Systems Development Engineer Jobs in Delaware
Systems Development Engineer jobs in Delaware are concentrated in the financial services, life sciences, and defense contracting sectors, with steady demand at mid-level through senior and staff engineer levels. Most hiring activity is in Wilmington, Newark, and Dover, where established employers like JPMorgan Chase, DuPont, and Lockheed Martin maintain significant operations and engineering teams. The most sought-after specialties in Delaware are cloud infrastructure automation, CI/CD pipeline development, and distributed systems tooling. Find a role that fits below and apply directly.
Find JobsOverview
Showing 5 of 21+ Systems Development Engineer jobs









The Lead Image Chain Systems Engineer (Detector Integration) is a senior technical leader responsible for advancing Hologic’s x-ray imaging platforms through innovation in detector subsystems and full image chain optimization.
This role drives the exploration, development, improvement, and integration of x-ray detectors and sensor architectures, delivering measurable system-level performance improvements and new acquisition modes across mammography, DXA, and specimen imaging platforms.
You will operate as a hands-on expert and mentor, setting technical direction, executing complex R&D programs, and collaborating cross-functionally to deliver robust, compliant solutions aligned with Hologic’s technology roadmap. This role is located in Newark, DE.
At Hologic, we’re redefining what’s possible in diagnostic imaging—and we need your expertise to make it happen. As a Lead Image Chain Systems Engineer, you’ll be at the forefront of innovation, designing next-generation imaging platforms that combine advanced x-ray hardware with powerful image processing software. Your work will directly impact patient care by delivering crystal-clear images with maximum safety and efficiency.
What You’ll Do:
- Lead development, test, and integration of x-ray detectors and sensor solutions across multiple product platforms
- Drive innovation in detector designs, readout schemes, and performance‑enhancing modes.
- Drive innovation in detector architectures, readout electronics, and performance-enhancing acquisition modes
- Lead end‑to‑end signal‑chain development, including analog front‑end, digitization, calibration, and dose management.
- Evaluate and mature new detector technologies and architectures
- Support pre‑processing pipelines, from flat‑field optimization to advanced image‑quality enhancement.
- Establish and execute image‑quality metrics and test methods.
- Deliver system-level performance improvements through signal processing and calibration techniques
- Guide alignment of detector technologies with platform system architectures
- Support prototyping, benchtop testing, and early-stage system integration
- Lead initiatives while remaining hands-on through design, bring-up, validation, and technology transfer
- Collaborate cross‑functionally to deliver robust, compliant solutions in a regulated environment.
- Support IP strategy, risk management, requirements, design reviews, and verification documentation.
What We’re Looking For:
We are seeking a hands-on senior systems engineer with deep expertise in x-ray detectors and imaging systems, capable of translating technology innovation into clinically impactful imaging performance improvements.
What Sets You Apart:
- Ability to bridge hardware, physics, and software domains
- Passion for innovation in medical imaging technology
- Strong leadership combined with hands-on execution
- Customer- and patient-centered mindset
Knowledge
- Understanding of medical imaging systems, including x-ray physics, x-ray tubes, digital detectors, and basis of image processing algorithms.
- Proficiency in detector signal chain design, encompassing, x-ray conversion materials, pixel sensor backplanes, analog front-end amplifiers, digitization, timing, calibration, and noise modeling & management.
- Practical experience with detector embedded HW/SW systems and readout schemes architectures, and performance optimization.
- Knowledge of hardware/software interoperability and the design of scalable, modular technology platforms.
- Experience with front-end technology exploration, proof-of-concept development, and early-stage system integration & validation.
- Familiarity with regulatory standards for medical devices (IEC 60601, ISO 13485, FDA design controls) and risk management practices.
- Experience with system engineering principles, requirements development, and integration of complex medical imaging systems.
- Competence in technology transfer, documentation, and cross-functional product development processes.
Skills
- Strong system-level problem-solving and root cause analysis
- HW acumen and solid embedded and application SW skills
- Proficiency in Python, C++, MATLAB, or similar
- Ability to lead multidisciplinary technical projects
- Excellent communication and technical documentation skills
- Hands-on experience with prototyping, validation, and performance optimization
Behavior
- Demonstrates a proactive, innovative mindset with a passion for advancing healthcare technology.
- Exhibits strong leadership and ownership of projects, driving results with minimal supervision.
- Embraces collaboration and open communication to foster cross-functional teamwork.
- Maintains a high level of accountability, integrity, and attention to detail in all aspects of work.
- Adapts quickly to changing priorities and thrives in dynamic, fast-paced environments.
- Champions continuous learning and professional development to stay ahead of industry trends.
- Values customer-centric thinking, ensuring solutions align with clinical needs and patient safety.
- Promotes a culture of excellence, quality, and compliance within the organization.
Qualifications:
Education
BS or MS in Electrical Engineering, Biomedical Engineering, Physics, Computer Engineering/Science, or related field.
Experience
- 10+ years of experience in x‑ray imaging systems with demonstrated ownership of detector‑centric programs.
- Hands‑on development and commercialization experience with medical devices & systems
- Experience across early technology exploration, new product development, and design controls in regulated medical device environments.
- Experience leading technical teams or sub‑teams while remaining hands‑on.
- Track record adapting technologies to common platform architectures and creating reusable modules/components.
- Experience with IP generation (disclosures, patents) and technology partnerships with suppliers and academia.
So why join Hologic?
We are committed to making Hologic the company where top talent comes to grow. For you to succeed, we want to enable you with the tools and knowledge required and so we provide comprehensive training when you join as well as continued development and training throughout your career. We offer a competitive salary and annual bonus scheme, one of our talent partners can discuss this in more detail with you.
The annualized base salary range for this role $119,300 - $186,600 and is bonus eligible. Final compensation packages will ultimately depend on factors including relevant experience, skillset, knowledge, geography, education, business needs and market demand.
Agency and Third-Party Recruiter Notice: Agencies that submit a resume to Hologic must have a current executed Hologic Agency Agreement executed by a member of the Human Resource Department. In addition Agencies may only submit candidates to positions for which they have been invited to do so by a Hologic Recruiter. All resumes must be sent to the Hologic Recruiter under these terms or they will not be considered.
As part of our commitment to a fair and accurate evaluation of each candidate's qualifications, we require all applicants to refrain from using AI tools, such as generative AI or automated writing assistance, during any stage of the interview process. Responses influenced by AI may result in disqualification. We appreciate your understanding and cooperation in ensuring a transparent and equitable selection process.
Hologic, Inc. is proud to be an Equal Opportunity Employer inclusive of disability and veterans.
LI-#DS1
See All 21 Systems Development Engineer Jobs in Delaware
Find roles in Delaware that match your experience and apply in just a few clicks.
Find JobsSystems Development Engineer Jobs by City in Delaware
Where Delaware roles are concentrated, by current openings.
Systems Development Engineer Job Market in Delaware
A snapshot from current Delaware openings, updated as new roles post.
Who's Hiring
- KBR2

- Hologic2

- TA Instruments2

- The Bancorp2

- ADP1

Top Industries Hiring
- Medical Devices4
- Technology & Software3
- Manufacturing1
- Banking & Financial Services1
- Biotechnology & Pharmaceuticals1
What Delaware Employers Look For
The qualifications that appear most often in systems development engineer jobs across Delaware.
- Bachelor's degree in computer science, software engineering, or a closely related technical field
- Proficiency in at least one scripting or systems language such as Python, Go, or Java
- Experience designing and maintaining CI/CD pipelines and infrastructure automation tools
- Hands-on background with cloud platforms such as AWS, Azure, or Google Cloud
- Familiarity with containerization and orchestration technologies including Docker and Kubernetes
- Strong understanding of distributed systems architecture and reliability engineering principles
Systems Development Engineer Jobs in Delaware: Frequently Asked Questions
How do you become a systems development engineer in Delaware?
The standard path into systems development engineering in Delaware begins with a bachelor's degree in computer science, software engineering, or a related field. Delaware does not require a state-issued license for this role. Most employers, particularly in Wilmington's financial sector and Newark's research and defense corridor, also expect demonstrated experience with cloud infrastructure and automation through projects, internships, or prior engineering roles before making an offer at the systems engineer level.
How much do systems development engineers make in Delaware?
Systems development engineers in Delaware earn a median of about $133,020 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $96,620 for the lowest 10% to over $174,390 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire systems development engineers in Delaware?
Employers hiring systems development engineers in Delaware right now include KBR, Hologic, and TA Instruments, based on current listings on Migrate Mate as of July 2026. Delaware's concentration of Fortune 500 financial headquarters and life sciences operations in the Wilmington and Newark areas means that many of these employers are looking for engineers who can support large-scale, regulated technology environments.
Which Delaware cities have the most systems development engineer jobs?
Wilmington, Newark, and New Castle account for the largest share of systems development engineer openings in Delaware. Wilmington drives volume through its dense cluster of major financial institutions and corporate headquarters, while Newark benefits from the University of Delaware's research partnerships and proximity to defense and life sciences employers, and Dover reflects state government and regional enterprise technology needs.
Are there remote systems development engineer jobs in Delaware?
Yes, and more than most fields. About 55% of systems development engineer openings tied to Delaware are remote or hybrid as of July 2026, reflecting how naturally the role lends itself to distributed work. The aspects most likely to be fully remote are infrastructure automation, platform tooling, and CI/CD work, while roles tied to on-premise systems or regulated financial environments more often require at least partial on-site presence.
How can I get hired as a systems development engineer in Delaware with little or no experience?
The most realistic entry point is an associate systems engineer or DevOps engineer role, which major Delaware employers in the financial and life sciences sectors use as a pipeline for systems talent. Candidates without direct experience do well to come in from adjacent roles such as systems administrator, IT operations analyst, or software developer. Building a portfolio of automation scripts, cloud deployments, or open-source CI/CD contributions strengthens applications considerably, as does completing a cloud certification recognized by Delaware's major enterprise employers.
Where can I find and apply to systems development engineer jobs in Delaware?
You can find and apply to systems development engineer jobs in Delaware on Migrate Mate, which lists current Delaware openings across industries and experience levels. Find roles that fit your background and apply directly to the employers posting them.
See All 21 Systems Development Engineer Jobs in Delaware
Find roles in Delaware that match your experience and apply in just a few clicks.
Find Jobs