Laboratory Supervisor Jobs in Pennsylvania
Laboratory Supervisor jobs in Pennsylvania are consistently active, with strong demand concentrated in clinical diagnostics, pharmaceutical manufacturing, and environmental testing across roles from bench-level team leads through senior laboratory directors. Philadelphia, Pittsburgh, and Allentown account for the largest share of openings, anchored by employers such as Quest Diagnostics, Penn Medicine, and Merck. The most in-demand specialties are clinical laboratory oversight, quality control supervision in biopharma, and environmental compliance lab management. Find a role that fits below and apply directly.
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Castle Biosciences Earns "Top Workplaces USA Award" for Phoenix, Pittsburgh, and Friendswood!
Learn more at www.CastleBiosciences.com
Castle Biosciences Inc. is growing, and we are looking to hire a full-time Laboratory Supervisor working from our Pittsburgh, PA laboratory location, with a start date of December 1, 2026.
Why Castle Biosciences?
Exceptional Benefits Package:
- Excellent Annual Salary + 25% Bonus Potential
- This role is eligible for differential pay of $4,000/year subject to change based on schedule changes.
- 20 Accrued PTO Days Annually + 10 Paid Holidays
- 401K with 100% Company Match up to 6%
- 3 Health Care Plan Options + Company HSA Contribution
- Company Stock Grant Upon Hire
- Castle offers company‑paid, secure garage parking with direct building access, available whenever you're downtown or visiting local attractions.
A DAY IN THE LIFE OF A Laboratory Supervisor
This position supports the clinical laboratory's daily oversight by promoting efficient workflows, providing coaching, and addressing troubleshooting and issue resolution as they arise. The individual serves as a key communication link between laboratory staff and upper management while offering ongoing support to the laboratory team. The supervisor ensures all procedures are performed in accordance with established scientific methodologies and specialized analytical techniques, maintaining full compliance with applicable regulatory standards. Primary responsibilities include supervising day-to-day laboratory operations, ensuring adherence to quality management system policies and procedures, monitoring employee productivity, and providing guidance and coaching to support performance and operational excellence.
REQUIRED QUALIFICATIONS
- Minimum of a bachelor's degree in science related field
- Minimum of 3+ years in a clinical laboratory, with 1 (CAP) years' experience in high complexity molecular testing (CAP).
- Proven experience as Supervisor or similar management role preferred.
- Please see the full job description at the end of the job ad.
SCHEDULE
- Monday through Friday, 12:30 pm to 9 pm, exempt position, working from the Pittsburgh, PA laboratory.
- The role may require flexibility to meet operational needs.
READY TO JOIN OUR BIOTECH TEAM?
We truly appreciate your time. If this feels like the right opportunity for you, we'd love for you to complete our mobile-friendly application. We're excited to learn more about you and look forward to connecting soon!
Castle Biosciences Awards and Research Developments!
WORK AUTHORIZATION
All candidates must be legally authorized to work in the United States. Currently, Castle Biosciences does not sponsor H-1B visas, OPT, or employment-related visas.
ABOUT CASTLE BIOSCIENCES INC.
At Castle, it all comes down to people. After all, disease doesn't just happen - it happens to people. We believe that disease management and treatment decisions can be better informed through a person's unique biology, which is revealed through the scientific rigor of our innovative, laboratory-developed tests. We are committed to empowering healthcare providers and patients with the goal of improved outcomes.
Every employee at Castle has an impact on patient care, and we work to ensure that everyone finds their work to be both challenging and rewarding. We behave with integrity and treat our colleagues with respect and kindness. Our culture fosters an environment of trust, transparency, and collaboration. We prioritize and encourage internal growth and professional development.
Castle Biosciences is an equal opportunity employer as to all protected groups, including protected veterans and individuals with disabilities.
If you have a disability and you believe you need a reasonable accommodation in order to search for a job opening or to submit an online application, please e-mail ReasonableAccommodationsRequest@castlebiosciences.com.
This email was created exclusively to assist disabled job seekers whose disability prevents them from being able to apply online. Only messages left for this purpose will be returned. Messages left for other purposes, such as following up on an application or technical issues not related to a disability, will not receive a response.
** No third-party recruiters, please
See All 12 Laboratory Supervisor Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Laboratory Supervisor JobsLaboratory Supervisor Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Laboratory Supervisor Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
What Pennsylvania Employers Look For
The qualifications that appear most often in laboratory supervisor jobs across Pennsylvania.
- Active Pennsylvania clinical laboratory director or supervisor certification where required by the Pennsylvania Department of Health
- Bachelor's degree in medical laboratory science, chemistry, biology, or a closely related field
- Minimum years of hands-on bench experience in a clinical, pharmaceutical, or environmental laboratory setting
- Demonstrated experience supervising laboratory staff, scheduling, and conducting performance evaluations
- Proficiency with laboratory information systems and quality management documentation processes
- Knowledge of CLIA, CAP, or ISO 17025 accreditation standards and regulatory compliance requirements
Laboratory Supervisor Jobs in Pennsylvania: Frequently Asked Questions
How do you become a laboratory supervisor in Pennsylvania?
Most laboratory supervisor roles in Pennsylvania require a bachelor's degree in medical laboratory science, chemistry, or a related discipline, followed by documented bench experience in your specialty. For clinical laboratory positions, the Pennsylvania Department of Health oversees laboratory director and supervisor qualifications under state clinical laboratory law, and many employers require American Society for Clinical Pathology board certification. Pharmaceutical and environmental lab roles emphasize relevant industry credentials and quality system experience over state licensure.
How much do laboratory supervisors make in Pennsylvania?
Laboratory supervisors in Pennsylvania earn a median of about $137,900 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $59,040 for the lowest 10% to over $312,510 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire laboratory supervisors in Pennsylvania?
Employers hiring laboratory supervisors in Pennsylvania right now include Penn Medicine, Penn State Health, and UPMC, based on current listings on Migrate Mate as of November 2026. Pennsylvania's concentration of health systems, biopharma manufacturers along the Route 202 corridor, and environmental testing firms creates ongoing supervisor demand across multiple laboratory disciplines.
Which Pennsylvania cities have the most laboratory supervisor jobs?
Pittsburgh, Philadelphia, and Pennsylvania hold the most laboratory supervisor openings in Pennsylvania. Philadelphia dominates because of its dense cluster of academic medical centers, large health systems, and major pharmaceutical campuses, while Pittsburgh's university hospitals and life sciences sector drive consistent demand, and Allentown's growing healthcare corridor adds volume in the Lehigh Valley region.
How can I get hired as a laboratory supervisor in Pennsylvania with little or no experience?
The most realistic entry path is moving from a senior medical laboratory scientist or lead technologist role into a supervisory title within the same department. Large Pennsylvania health systems such as Penn Medicine, UPMC, and Jefferson Health regularly post internal promotions and sometimes accept external candidates with ASCP certification and demonstrated leadership on a team. Pursuing a laboratory management certificate through a Pennsylvania community college or professional association strengthens a resume when direct supervisory years are limited.
Where can I find and apply to laboratory supervisor jobs in Pennsylvania?
You can find and apply to laboratory supervisor jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings across clinical, pharmaceutical, and environmental settings. Find the roles that fit your specialty and experience level and apply directly through each listing.
See All 12 Laboratory Supervisor Jobs in Pennsylvania
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