Senior Mainframe Systems Programmer Jobs in Massachusetts

Senior Mainframe Systems Programmer jobs in Massachusetts are open across Boston, Cambridge, and Waltham and other Massachusetts metros, with employers like Thermo Fisher Scientific, Amazon, and Klaviyo hiring at every experience level. Find a role that fits below and apply directly.

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Overview

Open roles2,668+
Top employerThermo Fisher Scientific
Top cityBoston, MA
Cities hiring133
Work type70% On-site
Top industryTechnology

Showing 5 of 2,668+ Senior Mainframe Systems Programmer jobs

University of Massachusetts Amherst
EDP Programmer II (Senior Desktop Support Technician)
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University of Massachusetts Amherst
Added 2w ago
EDP Programmer II (Senior Desktop Support Technician)
University of Massachusetts Amherst
Amherst, Massachusetts
IT Support & Systems Administration
Customer Service & Support
Technical Product & Program Management
IT Support
Customer Service
On-Site
Associate's
10,000+

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Humana
Senior Systems Engineer
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Humana
Added 5d ago
Senior Systems Engineer
Humana
Boston, Massachusetts
Software Engineering
Quality Assurance & Testing (QA Testing)
Cloud & DevOps
Automation QA
$98k - $134k/yr
Hybrid
Master's
10,000+

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NVIDIA
Senior System Architect
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NVIDIA
Added 1w ago
Senior System Architect
NVIDIA
Westford, Massachusetts
Software Engineering
Cloud & DevOps
Data Science & Analytics
Technical Product & Program Management
Data Science
$184k - $357k/yr
On-Site
Bachelor's

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NVIDIA
Senior System Architect
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NVIDIA
Added 2w ago
Senior System Architect
NVIDIA
Westford, Massachusetts
Solutions Engineering & Architecture
Cloud & DevOps
Technical Product & Program Management
Technical Program Management
$208k - $380k/yr
On-Site
Bachelor's

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Quanterix
Senior Systems Engineer
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Quanterix
Added 2w ago
Senior Systems Engineer
Quanterix
Billerica, Massachusetts
Specialized Engineering
Project & Program Management
Compliance & Legal
Engineering (Non-Software)
Project Management
$125k - $150k/yr
On-Site
Bachelor's
201-500

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See All 2,668+ Senior Mainframe Systems Programmer Jobs in Massachusetts

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Senior Mainframe Systems Programmer Jobs by City in Massachusetts

Where Massachusetts roles are concentrated, by current openings.

Boston
1,210 jobs
Cambridge
206 jobs
Waltham
127 jobs
Somerville
57 jobs
Burlington
53 jobs
Marlborough
44 jobs
Andover
43 jobs
Wilmington
38 jobs
Natick
37 jobs

Senior Mainframe Systems Programmer Job Market in Massachusetts

A snapshot from current Massachusetts openings, updated as new roles post.

Who's Hiring

  • Thermo Fisher Scientific
    Thermo Fisher Scientific107
  • Amazon
    Amazon65
  • Klaviyo
    Klaviyo55
  • State Street
    State Street55
  • Whoop
    Whoop55

Top Industries Hiring

  • Technology & Software462
  • Consulting & Professional Services435
  • Biotechnology & Pharmaceuticals340
  • Healthcare & Medical Services277
  • Science & Research260

What Massachusetts Employers Look For

The qualifications that appear most often in senior mainframe systems programmer jobs across Massachusetts.

  • 5 or more years of hands-on z/OS systems programming experience in a production environment
  • Proficiency with IBM system software installation and maintenance using SMP/E
  • Experience configuring and supporting JES2 or JES3, VTAM, and TCP/IP on z/OS
  • Working knowledge of RACF, ACF2, or Top Secret for mainframe security administration
  • Familiarity with DFSMS, DASD management, and storage subsystem configuration
  • Bachelor's degree in computer science, information systems, or a related technical field

Senior Mainframe Systems Programmer Jobs in Massachusetts: Frequently Asked Questions

How many senior mainframe systems programmer jobs are there in Massachusetts?

There are 2,668+ senior mainframe systems programmer openings in Massachusetts on Migrate Mate as of June 2026, with the most roles in Boston, Cambridge, and Waltham. New positions post regularly as employers across Massachusetts hire.

How much do senior mainframe systems programmers make in Massachusetts?

Senior mainframe systems programmers in Massachusetts earn a median of about $128,390 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $77,060 for the lowest 10% to over $168,310 for the top 10%. Pay rises with experience, specialty, and employer.

Which Massachusetts cities have the most senior mainframe systems programmer jobs?

Boston, Cambridge, and Waltham have the most senior mainframe systems programmer openings in Massachusetts right now, with additional roles spread across smaller metros statewide.

Which companies hire senior mainframe systems programmers in Massachusetts?

Employers hiring senior mainframe systems programmers in Massachusetts include Thermo Fisher Scientific, Amazon, and Klaviyo, based on current listings on Migrate Mate as of June 2026.

Are there remote senior mainframe systems programmer jobs in Massachusetts?

Yes. About 30% of senior mainframe systems programmer openings tied to Massachusetts are remote or hybrid as of June 2026. The rest are on-site roles based in Massachusetts metros.

How do I apply for senior mainframe systems programmer jobs in Massachusetts?

You can apply to senior mainframe systems programmer jobs in Massachusetts directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Massachusetts location, then apply to each one that fits.

See All 2,668+ Senior Mainframe Systems Programmer Jobs in Massachusetts

Find roles in Massachusetts that match your experience and apply in just a few clicks.

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