Senior Level Senior Quality Manager Jobs
Senior level senior quality manager jobs place experienced professionals in charge of quality systems strategy, cross-functional audit programs, and the teams that execute corrective and preventive action at scale. Openings concentrate across Biotechnology & Pharmaceuticals, Technology & Software, and Electronics & Hardware, with 16% offering remote or hybrid work, and employers like Amazon, NVIDIA, and Amazon Web Services hiring at this level now.
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Position Summary:
ultrainnovative – Tackle rare and dynamic challenges
The Senior QC Analyst position will execute an interdisciplinary set of testing (e.g. microbiology testing, molecular biology testing and bioassay testing) and laboratory operations (e.g. sample management) to support AAV-based gene therapy manufacturing operations on a shift. The incumbent will demonstrate strengths in leadership in the lab with a focus on sound independent thinking and a self-motivated mindset to drive actions forward.
In addition, the Senior QC Analyst I will review, enter and approve analytical data generated internally and from external laboratories. Routine work includes release and stability testing, critical reagent qualification, quality system ownership (e.g. OOS investigations, deviations, CAPA, change controls), method validation and transfer, critical reagent qualification, analyze data, and author technical documents.
Work Model:
Core Lab & Ops: This role typically requires that the majority of the work be conducted on-site.
Responsibilities:
- Performs routine QC testing in a GMP environment to support product release and stability including but not limited to; cell-based assays, quantitative PCR, ELISA, and microbiological test methods (e.g. bioburden testing, plate reading, endotoxin testing, total organic carbon testing, conductivity testing, media growth promotion).
- Executes sample management in support of GMP manufacturing including, but not limited to, incoming sample receipt, sample aliquoting, sample transactions in LIMS, sample distribution to testing laboratories and sample disposal.
- Review and approval of cGMP analytical data for release and stability testing
- Supports and leads QC Bioassay laboratory operations (ex. Instrument qualification and maintenance. Passage cells, qualify critical reagents, etc).
- Author and support quality events; Change controls, Deviation, CAPA, OOS Investigation, as needed.
- Support method transfer and validation activities for development, technical transfer, and validation of late-stage assays for AAV-based gene therapy programs.
- Author analytical method performance trend reports, as needed.
- Write, prepare, and present technical data, technical reports, and standard operating procedures (SOPs).
- Model leadership behaviors and mentor/train junior staff
- Work with cross functional teams with both internal and external stakeholders
Requirements:
- BS in Cell Biology, Molecular Biology, Biochemistry or a related discipline with minimum 6-8+ years industry experience or MS with 4-6 years' experience.
- 4+ Experience in a GMP/GLP environment is a must.
- Experience in routine mammalian cell culture required
- Experience with quantitative PCR required. Experience with cell-based potency assays is required. Experience performing immunoassays such as ELISAs strongly desired
- Experience with statistical analysis (SoftMax, JMP) and LIMS (LabVantage) preferred
- Ability and desire to work in a fast-paced environment
- Strong collaboration, team-working skills, and communication skills
- Independently motivated and detail-oriented with good problem-solving ability
- Strong communication, interpersonal and organizational skills
Physical Demand Requirements
- Stand for extended periods of time with periodic stooping / bending / kneeling
- Able to lift, push, pull up to 50lbs.
- Climb ladders and stairs of various heights.
- Work in a lab environment requiring special protective clothing over the head, face, hands, feet, and body. This role requires the ability to wear personal protective equipment.
- Certain tasks may require use of a respirator; medical clearance will be required in advance.
#LI-AJ1 #LI-Onsite
- Generous vacation time and public holidays observed by the company
- Volunteer days
- Long term incentive and Employee stock purchase plans or equivalent offerings
- Employee wellbeing benefits
- Fitness reimbursement
- Tuition sponsoring
- Professional development plans
- Benefits vary by region and country
Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at talentacquisition@ultragenyx.com.
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Position Summary:
ultrainnovative – Tackle rare and dynamic challenges
The Senior QC Analyst position will execute an interdisciplinary set of testing (e.g. microbiology testing, molecular biology testing and bioassay testing) and laboratory operations (e.g. sample management) to support AAV-based gene therapy manufacturing operations on a shift. The incumbent will demonstrate strengths in leadership in the lab with a focus on sound independent thinking and a self-motivated mindset to drive actions forward.
In addition, the Senior QC Analyst I will review, enter and approve analytical data generated internally and from external laboratories. Routine work includes release and stability testing, critical reagent qualification, quality system ownership (e.g. OOS investigations, deviations, CAPA, change controls), method validation and transfer, critical reagent qualification, analyze data, and author technical documents.
Work Model:
Core Lab & Ops: This role typically requires that the majority of the work be conducted on-site.
Responsibilities:
- Performs routine QC testing in a GMP environment to support product release and stability including but not limited to; cell-based assays, quantitative PCR, ELISA, and microbiological test methods (e.g. bioburden testing, plate reading, endotoxin testing, total organic carbon testing, conductivity testing, media growth promotion).
- Executes sample management in support of GMP manufacturing including, but not limited to, incoming sample receipt, sample aliquoting, sample transactions in LIMS, sample distribution to testing laboratories and sample disposal.
- Review and approval of cGMP analytical data for release and stability testing
- Supports and leads QC Bioassay laboratory operations (ex. Instrument qualification and maintenance. Passage cells, qualify critical reagents, etc).
- Author and support quality events; Change controls, Deviation, CAPA, OOS Investigation, as needed.
- Support method transfer and validation activities for development, technical transfer, and validation of late-stage assays for AAV-based gene therapy programs.
- Author analytical method performance trend reports, as needed.
- Write, prepare, and present technical data, technical reports, and standard operating procedures (SOPs).
- Model leadership behaviors and mentor/train junior staff
- Work with cross functional teams with both internal and external stakeholders
Requirements:
- BS in Cell Biology, Molecular Biology, Biochemistry or a related discipline with minimum 6-8+ years industry experience or MS with 4-6 years' experience.
- 4+ Experience in a GMP/GLP environment is a must.
- Experience in routine mammalian cell culture required
- Experience with quantitative PCR required. Experience with cell-based potency assays is required. Experience performing immunoassays such as ELISAs strongly desired
- Experience with statistical analysis (SoftMax, JMP) and LIMS (LabVantage) preferred
- Ability and desire to work in a fast-paced environment
- Strong collaboration, team-working skills, and communication skills
- Independently motivated and detail-oriented with good problem-solving ability
- Strong communication, interpersonal and organizational skills
Physical Demand Requirements
- Stand for extended periods of time with periodic stooping / bending / kneeling
- Able to lift, push, pull up to 50lbs.
- Climb ladders and stairs of various heights.
- Work in a lab environment requiring special protective clothing over the head, face, hands, feet, and body. This role requires the ability to wear personal protective equipment.
- Certain tasks may require use of a respirator; medical clearance will be required in advance.
#LI-AJ1 #LI-Onsite
- Generous vacation time and public holidays observed by the company
- Volunteer days
- Long term incentive and Employee stock purchase plans or equivalent offerings
- Employee wellbeing benefits
- Fitness reimbursement
- Tuition sponsoring
- Professional development plans
- Benefits vary by region and country
Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at talentacquisition@ultragenyx.com.
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
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Find JobsSenior Level Senior Quality Manager Job Market
Who's Hiring
- Amazon14
- NVIDIA10
- Amazon Web Services7
- GoodLeap6
- Horrocks6
Top Industries Hiring
- Biotechnology & Pharmaceuticals57
- Technology & Software56
- Electronics & Hardware33
- Consulting & Professional Services31
- Manufacturing27
Senior Level Senior Quality Manager Jobs: Frequently Asked Questions
How do I get a senior level senior quality manager job?
Candidates who stand out at this level demonstrate ownership of enterprise-wide quality management systems, not just participation in them. Hiring managers look for experience leading cross-functional teams through major audits, regulatory submissions, or system overhauls. Certifications like ASQ CQM/OE or CQE strengthen your profile, but what gives a real edge is showing measurable outcomes from quality initiatives you led, not just supported.
Which companies hire senior level senior quality managers?
Companies hiring senior level senior quality managers right now include Amazon, NVIDIA, and Amazon Web Services, based on current listings on Migrate Mate as of June 2026. Hiring at this level tends to come from manufacturers, life sciences organizations, aerospace firms, and industrial companies that operate under strict regulatory or customer quality requirements.
Are there remote senior level senior quality manager jobs?
Yes, though remote availability varies by industry and role scope. About 16% of senior level senior quality manager openings are remote or hybrid as of June 2026, with hybrid arrangements being more common in sectors where on-site audits, lab oversight, or supplier visits are part of the job. Fully remote roles tend to appear more often in software quality and consulting contexts.
What makes a senior quality manager role senior level?
Senior level roles carry ownership over the quality function rather than execution within it. That means defining quality policy, leading internal and external audits, mentoring junior quality professionals, and influencing decisions at the director or VP level. The scope typically covers multiple product lines, facilities, or supplier networks, and the expectation is that you resolve systemic quality issues independently rather than escalating them.
Which industries hire the most senior level senior quality managers?
Senior Level senior quality manager roles concentrate in Biotechnology & Pharmaceuticals, Technology & Software, and Electronics & Hardware, based on current listings on Migrate Mate as of June 2026. These sectors drive demand because they operate under rigorous regulatory frameworks, customer audit requirements, or compliance standards that require experienced quality leadership to maintain certification and manage risk at scale.