Acute Care Nurse Practitioner Jobs

Acute Care Nurse Practitioner jobs are open across hospital systems, academic medical centers, and specialty practices, from new-grad to experienced clinician, with concentrations in critical care, cardiology, and pulmonology. Find a role that fits from the openings below and apply directly.

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Overview

Open roles283+
Top stateTexas
Top employerHouston Methodist
Top cityHouston, TX
Work type95% On-site
Top industryHealthcare

Showing 5 of 283+ Acute Care Nurse Practitioner jobs

MD Anderson Cancer Center
Nocturnal Advanced Practice Provider - Acute Care Services
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MD Anderson Cancer Center
New 18h ago
Nocturnal Advanced Practice Provider - Acute Care Services
MD Anderson Cancer Center
Houston, Texas
Healthcare Administration
Nursing
Patient Services & Wellbeing
$118k - $177k/yr
On-Site
CPR Certification
10,000+

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Capital Health
Acute Neurology Nurse Practitioner / Physician Assistant
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Capital Health
New 23h ago
Acute Neurology Nurse Practitioner / Physician Assistant
Capital Health
Trenton, New Jersey
Administrative & Office Support
Executive Assistant & Personal Assistant
Human Resources (HR) — Generalist
$120k.6 - $171k/yr
Post-Master's Certificate (Nursing)
1,001-5,000

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Northwestern Medicine
Acute Care Nurse Practitioner or Physician Assistant - Neurology, Full-time, Days
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Northwestern Medicine
Added 1d ago
Acute Care Nurse Practitioner or Physician Assistant - Neurology, Full-time, Days
Northwestern Medicine
Lake Forest, Illinois
Clinical Trials
Healthcare Administration
Nursing
Patient Services & Wellbeing
$61 - $79.67/hr
BLS Certification
10,000+

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TeamHealth
Part-Time Post-Acute Care Nurse Practitioner In Seattle, WA
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TeamHealth
Added 1d ago
Part-Time Post-Acute Care Nurse Practitioner In Seattle, WA
TeamHealth
Seattle, Washington
Healthcare Administration
Medical Assistant
Patient Services & Wellbeing
$60k - $72k/yr
10,000+

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Houston Methodist
Nurse Practitioner Acute Care, PRN - ICU/Cert Days/Nights (Sugarland)
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Houston Methodist
Added 1d ago
Nurse Practitioner Acute Care, PRN - ICU/Cert Days/Nights (Sugarland)
Houston Methodist
Sugar Land, Texas
Executive Leadership & C-Suite
Program Management
Project Management
BLS Certification
10,000+

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Top Cities Hiring Acute Care Nurse Practitioners

Explore acute care nurse practitioner openings in the cities hiring most right now.

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Acute Care Nurse Practitioner Job Market

Who's Hiring

  • Houston Methodist
    Houston Methodist27
  • Baylor Scott & White Health
    Baylor Scott & White Health24
  • Cleveland Clinic
    Cleveland Clinic14
  • TeamHealth
    TeamHealth11
  • Penn Medicine
    Penn Medicine9

Top Industries Hiring

  • Healthcare & Medical Services73
  • Education15
  • Consulting & Professional Services2
  • Insurance1
  • Science & Research1

What Employers Look For

The qualifications that appear most often in acute care nurse practitioner jobs.

  • Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
  • ACNPC-AG or AGACNP certification from ANCC or AACN
  • Active unrestricted RN and APRN licensure in the state of employment
  • Minimum one to two years of acute or critical care clinical experience as an RN or NP
  • Current BLS, ACLS, and often PALS certification
  • Proficiency with electronic health record systems such as Epic or Cerner

Tips for Your Acute Care Nurse Practitioner Job Search

Tailor your resume to patient acuity

Hiring managers for acute care roles scan for evidence of managing high-acuity patients independently. Quantify your case complexity, ventilator management experience, or procedural skills like central line placement rather than listing general NP duties.

Highlight your ACNPC-AG or AGACNP credential prominently

Many acute care postings screen out candidates who bury their certification. Place your adult-gerontology acute care NP credential directly after your name on your resume so recruiters and ATS filters catch it in the first pass.

Filter openings by inpatient versus outpatient scope

Acute care NP postings vary widely in actual setting. Read the job description for phrases like rapid response team, ICU rounding, or hospitalist model to confirm the role matches your clinical background before you apply.

Apply early to roles that fit

Migrate Mate lists acute care nurse practitioner openings from across the United States in one place, so you can find roles that match and apply directly to each listing.

Prepare for a clinical scenario interview

Acute care NP interviews often include a rapid-assessment scenario, such as a deteriorating sepsis patient or acute respiratory failure. Practice walking through your clinical reasoning aloud, including your differential, orders, and escalation decision, so your thought process is clear under pressure.

Negotiate scope of practice before accepting

Before signing an offer, ask specifically which procedures you will perform independently, how physician collaboration is structured, and whether the role includes on-call obligations. These details directly affect workload and professional satisfaction and are often negotiable at the offer stage.

Acute Care Nurse Practitioner Jobs: Frequently Asked Questions

Which companies are hiring the most acute care nurse practitioners?

The companies hiring the most acute care nurse practitioners right now include Houston Methodist, Baylor Scott & White Health, and Cleveland Clinic, with the largest share of openings in Texas, Ohio, and New York, based on current listings on Migrate Mate as of September 2026. Large health systems and academic medical centers consistently post the highest volume of acute care NP roles.

How many acute care nurse practitioner jobs are remote?

About 5% of acute care nurse practitioner openings are fully remote or hybrid as of September 2026, reflecting the hands-on nature of most acute care settings. The sub-areas most likely to offer remote or telehealth components include post-discharge follow-up, tele-ICU consultation, and chronic disease management programs attached to acute care systems.

How do you become an acute care nurse practitioner?

You become an acute care nurse practitioner by earning a Bachelor of Science in Nursing, passing the NCLEX-RN, and gaining clinical experience as a registered nurse, ideally in an ICU, ED, or step-down unit. You then complete a graduate-level acute care NP program and pass the ACNPC-AG or AGACNP board exam before applying for APRN licensure in your state.

Can you get hired as an acute care nurse practitioner with little experience?

Yes, some health systems hire new-graduate acute care NPs, particularly those with strong RN backgrounds in critical care or emergency settings. New-grad acute care NP fellowships and residency programs at larger academic hospitals offer structured onboarding and are a practical entry point. Prioritizing postings that explicitly list new graduates as eligible will narrow your search to realistic targets.

What does the acute care nurse practitioner interview process look like?

The acute care NP interview typically begins with a phone or video screen with a recruiter or nurse manager, followed by an in-person panel that includes physicians, fellow NPs, and sometimes nursing leadership. Most hospitals include a clinical scenario or case presentation to assess your diagnostic reasoning. A credentialing review and reference check follow before an offer is extended.

Where can I find and apply to acute care nurse practitioner jobs?

You can find and apply to acute care nurse practitioner jobs on Migrate Mate, which lists current openings from across the United States. Find roles that match your specialty, setting, and location, then apply directly to each listing from the same place.

See All 283+ Acute Care Nurse Practitioner Jobs

Find roles that match your experience and apply in just a few clicks.

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