Clinical Nurse Jobs in San Diego, CA

Clinical Nurse jobs in San Diego are in strong demand, concentrated in Mission Valley, Kearny Mesa, and the medical corridor around Hillcrest and Balboa Park, across hospital systems, outpatient clinics, and specialty care centers. Employers hiring right now include Sharp HealthCare, UC San Diego Health, and Rady Children's Hospital. Find a role that fits below and apply directly.

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Overview

Open roles318+
Top employerSharp HealthCare
Work type100% Hybrid
Top credentialBLS Certification
Companies hiring9

Showing 5 of 318+ Clinical Nurse jobs

Clinical Nurse - RN - Women's Recovery (PACU) - Sharp Mary Birch - Night shift - Full-time 0.9 FTE
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Added 6d ago
Clinical Nurse - RN - Women's Recovery (PACU) - Sharp Mary Birch - Night shift - Full-time 0.9 FTE
Sharp HealthCare
San Diego, California
Corporate Training
Corporate Training & Learning Development
Learning & Development
$64 - $93/hr
NRP Certification
10,000+

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Clinical Nurse Educator
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Added 6d ago
Clinical Nurse Educator
Modena Allergy + Asthma
San Diego, California
Healthcare Administration
Nursing
Patient Services & Wellbeing
Bachelor of Science

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Home Health Registered Nurse Clinical Manager - RNCM
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Added 1w ago
Home Health Registered Nurse Clinical Manager - RNCM
Lorian Health
San Diego, California
Business Development
Customer Success
Program Management
Project Management
$135k - $145k/yr
Managed Registered Nurses (RNs)
201-500

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Clinical Nurse - Infusion - Outpatient Pavillion - FT - 10Hr Days
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Added 1w ago
Clinical Nurse - Infusion - Outpatient Pavillion - FT - 10Hr Days
Sharp HealthCare
San Diego, California
Healthcare Administration
Nursing
Patient Services & Wellbeing
$64.21 - $93.76/hr
BLS Certification
10,000+

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Clinical Nurse Specialist - Operating Room
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Added 1w ago
Clinical Nurse Specialist - Operating Room
Rady Children's Hospital
San Diego, California
Clinical Support
Consulting & Professional Services
Healthcare Administration
$64.37 - $88.51/hr
NRP Certification
5,001-10,000

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See All 318+ Clinical Nurse Jobs in San Diego

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Clinical Nurse Job Market in San Diego

Who's Hiring

  • Sharp HealthCare200
  • UC San Diego Health24
  • Rady Children's Hospital24
  • MPF Federal12
  • Lorian Health12

Top Industries Hiring

  • Healthcare & Medical Services

Clinical Nurse Jobs in San Diego: Frequently Asked Questions

How do I get a clinical nurse job in San Diego?

The strongest path is targeting San Diego's large integrated health systems, which staff acute care, surgical, and specialty units across the city, along with the cluster of outpatient and ambulatory care centers in Mission Valley and Kearny Mesa. Candidates with experience in high-acuity settings, bilingual Spanish proficiency, or a specialty certification in critical care or emergency nursing stand out in this competitive coastal market.

Which companies hire clinical nurses in San Diego?

San Diego clinical nurse roles are posted by Sharp HealthCare, UC San Diego Health, and Rady Children's Hospital and others right now, based on current listings on Migrate Mate as of November 2026. The local market is driven by large academic medical centers, regional hospital networks, and a growing number of specialty and multispecialty outpatient groups serving San Diego's diverse population.

Are there remote clinical nurse jobs in San Diego?

Yes, though hands-on bedside and procedural roles are by nature on-site, making fully remote work uncommon for most clinical nurse positions. About 100% of clinical nurse openings tied to San Diego are remote or hybrid as of November 2026, with those opportunities most often found in utilization review, case management, and telehealth triage roles tied to San Diego-based health plans and managed care organizations.

How can I get a clinical nurse job in San Diego with little or no experience?

The most realistic entry path is applying to new graduate residency programs offered by San Diego's larger hospital systems, which are designed specifically for RNs completing their first year of practice. Community hospitals and federally qualified health centers serving neighborhoods like City Heights and National City also hire early-career nurses for medical-surgical and primary care roles. Completing a preceptorship or clinical rotation at a San Diego facility and obtaining Basic Life Support and ACLS certification before applying gives candidates a practical edge.

Which industries hire the most clinical nurses in San Diego?

San Diego clinical nurse roles concentrate in Healthcare & Medical Services, based on current listings on Migrate Mate as of November 2026. San Diego's large military and veterans health infrastructure, research-driven biotech sector, and network of community health centers all generate consistent clinical nurse demand alongside the city's major hospital systems.

See All 318+ Clinical Nurse Jobs in San Diego

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