Acute Care Nurse Practitioner Jobs in Missouri
Acute Care Nurse Practitioner jobs in Missouri are open across Springfield, Albany, and Florissant and other Missouri metros, with employers like CoxHealth, Fresenius Medical Care, and Lester E. Cox Medical Centers hiring at every experience level. Find a role that fits below and apply directly.
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PURPOSE AND SCOPE:
The professional registered nurse Inpatient Services RN CAP 1 is an entry level designation into the Clinical Advancement Program (CAP). This position is accountable and responsible for the provision and coordination of clinically competent care including assessment, planning, intervention and evaluation for an assigned group of patients. This may include delegation of appropriate tasks to direct patient care staff including but not limited to RNs, LVN/LPNs and Patient Care Technicians. As a member of the kidney disease health care team, this position participates in decision-making, teaching, leadership functions, and quality improvement activities that enhance patient care outcomes and program operations.
PRINCIPAL DUTIES AND RESPONSIBILITIES:
All duties and responsibilities are expected to be performed in accordance with Fresenius Kidney Care, policy, procedures, standards of nursing practice, applicable contractual service agreements, state and federal regulations.
- Performs all essential functions under the direction of the Supervisor and with guidance from the Educator, Preceptor or in collaboration with another Registered Nurse.
- Performs ongoing, systematic collection and analysis of patient data pre – during – post treatment for assigned patients and documents in the patient medical record, makes adjustments and modifications to treatment plan as indicated and notifies Supervisor, Physician, patient’s primary nurse and others as may be indicated.
- Assesses, collaborates and documents patient/family’s basic learning needs to provide initial and ongoing education to patients and family.
- Recognizes aspects and implications of patient status that vary from normal and reports to or collaborates with appropriate health team members for input including but not limited to Supervisor, appropriate physician, and the contracted facility primary Nurse.
- Directs and provides safe effective patient care for assigned patients as prescribed for all modality specific treatment procedures.
- Assesses daily assigned patient care needs and collaborates with direct and ancillary patient care staff as needed.
- Initiates and coordinates communication with FKC and Non-FKC dialysis providers and appropriate contracted facility personnel as needed to provide continuity of patient care.
- Performs the implementation, administration, monitoring, and documentation of patient's response to prescribed intradialytic transfusions, including appropriate notification of adverse reactions to physician and appropriate blood supplier.
- Administers medications as prescribed and documents appropriate medical justification and effectiveness.
- Initiates and assists with emergency response measures.
- Serves as a resource for health care team, participates in staff training and orientation of new staff as assigned.
- May be asked to provide specialized nursing care instruction to hospital/facility staff as stipulated contractually.
- May be assigned to assist in an Outpatient facility on an as needed basis.
- Required to complete CAP requirements to advance.
- Performs all other duties as assigned by Supervisor.
PHYSICAL DEMANDS AND WORKING CONDITIONS:
The physical demands and work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
- The position provides direct patient care that regularly involves heavy lifting, moving of patients and assisting with ambulation. Equipment aids and/or coworkers may provide assistance.
- This position requires frequent, prolonged periods of standing and the employee must be able to bend over.
- The employee may occasionally be required to move, with assistance, machines and equipment of up to 200 lbs., and may lift chemical and water solutions of up to 30 lbs. as high as 5 feet.
- The work environment is characteristic of a health care facility with air temperature control and moderate noise levels.
- May be exposed to infectious and contagious diseases/materials.
- May be asked to provide essential functions of this position in other locations with the same physical demands and working conditions as described above.
- Day to day work includes, desk work, computer work, interaction with patients, facility/hospital staff and physicians.
- The position requires travel to training/meeting sites and between assigned facilities.
- Position requires participation in on-call rotation, night, weekend, holiday or as defined by individual program needs.
SUPERVISION:
Assigned oversight of Patient Care Technicians/LVN/LPNs/RNs as a designated Nurse in Charge, after meeting all the following:
- Successful completion of all FKC education and modality specific training requirements for new employees.
- Must have a minimum of 9 months experience as a RN.
- 6 months experience in acute dialysis as a RN.
EDUCATION and LICENSURE:
- Graduate of an accredited School of Nursing.
- Current appropriate state licensure.
- Current or successful completion of CPR BLS Certification.
- Must meet the practice requirements in all states in which he or she is employed.
EXPERIENCE AND REQUIRED SKILLS:
- Entry level for RNs with less than 2 years of Nephrology Nursing experience as an RN.
- Minimum 9 months experience as a Registered Nurse, 12 months (preferred).
- 6 months acute dialysis experience (preferred).
- Hemodialysis and/or ICU experience (preferred).
ACKNOWLEDGEMENT:
I acknowledge that I have read and accepted this job description. I understand what is expected of me in this position, and I am able to perform the essential functions as outlined with or without reasonable accommodation. Furthermore, I understand that the duties and responsibilities listed in this job description are intended only as illustrations of the various types of work that may be performed. The omission of specific statements of duties does not exclude them from the position if the work is similar, related, or a logical assignment to the position. If I have any questions about duties and responsibilities not specified in this job description that I am asked to perform, I should discuss them with my immediate Supervisor or my Human Resources representative.
Fresenius Medical Care maintains a drug-free workplace in accordance with applicable federal and state laws.
EOE, disability/veterans
See All 8 Acute Care Nurse Practitioner Jobs in Missouri
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Find JobsAcute Care Nurse Practitioner Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Acute Care Nurse Practitioner Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring
- CoxHealth3

- Fresenius Medical Care2

- Lester E. Cox Medical Centers2

- Mosaic Life Care1

Top Industries Hiring
- Healthcare & Medical Services7
What Missouri Employers Look For
The qualifications that appear most often in acute care nurse practitioner jobs across Missouri.
- Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
- ACNPC-AG or AGACNP certification from ANCC or AACN
- Active unrestricted RN and APRN licensure in the state of employment
- Minimum one to two years of acute or critical care clinical experience as an RN or NP
- Current BLS, ACLS, and often PALS certification
- Proficiency with electronic health record systems such as Epic or Cerner
Acute Care Nurse Practitioner Jobs in Missouri: Frequently Asked Questions
How many acute care nurse practitioner jobs are there in Missouri?
There are 8+ acute care nurse practitioner openings in Missouri on Migrate Mate as of June 2026, with the most roles in Springfield, Albany, and Florissant. New positions post regularly as employers across Missouri hire.
How much do acute care nurse practitioners make in Missouri?
Acute care nurse practitioners in Missouri earn a median of about $129,930 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $100,650 for the lowest 10% to over $162,060 for the top 10%. Pay rises with experience, specialty, and employer.
Which Missouri cities have the most acute care nurse practitioner jobs?
Springfield, Albany, and Florissant have the most acute care nurse practitioner openings in Missouri right now, with additional roles spread across smaller metros statewide.
Which companies hire acute care nurse practitioners in Missouri?
Employers hiring acute care nurse practitioners in Missouri include CoxHealth, Fresenius Medical Care, and Lester E. Cox Medical Centers, based on current listings on Migrate Mate as of June 2026.
Are there remote acute care nurse practitioner jobs in Missouri?
Yes. About 13% of acute care nurse practitioner openings tied to Missouri are remote or hybrid as of June 2026. The rest are on-site roles based in Missouri metros.
How do I apply for acute care nurse practitioner jobs in Missouri?
You can apply to acute care nurse practitioner jobs in Missouri directly on Migrate Mate. Search the listings above, find roles that match your experience and preferred Missouri location, then apply to each one that fits.
See All 8 Acute Care Nurse Practitioner Jobs in Missouri
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