Software Systems Engineer Jobs in Delaware

The Lead Image Chain Systems Engineer (Detector Integration) is a senior technical leader responsible for advancing Hologic’s x-ray imaging platforms through innovation in detector subsystems and full image chain optimization.

This role drives the exploration, development, improvement, and integration of x-ray detectors and sensor architectures, delivering measurable system-level performance improvements and new acquisition modes across mammography, DXA, and specimen imaging platforms.

You will operate as a hands-on expert and mentor, setting technical direction, executing complex R&D programs, and collaborating cross-functionally to deliver robust, compliant solutions aligned with Hologic’s technology roadmap. This role is located in Newark, DE.

At Hologic, we’re redefining what’s possible in diagnostic imaging—and we need your expertise to make it happen. As a Lead Image Chain Systems Engineer, you’ll be at the forefront of innovation, designing next-generation imaging platforms that combine advanced x-ray hardware with powerful image processing software. Your work will directly impact patient care by delivering crystal-clear images with maximum safety and efficiency.

What You’ll Do:

• Lead development, test, and integration of x-ray detectors and sensor solutions across multiple product platforms
• Drive innovation in detector designs, readout schemes, and performance‑enhancing modes.
• Drive innovation in detector architectures, readout electronics, and performance-enhancing acquisition modes
• Lead end‑to‑end signal‑chain development, including analog front‑end, digitization, calibration, and dose management.
• Evaluate and mature new detector technologies and architectures
• Support pre‑processing pipelines, from flat‑field optimization to advanced image‑quality enhancement.
• Establish and execute image‑quality metrics and test methods.
• Deliver system-level performance improvements through signal processing and calibration techniques
• Guide alignment of detector technologies with platform system architectures
• Support prototyping, benchtop testing, and early-stage system integration
• Lead initiatives while remaining hands-on through design, bring-up, validation, and technology transfer
• Collaborate cross‑functionally to deliver robust, compliant solutions in a regulated environment.
• Support IP strategy, risk management, requirements, design reviews, and verification documentation.

What We’re Looking For:

We are seeking a hands-on senior systems engineer with deep expertise in x-ray detectors and imaging systems, capable of translating technology innovation into clinically impactful imaging performance improvements.

What Sets You Apart:

• Ability to bridge hardware, physics, and software domains
• Passion for innovation in medical imaging technology
• Strong leadership combined with hands-on execution
• Customer- and patient-centered mindset

Knowledge

• Understanding of medical imaging systems, including x-ray physics, x-ray tubes, digital detectors, and basis of image processing algorithms.
• Proficiency in detector signal chain design, encompassing, x-ray conversion materials, pixel sensor backplanes, analog front-end amplifiers, digitization, timing, calibration, and noise modeling & management.
• Practical experience with detector embedded HW/SW systems and readout schemes architectures, and performance optimization.
• Knowledge of hardware/software interoperability and the design of scalable, modular technology platforms.
• Experience with front-end technology exploration, proof-of-concept development, and early-stage system integration & validation.
• Familiarity with regulatory standards for medical devices (IEC 60601, ISO 13485, FDA design controls) and risk management practices.
• Experience with system engineering principles, requirements development, and integration of complex medical imaging systems.
• Competence in technology transfer, documentation, and cross-functional product development processes.

Skills

• Strong system-level problem-solving and root cause analysis
• HW acumen and solid embedded and application SW skills
• Proficiency in Python, C++, MATLAB, or similar
• Ability to lead multidisciplinary technical projects
• Excellent communication and technical documentation skills
• Hands-on experience with prototyping, validation, and performance optimization

Behavior

• Demonstrates a proactive, innovative mindset with a passion for advancing healthcare technology.
• Exhibits strong leadership and ownership of projects, driving results with minimal supervision.
• Embraces collaboration and open communication to foster cross-functional teamwork.
• Maintains a high level of accountability, integrity, and attention to detail in all aspects of work.
• Adapts quickly to changing priorities and thrives in dynamic, fast-paced environments.
• Champions continuous learning and professional development to stay ahead of industry trends.
• Values customer-centric thinking, ensuring solutions align with clinical needs and patient safety.
• Promotes a culture of excellence, quality, and compliance within the organization.

Qualifications:

Education

BS or MS in Electrical Engineering, Biomedical Engineering, Physics, Computer Engineering/Science, or related field.

Experience

• 10+ years of experience in x‑ray imaging systems with demonstrated ownership of detector‑centric programs.
• Hands‑on development and commercialization experience with medical devices & systems
• Experience across early technology exploration, new product development, and design controls in regulated medical device environments.
• Experience leading technical teams or sub‑teams while remaining hands‑on.
• Track record adapting technologies to common platform architectures and creating reusable modules/components.
• Experience with IP generation (disclosures, patents) and technology partnerships with suppliers and academia.

So why join Hologic?

We are committed to making Hologic the company where top talent comes to grow. For you to succeed, we want to enable you with the tools and knowledge required and so we provide comprehensive training when you join as well as continued development and training throughout your career. We offer a competitive salary and annual bonus scheme, one of our talent partners can discuss this in more detail with you.

The annualized base salary range for this role $119,300 - $186,600 and is bonus eligible. Final compensation packages will ultimately depend on factors including relevant experience, skillset, knowledge, geography, education, business needs and market demand.

Agency and Third-Party Recruiter Notice: Agencies that submit a resume to Hologic must have a current executed Hologic Agency Agreement executed by a member of the Human Resource Department. In addition Agencies may only submit candidates to positions for which they have been invited to do so by a Hologic Recruiter. All resumes must be sent to the Hologic Recruiter under these terms or they will not be considered.

As part of our commitment to a fair and accurate evaluation of each candidate's qualifications, we require all applicants to refrain from using AI tools, such as generative AI or automated writing assistance, during any stage of the interview process. Responses influenced by AI may result in disqualification. We appreciate your understanding and cooperation in ensuring a transparent and equitable selection process.

Hologic, Inc. is proud to be an Equal Opportunity Employer inclusive of disability and veterans.

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