Application Engineer Jobs in Boston, MA

Application Engineer jobs in Boston are in strong demand, concentrated in the Seaport District, Kendall Square, and Back Bay across life sciences, defense technology, and enterprise software. Employers hiring right now include Dana-Farber Cancer Institute, Klaviyo, and State Street. See the openings below and apply to the ones that match your experience.

Find Application Engineer Jobs

Overview

Open roles117+
Top employerDana-Farber Cancer Institute
Work type57% On-site
Top credentialBachelor's
Companies hiring61

Showing 5 of 117+ Application Engineer jobs

HarbourVest
Vice President, Application Architecture
We won't show you this job again
HarbourVest
Added 2d ago
Vice President, Application Architecture
HarbourVest
Boston, Massachusetts
Cloud & DevOps
Solutions Engineering & Architecture
Technical Product & Program Management
Software Engineering
Cloud Engineering
Technical Program Management
DevOps
$225k - $240k/yr
Hybrid
Bachelor's
501-1,000

Have you applied for this role?

Dana-Farber Cancer Institute
Senior IS Application Analyst
We won't show you this job again
Dana-Farber Cancer Institute
Added 3d ago
Senior IS Application Analyst
Dana-Farber Cancer Institute
Boston, Massachusetts
Business Analysis
Project & Program Management
Technical Product & Program Management
Quality Assurance & Testing (QA Testing)
Healthcare Administration
Project Management
Technical Program Management
$116k - $128k/yr
Hybrid
Bachelor's
1,001-5,000

Have you applied for this role?

Dana-Farber Cancer Institute
IS Application Analyst II - Radiation Oncology
We won't show you this job again
Dana-Farber Cancer Institute
Added 3d ago
IS Application Analyst II - Radiation Oncology
Dana-Farber Cancer Institute
Boston, Massachusetts
IT Support & Systems Administration
Customer Service & Support
Project & Program Management
IT Support
$91k - $102k/yr
High School
1,001-5,000

Have you applied for this role?

Dana-Farber Cancer Institute
Senior IS Application Analyst - Radiation Oncology
We won't show you this job again
Dana-Farber Cancer Institute
Added 3d ago
Senior IS Application Analyst - Radiation Oncology
Dana-Farber Cancer Institute
Boston, Massachusetts
Business Analysis
Project & Program Management
Technical Product & Program Management
Healthcare Administration
Project Management
Technical Program Management
$116k - $128k/yr
Certification
1,001-5,000

Have you applied for this role?

Lilt- Lega Italiana per la Lotta contro i Tumori
Android Application Engineer
We won't show you this job again
Lilt- Lega Italiana per la Lotta contro i Tumori
Added 1w ago
Android Application Engineer
Lilt- Lega Italiana per la Lotta contro i Tumori
Boston, Massachusetts
Software Engineering
Technical Product & Program Management
Mobile Engineering (iOS/Android)
Technical Program Management
$143k - $206k/yr

Have you applied for this role?

See All 117+ Application Engineer Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find Application Engineer Jobs

Application Engineer Job Market in Boston

Who's Hiring

  • Dana-Farber Cancer Institute
    Dana-Farber Cancer Institute10
  • Klaviyo
    Klaviyo9
  • State Street
    State Street7
  • Deloitte
    Deloitte6
  • Amazon Web Services
    Amazon Web Services4

Top Industries Hiring

  • Technology & Software29
  • Investment & Asset Management13
  • Consulting & Professional Services13
  • Biotechnology & Pharmaceuticals11
  • Banking & Financial Services10

Application Engineer Jobs in Boston: Frequently Asked Questions

How do I get an application engineer job in Boston?

Target Boston's most active hiring sectors: life sciences instrumentation, defense and aerospace systems, and enterprise software. The Seaport District and Kendall Square neighborhoods concentrate the most openings. Candidates with hands-on technical demos, solution selling experience, or a background bridging engineering and customer-facing roles stand out in this market. Tailoring your resume to the specific product type each employer builds gives you a measurable edge.

Which companies hire application engineers in Boston?

Companies currently hiring application engineers in Boston include Dana-Farber Cancer Institute, Klaviyo, and State Street, per current listings on Migrate Mate as of June 2026. Boston's mix of research-intensive medical device firms, defense contractors, and B2B software companies makes it one of the more diverse application engineering markets on the East Coast.

Are there remote application engineer jobs in Boston?

Yes, though availability depends heavily on role type: positions requiring lab work, product demonstrations, or on-site customer support are rarely fully remote, while analytical and configuration-focused roles are more flexible. About 43% of application engineer openings tied to Boston are remote or hybrid as of June 2026, reflecting that split. Software and cloud-platform application engineering roles in the Seaport and Back Bay corridors tend to offer the most hybrid flexibility.

How can I get an application engineer job in Boston with little or no experience?

The most realistic entry path in Boston is through technical support or field applications associate roles at life sciences and instrumentation companies, many of which are clustered in the Kendall Square and Seaport ecosystems. Lab experience from Boston-area universities or co-op programs is valued by these employers. Roles like applications scientist, technical support engineer, or solutions consultant frequently serve as the local on-ramp before moving into a full application engineer position.

Which industries hire the most application engineers in Boston?

Boston application engineer roles concentrate in Technology & Software, Investment & Asset Management, and Consulting & Professional Services, based on current listings on Migrate Mate as of June 2026. Boston's deep research and development infrastructure, anchored by its medical device ecosystem and defense technology base, drives consistent demand across those sectors year-round.

See All 117+ Application Engineer Jobs in Boston

Find roles in Boston that match your experience and apply in just a few clicks.

Find Application Engineer Jobs