Clinical Registered Nurse Jobs in Chicago, IL

Clinical Registered Nurse jobs in Chicago are concentrated across major academic medical centers and specialty hospital systems in the Medical District, Streeterville, and Hyde Park, with strong demand in critical care, oncology, and emergency settings. Employers actively hiring include Rush University Medical Center, SAINT MARY OF NAZARETH HOSPITAL, and Advocate Aurora Health. Find a role that fits below and apply directly.

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Overview

Open roles113+
Top employerRush University Medical Center
Work type64% On-site
Top credentialManaged Registered Nurses (RNs)
Companies hiring15

Showing 5 of 113+ Clinical Registered Nurse jobs

Clinical Nurse Supervisor RN - Labor and Delivery
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Added 6d ago
Clinical Nurse Supervisor RN - Labor and Delivery
SAINT MARY OF NAZARETH HOSPITAL
Chicago, Illinois
Healthcare Administration
Human Resources
Nursing
$36.75 - $55.7/hr
Managed Registered Nurses (RNs)

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Registered Nurse Clinical Lead Med Surg
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Added 1w ago
Registered Nurse Clinical Lead Med Surg
Ascension
Chicago, Illinois
Healthcare Administration
Nursing
Patient Services & Wellbeing
$45.3 - $63.95/hr
Managed Registered Nurses (RNs)
10,000+

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MedTech Vascular Access RN Clinical Educator– Per Diem - Chicago, IL & Dallas, TX
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Added 1w ago
MedTech Vascular Access RN Clinical Educator– Per Diem - Chicago, IL & Dallas, TX
IQVIA
Chicago, Illinois
Healthcare Administration
Nursing
Patient Services & Wellbeing
$36 - $38/hr
Associate's degree
10,000+

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Clinical Specialist Wound Care Supplies RN LPN
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Added 1w ago
Clinical Specialist Wound Care Supplies RN LPN
Asure Wound Solutions
Chicago, Illinois
Healthcare Administration
Nursing
Patient Services & Wellbeing
$75k - $85k/yr
Remote (US)
11-50

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Clinical Supervisor RN - Acute Psychiatric
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Added 1w ago
Clinical Supervisor RN - Acute Psychiatric
SAINT MARY OF NAZARETH HOSPITAL
Chicago, Illinois
Healthcare Administration
Human Resources
Nursing
$41 - $64.09/hr
Managed Registered Nurses (RNs)

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Clinical Registered Nurse Job Market in Chicago

Who's Hiring

  • Rush University Medical Center25
  • SAINT MARY OF NAZARETH HOSPITAL14
  • Advocate Aurora Health11
  • IQVIA7
  • Ascension7

Top Industries Hiring

  • Education
  • Healthcare & Medical Services
  • Transportation & Logistics

Clinical Registered Nurse Jobs in Chicago: Frequently Asked Questions

How do I get a clinical registered nurse job in Chicago?

The strongest path into Chicago's clinical registered nurse market runs through its large academic hospital systems, Level I trauma centers, and specialty care networks, which dominate hiring across the Medical District, Streeterville, and the Near North Side. Candidates with acute care experience, specialty certifications such as CCRN or OCN, and familiarity with Epic clinical systems have a clear edge. Applying directly to hospital system career portals and targeting units with known staffing pressure, like ICU, emergency, and oncology, moves applications forward fastest.

Which companies hire clinical registered nurses in Chicago?

Companies currently hiring clinical registered nurses in Chicago include Rush University Medical Center, SAINT MARY OF NAZARETH HOSPITAL, and Advocate Aurora Health, per current listings on Migrate Mate as of October 2026. Chicago's market is anchored by large integrated health systems and nationally ranked academic medical centers that hire across inpatient, outpatient, and specialty care settings year-round.

Are there remote clinical registered nurse jobs in Chicago?

Yes, but only for a narrow subset of roles, since most clinical registered nurse positions require direct patient contact and on-site presence. About 36% of clinical registered nurse openings tied to Chicago are remote or hybrid as of October 2026, concentrated in utilization review, case management, and telehealth triage functions. Chicago-based managed care organizations and insurance carriers are the primary employers offering those arrangements.

How can I get a clinical registered nurse job in Chicago with little or no experience?

The most realistic entry point in Chicago is a new graduate residency or nurse externship program offered by the city's large academic hospital systems, which are structured specifically to bring ADN and BSN graduates into acute care with supervised clinical progression. Community hospitals on Chicago's South and West Sides often have more accessible hiring pipelines for new grads than the flagship downtown campuses. Building experience in a med-surg or step-down unit first, then pursuing a specialty certification, is the standard trajectory local nurse managers recognize.

Which industries hire the most clinical registered nurses in Chicago?

Most clinical registered nurse openings in Chicago sit in Education, Healthcare & Medical Services, and Transportation & Logistics, per current listings on Migrate Mate as of October 2026. Chicago's density of nationally ranked academic medical centers, large integrated hospital systems, and a growing ambulatory and specialty clinic network collectively sustain consistent demand across inpatient and outpatient settings.

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