STEM OPT Senior Researcher Jobs
Senior Researcher roles in R&D, academia, and biotech are strong fits for STEM OPT students with degrees in life sciences, computer science, engineering, or related fields. Your 24-month STEM OPT extension applies as long as your employer is enrolled in E-Verify and your role directly applies your STEM degree.
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Position Summary
The Buck Institute for Research on Aging is seeking a full-time Bioinformatics and Data Scientist or Postdoctoral Researcher to join a collaborative research team focused on aging, multi-omics, computational biology, and translational data science. This position offers a unique opportunity to work in an academic research environment with a close-knit, interdisciplinary team while collaborating with leading experts in aging biology, bioinformatics, clinical research, and computational science. The successful candidate will contribute to a five-year government-funded project focused on advancing computational and multi-omics approaches to better understand human aging, biological resilience, and healthspan. This role will support broader nationwide efforts to develop data-driven approaches that may ultimately improve how aging and age-related disease risk are measured, modeled, and addressed. The ideal candidate will have strong experience in bioinformatics, statistics, computational biology, human omics data analysis, and scientific communication. The position is well suited for an independent, highly motivated scientist who enjoys working across disciplines and contributing to both discovery-driven and translational research.
Key Responsibilities
2. Analyze, curate, and manage research data
- Perform bioinformatics and data science analyses. The successful candidate will analyze diverse biological and clinical datasets, including but not limited to:
- Proteomics
- Metabolomics
- Methylomics
- Survey data
- Integrative multi-omics datasets
- Human biological aging and omics-clock data
- Drug repurposing analyses
- Enrichment and pathway analyses
- Dimensionality reduction and clustering
- Classification methods, including random forests and support vector machines
- Neural network-based approaches
- Simple and multiple linear regression
- Parametric and non-parametric statistical analyses
Responsibilities will include:
- Curating, organizing, and preparing data for analysis and upload to central repositories
- Supporting data harmonization across projects, cohorts, and collaborators in accordance with data use agreements
- Reviewing and improving standard operating procedures for data transfer, quality control, and management
- Coordinating with internal and external teams to ensure timely collection, transfer, and analysis of data
- Attending project meetings and contributing to improvements in data workflows, systems, and documentation
- Ensuring data quality, reproducibility, and compliance with project requirements
3. Collaborate with scientific and administrative teams
The candidate will work closely with staff members, research scientists, computational biologists, principal investigators, and external collaborators. Responsibilities may include:
- Contributing to grant applications, progress reports, and scientific proposals
- Supporting manuscript preparation and journal article writing
- Creating publication-quality figures, tables, and data visualizations
- Presenting analyses and findings to interdisciplinary research teams
- Helping translate complex computational results into clear biological and scientific interpretations
Qualifications
Required Education and Experience
- Strong background in both human biology and bioinformatics
- PhD in Computational Biology, Bioinformatics, Data Science, Biostatistics, Systems Biology, Computer Science, or a related field
- Minimum of 2 years of professional experience in a biological, biomedical, or computational research environment
- Strong proficiency in R, Python, and Bash scripting
- Demonstrated experience analyzing biological or biomedical datasets
- Experience developing, implementing, and running bioinformatics workflows
Required Skills
- Strong analytical, mathematical, and creative problem-solving skills
- Excellent written and oral communication skills
- Ability to work both independently and collaboratively in a team-based research environment
- Strong organizational skills and attention to detail
- Ability to prioritize and execute multiple tasks across concurrent projects
- Experience with reproducible data analysis practices and documentation
- Ability to communicate technical results to both computational and non-computational audiences
- Interest in applying large language models, agentic AI, or related computational tools to biomedical research workflows
Preferred Qualifications
- Experience with FDA approval process
- Experience with building apps
Compensation And Benefits
- Salary range: $80,000–$85,000, commensurate with experience
- Full-time, onsite position
- Exciting, collaborative work environment at the forefront of aging research
- Opportunity to work with state-of-the-art technologies and interdisciplinary scientific teams
- Generous benefits package, including:
- Health insurance
- Paid parental leave
- Generous paid time off
- 401(k) with 5% employer match
- Work visa sponsorship available for qualified candidates
About The Buck Institute
Our success will ultimately change healthcare. At the Buck Institute for Research on Aging, we aim to end the threat of age-related diseases for this and future generations by bringing together the most capable and passionate scientists from a broad range of disciplines to identify and impede the ways in which we age. The Buck is an independent, nonprofit institution located in Marin County, California, with the goal of increasing human healthspan, or the healthy years of life. Globally recognized as a pioneer and leader in efforts to target aging — the number one risk factor for diseases including Alzheimer’s disease, Parkinson’s disease, cancer, macular degeneration, heart disease, and diabetes — the Buck seeks to help people live better longer. We are an equal opportunity employer and strive to create an atmosphere where diversity of identity, experience, and background are welcomed, valued, and supported. Candidates who contribute to this diversity are strongly encouraged to apply.
To Apply
Interested candidates should click the Apply button to complete the online application. Please upload both:
- Your CV
- A brief statement of research interests, including the names and contact information for three references
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Get Access To All JobsTips for Finding STEM OPT Authorization in Senior Researcher
Verify your CIP code before applying
Check that your degree's Classification of Instructional Programs code appears on the STEM OPT eligible fields list. Mismatches between your CIP code and your degree title are a common reason DSOs can't authorize the extension.
Confirm E-Verify enrollment before accepting offers
Ask recruiters directly whether the hiring entity, not just the parent company, is enrolled in E-Verify. Research divisions and subsidiary labs sometimes operate under separate EINs that aren't covered by a parent organization's enrollment.
Align your I-983 training plan to the role
Your training plan must map your Senior Researcher duties to specific learning objectives tied to your STEM degree. Vague job descriptions get pushed back by DSOs, so request a detailed position description from your hiring manager before submitting.
Target R&D-heavy employers with consistent OPT hiring
Use Migrate Mate to filter Senior Researcher postings by employers with documented STEM OPT hiring history. Government labs, pharmaceutical companies, and university-affiliated research centers file consistently and have established onboarding processes for OPT students.
Benchmark your offer against OFLC Wage Search data
Look up the prevailing wage for your SOC code and work location using the OFLC Wage Search before negotiating. Senior Researcher roles span multiple wage levels depending on supervision and complexity, and your offer affects future H-1B visa LCA compliance.
File your extension request 90 days before OPT expires
USCIS requires your STEM OPT extension application to be submitted no more than 90 days before your initial OPT end date. Missing this window means a gap in work authorization that can't be retroactively fixed, even with an approved extension.
Frequently Asked Questions
Does a Senior Researcher role qualify for the STEM OPT extension?
Yes, if your STEM degree directly relates to the research work you'll be performing. Senior Researcher positions in fields like computational biology, materials science, or data science typically qualify. Your DSO will confirm eligibility based on your specific CIP code and the job duties described in your I-983 training plan, not just your job title.
What E-Verify requirement applies to STEM OPT employers hiring researchers?
Your employer must be enrolled in E-Verify at the specific site where you'll work. For Senior Researcher roles at institutions with multiple campuses or research divisions, the enrolling entity must match your actual worksite. You can confirm enrollment by asking HR for the employer's E-Verify company ID or by requesting written confirmation before your start date.
How should the I-983 training plan reflect Senior Researcher responsibilities?
Your I-983 must tie each primary job duty to a specific learning objective connected to your STEM degree. For Senior Researcher roles, this means detailing how activities like experimental design, data analysis, or literature synthesis develop skills within your degree field. Generic descriptions like 'conduct research' are insufficient. Work with your supervisor to draft duty-specific language before submitting to your DSO.
What happens to my STEM OPT if my employer loses E-Verify enrollment?
If your employer's E-Verify enrollment lapses after your extension begins, you're required to report the change to your DSO within five days and either secure re-enrollment or find a new qualifying employer. Continued employment without a current E-Verify enrollment violates STEM OPT terms and can jeopardize your status, even if the gap is brief.
Where can I find Senior Researcher jobs posted by E-Verify enrolled employers?
Migrate Mate filters Senior Researcher postings specifically for STEM OPT students, surfacing roles at employers already enrolled in E-Verify. This saves you the step of manually verifying each employer's enrollment status before applying. You can search by research area, degree field, and work location to narrow results to positions that fit your STEM OPT eligibility.