Senior Director Regulatory Affairs Jobs in Missouri
Senior Director Regulatory Affairs jobs in Missouri are open across St. Louis, Kansas City, and Chesterfield and other Missouri metros, with employers like Washington University in St. Louis, Cushman & Wakefield, and Express Scripts Sales Operations hiring at every experience level. Find a role that fits below and apply directly.
Find JobsOverview
Showing 5 of 17+ Senior Director Regulatory Affairs jobs











Scheduled Hours
40
Position Summary
Provides operational leadership for WashU Medicine's delegated credentialing organization, special contracting and negotiation of managed care contract language. Works jointly with the Senior Director of Managed Care Financial Contracting and Rate Analysis to secure optimal terms of participation with third-party managed care organizations.
Job Description
Primary Duties & Responsibilities:
- Manages WashU Medicine's delegated credentialing organization.
- Manages WashU Physician’s Network (WUPN).
- Develops and implements policies and procedures pertaining to collection, and scope, of information required to carry out credentialing and re-credentialing functions.
- Designs and manages a centralized practitioner database and the mechanism for direct or indirect access by staff and representatives of affiliated organizations. Assures an accurate, complete, and well-documented information source.
- Maintains up-to-date knowledge of, and compliance with, credentialing standards established by the National Committee for Quality Assurance (NCQA), Joint Commission on the Accreditation of Healthcare Organization (JCAHO), Utilization Review Accreditation Commission (URAC), any state or federal medical staff credentialing requirements and the delegation agreement of any applicable care plans.
- Advises administrative staff of affiliated physician organizations, hospitals, managed care plans and other third parties on issues pertaining to credentialing and re-credentialing.
- Establishes and assures adherence to credentialing data confidentiality policy.
- Designs and conducts training and educational programs as required to assure credentialing compliance standards with hospital programs, delegated credentialing corporate representative, credentialing bodies and the internal committees.
- Develops infrastructure to assure the accuracy and consistency of the interface with the National Practitioner Data Bank (NPDB), Federation of State Medical Boards (FSMB) Medicare, Medicaid, medical schools, societies, and the Departments of Insurance or Health. Serves as authorized agent in reporting of adverse actions to any such organization.
- Designs and executes the pre-application, application and reapplication process associated with credentialing and re-credentialing. Provides direct oversight of site visit nurse responsible for assessment of physician’s office environment and medical records.
- Coordinates site audits by managed care plans, accrediting bodies and state or federal agencies.
- Leads medical school liaison for transplant contracting.
- Maintains operational oversight of WashU Medicine's single patient discount contracting service.
- Responsible for negotiation of managed care contract language and securing acceptable managed care language terms.
- Works jointly with the Senior Director of Managed Care Financial Contracting and Rate Analysis to secure optimal financial terms for all third-party agreements.
- Along with the Senior Director of Special Contracting and Contract Language, serves as the primary faculty practice plan liaison with BJC managed care contracting.
- Performs other duties as assigned.
Working Conditions:
Job Location/Working Conditions
- Normal office environment
Physical Effort
- Typically sitting at a desk or table
Equipment
- Office equipment
The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.
Required Qualifications
Education:
Bachelor's degree
Certifications/Professional Licenses:
No specific certification/professional license is required for this position.
Work Experience:
No specific work experience is required for this position.
Skills:
Not Applicable
Driver's License:
A driver's license is not required for this position.
More About This Job
WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.
Preferred Qualifications
Education:
Master's degree, Ph.D. - Doctor of Philosophy
Certifications/Professional Licenses:
No additional certification/professional licenses unless stated elsewhere in the job posting.
Work Experience:
Credentialing Management And Managed Care Contracting In A Large Faculty Practice, Private Practice, Large Healthcare Or Third-Party Payor Organization (5 Years)
Skills:
Analytical Thinking, Business, Conceptualize Ideas, Credentialing, Credential Management, Database Applications, External Partners, Finance, Interpersonal Interactions, Negotiation, Oral Communications, Provider Credentialing, Relational Database Management, Social Interaction, Spreadsheets, Word Processing Applications, Written Communication
Grade
G18
Salary Range
$129,800.00 - $228,400.00 / Annually
The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.
Questions
For frequently asked questions about the application process, please refer to our External Applicant FAQ.
Accommodation
If you are unable to use our online application system and would like an accommodation, please email CandidateQuestions@wustl.edu or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.
Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Benefits Statement
Personal
- Up to 22 days of vacation, 10 recognized holidays, and sick time.
- Competitive health insurance packages with priority appointments and lower copays/coinsurance.
- Take advantage of our free Metro transit U-Pass for eligible employees.
- WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.
Wellness
- Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!
Family
- We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.
- WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.
For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/
EEO Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, citizenship (where prohibited by federal law), age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.
See All 17 Senior Director Regulatory Affairs Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find JobsSenior Director Regulatory Affairs Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Senior Director Regulatory Affairs Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- Washington University in St. Louis3

- Cushman & Wakefield2

- Express Scripts Sales Operations2

- Kipp Nashville2

- MiTek2

Top Industries Hiring
- Consulting & Professional Services6
- Education6
- Construction & Real Estate2
- Manufacturing1
- Science & Research1
What Missouri Employers Look For
The qualifications that appear most often in senior director regulatory affairs jobs across Missouri.
- Bachelor's or advanced degree in life sciences, pharmacy, chemistry, or a related field
- 10 or more years of regulatory affairs experience in pharmaceutical, biotech, or medical device sectors
- Direct experience leading FDA submissions such as NDAs, BLAs, 510(k)s, or PMAs
- Demonstrated ability to manage cross-functional teams and lead regulatory strategy across product lifecycles
- Familiarity with ICH guidelines, 21 CFR regulations, and international regulatory frameworks
- Regulatory Affairs Certification (RAC) from RAPS preferred or required by many employers
Senior Director Regulatory Affairs Jobs in Missouri: Frequently Asked Questions
How many senior director regulatory affairs jobs are there in Missouri?
There are 17+ senior director regulatory affairs openings in Missouri on Migrate Mate as of June 2026, with the most roles in St. Louis, Kansas City, and Chesterfield. New positions post regularly as employers across Missouri hire.
How much do senior director regulatory affairses make in Missouri?
Senior director regulatory affairses in Missouri earn a median of about $67,270 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $44,060 for the lowest 10% to over $118,850 for the top 10%. Pay rises with experience, specialty, and employer.
Which Missouri cities have the most senior director regulatory affairs jobs?
St. Louis, Kansas City, and Chesterfield have the most senior director regulatory affairs openings in Missouri right now, with additional roles spread across smaller metros statewide.
Which companies hire senior director regulatory affairss in Missouri?
Employers hiring senior director regulatory affairss in Missouri include Washington University in St. Louis, Cushman & Wakefield, and Express Scripts Sales Operations, based on current listings on Migrate Mate as of June 2026.
Are there remote senior director regulatory affairs jobs in Missouri?
Yes. About 35% of senior director regulatory affairs openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.
How do I apply for senior director regulatory affairs jobs in Missouri?
You can apply to senior director regulatory affairs jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.
See All 17 Senior Director Regulatory Affairs Jobs in Missouri
Find roles in Missouri that match your experience and apply in just a few clicks.
Find Jobs