Applied Scientist Jobs in San Francisco, CA

Applied Scientist jobs in San Francisco are concentrated in SoMa, Mission Bay, and the Financial District, with demand driven by AI infrastructure, biotech platforms, and enterprise software. Employers hiring right now include Amazon, Amazon Web Services, and Lyft. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles134+
Top employerAmazon
Work type64% Hybrid
Top credentialMaster's degree
Companies hiring18

Showing 5 of 134+ Applied Scientist jobs

Applied AI Scientist
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Added 2w ago
Applied AI Scientist
David Joseph & Company
San Francisco, California
Clinical Trials
Laboratory Research
Research & Academia
$170k - $300k/yr
Bachelor's degree

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Applied Scientist, Center for Quantum Computing, Physical Design and Simulation
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Added 2w ago
Applied Scientist, Center for Quantum Computing, Physical Design and Simulation
Amazon Web Services
San Francisco, California
Biotech & Life Sciences
Environmental & Physical Sciences
Laboratory Research
Research & Academia
$172k - $222k/yr
Doctoral degree in Computer Science

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Applied Scientist, Amazon Ads
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Added 2w ago
Applied Scientist, Amazon Ads
Amazon.com
San Francisco, California
Biotech & Life Sciences
Environmental & Physical Sciences
Laboratory Research
Research & Academia
$172k - $222k/yr
Master's degree
10,000+

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Applied Scientist
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Added 3w ago
Applied Scientist
Twitch
San Francisco, California
AI (Artificial Intelligence)
Data Science
ML (Machine Learning)
Software Engineering
$172k - $222k/yr
Bachelor's degree in Physics
1,001-5,000

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Applied Scientist
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Added 3w ago
Applied Scientist
Amazon.com
San Francisco, California
Engineering (Non-Software)
Software Engineering
Technical Program Management
$172k - $222k/yr
Bachelor's degree in Physics
10,000+

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See All 134+ Applied Scientist Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

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Applied Scientist Job Market in San Francisco

Who's Hiring

  • Amazon29
  • Amazon Web Services19
  • Lyft10
  • SentiLink10
  • Braze5

Top Industries Hiring

  • Technology & Software34
  • Retail5
  • E-Commerce & Online Marketplaces5

Applied Scientist Jobs in San Francisco: Frequently Asked Questions

How do I get a applied scientist job in San Francisco?

Focus your search on San Francisco's three strongest hiring clusters: AI and machine learning platforms in SoMa, biotech and computational biology firms in Mission Bay, and fintech and data infrastructure companies in the Financial District. Candidates who can demonstrate production ML experience, published research, or strong open-source contributions stand out in this market. Targeting mid-stage startups alongside large tech employers broadens your options considerably.

Which companies hire applied scientists in San Francisco?

Employers hiring applied scientists in San Francisco right now include Amazon, Amazon Web Services, and Lyft, based on current listings on Migrate Mate as of November 2026. San Francisco's hiring mix skews toward AI-native startups, established tech platforms, and life sciences companies with computational research arms.

Are there remote applied scientist jobs in San Francisco?

Yes, though it depends heavily on the role: purely analytical and modeling work is frequently remote, while positions involving lab systems, on-site data infrastructure, or embedded product teams tend to require in-person presence. About 85% of applied scientist openings tied to San Francisco are remote or hybrid as of November 2026. The most remote-friendly specialties locally are NLP, recommendation systems, and forecasting.

How can I get a applied scientist job in San Francisco with little or no experience?

The most realistic entry path in San Francisco is through a research engineering or junior ML engineer role at a mid-stage startup, where scope is broader and teams are smaller. AI-focused companies in SoMa and Mission Bay frequently hire candidates with strong graduate research backgrounds even without industry experience. Contributing to open-source projects used by San Francisco employers and attending local ML meetups builds visibility with hiring managers directly.

Which industries hire the most applied scientists in San Francisco?

Most applied scientist openings in San Francisco sit in Technology & Software, Retail, and E-Commerce & Online Marketplaces, per current listings on Migrate Mate as of November 2026. San Francisco's density of AI-first companies, biotech research platforms, and fintech infrastructure firms creates sustained demand for applied scientists with specialized modeling and experimentation skills.

See All 134+ Applied Scientist Jobs in San Francisco

Find roles in San Francisco that match your experience and apply in just a few clicks.

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