote-first firms and large companies running distributed teams post the most remote substance abuse counselor roles.
Can you get a remote substance abuse counselor job with no experience?
Yes, but it is harder than an on-site role, because remote work expects you to operate independently from the start. Entry-level remote substance abuse counselor openings do exist, especially at remote-first companies, and a portfolio of real work helps more than a long resume. Applying broadly to the roles that fit improves your odds.
Do you need a degree for remote substance abuse counselor jobs?
Not always. Many employers hire remote substance abuse counselors on demonstrated skills and prior work rather than a specific degree, though some larger companies still prefer one. Showing relevant results matters more than a credential for most remote substance abuse counselor roles.
Which industries hire the most remote substance abuse counselors?
The sectors hiring the most remote substance abuse counselors are Technology & Software, Science & Research, and Healthcare & Medical Services, based on current remote listings on Migrate Mate as of June 2026. These sectors run distributed teams and hire substance abuse counselors remotely most consistently.
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