Applied AI Engineer Jobs in San Francisco, CA
Applied AI Engineer jobs in San Francisco concentrate in the Financial District, SoMa, and Mission Bay, across foundation model development, enterprise AI, and applied research for tech, biotech, and fintech employers. Companies currently hiring include Anthropic, OpenAI, and Okta. Scan the live roles below and apply to whichever ones fit.
Find Applied AI Engineer JobsOverview
Showing 5 of 201+ Applied AI Engineer jobs











Our Mission
Rebuild how the world works, to make institutions work better for the people they serve.
About Brain Co.
Brain Co. builds AI-native operating systems for large, regulated institutions. Each system is built for a specific industry, powered by agents that push real workflows forward. Underneath it all is Atlas, our proprietary platform that keeps customers in control, secure by design, and never locked into one model.
Why Now
Brain Co. is entering its next phase of production deployments on a national scale with an elite team built from Palantir, Google, Meta, and Nvidia, and a growing footprint across government, insurance, health, and financial services.
Joining now means shaping both the company and a new category of applied AI. Every project here ships to production and is expected to create measurable customer value and impact.
You'll work alongside exceptional peers on some of the hardest problems in applied AI. It’s the kind of work you'll still be proud of in ten years from now.
About the Role:
As an AI/ML Engineer Intern, you’ll work alongside experienced engineers and researchers to help design, build, and deploy machine learning systems that solve high-impact problems in healthcare, government, and energy.
This internship is designed for current undergraduate students, specifically juniors and seniors graduating no later than June 2028, who want hands-on experience applying modern AI techniques, especially large language models, to real-world challenges. You’ll gain exposure to the full ML lifecycle while receiving mentorship and ownership over meaningful projects.
What You’ll Do
Assist in designing and deploying LLM-powered applications to automate complex, real-world workflows
Build and improve data pipelines and support model training, evaluation, and optimization
Work with structured and unstructured data (e.g., text, documents, logs)
Help prepare models and systems for production deployment and monitoring
Collaborate closely with senior engineers, AI researchers, and product teams
Learn best practices through code reviews, design discussions, and hands-on mentorship
Gain exposure to customer-facing and real-world constraints, including working with public-sector institutions
You Might Be a Good Fit If You
Are a current undergraduate students, specifically juniors and seniors graduating no later than June 2028, pursuing a degree in Computer Science, Machine Learning, Data Science, or a related field
Have experience programming in Python
Have coursework or project experience in machine learning or AI
Have exposure to or interest in large language models and GenAI applications (e.g., agents, RAG, reasoning workflows)
Have used or are eager to learn frameworks such as PyTorch, JAX, or TensorFlow
Have strong fundamentals in data structures and algorithms
Are curious, proactive, and excited to learn quickly in a fast-paced environmentEnjoy owning problems end-to-end with guidance and support
Internship Details & Benefits
Dates: May 31, 2027 - Aug 6, 2027 or July 5, 2027 - September 10, 2027
Competitive internship compensation
Hands-on mentorship from experienced AI engineers and researchers
Opportunity to work on real production systems used globally
Potential return-offer consideration for future internships or full-time roles
Daily lunches (if onsite)
See All 201+ Applied AI Engineer Jobs in San Francisco
Find roles in San Francisco that match your experience and apply in just a few clicks.
Find Applied AI Engineer JobsApplied AI Engineer Job Market in San Francisco
Who's Hiring
- Anthropic37

- OpenAI30

- Okta6

- MERCOR6

- David Joseph & Company6D
Top Industries Hiring
- Technology & Software18
- Science & Research6
- Consulting & Professional Services2
Applied AI Engineer Jobs in San Francisco: Frequently Asked Questions
How do I get a applied ai engineer job in San Francisco?
Focus your search on SoMa and Mission Bay, where AI-first startups and enterprise AI labs concentrate, and on the Financial District, where fintech and enterprise software companies embed applied AI teams. Candidates who demonstrate production-ready model deployment, experience with LLM fine-tuning, or a portfolio of shipped AI features move fastest in San Francisco's market. Referrals through the local AI meetup circuit carry real weight here.
Which companies hire applied ai engineers in San Francisco?
Companies currently hiring applied ai engineers in San Francisco include Anthropic, OpenAI, and Okta, per current listings on Migrate Mate as of November 2026. San Francisco's employer mix skews toward AI-native startups, foundation model labs, and large tech companies with dedicated applied research divisions, giving candidates a wide range of team sizes and product stages to consider.
Are there remote applied ai engineer jobs in San Francisco?
Yes, though roles requiring GPU cluster access, on-site inference hardware, or close collaboration with research teams often expect in-office presence. About 76% of applied ai engineer openings tied to San Francisco are remote or hybrid as of November 2026, with remote arrangements most common for inference optimization, prompt engineering, and ML platform work that runs entirely in cloud environments.
How can I get a applied ai engineer job in San Francisco with little or no experience?
The most realistic entry path is through AI-adjacent roles at San Francisco's mid-stage startups, which regularly hire ML engineers or data scientists who want to move into applied AI. Contributing to open-source LLM tooling, completing a fellowship at one of the city's AI research nonprofits, or building a public project on a well-known benchmark dataset gives hiring managers something concrete to evaluate when your work history is limited.
Which industries hire the most applied ai engineers in San Francisco?
San Francisco applied ai engineer roles concentrate in Technology & Software, Science & Research, and Consulting & Professional Services, based on current listings on Migrate Mate as of November 2026. San Francisco's density of foundation model companies, AI-integrated fintech platforms, and health-tech firms building clinical decision tools makes it one of the most active hiring markets for applied AI talent in the country.
Related Jobs in California
See All 201+ Applied AI Engineer Jobs in San Francisco
Find roles in San Francisco that match your experience and apply in just a few clicks.
Find Applied AI Engineer Jobs