Clinical Registered Nurse Jobs in Illinois

Clinical Registered Nurse jobs in Illinois are among the most actively posted healthcare roles in the state, concentrated in hospital systems, ambulatory care centers, and specialty clinics, with openings for new graduates through senior charge nurses. The largest hiring markets are Chicago, Rockford, and Springfield, where major systems like Northwestern Medicine, Advocate Health Care, and OSF HealthCare consistently bring on clinical nurses. The highest-demand specialties in Illinois right now include critical care, med-surg, and perioperative nursing. Find a role that fits below and apply directly.

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Overview

Open roles111+
Top employerNorthwestern Medicine
Top cityChicago, IL
Cities hiring47
Work type63% On-site
Top industryHealthcare

Showing 5 of 111+ Clinical Registered Nurse jobs

Northwestern Medicine
Clinical Practice Specialist Registered Nurse Educator ICU Full-time Days
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Northwestern Medicine
New 14h ago
Clinical Practice Specialist Registered Nurse Educator ICU Full-time Days
Northwestern Medicine
DeKalb, Illinois
Business Operations
Project Management
Quality Assurance & Testing (QA Testing)
$40.5 - $64.8/hr
Bachelor of Science
10,000+

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Advocate Aurora Health
RN Clinical Lead - Outpatient Oncology 1.0 days
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Advocate Aurora Health
Added 1d ago
RN Clinical Lead - Outpatient Oncology 1.0 days
Advocate Aurora Health
Oak Lawn, Illinois
Communications
Content & Communications
Public Relations (PR)
$41.1 - $61.65/hr
Managed Registered Nurses (RNs)
10,000+

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Endeavor Health
RN - Clinical Decisional Unit - Nights
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Endeavor Health
Added 1d ago
RN - Clinical Decisional Unit - Nights
Endeavor Health
Chicago, Illinois
Clinical Trials
Healthcare Administration
Nursing
Patient Services & Wellbeing
$36 - $55.8/hr
Managed Registered Nurses (RNs)
10,000+

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Resurrection Medical Center
Clinical Supervisor RN- Medical Surgical - Oncology
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Resurrection Medical Center
Added 1d ago
Clinical Supervisor RN- Medical Surgical - Oncology
Resurrection Medical Center
Chicago, Illinois
Corporate Training
Learning & Development
Project Management
$36.75 - $55.7/hr
Managed Registered Nurses (RNs)

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Carle Health
Clinical Transitions Spec RN - CMH IP Clin Case Mgmt
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Carle Health
Added 2d ago
Clinical Transitions Spec RN - CMH IP Clin Case Mgmt
Carle Health
Peoria, Illinois
Customer Service
Healthcare Administration
Human Resources
$35 - $58/hr
Bachelor's degree
10,000+

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See All 111+ Clinical Registered Nurse Jobs in Illinois

Find roles in Illinois that match your experience and apply in just a few clicks.

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Clinical Registered Nurse Jobs by City in Illinois

Where Illinois roles are concentrated, by current openings.

Lombard
6 jobs
Winfield
6 jobs
Peoria
5 jobs
Oak Lawn
5 jobs
Aurora
4 jobs
Macomb
2 jobs
Skokie
2 jobs
Urbana
2 jobs

Clinical Registered Nurse Job Market in Illinois

A snapshot from current Illinois openings, updated as new roles post.

Who's Hiring

  • Northwestern Medicine
    Northwestern Medicine14
  • Advocate Aurora Health
    Advocate Aurora Health12
  • Rush University Medical Center
    Rush University Medical Center8
  • Carle Health
    Carle Health7
  • Fresenius Medical Care
    Fresenius Medical Care5

Top Industries Hiring

  • Healthcare & Medical Services21
  • Education3
  • Transportation & Logistics1

What Illinois Employers Look For

The qualifications that appear most often in clinical registered nurse jobs across Illinois.

  • Active registered nurse license issued or recognized by the Illinois Department of Financial and Professional Regulation
  • Associate or Bachelor of Science in Nursing degree from an accredited nursing program
  • Current BLS certification required before starting clinical patient care
  • Minimum one year of acute care or clinical nursing experience in a relevant setting
  • Strong working knowledge of electronic health record systems such as Epic or Cerner
  • Ability to collaborate with interdisciplinary care teams in a fast-paced clinical environment

Clinical Registered Nurse Jobs in Illinois: Frequently Asked Questions

How do you become a clinical registered nurse in Illinois?

You become a clinical registered nurse in Illinois by completing an accredited Associate Degree in Nursing or Bachelor of Science in Nursing program, then passing the NCLEX-RN exam. Licensure is issued and renewed through the Illinois Department of Financial and Professional Regulation. Illinois also participates in the Nurse Licensure Compact, meaning nurses licensed in other compact states may practice in Illinois without obtaining a separate state license.

How much do clinical registered nurses make in Illinois?

Clinical registered nurses in Illinois earn a median of about $95,990 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $69,170 for the lowest 10% to over $118,190 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinical registered nurses in Illinois?

Employers hiring clinical registered nurses in Illinois right now include Northwestern Medicine, Advocate Aurora Health, and Rush University Medical Center, based on current listings on Migrate Mate as of August 2026. Illinois's dense concentration of Level I trauma centers, academic medical centers, and large regional health systems means consistent demand for clinical nursing staff across the state year-round.

Which Illinois cities have the most clinical registered nurse jobs?

The cities with the most clinical registered nurse openings in Illinois are Chicago, Lombard, and Winfield. Chicago drives the largest share of postings given its density of major academic medical centers and large hospital networks, while Rockford and Springfield generate steady demand through regional anchor systems like OSF HealthCare and HSHS serving their surrounding communities.

Are there remote clinical registered nurse jobs in Illinois?

Yes, but they're rare. Clinical registered nursing is fundamentally a hands-on, bedside role, so fully remote positions represent a small slice of the market. About 37% of clinical registered nurse openings tied to Illinois are remote or hybrid as of August 2026. The sub-roles most likely to allow remote work are telephonic triage nursing, utilization review, and care management positions that do not require direct patient contact.

How can I get hired as a clinical registered nurse in Illinois with little or no experience?

The most realistic entry path is applying directly to new-graduate residency programs, which large Illinois systems including Northwestern Medicine, Advocate Health Care, and University of Chicago Medicine run specifically for nurses with limited clinical hours. These structured programs provide supervised orientation across units such as med-surg and telemetry. Candidates who hold an active Illinois RN license and a BSN stand out, and those with CNA or patient care technician experience in Illinois facilities often move into RN roles with greater ease.

Where can I find and apply to clinical registered nurse jobs in Illinois?

You can find and apply to clinical registered nurse jobs in Illinois on Migrate Mate, which lists current Illinois openings across hospital systems, outpatient clinics, and specialty practices. Find roles that fit your experience and specialty and apply directly to the employers posting them.

See All 111+ Clinical Registered Nurse Jobs in Illinois

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