Senior Level System Administrator Jobs
Senior level system administrator jobs put experienced professionals in charge of infrastructure strategy, system reliability, and the engineering teams or cross-functional projects that keep enterprise environments running. Openings are concentrated across on-site, remote, and hybrid settings in Technology & Software, Consulting & Professional Services, and Aerospace & Defense, with employers like Columbia Technology Partners, All Points Logistics, and JT4 hiring at this level now.
Find JobsOverview
Showing 5 of 71+ Senior Level System Administrator jobs
About USDM
USDM Life Sciences is a premier consulting company with 20+ years of experience assisting heavily regulated biotech, medical device, and pharmaceutical companies with their GxP technologies to accelerate growth. Our deep domain knowledge and technology expertise in life sciences business processes are what set us apart. From strategy to implementation and adoption, we have delivered thousands of GxP projects globally.
As part of the USDM team, you have the opportunity to work with cutting-edge technologies through our many partnerships with companies like Microsoft, Google, Oracle, DocuSign, Box, and many more. From molecule to market, you will help connect technology, people, and data in new ways to generate real-time insights to improve business outcomes for USDM’s clients. Are you ready to make an impact and drive real digital transformation in life sciences?
Founded in Santa Barbara in 1999, USDM has grown to a progressive, global company with 300+ remote employees and offices throughout the US, Canada, and Germany.
Nature and Scope of Job
We are seeking an experienced Application System Administrator to support manufacturing, laboratory, and automation systems at a regulated biotech/pharma site. The contractor will ensure all supported systems remain reliable, secure, compliant, and inspection-ready in accordance with GxP standards and site procedures. This role works cross-functionally with Automation Engineering, IT, Quality, and Operations teams to maintain day-to-day system operations and support continuous improvement.
Primary Responsibilities
- Administer and maintain OT/automation applications including DeltaV, Rockwell FactoryTalk, PI Historian, LabX, Unicorn, Sartocheck 5, ThinManager, Metasys, and Nova Biomass
- Manage user accounts, roles, and permissions; support periodic access reviews and resolve access-related issues
- Monitor system performance and availability; respond to and troubleshoot incidents and escalate critical issues per site procedures
- Support root cause investigations, deviations, and CAPA activities
- Execute system changes through approved change control processes and maintain configuration documentation
- Ensure backup processes are operational, monitored, and validated; support disaster recovery testing
- Perform periodic system health checks including audit trail reviews, antivirus logs, and user account reviews
- Maintain accurate, complete, and audit-ready system documentation including SOPs, work instructions, and activity logs
- Support regulatory inspections and audits as required
Additional Responsibilities
- Performs other related duties and assignments as required
Qualifications
- Experience administering computerized systems in a GxP-regulated environment
- Hands-on knowledge of DCS/SCADA systems (DeltaV, Rockwell FactoryTalk), Historian platforms (PI), and/or laboratory systems (LabX, Unicorn, Sartocheck 5)
- Understanding of data integrity principles (ALCOA+) and Computerized System Validation (CSV)
- Familiarity with change control and CAPA processes, including TrackWise or similar quality management systems
- Ability to maintain detailed documentation and operate effectively in an audit-ready environment
Education & Certifications
- Bachelor’s degree in Computer Science or Information Systems or related field.
- Master’s Degree preferred
Working Conditions
The working conditions described here are representative of those that must be met by an employee to successfully perform the essential responsibilities and functions of the job and are not meant to be all-inclusive. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential responsibilities and functions of the job.
Unless reasonable accommodations can be made, while performing this job the staff member shall:
- Prolonged periods of sitting or standing at a desk and working on a computer in an environmentally controlled home office environment.
- Operate other office productivity machinery, such as a calculator, scanner, or printer.
- Frequently communicate with stakeholders via telephone, email, or instant message. Must be able to exchange accurate information in these situations.
Equal Opportunity Statement
USDM Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
Disclaimer
This job description is intended to describe the general nature and the level of the work being performed by the people assigned to this position. It is not intended to include every job duty and responsibility specific to the position. USDM Life Sciences reserves the right to amend and change responsibilities to meet business and organizational needs as necessary.
Compensation
Salary/Hourly Rate Range (W2): USD 65.00 - 80.00
The base salary/hourly rate range represents the anticipated low and high end of the USDM’s compensation range for this position. Actual salaries/hourly rates will vary and will be based on various factors, such as the candidate’s qualifications, skills, competencies, and proficiency for the role. The compensation described above is subject to change and could be higher or lower than the range described based on market survey data or budget.
Full-time employees are eligible for health, vision, and dental insurance, life insurance, short and long-term disability, hospital indemnity, accident, and critical care coverage.
Both full and part-time employees, who are at least 21 years of age, are eligible to participate in USDM's 401k plan. Full and part-time employees may be eligible for paid time off.
All employees are eligible for USDM's rewards and recognition program.
For more details about our benefits, visit us here: https://usdm.com/careers
About USDM
USDM Life Sciences is a premier consulting company with 20+ years of experience assisting heavily regulated biotech, medical device, and pharmaceutical companies with their GxP technologies to accelerate growth. Our deep domain knowledge and technology expertise in life sciences business processes are what set us apart. From strategy to implementation and adoption, we have delivered thousands of GxP projects globally.
As part of the USDM team, you have the opportunity to work with cutting-edge technologies through our many partnerships with companies like Microsoft, Google, Oracle, DocuSign, Box, and many more. From molecule to market, you will help connect technology, people, and data in new ways to generate real-time insights to improve business outcomes for USDM’s clients. Are you ready to make an impact and drive real digital transformation in life sciences?
Founded in Santa Barbara in 1999, USDM has grown to a progressive, global company with 300+ remote employees and offices throughout the US, Canada, and Germany.
Nature and Scope of Job
We are seeking an experienced Application System Administrator to support manufacturing, laboratory, and automation systems at a regulated biotech/pharma site. The contractor will ensure all supported systems remain reliable, secure, compliant, and inspection-ready in accordance with GxP standards and site procedures. This role works cross-functionally with Automation Engineering, IT, Quality, and Operations teams to maintain day-to-day system operations and support continuous improvement.
Primary Responsibilities
- Administer and maintain OT/automation applications including DeltaV, Rockwell FactoryTalk, PI Historian, LabX, Unicorn, Sartocheck 5, ThinManager, Metasys, and Nova Biomass
- Manage user accounts, roles, and permissions; support periodic access reviews and resolve access-related issues
- Monitor system performance and availability; respond to and troubleshoot incidents and escalate critical issues per site procedures
- Support root cause investigations, deviations, and CAPA activities
- Execute system changes through approved change control processes and maintain configuration documentation
- Ensure backup processes are operational, monitored, and validated; support disaster recovery testing
- Perform periodic system health checks including audit trail reviews, antivirus logs, and user account reviews
- Maintain accurate, complete, and audit-ready system documentation including SOPs, work instructions, and activity logs
- Support regulatory inspections and audits as required
Additional Responsibilities
- Performs other related duties and assignments as required
Qualifications
- Experience administering computerized systems in a GxP-regulated environment
- Hands-on knowledge of DCS/SCADA systems (DeltaV, Rockwell FactoryTalk), Historian platforms (PI), and/or laboratory systems (LabX, Unicorn, Sartocheck 5)
- Understanding of data integrity principles (ALCOA+) and Computerized System Validation (CSV)
- Familiarity with change control and CAPA processes, including TrackWise or similar quality management systems
- Ability to maintain detailed documentation and operate effectively in an audit-ready environment
Education & Certifications
- Bachelor’s degree in Computer Science or Information Systems or related field.
- Master’s Degree preferred
Working Conditions
The working conditions described here are representative of those that must be met by an employee to successfully perform the essential responsibilities and functions of the job and are not meant to be all-inclusive. Reasonable accommodation may be made to enable individuals with disabilities to perform the essential responsibilities and functions of the job.
Unless reasonable accommodations can be made, while performing this job the staff member shall:
- Prolonged periods of sitting or standing at a desk and working on a computer in an environmentally controlled home office environment.
- Operate other office productivity machinery, such as a calculator, scanner, or printer.
- Frequently communicate with stakeholders via telephone, email, or instant message. Must be able to exchange accurate information in these situations.
Equal Opportunity Statement
USDM Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, or status as a protected veteran.
Disclaimer
This job description is intended to describe the general nature and the level of the work being performed by the people assigned to this position. It is not intended to include every job duty and responsibility specific to the position. USDM Life Sciences reserves the right to amend and change responsibilities to meet business and organizational needs as necessary.
Compensation
Salary/Hourly Rate Range (W2): USD 65.00 - 80.00
The base salary/hourly rate range represents the anticipated low and high end of the USDM’s compensation range for this position. Actual salaries/hourly rates will vary and will be based on various factors, such as the candidate’s qualifications, skills, competencies, and proficiency for the role. The compensation described above is subject to change and could be higher or lower than the range described based on market survey data or budget.
Full-time employees are eligible for health, vision, and dental insurance, life insurance, short and long-term disability, hospital indemnity, accident, and critical care coverage.
Both full and part-time employees, who are at least 21 years of age, are eligible to participate in USDM's 401k plan. Full and part-time employees may be eligible for paid time off.
All employees are eligible for USDM's rewards and recognition program.
For more details about our benefits, visit us here: https://usdm.com/careers
See All 71 Senior Level System Administrator Jobs
Find roles that match your experience and apply in just a few clicks.
Find JobsSenior Level System Administrator Job Market
Who's Hiring
- Columbia Technology Partners5
- All Points Logistics4
- JT43
- Maximus3
- Everforth ECS3E
Top Industries Hiring
- Technology & Software11
- Consulting & Professional Services9
- Aerospace & Defense4
- Electronics & Hardware4
- Transportation & Logistics4
Senior Level System Administrator Jobs: Frequently Asked Questions
How do I get a senior level system administrator job?
Focus on demonstrating ownership rather than task execution. Employers at this level want candidates who have architected solutions, led migrations or upgrades end to end, and mentored junior staff. Highlight cross-team projects where your decisions shaped outcomes, certifications like RHCE, MCSE, or AWS SysOps, and experience with large-scale or highly available environments. A portfolio of infrastructure improvements you initiated carries significant weight.
Which companies hire senior level system administrators?
Companies hiring senior level system administrators right now include Columbia Technology Partners, All Points Logistics, and JT4, based on current listings on Migrate Mate as of July 2026. Hiring at this level tends to come from large enterprises, government contractors, healthcare systems, and technology firms that rely on complex, always-on infrastructure and need experienced professionals to own it.
Are there remote senior level system administrator jobs?
Yes, though availability varies by employer and infrastructure requirements. About 13% of senior level system administrator openings are remote or hybrid as of July 2026, reflecting demand from organizations comfortable with distributed IT leadership. Roles tied to on-premises hardware or regulated environments often require at least partial on-site presence, while cloud-heavy environments offer more flexibility.
What makes a system administrator role senior level?
Senior level system administrator roles are defined by scope, accountability, and leadership. These positions own infrastructure decisions rather than implementing someone else's plan, drive architecture improvements, set standards across teams, and are responsible for uptime and security at an organizational level. Mentoring junior and mid-level administrators and collaborating directly with engineering and security leadership are also core expectations at this stage.
Which industries hire the most senior level system administrators?
Senior Level system administrator roles concentrate in Technology & Software, Consulting & Professional Services, and Aerospace & Defense, based on current listings on Migrate Mate as of July 2026. These sectors tend to operate large, regulated, or mission-critical environments where experienced system ownership, compliance requirements, and infrastructure scale demand professionals who can lead rather than just maintain.