Clinical Registered Nurse Jobs in Chicago, IL
Clinical Registered Nurse jobs in Chicago are concentrated across major academic medical centers and specialty hospital systems in the Medical District, Streeterville, and Hyde Park, with strong demand in critical care, oncology, and emergency settings. Employers actively hiring include Rush University Medical Center, SAINT MARY OF NAZARETH HOSPITAL, and Sinai Chicago. Find a role that fits below and apply directly.
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Hourly Pay Range:
$36.00 - $55.80 - The hourly pay rate offered is determined by a candidate's expertise and years of experience, among other factors.Endeavor Health is currently conducting a comprehensive review of our compensation structure. The new minimum for this role will be adjusted to $37.25 base pay hourly rate beginning with the second paycheck in October.
Position Highlights:
The Clinical Decisional Unit is a low acuity unit that monitors and evaluates patients for an observation period of up to 16 hours. During the stay, a decision is made whether to discharge or admit the patient. If you enjoy a fast-paced, hospital-based patient care environment, this may be the unit for you!
- Sign On Bonus: None
- Position: Registered Nurse – Clinical Decisional Unit - Nights
- Location: Chicago, IL
- Full Time (36 hours/week)
- Hours: Nights (7p-730a); every other weekend and rotating holidays required
- Required Travel: May float to other inpatient units as needed.
What you will do:
- Utilizes the nursing process to assess, diagnosis, plan, implement and evaluate the delivery of nursing care to patients and their families.
- Maintains competency reflective of current standards practice.
- Interacts and contributes to the professional development of peers and colleagues.
- Integrates ethical provisions in all areas of nursing practice.
- Integrates evidence-based practice and research findings into nursing practice.
- Recognizes and adjusts to situations that vary from the norm.
- Promotes safety measures to prevent patient and staff injuries.
- Guides and supervises staff in the provision of patient care.
- Enhances own professional growth and development.
- Maintains a safe therapeutic working environment and recognizes need for action in emergency situations.
- Documentation is thoroughly and timely completed
- Performs other related duties as assigned or requested.
What you will need:
- At least one year of experience as a staff nurse preferred
- At least 1 year of Cardiac Tele Experience preferred
- Critical Care experience is preferred
- Graduate from an accredited school of nursing.
- Demonstrates mastery of nursing skills.
- Communicates effectively and is able to guide and supervise nursing personnel.
- Current Illinois Nursing licensure
- American Heart Association CPR Certification
- American Heart Association ACLS Certification required with in 3 months of hire
- NIHSS Certification within one month of hire
- PALS, NRP may be required within six months depending on the unit requirements
Benefits:
- Premium pay such as shift, on call, holiday and more based on an employee’s job (For eligible positions)
- Incentive pay for select positions
- Opportunity for annual increases based on performance
- Career Pathways to Promote Professional Growth and Development
- Various Medical, Dental, Pet and Vision options
- Tuition Reimbursement
- Discounted Parking
- Wellness Program Savings Plan
- Health Savings Account Options
- Retirement Options with Company Match
- Paid Time Off and Holiday Pay
- Community Involvement Opportunities
Endeavor Health is a fully integrated healthcare delivery system committed to providing access to quality, vibrant, community-connected care, serving an area of more than 4.2 million residents across six northeast Illinois counties. Our more than 25,000 team members and more than 6,000 physicians aim to deliver transformative patient experiences and expert care close to home across more than 300 ambulatory locations and eight acute care hospitals – Edward (Naperville), Elmhurst, Evanston, Glenbrook (Glenview), Highland Park, Northwest Community (Arlington Heights) Skokie and Swedish (Chicago) – all recognized as Magnet hospitals for nursing excellence. For more information, visit www.endeavorhealth.org.
When you work for Endeavor Health, you will be part of an organization that encourages its employees to achieve career goals and maximize their professional potential.
Please explore our website (www.endeavorhealth.org) to better understand how Endeavor Health delivers on its mission to “help everyone in our communities be their best”.
Endeavor Health is committed to working with and providing reasonable accommodation to individuals with disabilities. Please refer to the main career page for more information.
At Endeavor Health, we are united by a shared commitment to working together to create a culture of connection and belonging—each of us bringing different skills and experiences as we deliver safe, seamless, and personal care. Every person, every time. We are committed to fostering an environment where all team members can be their best, learn, and pursue excellence together.
EOE: Race/Color/Sex/Sexual Orientation/ Gender Identity/Religion/National Origin/Disability/Vets, VEVRRA Federal Contractor.
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Find JobsClinical Registered Nurse Job Market in Chicago
Who's Hiring
- Rush University Medical Center29

- SAINT MARY OF NAZARETH HOSPITAL18

- Sinai Chicago7

- Advocate Aurora Health7

- Gift of Hope Organ & Tissue Donor Network7

Top Industries Hiring
- Healthcare & Medical Services21
- Education11
- Transportation & Logistics4
Clinical Registered Nurse Jobs in Chicago: Frequently Asked Questions
How do I get a clinical registered nurse job in Chicago?
The strongest path into Chicago's clinical registered nurse market runs through its large academic hospital systems, Level I trauma centers, and specialty care networks, which dominate hiring across the Medical District, Streeterville, and the Near North Side. Candidates with acute care experience, specialty certifications such as CCRN or OCN, and familiarity with Epic clinical systems have a clear edge. Applying directly to hospital system career portals and targeting units with known staffing pressure, like ICU, emergency, and oncology, moves applications forward fastest.
Which companies hire clinical registered nurses in Chicago?
Companies currently hiring clinical registered nurses in Chicago include Rush University Medical Center, SAINT MARY OF NAZARETH HOSPITAL, and Sinai Chicago, per current listings on Migrate Mate as of August 2026. Chicago's market is anchored by large integrated health systems and nationally ranked academic medical centers that hire across inpatient, outpatient, and specialty care settings year-round.
Are there remote clinical registered nurse jobs in Chicago?
Yes, but only for a narrow subset of roles, since most clinical registered nurse positions require direct patient contact and on-site presence. About 18% of clinical registered nurse openings tied to Chicago are remote or hybrid as of August 2026, concentrated in utilization review, case management, and telehealth triage functions. Chicago-based managed care organizations and insurance carriers are the primary employers offering those arrangements.
How can I get a clinical registered nurse job in Chicago with little or no experience?
The most realistic entry point in Chicago is a new graduate residency or nurse externship program offered by the city's large academic hospital systems, which are structured specifically to bring ADN and BSN graduates into acute care with supervised clinical progression. Community hospitals on Chicago's South and West Sides often have more accessible hiring pipelines for new grads than the flagship downtown campuses. Building experience in a med-surg or step-down unit first, then pursuing a specialty certification, is the standard trajectory local nurse managers recognize.
Which industries hire the most clinical registered nurses in Chicago?
Most clinical registered nurse openings in Chicago sit in Healthcare & Medical Services, Education, and Transportation & Logistics, per current listings on Migrate Mate as of August 2026. Chicago's density of nationally ranked academic medical centers, large integrated hospital systems, and a growing ambulatory and specialty clinic network collectively sustain consistent demand across inpatient and outpatient settings.
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