Scientist Jobs in Madison, WI

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Job summary:

The Topkara Laboratory in the Department of Medicine, Division of Cardiovascular Medicine at University of Wisconsin - Madison School of Medicine and Public Health is seeking to recruit an outstanding Scientist II to study transcriptional regulatory mechanisms of heart failure and myocardial recovery. Leveraging our cardiac tissue repository from patients undergoing left ventricular assist device (LVAD) implantation and cardiac transplantation, we utilize state-of-art techniques including high-throughput sequencing, computational genomics, human iPSC-derived cardiomyocytes, and genetically engineered mouse models to discover and characterize new gene targets for heart failure. Current projects are focusing on understanding the role of non-coding RNAs, RNA binding proteins, and RNA splicing regulation in heart failure and myocardial recovery. The Scientist II will perform experiments to characterize genetically modified mice models and delineate the mechanism of RNA processing dysregulation during heart failure.

• This position requires work to be completed onsite, at a designated campus work location.

Key job responsibilities:

• Serves as a unit subject matter expert and liaison to internal and external stakeholders providing advanced level information and representing the interests of a specialized research area

• Attends and assists with the facilitation of scholarly events and presentations in support of continued professional development and the dissemination of research information

• Collects and analyzes complex research data, conducts experiments and interviews, and documents results according to established policies and procedures under general supervision

• Writes or assists in developing grant applications and proposals to secure research funding

• Identifies research problems and develops complex research methodologies and procedures

• Conducts literature reviews, prepares reports and materials, and disseminates information to appropriate entities

• May supervise the day-to-day activities of a research unit as needed

Department:

School of Medicine and Public Health, Department of Medicine, Division of Cardiovascular Medicine, Topkara Lab

Fueled by innovation yet grounded in kindness, the Department of Medicine empowers leaders to transform medicine and improve lives everywhere. We are committed to professional fulfillment and health equity. We strive to ensure that everyone in our department understands the importance of social impact and belonging—and is empowered to champion it in all they do. Join us and be a part of supporting our nationally recognized faculty, innovative medical education programs and exceptional clinical care as we work towards our vision of healthy people and healthy communities!

At the Division of Cardiovascular Medicine, we help people live their healthiest lives through prevention and state-of-the-art care for complex heart disease. We lead comprehensive education, research and clinical programs—in partnership with our world-class university and remarkable health system. We are innovative, collaborative and kind. We strive for excellence and equity. And we make an impact in Wisconsin and beyond.

Compensation:

The starting salary wage for the position is $64,000 annually; but is negotiable based on experience and qualifications.

Employees in this position can expect to receive benefits such as generous vacation, holidays, and sick leave; competitive insurances and savings accounts; retirement benefits.

• SMPH Faculty /Academic Staff Benefits Flyer 2026

Required qualifications:

• Expertise in cellular and molecular biology techniques, cell culture and differentiation, and genetically engineered mouse models

• Research publications and presentations

• Experience in cardiovascular research and cardiac phenotyping

Preferred qualifications:

• Background in bioinformatic of high-throughput genetic data analysis including RNA sequencing and/or GWAS

Education:

Ph.D. in Biological Sciences, Healthcare, or closely related field is required by the start date of the position.

How to apply:

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Your cover letter should address how your training and experience aligns with the required and preferred qualifications listed above. Application reviewers will rely on these written materials to determine which applicants move forward in the process. References will be requested from final candidates. All applicants will be notified once the search concludes and a candidate is selected

Contact information:

Chanel Vang, clvang@medicine.wisc.edu, 608-263-1239

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Institutional statement on diversity:

Diversity is a source of strength, creativity, and innovation for UW-Madison. We value the contributions of each person and respect the profound ways their identity, culture, background, experience, status, abilities, and opinion enrich the university community. We commit ourselves to the pursuit of excellence in teaching, research, outreach, and diversity as inextricably linked goals.

The University of Wisconsin-Madison fulfills its public mission by creating a welcoming and inclusive community for people from every background - people who as students, faculty, and staff serve Wisconsin and the world.

The University of Wisconsin-Madison is an Equal Opportunity Employer.

Qualified applicants will receive consideration for employment without regard to, including but not limited to, race, color, religion, sex, sexual orientation, national origin, age, pregnancy, disability, or status as a protected veteran and other bases as defined by federal regulations and UW System policies. We promote excellence by acknowledging skills and expertise from all backgrounds and encourage all qualified individuals to apply.

To request a disability or pregnancy-related accommodation for any step in the hiring process (e.g., application, interview, pre-employment testing, etc.), please contact the Divisional Disability Representative (DDR) in the division you are applying to. Please make your request as soon as possible to help the university respond most effectively to you.

Employment may require a criminal background check. It may also require your references to answer questions regarding misconduct, including sexual violence and sexual harassment.

The University of Wisconsin System will not reveal the identities of applicants who request confidentiality in writing, except that the identity of the successful candidate will be released. See Wis. Stat. sec. 19.36(7).

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