Application Engineer Jobs in Boston, MA

Application Engineer jobs in Boston are in strong demand, concentrated in the Seaport District, Kendall Square, and Back Bay across life sciences, defense technology, and enterprise software. Employers hiring right now include CVS Health, Ryder System, and Datadog. See the openings below and apply to the ones that match your experience.

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Overview

Open roles42
Top employerCVS Health
Work type45% Remote
Top credentialBachelor's
Companies hiring17

Showing 5 of 42+ Application Engineer jobs

CVS Health
Staff Application Security Engineer – Threat Research
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CVS Health
Added 1d ago
Staff Application Security Engineer – Threat Research
CVS Health
Boston, Massachusetts
Compliance & Risk
Cybersecurity
Security Engineering
$107k - $284k/yr
High school diploma or GED
10,000+

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CVS Health
Staff Application Security Engineer – AI & Agentic Systems
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CVS Health
Added 1d ago
Staff Application Security Engineer – AI & Agentic Systems
CVS Health
Boston, Massachusetts
Engineering (Non-Software)
Systems Administration
Technical Program Management
$107k - $284k/yr
High school diploma or GED
10,000+

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Ryder System
Saleforce Application Development and Support Engineer II
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Ryder System
Added 2d ago
Saleforce Application Development and Support Engineer II
Ryder System
Boston, Massachusetts
Automation QA
Cloud & DevOps
DevOps
$60k - $80k/yr
Bachelor's degree in management information systems

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The Depository Trust & Clearing Corporation (DTCC)
Senior Application Support Engineer / Site Reliability Engineer (SRE)
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The Depository Trust & Clearing Corporation (DTCC)
Added 6d ago
Senior Application Support Engineer / Site Reliability Engineer (SRE)
The Depository Trust & Clearing Corporation (DTCC)
Boston, Massachusetts
Cloud & DevOps
Technical Product & Program Management
IT Support & Systems Administration
Cybersecurity
IT Support
Hybrid
Bachelor's

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Sereact
Robotics Application Engineer
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Sereact
Added 1mo ago
Robotics Application Engineer
Sereact
Boston, Massachusetts
AI (Artificial Intelligence)
Data Science
$125k - $200k/yr

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See All 42 Application Engineer Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find Application Engineer Jobs

Application Engineer Job Market in Boston

Who's Hiring

CVS Health
CVS Health4 open roles
Ryder System
Ryder System4 open roles
Datadog
Datadog2 open roles

Top Industries Hiring

  • Manufacturing
  • Technology & Software
  • Automotive
  • Law & Legal Services
  • Distribution & Wholesale

Application Engineer Jobs in Boston: Frequently Asked Questions

How do I get an application engineer job in Boston?

Target Boston's most active hiring sectors: life sciences instrumentation, defense and aerospace systems, and enterprise software. The Seaport District and Kendall Square neighborhoods concentrate the most openings. Candidates with hands-on technical demos, solution selling experience, or a background bridging engineering and customer-facing roles stand out in this market. Tailoring your resume to the specific product type each employer builds gives you a measurable edge.

Which companies hire application engineers in Boston?

Companies currently hiring application engineers in Boston include CVS Health, Ryder System, and Datadog, per current listings on Migrate Mate as of August 2026. Boston's mix of research-intensive medical device firms, defense contractors, and B2B software companies makes it one of the more diverse application engineering markets on the East Coast.

Are there remote application engineer jobs in Boston?

Yes, though availability depends heavily on role type: positions requiring lab work, product demonstrations, or on-site customer support are rarely fully remote, while analytical and configuration-focused roles are more flexible. About 55% of application engineer openings tied to Boston are remote or hybrid as of August 2026, reflecting that split. Software and cloud-platform application engineering roles in the Seaport and Back Bay corridors tend to offer the most hybrid flexibility.

How can I get an application engineer job in Boston with little or no experience?

The most realistic entry path in Boston is through technical support or field applications associate roles at life sciences and instrumentation companies, many of which are clustered in the Kendall Square and Seaport ecosystems. Lab experience from Boston-area universities or co-op programs is valued by these employers. Roles like applications scientist, technical support engineer, or solutions consultant frequently serve as the local on-ramp before moving into a full application engineer position.

Which industries hire the most application engineers in Boston?

Boston application engineer roles concentrate in Manufacturing, Technology & Software, and Automotive, based on current listings on Migrate Mate as of August 2026. Boston's deep research and development infrastructure, anchored by its medical device ecosystem and defense technology base, drives consistent demand across those sectors year-round.

See All 42 Application Engineer Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find Application Engineer Jobs