Acute Care Nurse Practitioner Jobs in Arizona
Acute Care Nurse Practitioner jobs in Arizona are in strong and consistent demand, concentrated in hospital-based acute and critical care, emergency medicine, and specialty inpatient units at every level from new graduate ACNP through senior and lead practitioner roles. Phoenix, Tucson, and the East Valley are the primary hiring centers, where large systems including Banner Health, Dignity Health, and HonorHealth maintain deep and ongoing ACNP pipelines. The most active subspecialty areas are cardiology, pulmonology, and post-surgical care. Find a role that fits below and apply directly.
Find JobsOverview
Showing 5 of 8+ Acute Care Nurse Practitioner jobs











City:Phoenix
State:AZ
Remote:No
Department:Hematology
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans – to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
- Medical: Multiple plan options.
- Dental: Delta Dental or reimbursement account for flexible coverage.
- Vision: Affordable plan with national network.
- Pre-Tax Savings: HSA and FSAs for eligible expenses.
- Retirement: Competitive retirement package to secure your future.
Responsibilities
Mayo Clinic Arizona is seeking dedicated individuals to join our dynamic Blood & Marrow Transplant (BMT) team. This is an exciting opportunity to make a meaningful impact in the lives of patients undergoing hematology, transplant, and cellular therapy treatments. We’re looking for team players who are driven by excellence and a deep sense of empathy for patients and their families.
Position Highlights:
- Integral role in both the Cellular Therapy Clinic and inpatient BMT unit
- 12 hour daytime shifts
- Rotational schedule including holidays and weekends
- Potential future rotation to outpatient clinic or night coverage (not currently required)
- Supportive team environment with strong collaboration and camaraderie
During the selection process you may participate in an OnDemand (pre-recorded) interview that you can complete at your convenience. During the OnDemand interview, a question will appear on your screen, and you will have time to consider each question before responding. You will have the opportunity to re-record your answer to each question – Mayo Clinic will only see the final recording. The complete interview will be reviewed by a Mayo Clinic staff member and you will be notified of next steps.
Qualifications
Acute Care Nurse Practitioner: Masters-prepared graduate of an accredited school of nursing and Nurse Practitioner program. Current AZ RN and APRN license and certification as an ACNP.
Physician Assistant: Graduate of accredited Physician Assistant program with current PA certification by NCCPA and registration as a PA by the AZ State Board of Medical Practice.
Additional Qualifications:
- Preferred Hematology APP experience and/or fellowship, new grads with RN or clinical Hematology exp can be considered.
- Active BLS and ACLS certification from American Heart Association or American Red Cross at start date and DEA registration required.
Exemption Status
Exempt
Compensation Detail
Education, experience and tenure may be considered along with internal equity when job offers are extended.
Benefits Eligible
Yes
Schedule
Full Time
Hours/Pay Period
80
Schedule Details
12 hour day shifts with rotating holidays and weekends. Possibility of night coverage in the future.
Weekend Schedule
Rotating weekends
International Assignment
No
Site Description
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law". Mayo Clinic participates in E-Verify and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter
LaTasha Perkins
See All 8 Acute Care Nurse Practitioner Jobs in Arizona
Find roles in Arizona that match your experience and apply in just a few clicks.
Find JobsAcute Care Nurse Practitioner Jobs by City in Arizona
Where Arizona roles are concentrated, by current openings.
Acute Care Nurse Practitioner Job Market in Arizona
A snapshot from current Arizona openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Education
- Healthcare & Medical Services
What Arizona Employers Look For
The qualifications that appear most often in acute care nurse practitioner jobs across Arizona.
- Active Arizona Nurse Practitioner license and ACNP-BC or AGACNP-BC national certification required
- Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
- Arizona Prescriptive Authority approval and current DEA registration for controlled substances
- Minimum one to two years of acute care or critical care clinical experience preferred
- Current BLS, ACLS, and PALS certifications from the American Heart Association
- Ability to independently manage complex inpatient caseloads with minimal physician oversight
Acute Care Nurse Practitioner Jobs in Arizona: Frequently Asked Questions
How do you become a acute care nurse practitioner in Arizona?
Becoming an acute care nurse practitioner in Arizona requires completing an accredited MSN or DNP program with an acute care NP concentration, then passing either the ACNP-BC or AGACNP-BC national certification exam. You then apply for NP licensure and Prescriptive Authority through the Arizona State Board of Nursing. Arizona uses a reduced-supervision practice model, so new ACNPs work under a written collaborative agreement with a physician during an initial practice period before transitioning to independent practice.
How much do acute care nurse practitioners make in Arizona?
Acute care nurse practitioners in Arizona earn a median of about $134,420 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $104,400 for the lowest 10% to over $173,270 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire acute care nurse practitioners in Arizona?
Employers hiring acute care nurse practitioners in Arizona right now include Mayo Clinic, Tucson Medical Center, and City of Hope, based on current listings on Migrate Mate as of August 2026. Arizona's large integrated health systems maintain consistent ACNP hiring across their inpatient, hospitalist, and specialty units throughout the Phoenix and Tucson metro areas.
Which Arizona cities have the most acute care nurse practitioner jobs?
The cities with the most acute care nurse practitioner openings in Arizona are Phoenix, Tucson, and Goodyear. Phoenix dominates the distribution as the state's largest metro, anchored by Banner Health's flagship hospitals and Dignity Health's regional network, while Tucson draws strong ACNP hiring through Banner University Medical Center and the University of Arizona Health Network, and suburban East Valley cities like Mesa and Chandler support additional volume through HonorHealth and regional specialty centers.
Are there remote acute care nurse practitioner jobs in Arizona?
Yes, but they're rare. Acute care nurse practitioners work hands-on with inpatient and acutely ill patients, which makes full remote work uncommon by the nature of the role. About 0% of acute care nurse practitioner openings tied to Arizona are remote or hybrid as of August 2026, and those positions are almost exclusively in telehealth triage, utilization review, or post-discharge care management rather than direct bedside practice.
How can I get hired as a acute care nurse practitioner in Arizona with little or no experience?
The most realistic entry path is applying to new-graduate ACNP residency or fellowship programs run by Banner Health and Dignity Health in the Phoenix area, which are specifically designed for candidates coming straight out of their NP program. Lateral moves from experienced RN roles in ICU, step-down, or emergency departments are viewed favorably because bedside critical care experience translates directly. Holding an active Arizona NP license, completing your collaborative agreement paperwork in advance, and obtaining ACLS and PALS certifications before applying will strengthen any application significantly.
Where can I find and apply to acute care nurse practitioner jobs in Arizona?
You can find and apply to acute care nurse practitioner jobs in Arizona on Migrate Mate, which lists current Arizona openings across hospital systems, specialty practices, and inpatient settings. Find the roles that fit your credentials and experience and apply directly.
See All 8 Acute Care Nurse Practitioner Jobs in Arizona
Find roles in Arizona that match your experience and apply in just a few clicks.
Find Jobs