Scientist Jobs in Madison, WI
Scientist jobs in Madison, Wisconsin draw from a dense research corridor anchored in the University Research Park, the Near East Side biotech cluster, and the isthmus downtown, with strong demand across life sciences, agriculture-biotech, and medical research. Employers hiring right now include Arrowhead Pharmaceuticals, University of Wisconsin–Madison, and Abbott. Find a role that fits below and apply directly.
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Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing.
Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.
Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.
The Position
The Associate Manufacturing Scientist I (third shift) supports the production of drug substances and drug products. Their responsibility will focus on the preparation of solutions and reagents by following standard protocols. This technically focused second shift position supports lab work, helps solve problems, and effectively communicates with colleagues.
3rd shift work hours are 10 pm – 8:30 am and includes a 15% shift differential.
Responsibilities
- Follow batch records, SOPs, and work instructions to detail
- Document all operations in batch records and notebooks
- Comply with GMP protocols
- Assist other chemists within the CMC group during synthesis and chromatography of oligonucleotides including:
- Reagent solution preparation
- Column Packing
- Mobile phase preparation
- Fraction collection
- Operate TFF to desalt purified RNA solutions
- Operate a lyophilizer and package solid drug substance
- Execute processes as part of a team to ensure production timelines are kept and quality product is produced
- Maintain a clean work space
- Maintain safety by wearing required personal protective equipment
Requirements
- BS or MS in chemistry, biochemistry, engineering, or related scientific field
- Entry level to 3 years experience in a similar position
- Good verbal and written communication skills
- Ability to work in a team environment
- Ability to pay attention to detail
Preferred
- Experience working in a GMP setting with controlled documentation
Arrowhead provides competitive salaries and an excellent benefit package.
Candidates must have current, valid authorization to work in the country where this role is located.
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Who's Hiring
- Arrowhead Pharmaceuticals14

- University of Wisconsin–Madison11

- Abbott9

- Promega Corporation9

- Labcorp6

Scientist Jobs in Madison: Frequently Asked Questions
How do I get a scientist job in Madison?
Madison's strongest hiring comes from university-affiliated research centers, biotech and agri-science companies clustered in University Research Park, and medical research institutions on the Near East Side. Candidates with hands-on lab experience in life sciences, agricultural biology, or analytical chemistry stand out locally. Tailoring your application to show familiarity with Madison's research-driven environment, and connecting through UW-Madison's professional networks, gives you a real edge over generalist applicants.
Which companies hire scientists in Madison?
Madison scientist roles are posted by Arrowhead Pharmaceuticals, University of Wisconsin–Madison, and Abbott and others right now, based on current listings on Migrate Mate as of November 2026. Madison's employer mix leans heavily toward research-intensive organizations, including biotech firms, agricultural science companies, and academic medical centers with ongoing experimental programs.
Are there remote scientist jobs in Madison?
Yes, though remote availability is limited for most scientist roles since lab work, field sampling, and instrumentation require physical presence. About 67% of scientist openings tied to Madison are remote or hybrid as of November 2026, with flexibility concentrated in data analysis, regulatory science, and research writing roles rather than bench or field positions.
How can I get a scientist job in Madison with little or no experience?
The most realistic entry path in Madison is through research assistant or laboratory technician roles at UW-Madison-affiliated centers or the biotech companies in University Research Park, which regularly hire early-career candidates. Internships and co-op programs tied to the university pipeline feed directly into full-time openings. Building skills in data collection, sample processing, or regulatory documentation makes candidates competitive for these stepping-stone positions locally.
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