Executive Director of Operations Visa Sponsorship Jobs in California
Executive director of operations visa sponsorship jobs in California are concentrated in San Francisco, Los Angeles, and San Diego, where technology, life sciences, and entertainment companies regularly sponsor senior operations leaders. Major employers include Salesforce, Kaiser Permanente, and Northrop Grumman. International candidates with advanced degrees and deep operations experience pursue H-1B visa and EB-2 pathways for these roles.
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Get Access To All JobsINTRODUCTION
Fate Therapeutics is seeking an Executive Director, Clinical Operations to contribute to the strategy and lead execution of our global clinical operations across multiple cell therapy franchises. In this senior leadership role, you will drive the planning and delivery of studies built on a differentiated, off-the-shelf platform designed for broad patient access. Partnering closely with the executive team, clinical leadership, and cross-functional colleagues, you will shape portfolio priorities, ensure operational excellence in site start-up, enrollment, and data quality, and own the timelines and budgets that bring our pipeline to patients. If you are a strategic, hands-on leader who thrives on building high-performing teams and scalable processes, this is an opportunity to make a meaningful impact on the future of cell therapy in autoimmune disease.
Responsibilities
- Lead and drive successful execution of the company’s clinical operation strategies through establishing consistent and deliverable operational plans across multiple cell therapy franchises.
- Establish study planning models, oversee efficient site start-up across multiple countries and drive patient recruitment as part of a unique outpatient administration and on-demand available cell therapy platform for broad patient access.
- Partner with executive team to plan and drive corporate clinical initiatives, and to establish delivery strategies, portfolio priorities, and progress metrics.
- Partner with larger clinical organization to provide operational input into clinical protocol design, study endpoints, enrollment strategy, and trial timelines.
- Provide strategic oversight of global cell therapy studies to deliver on timelines and cost allocations; own variable and headcount costs for the assigned portfolio, including forecasting, resource allocation assumptions, change order review, and cost containment, in partnership with Finance.
- Develop and oversee patient enrollment, data and timeline completion risk mitigation plans, patient data quality, and completion timelines.
- Maintain integration and alignment of Clinical Operations with key cross-functional departments including Clinical Outsourcing, Program Management, R&D, Manufacturing, Biometrics, Regulatory, QA, Safety/Pharmacovigilance, Legal, Finance, and external partners to translate portfolio strategy into executable plans; lead partnerships with external partners, vendors and CROs.
- Establish performance metrics, dashboards and forecasting models (enrollment, site activation, protocol deviations, query rates, cycle times) to drive accountability; oversee site selection, feasibility, activation, and engagement, including patient recruitment and retention.
- Build relationships with key opinion leaders, investigators, and sites to support innovation into clinical operations practice; travel to sites and represent the company at investigator meetings, advisory boards, conferences, and patient advocacy events; contribute to corporate planning, investor updates, and partnering or due diligence activities as needed.
- Lead development and continuous improvement of scalable SOPs, processes, and tools, ensuring adherence to GCP and applicable regulations.
- Build a culture of ownership, transparency, continuous improvement, and shape organizational design and hiring to match pipeline growth, balancing internal headcount with flexible resources.
BASIC QUALIFICATIONS
- BS/BA or advanced degree with a minimum of 14 years of pharmaceutical and/or biotech experience in a clinical drug development setting.
- Strong leadership competencies and influencing skills with senior leaders and cross functional leaders.
- Extensive experience with clinical operations line management, performance management and staff coaching.
- Proven leadership of clinical operations functions and execution of clinical trials including successful study start-up, site selection, patient recruitment, and relationship building with investigators and CROs; intimate knowledge of study site selection and site start up in the oncology or autoimmunity space.
- Experience in clinical resource allocation and budget forecasting.
- Management experience including outsourcing to third-party organizations, e.g., CROs.
- Expert knowledge of FDA and GCP regulations and guidelines.
- Experience in the development of protocols, SOPs, clinical study reports, INDs, NDAs and other clinical, regulatory and safety documents required.
- Effective oral and written communication skills to influence, inform and guide the clinical operational team.
- Strong project management skills.
- Proven team building skills and ability to foster partnerships across projects and multidisciplinary teams.
- Experience in cell-based therapies is highly preferred.
- Excellent organizational, communication and people management skills required.
WORKING CONDITIONS & PHYSICAL REQUIREMENTS
- Travel may be required (up to 30%).
- Subject to extended periods of sitting and standing, vision to monitor, and moderate noise levels.
COMPENSATION
- The salary offer will be based on a variety of factors, including level, experience, qualifications, internal equity, and location.
- Fate offers a competitive employment package that includes an annual bonus, equity, and a generous benefits package.
- The anticipated salary range for this role is $280,000 - $300,000.
The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time.
Equal Employment Opportunity
Fate Therapeutics, Inc. is an equal opportunity employer. We value diversity and are committed to creating an inclusive environment for all employees.
Privacy Notice
To learn about how Fate collects and uses job application information, please visit Fate's online Privacy Notice.
About Fate Therapeutics, Inc.
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to bringing a pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients. Using its proprietary iPSC product platform, the Company has established a leadership position in creating multiplexed-engineered master iPSC lines and in the manufacture and clinical development of off-the-shelf, iPSC-derived cell products. The Company’s pipeline includes iPSC-derived T-cell and natural killer (NK) cell product candidates, which are selectively designed, incorporate novel synthetic controls of cell function, and are intended to deliver multiple therapeutic mechanisms to patients. Fate Therapeutics is headquartered in San Diego, CA.
⚠️ Recruitment Fraud Alert
Recently, we have been made aware of unauthorized individuals falsely presenting themselves as Fate Therapeutics employees or recruiters as part of online scams or phishing attempts. Impersonators may use the Fate Therapeutics name and logo, as well as employee names and job titles, to gain a job seeker’s personal or banking information or to request payment as a condition of being considered for a position at the company. Fate Therapeutics and its employees are not involved in these scams. Here are a few things to be aware of to help identify recruitment fraud:
- Our Talent Acquisition team only corresponds from our @fatetherapeutics.com domain.
- At no stage in our hiring process will we require payment or ask you to make deposits in your bank account.
- We will only ask for personal information when applying for a position via our Careers page or thereafter.
- At no stage during our hiring process will we ask you to click a link to begin a one-way video interview.
- We do not use Google Hangouts, WhatsApp, or other third-party messaging platforms to recruit candidates or conduct interviews.
Please exercise caution. If something feels off about your interactions, we encourage you to contact us at [email protected] to confirm the authenticity of the message. Your security is important to us, and we appreciate your vigilance. We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
INTRODUCTION
Fate Therapeutics is seeking an Executive Director, Clinical Operations to contribute to the strategy and lead execution of our global clinical operations across multiple cell therapy franchises. In this senior leadership role, you will drive the planning and delivery of studies built on a differentiated, off-the-shelf platform designed for broad patient access. Partnering closely with the executive team, clinical leadership, and cross-functional colleagues, you will shape portfolio priorities, ensure operational excellence in site start-up, enrollment, and data quality, and own the timelines and budgets that bring our pipeline to patients. If you are a strategic, hands-on leader who thrives on building high-performing teams and scalable processes, this is an opportunity to make a meaningful impact on the future of cell therapy in autoimmune disease.
Responsibilities
- Lead and drive successful execution of the company’s clinical operation strategies through establishing consistent and deliverable operational plans across multiple cell therapy franchises.
- Establish study planning models, oversee efficient site start-up across multiple countries and drive patient recruitment as part of a unique outpatient administration and on-demand available cell therapy platform for broad patient access.
- Partner with executive team to plan and drive corporate clinical initiatives, and to establish delivery strategies, portfolio priorities, and progress metrics.
- Partner with larger clinical organization to provide operational input into clinical protocol design, study endpoints, enrollment strategy, and trial timelines.
- Provide strategic oversight of global cell therapy studies to deliver on timelines and cost allocations; own variable and headcount costs for the assigned portfolio, including forecasting, resource allocation assumptions, change order review, and cost containment, in partnership with Finance.
- Develop and oversee patient enrollment, data and timeline completion risk mitigation plans, patient data quality, and completion timelines.
- Maintain integration and alignment of Clinical Operations with key cross-functional departments including Clinical Outsourcing, Program Management, R&D, Manufacturing, Biometrics, Regulatory, QA, Safety/Pharmacovigilance, Legal, Finance, and external partners to translate portfolio strategy into executable plans; lead partnerships with external partners, vendors and CROs.
- Establish performance metrics, dashboards and forecasting models (enrollment, site activation, protocol deviations, query rates, cycle times) to drive accountability; oversee site selection, feasibility, activation, and engagement, including patient recruitment and retention.
- Build relationships with key opinion leaders, investigators, and sites to support innovation into clinical operations practice; travel to sites and represent the company at investigator meetings, advisory boards, conferences, and patient advocacy events; contribute to corporate planning, investor updates, and partnering or due diligence activities as needed.
- Lead development and continuous improvement of scalable SOPs, processes, and tools, ensuring adherence to GCP and applicable regulations.
- Build a culture of ownership, transparency, continuous improvement, and shape organizational design and hiring to match pipeline growth, balancing internal headcount with flexible resources.
BASIC QUALIFICATIONS
- BS/BA or advanced degree with a minimum of 14 years of pharmaceutical and/or biotech experience in a clinical drug development setting.
- Strong leadership competencies and influencing skills with senior leaders and cross functional leaders.
- Extensive experience with clinical operations line management, performance management and staff coaching.
- Proven leadership of clinical operations functions and execution of clinical trials including successful study start-up, site selection, patient recruitment, and relationship building with investigators and CROs; intimate knowledge of study site selection and site start up in the oncology or autoimmunity space.
- Experience in clinical resource allocation and budget forecasting.
- Management experience including outsourcing to third-party organizations, e.g., CROs.
- Expert knowledge of FDA and GCP regulations and guidelines.
- Experience in the development of protocols, SOPs, clinical study reports, INDs, NDAs and other clinical, regulatory and safety documents required.
- Effective oral and written communication skills to influence, inform and guide the clinical operational team.
- Strong project management skills.
- Proven team building skills and ability to foster partnerships across projects and multidisciplinary teams.
- Experience in cell-based therapies is highly preferred.
- Excellent organizational, communication and people management skills required.
WORKING CONDITIONS & PHYSICAL REQUIREMENTS
- Travel may be required (up to 30%).
- Subject to extended periods of sitting and standing, vision to monitor, and moderate noise levels.
COMPENSATION
- The salary offer will be based on a variety of factors, including level, experience, qualifications, internal equity, and location.
- Fate offers a competitive employment package that includes an annual bonus, equity, and a generous benefits package.
- The anticipated salary range for this role is $280,000 - $300,000.
The preceding job description indicates the general nature and level of work performed by employees within this classification. Additional and incidental duties related to the primary duties may be required from time to time.
Equal Employment Opportunity
Fate Therapeutics, Inc. is an equal opportunity employer. We value diversity and are committed to creating an inclusive environment for all employees.
Privacy Notice
To learn about how Fate collects and uses job application information, please visit Fate's online Privacy Notice.
About Fate Therapeutics, Inc.
Fate Therapeutics is a clinical-stage biopharmaceutical company dedicated to bringing a pipeline of induced pluripotent stem cell (iPSC)-derived cellular immunotherapies to patients. Using its proprietary iPSC product platform, the Company has established a leadership position in creating multiplexed-engineered master iPSC lines and in the manufacture and clinical development of off-the-shelf, iPSC-derived cell products. The Company’s pipeline includes iPSC-derived T-cell and natural killer (NK) cell product candidates, which are selectively designed, incorporate novel synthetic controls of cell function, and are intended to deliver multiple therapeutic mechanisms to patients. Fate Therapeutics is headquartered in San Diego, CA.
⚠️ Recruitment Fraud Alert
Recently, we have been made aware of unauthorized individuals falsely presenting themselves as Fate Therapeutics employees or recruiters as part of online scams or phishing attempts. Impersonators may use the Fate Therapeutics name and logo, as well as employee names and job titles, to gain a job seeker’s personal or banking information or to request payment as a condition of being considered for a position at the company. Fate Therapeutics and its employees are not involved in these scams. Here are a few things to be aware of to help identify recruitment fraud:
- Our Talent Acquisition team only corresponds from our @fatetherapeutics.com domain.
- At no stage in our hiring process will we require payment or ask you to make deposits in your bank account.
- We will only ask for personal information when applying for a position via our Careers page or thereafter.
- At no stage during our hiring process will we ask you to click a link to begin a one-way video interview.
- We do not use Google Hangouts, WhatsApp, or other third-party messaging platforms to recruit candidates or conduct interviews.
Please exercise caution. If something feels off about your interactions, we encourage you to contact us at [email protected] to confirm the authenticity of the message. Your security is important to us, and we appreciate your vigilance. We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.
Executive Director of Operations Job Roles in California
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Search Executive Director of Operations Jobs in CaliforniaExecutive Director of Operations Jobs in California: Frequently Asked Questions
Which companies in California sponsor visas for executive director of operations roles?
Large California employers with active H-1B and green card sponsorship histories for senior operations roles include Salesforce, Apple, Google, Kaiser Permanente, Genentech, and Northrop Grumman. Technology companies in the San Francisco Bay Area and life sciences firms in San Diego and South San Francisco tend to have dedicated immigration support infrastructure for executive-level operational hires.
Which visa types realistically fit executive director of operations roles in California?
The H-1B is the most common pathway, as the role qualifies as a specialty occupation requiring at least a bachelor's degree in business administration, operations management, or a related field. The employer files a Labor Condition Application and I-129 petition with USCIS. The O-1A applies if you have extraordinary achievement in your field. EB-2 and EB-3 employment-based green cards are long-term options requiring PERM labor certification for most cases.
Which cities in California have the most executive director of operations visa sponsorship jobs?
San Francisco and Silicon Valley lead due to the concentration of technology and venture-backed companies with global workforces. Los Angeles follows, driven by entertainment, aerospace, and consumer goods headquarters. San Diego is a strong market for life sciences and defense operations roles. Sacramento has a smaller but growing presence through state-adjacent agencies and healthcare systems that sponsor senior operations professionals.
How to find executive director of operations visa sponsorship jobs in California?
Migrate Mate lists California employers with verified sponsorship histories for senior operations roles, letting you focus your search on companies that have actively filed for similar positions. Because executive director of operations roles require employer-initiated sponsorship, targeting companies with a demonstrated track record is more efficient than applying broadly. Migrate Mate narrows that pool by role and location across California's major hiring centers.
Are there any California-specific factors that affect visa sponsorship for executive director of operations roles?
California's large multinational employer base means more companies have established immigration programs than in most other states. The state's university system, including UC Berkeley, UCLA, and USC, produces graduate-level operations talent that some employers initially hire on OPT before transitioning to H-1B sponsorship. California also has a high concentration of EB-1C multinational manager petitions, which can apply to operations executives transferring from overseas offices.
What is the prevailing wage for sponsored executive director of operations jobs in California?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.