Applied Scientist Jobs in San Francisco, CA

Applied Scientist jobs in San Francisco are concentrated in SoMa, Mission Bay, and the Financial District, with demand driven by AI infrastructure, biotech platforms, and enterprise software. Employers hiring right now include Pinterest, Lyft, and Socure. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles149+
Top employerPinterest
Work type51% Hybrid
Top credentialBachelor's
Companies hiring67

Showing 5 of 149+ Applied Scientist jobs

Amazon.com
Applied Scientist II
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Amazon.com
Added 1d ago
Applied Scientist II
Amazon.com
San Francisco, California
On-Site
Doctorate
10,000+

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N
Senior Applied AI/ML Scientist
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N
Added 3d ago
Senior Applied AI/ML Scientist
NobleAI
San Francisco, California
Software Engineering
Data Science & Analytics
Data Engineering
Cybersecurity
AI (Artificial Intelligence)
ML (Machine Learning)
Data Science
$190k - $220k/yr
Remote (US)
Doctoral degree in chemistry

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Amazon.com
Senior Applied Scientist
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Amazon.com
Added 1w ago
Senior Applied Scientist
Amazon.com
San Francisco, California
Data Science & Analytics
Software Engineering
Data Science
AI (Artificial Intelligence)
ML (Machine Learning)
$192k - $260k/yr
Doctoral degree in Computer Science
10,000+

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Genentech
Machine Learning Scientist/Senior Machine Learning Scientist - Agents for Applied Small Molecule Drug Design, AI for Drug Discovery
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Genentech
Added 1w ago
Machine Learning Scientist/Senior Machine Learning Scientist - Agents for Applied Small Molecule Drug Design, AI for Drug Discovery
Genentech
San Francisco, California
Software Engineering
Data Science & Analytics
AI (Artificial Intelligence)
ML (Machine Learning)
Data Science
$148k - $297k/yr
Doctoral degree in Computer Science
10,000+

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Amazon.com
Applied Scientist, Navigation
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Amazon.com
Added 1w ago
Applied Scientist, Navigation
Amazon.com
San Francisco, California
Software Engineering
Data Science & Analytics
Specialized Engineering
AI (Artificial Intelligence)
ML (Machine Learning)
Data Science
Robotics Engineering
$143k - $222k/yr
Doctoral degree in Computer Science
10,000+

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See All 149+ Applied Scientist Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

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Applied Scientist Job Market in San Francisco

Who's Hiring

  • Pinterest
    Pinterest13
  • Lyft
    Lyft8
  • Socure
    Socure7
  • Whatnot
    Whatnot7
  • Amazon
    Amazon7

Top Industries Hiring

  • Technology & Software92
  • Retail14
  • E-Commerce & Online Marketplaces13
  • Science & Research8
  • Fintech6

Applied Scientist Jobs in San Francisco: Frequently Asked Questions

How do I get a applied scientist job in San Francisco?

Focus your search on San Francisco's three strongest hiring clusters: AI and machine learning platforms in SoMa, biotech and computational biology firms in Mission Bay, and fintech and data infrastructure companies in the Financial District. Candidates who can demonstrate production ML experience, published research, or strong open-source contributions stand out in this market. Targeting mid-stage startups alongside large tech employers broadens your options considerably.

Which companies hire applied scientists in San Francisco?

Employers hiring applied scientists in San Francisco right now include Pinterest, Lyft, and Socure, based on current listings on Migrate Mate as of June 2026. San Francisco's hiring mix skews toward AI-native startups, established tech platforms, and life sciences companies with computational research arms.

Are there remote applied scientist jobs in San Francisco?

Yes, though it depends heavily on the role: purely analytical and modeling work is frequently remote, while positions involving lab systems, on-site data infrastructure, or embedded product teams tend to require in-person presence. About 63% of applied scientist openings tied to San Francisco are remote or hybrid as of June 2026. The most remote-friendly specialties locally are NLP, recommendation systems, and forecasting.

How can I get a applied scientist job in San Francisco with little or no experience?

The most realistic entry path in San Francisco is through a research engineering or junior ML engineer role at a mid-stage startup, where scope is broader and teams are smaller. AI-focused companies in SoMa and Mission Bay frequently hire candidates with strong graduate research backgrounds even without industry experience. Contributing to open-source projects used by San Francisco employers and attending local ML meetups builds visibility with hiring managers directly.

Which industries hire the most applied scientists in San Francisco?

Most applied scientist openings in San Francisco sit in Technology & Software, Retail, and E-Commerce & Online Marketplaces, per current listings on Migrate Mate as of June 2026. San Francisco's density of AI-first companies, biotech research platforms, and fintech infrastructure firms creates sustained demand for applied scientists with specialized modeling and experimentation skills.

See All 149+ Applied Scientist Jobs in San Francisco

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