Machine Learning Engineer Visa Sponsorship Jobs in Missouri
Missouri's machine learning engineer market is anchored by employers in St. Louis and Kansas City, including major players in healthcare IT, financial services, and defense contracting such as Express Scripts, Cerner, and Boeing. Companies across these sectors actively hire for ML roles and have established records of sponsoring H-1B and other work visas for qualified international candidates.
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INTRODUCTION
We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time.
At CVS Health, our purpose is to deliver better health outcomes by meeting consumers where they are—through local care, digital experiences, and a nationwide team committed to quality, safety, and affordability.
Our Solutions Engineering and Infrastructure organization is building an enterprise AI/ML capability that delivers reliable, responsible, and secure AI-powered platforms and solutions at Fortune 5 scale, and this role is foundational to help us develop that capability.
This is a senior individual-contributor role, focused on identifying evaluating and documenting high-value use cases, designing and prototyping AI-powered solutions, and evolving them into secure, resilient, enterprise-ready products and platform components.
ROLE AND RESPONSIBILITIES
Key Responsibilities:
AI Solution Design & Prototyping
- Partner with stakeholders to identify, evaluate, document, and shape GenAI use cases (copilots, automation, decision support, and insight generation) with clear success metrics.
- Design solution architectures that integrate LLMs with enterprise systems, data sources, and tool/function calling while meeting latency and reliability expectations.
- Develop prototypes rapidly and validate them through evaluation, red-teaming, and user feedback; document tradeoffs and recommendations.
Production Engineering & Enterprise Readiness
- Build production-grade services and full-stack experiences (APIs, UIs, workflows) with secure authentication/authorization, audit logging, and scalable deployment patterns.
- Implement safety, privacy, and compliance controls (e.g., PHI/PII protection, prompt injection defenses, data residency constraints, and policy-based filtering).
- Instrument solutions end-to-end with metrics, traces, logs, and model/app observability; contribute to SLOs, error budgets, and operational runbooks.
Model Enablement & Evaluation
- Build and maintain evaluation harnesses for LLM quality, safety, and business outcomes (offline tests, golden sets, regression suites, and online experiments).
- Implement RAG pipelines (chunking, embedding, vector search, reranking) and optimize for accuracy, cost, and latency.
- Collaborate with platform teams on deployment, monitoring, drift/quality detection, and incident response for model-backed services.
Reusable Components & Engineering Excellence
- Contribute reusable libraries and patterns for prompt management, retrieval, tool calling, and policy enforcement.
- Participate in design reviews and code reviews; mentor senior and mid-level engineers on GenAI engineering practices.
- Continuously improve developer experience through templates, CI/CD automation, and documentation that accelerates safe adoption.
BASIC QUALIFICATIONS
- 7+ years of software engineering supporting Data or AI/ML initiatives, including building and operating production services.
- 3+ years applying ML/AI in production; demonstrated hands-on GenAI delivery (LLMs, RAG, evaluation, and safety controls).
- 3+ years of experience delivering solutions in high-scale, high-availability environments with strong security and compliance requirements.
PREFERRED QUALIFICATIONS
- Strong full-stack engineering skills (backend services, APIs, and modern web application development) with a focus on reliability and security.
- Hands-on expertise with LLM application patterns: RAG, tool/function calling, prompt management, evaluation, and guardrails.
- Experience with Python and at least one additional backend language; familiarity with common ML libraries and serving frameworks.
- Working knowledge of containerization and Kubernetes, CI/CD, infrastructure-as-code concepts, and production observability.
- Ability to communicate clearly, influence across teams, and translate business needs into implementable technical plans.
Education
- Bachelor’s degree or equivalent experience (High School Diploma and 4 years relevant experience).
PAY RANGE
The typical pay range for this role is:
$106,605.00 - $284,280.00
This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, geography and other relevant factors. This position is eligible for a CVS Health bonus, commission or short-term incentive program in addition to the base pay range listed above. This position also includes an award target in the company’s equity award program.
Our people fuel our future. Our teams reflect the customers, patients, members and communities we serve and we are committed to fostering a workplace where every colleague feels valued and that they belong.
GREAT BENEFITS FOR GREAT PEOPLE
We take pride in offering a comprehensive and competitive mix of pay and benefits that reflects our commitment to our colleagues and their families.
This full-time position is eligible for a comprehensive benefits package designed to support the physical, emotional, and financial well-being of colleagues and their families. The benefits for this position include medical, dental, and vision coverage, paid time off, retirement savings options, wellness programs, and other resources, based on eligibility.
Additional details about available benefits are provided during the application process and on Benefits Moments.
We anticipate the application window for this opening will close on: 04/21/2026
Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state and local laws.

INTRODUCTION
We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time.
At CVS Health, our purpose is to deliver better health outcomes by meeting consumers where they are—through local care, digital experiences, and a nationwide team committed to quality, safety, and affordability.
Our Solutions Engineering and Infrastructure organization is building an enterprise AI/ML capability that delivers reliable, responsible, and secure AI-powered platforms and solutions at Fortune 5 scale, and this role is foundational to help us develop that capability.
This is a senior individual-contributor role, focused on identifying evaluating and documenting high-value use cases, designing and prototyping AI-powered solutions, and evolving them into secure, resilient, enterprise-ready products and platform components.
ROLE AND RESPONSIBILITIES
Key Responsibilities:
AI Solution Design & Prototyping
- Partner with stakeholders to identify, evaluate, document, and shape GenAI use cases (copilots, automation, decision support, and insight generation) with clear success metrics.
- Design solution architectures that integrate LLMs with enterprise systems, data sources, and tool/function calling while meeting latency and reliability expectations.
- Develop prototypes rapidly and validate them through evaluation, red-teaming, and user feedback; document tradeoffs and recommendations.
Production Engineering & Enterprise Readiness
- Build production-grade services and full-stack experiences (APIs, UIs, workflows) with secure authentication/authorization, audit logging, and scalable deployment patterns.
- Implement safety, privacy, and compliance controls (e.g., PHI/PII protection, prompt injection defenses, data residency constraints, and policy-based filtering).
- Instrument solutions end-to-end with metrics, traces, logs, and model/app observability; contribute to SLOs, error budgets, and operational runbooks.
Model Enablement & Evaluation
- Build and maintain evaluation harnesses for LLM quality, safety, and business outcomes (offline tests, golden sets, regression suites, and online experiments).
- Implement RAG pipelines (chunking, embedding, vector search, reranking) and optimize for accuracy, cost, and latency.
- Collaborate with platform teams on deployment, monitoring, drift/quality detection, and incident response for model-backed services.
Reusable Components & Engineering Excellence
- Contribute reusable libraries and patterns for prompt management, retrieval, tool calling, and policy enforcement.
- Participate in design reviews and code reviews; mentor senior and mid-level engineers on GenAI engineering practices.
- Continuously improve developer experience through templates, CI/CD automation, and documentation that accelerates safe adoption.
BASIC QUALIFICATIONS
- 7+ years of software engineering supporting Data or AI/ML initiatives, including building and operating production services.
- 3+ years applying ML/AI in production; demonstrated hands-on GenAI delivery (LLMs, RAG, evaluation, and safety controls).
- 3+ years of experience delivering solutions in high-scale, high-availability environments with strong security and compliance requirements.
PREFERRED QUALIFICATIONS
- Strong full-stack engineering skills (backend services, APIs, and modern web application development) with a focus on reliability and security.
- Hands-on expertise with LLM application patterns: RAG, tool/function calling, prompt management, evaluation, and guardrails.
- Experience with Python and at least one additional backend language; familiarity with common ML libraries and serving frameworks.
- Working knowledge of containerization and Kubernetes, CI/CD, infrastructure-as-code concepts, and production observability.
- Ability to communicate clearly, influence across teams, and translate business needs into implementable technical plans.
Education
- Bachelor’s degree or equivalent experience (High School Diploma and 4 years relevant experience).
PAY RANGE
The typical pay range for this role is:
$106,605.00 - $284,280.00
This pay range represents the base hourly rate or base annual full-time salary for all positions in the job grade within which this position falls. The actual base salary offer will depend on a variety of factors including experience, education, geography and other relevant factors. This position is eligible for a CVS Health bonus, commission or short-term incentive program in addition to the base pay range listed above. This position also includes an award target in the company’s equity award program.
Our people fuel our future. Our teams reflect the customers, patients, members and communities we serve and we are committed to fostering a workplace where every colleague feels valued and that they belong.
GREAT BENEFITS FOR GREAT PEOPLE
We take pride in offering a comprehensive and competitive mix of pay and benefits that reflects our commitment to our colleagues and their families.
This full-time position is eligible for a comprehensive benefits package designed to support the physical, emotional, and financial well-being of colleagues and their families. The benefits for this position include medical, dental, and vision coverage, paid time off, retirement savings options, wellness programs, and other resources, based on eligibility.
Additional details about available benefits are provided during the application process and on Benefits Moments.
We anticipate the application window for this opening will close on: 04/21/2026
Qualified applicants with arrest or conviction records will be considered for employment in accordance with all federal, state and local laws.
Machine Learning Engineer Job Roles in Missouri
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Search Machine Learning Engineer Jobs in MissouriMachine Learning Engineer Jobs in Missouri: Frequently Asked Questions
Which companies sponsor visas for machine learning engineers in Missouri?
St. Louis and Kansas City host the state's most active sponsors for machine learning engineers. Companies like Cerner (now part of Oracle Health), Boeing, Express Scripts, and Mastercard's Kansas City operations have filed H-1B petitions for ML and data science roles. Larger employers with dedicated technology divisions are generally more experienced with visa sponsorship than smaller startups in the state.
Which visa types are most common for machine learning engineer roles in Missouri?
The H-1B is the most common visa for machine learning engineers in Missouri, as the role typically qualifies as a specialty occupation requiring a bachelor's degree or higher in computer science, statistics, or a related field. Candidates already holding OPT or STEM OPT through Missouri universities like Washington University in St. Louis or Missouri University of Science and Technology may transition to H-1B sponsorship through an employer petition.
Which cities in Missouri have the most machine learning engineer sponsorship jobs?
St. Louis accounts for the largest concentration of machine learning engineer roles with visa sponsorship in Missouri, driven by its healthcare IT, financial services, and aerospace sectors. Kansas City is a secondary hub with growing activity in fintech and enterprise software. Columbia has a smaller but emerging presence connected to the University of Missouri's research and technology ecosystem.
How to find machine learning engineer visa sponsorship jobs in Missouri?
Migrate Mate filters job listings specifically by visa sponsorship availability, making it straightforward to identify Missouri employers actively seeking machine learning engineers and willing to sponsor. Rather than sorting through general job boards, you can search directly for ML engineer roles in Missouri on Migrate Mate and see which companies have a documented history of sponsoring international candidates in technical roles.
Are there any state-specific considerations for machine learning engineers seeking sponsorship in Missouri?
Missouri does not impose state-level restrictions on work visa sponsorship, so federal H-1B rules govern the process. One practical factor is the university pipeline: institutions like Washington University in St. Louis and Missouri S&T produce ML talent and maintain industry partnerships, which can influence which local employers are accustomed to hiring and sponsoring international graduates. Employers sponsoring H-1B workers must meet Department of Labor prevailing wage requirements for the St. Louis or Kansas City metropolitan areas, depending on job location.
What is the prevailing wage for sponsored machine learning engineer jobs in Missouri?
U.S. employers sponsoring a visa must pay at least the prevailing wage, which is what workers in the same role, area, and experience level typically earn. The Department of Labor sets this rate to make sure companies aren't hiring foreign workers simply because they'd accept lower pay than a U.S. worker. It varies by job title, location, and experience. You can look up current prevailing wage rates for any occupation and location using the OFLC Wage Search page.
See which machine learning engineer employers are hiring and sponsoring visas in Missouri right now.
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