Laboratory Supervisor Jobs in California

Laboratory Supervisor jobs in California are among the most active in the country, concentrated in biotechnology, clinical diagnostics, pharmaceutical manufacturing, and environmental testing across a workforce that ranges from bench-level leads to senior lab directors. The largest hiring metros are the San Francisco Bay Area, San Diego, and Los Angeles, where employers like Quest Diagnostics, Thermo Fisher Scientific, and Kaiser Permanente maintain deep and ongoing staffing needs. The most in-demand specialties are clinical laboratory science, quality control oversight, and bioanalytical testing. Find a role that fits below and apply directly.

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Overview

Open roles30
Top employerCommonSpirit Health
Top citySan Diego, CA
Cities hiring23
Work type100% On-site
Top industryBiotechnology

Showing 5 of 30+ Laboratory Supervisor jobs

Laboratory Supervisor - Clinical Laboratory - Full Time/Days - Req#2185052093
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Added 4d ago
Laboratory Supervisor - Clinical Laboratory - Full Time/Days - Req#2185052093
Antelope Valley Medical Center
Lancaster, California
Customer Service
Healthcare Administration
Human Resources
$133k - $195k.41/yr
Bachelor's degree
1,001-5,000

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QC Laboratory Supervisor- MLT
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Added 5d ago
QC Laboratory Supervisor- MLT
American Red Cross
San Leandro, California
Business Operations
Customer Service
Customer Success
10,000+

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Facility Supervisor (Laboratory Animal Facility)
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Added 1w ago
Facility Supervisor (Laboratory Animal Facility)
Charles River Laboratories
South San Francisco, California
Biotech & Life Sciences
Environmental & Physical Sciences
Laboratory Research
Research & Academia
$85k - $95k/yr
Bachelor of Science
10,000+

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Microbiology Clinical Laboratory Supervisor - Hospital
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Added 1w ago
Microbiology Clinical Laboratory Supervisor - Hospital
County of Ventura Government
Santa Paula, California
Clinical Trials
Data Science
Project Management
$114k.67 - $152k.12/yr

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Laboratory Supervisor
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Added 1w ago
Laboratory Supervisor
California Water Service Group (CWSG)
Commerce, California
Compliance & Legal
IT Support
Project Management
Technical Program Management
$92k - $171k/yr
On-Site
Bachelor's degree in biology

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See All 30 Laboratory Supervisor Jobs in California

Find roles in California that match your experience and apply in just a few clicks.

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Laboratory Supervisor Jobs by City in California

Where California roles are concentrated, by current openings.

San Diego
3 jobs
Los Angeles
3 jobs
Downey
2 jobs
Aliso Viejo
2 jobs
Redwood City
2 jobs
Arvin
1 job
Indio
1 job
Acampo
1 job
Modesto
1 job

Laboratory Supervisor Job Market in California

A snapshot from current California openings, updated as new roles post.

Who's Hiring

CommonSpirit Health3 open roles
Abbott2 open roles
NeoGenomics2 open roles

Top Industries Hiring

  • Biotechnology & Pharmaceuticals

What California Employers Look For

The qualifications that appear most often in laboratory supervisor jobs across California.

  • California Clinical Laboratory Scientist license issued by the California Department of Public Health required for clinical roles
  • Bachelor's degree in medical laboratory science, biology, chemistry, or a closely related field
  • Minimum two years of bench laboratory experience in the relevant discipline
  • Demonstrated supervisory or lead experience overseeing laboratory staff and daily operations
  • Proficiency with laboratory information systems and quality management documentation
  • Knowledge of CAP, CLIA, and California Title 17 regulatory compliance standards

Laboratory Supervisor Jobs in California: Frequently Asked Questions

How do you become a laboratory supervisor in California?

The most direct path in California is earning a California Clinical Laboratory Scientist license through the California Department of Public Health, which requires a bachelor's degree in a life science or medical laboratory science field, completion of an accredited training program, and passing the CLS licensure exam. Supervisory roles in clinical settings typically require this credential plus documented bench experience. For non-clinical laboratory environments such as environmental or industrial labs, the licensing requirement does not apply, but a relevant science degree and field experience remain standard.

How much do laboratory supervisors make in California?

Laboratory supervisors in California earn a median of about $210,230 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $130,730 for the lowest 10% to over $330,050 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire laboratory supervisors in California?

Employers hiring laboratory supervisors in California right now include CommonSpirit Health, Abbott, and NeoGenomics, based on current listings on Migrate Mate as of November 2026. California's concentration of biotech firms, hospital networks, and contract research organizations means demand is spread across both large anchor institutions and mid-sized specialty laboratories.

Which California cities have the most laboratory supervisor jobs?

San Diego, Los Angeles, and Downey have the most laboratory supervisor openings in California. The Bay Area leads due to its dense cluster of biotechnology headquarters and research institutions, San Diego draws heavily from pharmaceutical and genomics companies, and Los Angeles reflects demand from large hospital systems and public health labs spread throughout Southern California.

Are there remote laboratory supervisor jobs in California?

Yes, but they're rare. Laboratory supervisor work is inherently hands-on, requiring on-site oversight of staff, equipment, and specimens. About 0% of laboratory supervisor openings tied to California are remote or hybrid as of November 2026, and most of those involve administrative functions such as quality assurance review, regulatory documentation, or training coordination rather than direct bench management.

How can I get hired as a laboratory supervisor in California with little or no experience?

The most realistic entry path is securing a staff-level laboratory scientist position first, then progressing internally into a lead or supervisor role. Large California hospital systems such as Kaiser Permanente and academic medical centers affiliated with the University of California campuses regularly run new-graduate CLS training programs. Moving laterally from roles like laboratory technician, quality control analyst, or research associate builds the supervisory case. Holding an active California CLS license significantly strengthens a candidate's standing even at the entry level.

Where can I find and apply to laboratory supervisor jobs in California?

You can find and apply to laboratory supervisor jobs in California on Migrate Mate, which lists current California openings. Find roles that fit your experience and specialty, then apply directly to the employers posting them.

See All 30 Laboratory Supervisor Jobs in California

Find roles in California that match your experience and apply in just a few clicks.

Find Laboratory Supervisor Jobs