Senior Level Clinical Lead Jobs
Senior level clinical lead jobs place experienced clinicians in charge of care standards, team oversight, and the outcomes that define a program's quality. Roles are concentrated across Biotechnology & Pharmaceuticals, Insurance, and Non-Profit & Social Services, with a mix of on-site, hybrid, and remote positions available and employers like American Heart Association, CVS Health, and Revolution Medicines hiring at this level now.
Find JobsOverview
Showing 5 of 32+ Senior Level Clinical Lead jobs
INTRODUCTION
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
About Us
Mass General Brigham (MGB) is a not-for-profit, integrated healthcare system committed to advancing patient care, research, education, and service. Founded by Brigham and Women’s Hospital and Massachusetts General Hospital, MGB supports a comprehensive continuum of care, including community and specialty hospitals, physician networks, and research programs.
We are guided by a people-first culture grounded in core values including patient care, innovation, collaboration, and continuous improvement.
ROLE OVERVIEW
The Enterprise Digital System Clinical Lead – Pathology provides clinical informatics leadership for Epic systems supporting laboratory (Beaker – AP/CP) and non-laboratory clinical workflows related to pathology across ambulatory and inpatient settings. This role is responsible for ensuring safe, efficient, and standardized workflows across the full lifecycle of pathology services, including ordering, specimen collection, processing, result management, and downstream clinical workflows, spanning Epic Beaker and integrated Epic modules. The role includes ownership of highly variable and cross-setting workflows, including ambulatory, inpatient, procedural, and specialty diagnostic pathways, requiring coordination across clinical care teams, laboratory operations, and external partners. This position is approximately 40% informatics effort, with the remainder dedicated to clinical, academic, or research responsibilities.
KEY RESPONSIBILITIES
Clinical Informatics Leadership
- Serve as the Epic informatics lead for Clinical and Anatomic Pathology workflows across ambulatory and inpatient settings
- Ensure alignment of Epic solutions with clinical best practices, patient safety standards, and regulatory requirements
- Maintain awareness of Epic capabilities, system updates, and future roadmap
Workflow Design & Optimization
Lead the design, standardization, and continuous improvement of end-to-end pathology workflows, including but not limited to:
Ambulatory (Outpatient) Workflows
- In-clinic point-of-care (POC) and lab-performed testing
- In-clinic specimen collection with:
- Direct send to external laboratories (e.g., Quest, Cologuard)
- Send to MGB laboratory network
- Provider orders for:
- Lab draw encounters (phlebotomy workflows)
- Future collection tied to procedures (OB, IR, OR, cardiology, etc.)
- Home health / remote collection workflows
- Ambulatory result management workflows, including:
- Critical result notification
- Result routing to appropriate providers and care teams
Inpatient Workflows
- Point-of-care testing within inpatient units
- Specimen collection models, including:
- Nurse-collected (serum and non-serum)
- Lab-collected (phlebotomy workflows)
- Non-serum collections (e.g., tissue, fluids)
- Timed and recurring lab draws
- Orders supporting:
- Future procedure-based collections (OB, IR, OR, cardiology, etc.)
- Intra-procedural and intraoperative collections, including specimen navigator workflows and pre-placed orders
- Inpatient result management workflows, including:
- Critical result notification
- Result routing and follow-up
Complex & Specialty Workflows
- Design and optimization of specialized diagnostic and multi-step workflows, including:
- Bone marrow and hematopathology workflows
- Perinatal and fetal pathology workflows
- Other complex, multi-stage diagnostic pathways requiring coordination across teams
- Translate clinical, operational, and regulatory needs into clearly defined functional and technical requirements
- Standardize workflows across sites while accommodating necessary clinical variation
- Identify and mitigate safety risks, inefficiencies, and workflow fragmentation
Strategy, Governance & Prioritization
- Partner with the CMIO, pathology leadership, and digital teams to:
- Define enterprise strategy for pathology informatics
- Establish governance and prioritization frameworks across Epic initiatives
- Develop and maintain a multi-year roadmap aligned with organizational goals
Stakeholder Engagement & Change Management
- Build strong relationships across clinicians, lab leadership, operations, and IT
- Identify pain points across ambulatory, inpatient, and procedural workflows
- Drive consensus and standardization across diverse clinical and operational environments
- Lead change management efforts and partner with training teams to support adoption
Program & Project Execution
- Lead multidisciplinary project teams and design/build sessions
- Collaborate closely with Epic application teams and digital portfolio leadership
- Ensure delivery of scalable, reliable, and sustainable solutions
Quality Improvement & Innovation
- Use data and analytics to evaluate workflow performance and outcomes
- Drive continuous improvement in lab and clinical workflows
- Stay current on emerging best practices in clinical informatics and digital health
Collaboration & Thought Leadership
- Partner across enterprise clinical and digital domains
- Contribute to informatics education, innovation, and professional development
- Mentor and support informatics team members
QUALIFICATIONS
Required
- MD, PhD, or equivalent clinical or laboratory leadership background
- Active clinical licensure and practice
- Experience in clinical informatics and workflow optimization
- Demonstrated experience managing complex, cross-functional initiatives
- Strong understanding of pathology and laboratory workflows across care settings
- Experience with stakeholder engagement, governance, and change management
Preferred
- Epic experience (Beaker or related modules); certification preferred or willingness to obtain
- Board certification or eligibility in Clinical Informatics (for physicians)
- Experience with analytics, reporting, and performance measurement
Key Competencies
- Strategic mindset with strong execution capability
- Ability to manage complexity across multiple clinical environments
- Strong collaboration and consensus-building skills
- Clear and effective communicator across clinical and technical audiences
- Results-oriented and improvement-driven
Work Environment
- Hybrid (remote and in-person)
- Clinical practice within an MGB-affiliated site
ADDITIONAL JOB DETAILS (IF APPLICABLE)
The salary range for this position is dependent upon experience and specialty. At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience, education, certifications, and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package.
In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums, and bonuses as applicable, along with recognition programs designed to celebrate your contributions and support your professional growth. We invite candidates to apply, and our Talent Acquisition team will provide an overview of their potential compensation and benefits package.
Remote Type
Hybrid
Work Location
399 Revolution Drive
Scheduled Weekly Hours
16
Employee Type
Regular
Work Shift
Day (United States of America)
EEO STATEMENT:
Mass General Brigham Incorporated is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
INTRODUCTION
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
About Us
Mass General Brigham (MGB) is a not-for-profit, integrated healthcare system committed to advancing patient care, research, education, and service. Founded by Brigham and Women’s Hospital and Massachusetts General Hospital, MGB supports a comprehensive continuum of care, including community and specialty hospitals, physician networks, and research programs.
We are guided by a people-first culture grounded in core values including patient care, innovation, collaboration, and continuous improvement.
ROLE OVERVIEW
The Enterprise Digital System Clinical Lead – Pathology provides clinical informatics leadership for Epic systems supporting laboratory (Beaker – AP/CP) and non-laboratory clinical workflows related to pathology across ambulatory and inpatient settings. This role is responsible for ensuring safe, efficient, and standardized workflows across the full lifecycle of pathology services, including ordering, specimen collection, processing, result management, and downstream clinical workflows, spanning Epic Beaker and integrated Epic modules. The role includes ownership of highly variable and cross-setting workflows, including ambulatory, inpatient, procedural, and specialty diagnostic pathways, requiring coordination across clinical care teams, laboratory operations, and external partners. This position is approximately 40% informatics effort, with the remainder dedicated to clinical, academic, or research responsibilities.
KEY RESPONSIBILITIES
Clinical Informatics Leadership
- Serve as the Epic informatics lead for Clinical and Anatomic Pathology workflows across ambulatory and inpatient settings
- Ensure alignment of Epic solutions with clinical best practices, patient safety standards, and regulatory requirements
- Maintain awareness of Epic capabilities, system updates, and future roadmap
Workflow Design & Optimization
Lead the design, standardization, and continuous improvement of end-to-end pathology workflows, including but not limited to:
Ambulatory (Outpatient) Workflows
- In-clinic point-of-care (POC) and lab-performed testing
- In-clinic specimen collection with:
- Direct send to external laboratories (e.g., Quest, Cologuard)
- Send to MGB laboratory network
- Provider orders for:
- Lab draw encounters (phlebotomy workflows)
- Future collection tied to procedures (OB, IR, OR, cardiology, etc.)
- Home health / remote collection workflows
- Ambulatory result management workflows, including:
- Critical result notification
- Result routing to appropriate providers and care teams
Inpatient Workflows
- Point-of-care testing within inpatient units
- Specimen collection models, including:
- Nurse-collected (serum and non-serum)
- Lab-collected (phlebotomy workflows)
- Non-serum collections (e.g., tissue, fluids)
- Timed and recurring lab draws
- Orders supporting:
- Future procedure-based collections (OB, IR, OR, cardiology, etc.)
- Intra-procedural and intraoperative collections, including specimen navigator workflows and pre-placed orders
- Inpatient result management workflows, including:
- Critical result notification
- Result routing and follow-up
Complex & Specialty Workflows
- Design and optimization of specialized diagnostic and multi-step workflows, including:
- Bone marrow and hematopathology workflows
- Perinatal and fetal pathology workflows
- Other complex, multi-stage diagnostic pathways requiring coordination across teams
- Translate clinical, operational, and regulatory needs into clearly defined functional and technical requirements
- Standardize workflows across sites while accommodating necessary clinical variation
- Identify and mitigate safety risks, inefficiencies, and workflow fragmentation
Strategy, Governance & Prioritization
- Partner with the CMIO, pathology leadership, and digital teams to:
- Define enterprise strategy for pathology informatics
- Establish governance and prioritization frameworks across Epic initiatives
- Develop and maintain a multi-year roadmap aligned with organizational goals
Stakeholder Engagement & Change Management
- Build strong relationships across clinicians, lab leadership, operations, and IT
- Identify pain points across ambulatory, inpatient, and procedural workflows
- Drive consensus and standardization across diverse clinical and operational environments
- Lead change management efforts and partner with training teams to support adoption
Program & Project Execution
- Lead multidisciplinary project teams and design/build sessions
- Collaborate closely with Epic application teams and digital portfolio leadership
- Ensure delivery of scalable, reliable, and sustainable solutions
Quality Improvement & Innovation
- Use data and analytics to evaluate workflow performance and outcomes
- Drive continuous improvement in lab and clinical workflows
- Stay current on emerging best practices in clinical informatics and digital health
Collaboration & Thought Leadership
- Partner across enterprise clinical and digital domains
- Contribute to informatics education, innovation, and professional development
- Mentor and support informatics team members
QUALIFICATIONS
Required
- MD, PhD, or equivalent clinical or laboratory leadership background
- Active clinical licensure and practice
- Experience in clinical informatics and workflow optimization
- Demonstrated experience managing complex, cross-functional initiatives
- Strong understanding of pathology and laboratory workflows across care settings
- Experience with stakeholder engagement, governance, and change management
Preferred
- Epic experience (Beaker or related modules); certification preferred or willingness to obtain
- Board certification or eligibility in Clinical Informatics (for physicians)
- Experience with analytics, reporting, and performance measurement
Key Competencies
- Strategic mindset with strong execution capability
- Ability to manage complexity across multiple clinical environments
- Strong collaboration and consensus-building skills
- Clear and effective communicator across clinical and technical audiences
- Results-oriented and improvement-driven
Work Environment
- Hybrid (remote and in-person)
- Clinical practice within an MGB-affiliated site
ADDITIONAL JOB DETAILS (IF APPLICABLE)
The salary range for this position is dependent upon experience and specialty. At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience, education, certifications, and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package.
In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums, and bonuses as applicable, along with recognition programs designed to celebrate your contributions and support your professional growth. We invite candidates to apply, and our Talent Acquisition team will provide an overview of their potential compensation and benefits package.
Remote Type
Hybrid
Work Location
399 Revolution Drive
Scheduled Weekly Hours
16
Employee Type
Regular
Work Shift
Day (United States of America)
EEO STATEMENT:
Mass General Brigham Incorporated is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
See All 32 Senior Level Clinical Lead Jobs
Find roles that match your experience and apply in just a few clicks.
Find JobsSenior Level Clinical Lead Job Market
Who's Hiring
Top Industries Hiring
- Biotechnology & Pharmaceuticals
- Insurance
- Non-Profit & Social Services
- Healthcare & Medical Services
- Education
Senior Level Clinical Lead Jobs: Frequently Asked Questions
How do I get a senior level clinical lead job?
Employers hiring at this level want candidates who have already owned clinical quality initiatives, led multidisciplinary teams, and influenced policy or protocol development. Highlight experiences where you set direction rather than followed it, demonstrate measurable outcomes tied to your leadership, and show you have mentored or developed other clinicians. A history of cross-functional collaboration and regulatory or accreditation experience gives candidates a clear edge.
Which companies hire senior level clinical leads?
Companies hiring senior level clinical leads right now include American Heart Association, CVS Health, and Revolution Medicines, based on current listings on Migrate Mate as of August 2026. Hiring at this level comes from health systems, specialty care organizations, managed care companies, and healthcare consulting firms that need experienced clinicians to lead programs and drive quality outcomes.
Are there remote senior level clinical lead jobs?
Yes, though availability depends on the specific role and care setting. About 50% of senior level clinical lead openings are remote or hybrid as of August 2026, with fully remote positions more common in utilization management, care coordination, telehealth, and population health than in hands-on clinical environments that require on-site presence.
What makes a clinical lead role senior level?
Senior level clinical lead roles carry broader scope and deeper accountability than mid-level positions. At this stage, you own program-wide outcomes rather than individual cases, set clinical standards rather than follow them, and lead other clinicians rather than work alongside them. Expect responsibility for quality metrics, regulatory compliance, staff development, and strategic input into how care is designed and delivered.
Which industries hire the most senior level clinical leads?
Senior Level clinical lead roles concentrate in Biotechnology & Pharmaceuticals, Insurance, and Non-Profit & Social Services, based on current listings on Migrate Mate as of August 2026. These sectors drive hiring because they operate complex, regulated care environments that require experienced clinical leaders to maintain quality standards, manage teams, and meet accreditation requirements at scale.