Clinical Registered Nurse Jobs in Chicago, IL
Clinical Registered Nurse jobs in Chicago are concentrated across major academic medical centers and specialty hospital systems in the Medical District, Streeterville, and Hyde Park, with strong demand in critical care, oncology, and emergency settings. Employers actively hiring include Northwestern Medicine, Rush University Medical Center, and SAINT MARY OF NAZARETH HOSPITAL. Find a role that fits below and apply directly.
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Major Responsibilities:
- Provides work direction to the clinical and support staff with responsibility for the coordination of resources to efficiently support procedures, day-to-day operations and the smooth flow of patients through the department.
- Provides support for direct patient care by performing the nursing process to deliver safe, therapeutic, and quality care through assessment of patients, establishment and implementation of the nursing care plan, and evaluation of clinical outcomes when necessary. Promotes an environment conducive to the delivery of safe, efficient and quality patient care, which may include performing patient rounding on a daily basis.
- Coordinates the needs of the patient care team by initiating service complaint follow-up when necessary and promoting communication among patients, families, hospital departments and medical staff to optimize the interdependence of team members.
- Acts as a resource to employees, which includes training/orienting, providing day-to-day work direction, and giving input on performance. Assigns, monitors, and reviews progress and accuracy of work, directs efforts and provides guidance on more complex issues in collaboration with the unit leadership.
- Assists with human resource responsibilities, which may include: interviewing and selection of new employees, resolution of employee concerns, and employee moral or other duties as assigned in collaboration with unit leadership.
- Monitors employee assignments and works on assignments for the unit. Evaluates staffing levels and makes adjustments as necessary to maintain productivity level established for assigned area(s).
- Monitors the quality of care provided. Assists in ensuring policies and procedures are followed in compliance with the medical center, the Nursing department, and regulatory and peer review agencies.
- Provides input to budget and ensures adequate supplies and equipment and inventory are available for both the delivery of safe patient care and a safe work environment.
- Works with management in developing new and existing programs and services.
- Works with vendors for requested products and coordinates in-services for equipment. Participates in product trials, and submits recommendations to management in collaboration with the unit Educator or CNS.
- Must be able to demonstrate knowledge and skills necessary to provide care appropriate to the age of the patients served. Must demonstrate knowledge of the principles of growth and development over the life span and possess the ability to assess data reflective of the patient's status and interpret the appropriate information needed to identify each patient's requirements relative to his/her age-specific needs, and to provide the care needed as described in the department's policies and procedures. Age-specific information is developed further in the departmental job standards.
Licensure:
- Nurse, Registered (RN)
Education/Experience Required:
- Bachelor's Degree in Nursing or Health Related Field; or Associate Degree and enrolled in BSN program within 2 years of hire and complete BSN degree within 5 years. Typically requires 3 years of experience in clinical nursing within an acute care setting.
Knowledge, Skills & Abilities Required:
- Demonstrates a holistic approach to nursing practice committed to meeting the needs of the patient and family. Clinical and technical knowledge in area(s) of specialty. Ability to apply evidence-based interventions and nursing skills/technology to correlate to the patient’s response to an individualized plan of care. Ability to recognize situational changes that require unplanned interventions. Proficient computer skills including keyboarding, navigation within a windows operating system, use of electronic mail and electronic medical records systems. Excellent communication, listening and interpersonal skills. Demonstrates human relation skills with the ability to develop rapport and maintain positive, professional relationships with a variety of patients, staff and physicians. Demonstrated ability to effectively make critical, independent decisions and the ability to think ahead, anticipate learning needs and take preventive actions. Excellent organization, prioritization and problem solving skills. Demonstrates time management skills with an ability to multi-task and prioritize with frequent interruptions. Skilled at coaching and developing employees to achieve the quality and service standards of the unit and medical center.
- Registered Nurse license issued by the state in which the team member practices, and Basic Life Support (BLS) for Healthcare Providers certification issued by the American Heart Association (AHA) needs to be obtained within 6 months unless department leader has determined it is not required.
Certification Addendum:
- Team members will maintain annual educational requirements for hospital based certifications (e.g. DNV, CARF or others)
Physical Requirements and Working Conditions:
- Must be able to sit, stand, walk, lift, squat, bend, reach above shoulders, and twist frequently throughout the workday. Must be able to: lift up to 50 lbs. from floor to waist; lift up to 20 lbs. over the head; carry up to 40 lbs. a reasonable distance. Must be able to: push/pull with 30 lbs. of force; perform a sliding transfer of 150 lbs. with a second person present. Position requires use of foot pedals on carts or machines. May be exposed to chemical and hazardous waste as well as blood and body fluids and communicable disease. Therefore, protective clothing and equipment must be worn as necessary. Must have functional speech, vision, hearing, and touch with ability to use fine hand manipulation skills for IV insertion and other procedures/functions. Operates all equipment necessary to perform the job. This job description indicates the general nature and level of work expected of the incumbent. It is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities required of the incumbent. Incumbent may be required to perform other related duties.
This job description indicates the general nature and level of work expected of the incumbent. It is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities required of the incumbent. Incumbent may be required to perform other related duties.
See All 81 Clinical Registered Nurse Jobs in Chicago
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Find JobsClinical Registered Nurse Job Market in Chicago
Who's Hiring
- Northwestern Medicine16

- Rush University Medical Center16

- SAINT MARY OF NAZARETH HOSPITAL11S
- Advocate Aurora Health9

- Endeavor Health3

Top Industries Hiring
- Healthcare & Medical Services54
- Education10
- Consulting & Professional Services2
- Science & Research1
- Transportation & Logistics1
Clinical Registered Nurse Jobs in Chicago: Frequently Asked Questions
How do I get a clinical registered nurse job in Chicago?
The strongest path into Chicago's clinical registered nurse market runs through its large academic hospital systems, Level I trauma centers, and specialty care networks, which dominate hiring across the Medical District, Streeterville, and the Near North Side. Candidates with acute care experience, specialty certifications such as CCRN or OCN, and familiarity with Epic clinical systems have a clear edge. Applying directly to hospital system career portals and targeting units with known staffing pressure, like ICU, emergency, and oncology, moves applications forward fastest.
Which companies hire clinical registered nurses in Chicago?
Companies currently hiring clinical registered nurses in Chicago include Northwestern Medicine, Rush University Medical Center, and SAINT MARY OF NAZARETH HOSPITAL, per current listings on Migrate Mate as of June 2026. Chicago's market is anchored by large integrated health systems and nationally ranked academic medical centers that hire across inpatient, outpatient, and specialty care settings year-round.
Are there remote clinical registered nurse jobs in Chicago?
Yes, but only for a narrow subset of roles, since most clinical registered nurse positions require direct patient contact and on-site presence. About 2% of clinical registered nurse openings tied to Chicago are remote or hybrid as of June 2026, concentrated in utilization review, case management, and telehealth triage functions. Chicago-based managed care organizations and insurance carriers are the primary employers offering those arrangements.
How can I get a clinical registered nurse job in Chicago with little or no experience?
The most realistic entry point in Chicago is a new graduate residency or nurse externship program offered by the city's large academic hospital systems, which are structured specifically to bring ADN and BSN graduates into acute care with supervised clinical progression. Community hospitals on Chicago's South and West Sides often have more accessible hiring pipelines for new grads than the flagship downtown campuses. Building experience in a med-surg or step-down unit first, then pursuing a specialty certification, is the standard trajectory local nurse managers recognize.
Which industries hire the most clinical registered nurses in Chicago?
Most clinical registered nurse openings in Chicago sit in Healthcare & Medical Services, Education, and Consulting & Professional Services, per current listings on Migrate Mate as of June 2026. Chicago's density of nationally ranked academic medical centers, large integrated hospital systems, and a growing ambulatory and specialty clinic network collectively sustain consistent demand across inpatient and outpatient settings.
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