Acute Care Nurse Practitioner Jobs

Acute Care Nurse Practitioner jobs are open across hospital systems, academic medical centers, and specialty practices, from new-grad to experienced clinician, with concentrations in critical care, cardiology, and pulmonology. Find a role that fits from the openings below and apply directly.

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Overview

Open roles282+
Top stateTexas
Top employerNorthwestern Medicine
Top cityHouston, TX
Work type97% On-site
Top industryHealthcare

Showing 5 of 282+ Acute Care Nurse Practitioner jobs

Nurse Practitioner Hub
Acute Care in the Home NP / PA (Mobile Role) | 3 Days Week | $196K | Full Benefits
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Nurse Practitioner Hub
Added 1d ago
Acute Care in the Home NP / PA (Mobile Role) | 3 Days Week | $196K | Full Benefits
Nurse Practitioner Hub
New York, New York
Healthcare Administration
Nursing
Patient Services & Wellbeing
$177k - $198k/yr
BLS Certification
11-50

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Ochsner Health
Acute Care Nurse Practitioner - Physician Assistant - Thoracic Cardio Vascular Surgical ICU - FT
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Ochsner Health
Added 1d ago
Acute Care Nurse Practitioner - Physician Assistant - Thoracic Cardio Vascular Surgical ICU - FT
Ochsner Health
New Orleans, Louisiana
Healthcare Administration
Patient Services & Wellbeing
Physicians
On-Site
BLS Certification
10,000+

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INTEGRIS Health
Acute Care Nurse Practitioner - 7on/7off Nights - Hospitalists
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INTEGRIS Health
Added 2d ago
Acute Care Nurse Practitioner - 7on/7off Nights - Hospitalists
INTEGRIS Health
Oklahoma City, Oklahoma
Healthcare Administration
Patient Services & Wellbeing
Social Work & Counseling
BLS Certification
10,000+

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Houston Methodist
Nurse Practitioner Acute Care
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Houston Methodist
Added 2d ago
Nurse Practitioner Acute Care
Houston Methodist
Houston, Texas
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
Master's
10,000+

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Houston Methodist
Nurse Practitioner Acute Care
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Houston Methodist
Added 2d ago
Nurse Practitioner Acute Care
Houston Methodist
Sugar Land, Texas
Nursing
Healthcare Administration
Patient Services & Wellbeing
On-Site
Master's
10,000+

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Top Cities Hiring Acute Care Nurse Practitioners

Explore acute care nurse practitioner openings in the cities hiring most right now.

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Acute Care Nurse Practitioner Job Market

Who's Hiring

  • Northwestern Medicine
    Northwestern Medicine20
  • Baylor Scott & White Health
    Baylor Scott & White Health20
  • Houston Methodist
    Houston Methodist14
  • NYU Langone Health
    NYU Langone Health12
  • Penn Medicine
    Penn Medicine9

Top Industries Hiring

  • Healthcare & Medical Services96
  • Education22
  • Agriculture & Farming4
  • Insurance3
  • Consulting & Professional Services3

What Employers Look For

The qualifications that appear most often in acute care nurse practitioner jobs.

  • Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
  • ACNPC-AG or AGACNP certification from ANCC or AACN
  • Active unrestricted RN and APRN licensure in the state of employment
  • Minimum one to two years of acute or critical care clinical experience as an RN or NP
  • Current BLS, ACLS, and often PALS certification
  • Proficiency with electronic health record systems such as Epic or Cerner

Tips for Your Acute Care Nurse Practitioner Job Search

Tailor your resume to patient acuity

Hiring managers for acute care roles scan for evidence of managing high-acuity patients independently. Quantify your case complexity, ventilator management experience, or procedural skills like central line placement rather than listing general NP duties.

Highlight your ACNPC-AG or AGACNP credential prominently

Many acute care postings screen out candidates who bury their certification. Place your adult-gerontology acute care NP credential directly after your name on your resume so recruiters and ATS filters catch it in the first pass.

Filter openings by inpatient versus outpatient scope

Acute care NP postings vary widely in actual setting. Read the job description for phrases like rapid response team, ICU rounding, or hospitalist model to confirm the role matches your clinical background before you apply.

Apply early to roles that fit

Migrate Mate lists acute care nurse practitioner openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Prepare for a clinical scenario interview

Acute care NP interviews often include a rapid-assessment scenario, such as a deteriorating sepsis patient or acute respiratory failure. Practice walking through your clinical reasoning aloud, including your differential, orders, and escalation decision, so your thought process is clear under pressure.

Negotiate scope of practice before accepting

Before signing an offer, ask specifically which procedures you will perform independently, how physician collaboration is structured, and whether the role includes on-call obligations. These details directly affect workload and professional satisfaction and are often negotiable at the offer stage.

Acute Care Nurse Practitioner Jobs: Frequently Asked Questions

Which companies are hiring the most acute care nurse practitioners?

The companies hiring the most acute care nurse practitioners right now include Northwestern Medicine, Baylor Scott & White Health, and Houston Methodist, with the largest share of openings in Texas, Illinois, and New York, based on current listings on Migrate Mate as of August 2026. Large health systems and academic medical centers consistently post the highest volume of acute care NP roles.

How many acute care nurse practitioner jobs are remote?

About 3% of acute care nurse practitioner openings are fully remote or hybrid as of August 2026, reflecting the hands-on nature of most acute care settings. The sub-areas most likely to offer remote or telehealth components include post-discharge follow-up, tele-ICU consultation, and chronic disease management programs attached to acute care systems.

How do you become an acute care nurse practitioner?

You become an acute care nurse practitioner by earning a Bachelor of Science in Nursing, passing the NCLEX-RN, and gaining clinical experience as a registered nurse, ideally in an ICU, ED, or step-down unit. You then complete a graduate-level acute care NP program and pass the ACNPC-AG or AGACNP board exam before applying for APRN licensure in your state.

Can you get hired as an acute care nurse practitioner with little experience?

Yes, some health systems hire new-graduate acute care NPs, particularly those with strong RN backgrounds in critical care or emergency settings. New-grad acute care NP fellowships and residency programs at larger academic hospitals offer structured onboarding and are a practical entry point. Prioritizing postings that explicitly list new graduates as eligible will narrow your search to realistic targets.

What does the acute care nurse practitioner interview process look like?

The acute care NP interview typically begins with a phone or video screen with a recruiter or nurse manager, followed by an in-person panel that includes physicians, fellow NPs, and sometimes nursing leadership. Most hospitals include a clinical scenario or case presentation to assess your diagnostic reasoning. A credentialing review and reference check follow before an offer is extended.

Where can I find and apply to acute care nurse practitioner jobs?

You can find and apply to acute care nurse practitioner jobs on Migrate Mate, which lists current openings from across the United States. Find roles that match your specialty, setting, and location, then apply directly to each listing from the same place.

See All 282+ Acute Care Nurse Practitioner Jobs

Find roles that match your experience and apply in just a few clicks.

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