Clinical Registered Nurse Jobs in North Carolina
Clinical Registered Nurse jobs in North Carolina are consistently in demand, with active hiring across major health systems, academic medical centers, and outpatient networks serving patients from new graduate nurses through experienced senior clinicians. Charlotte, Raleigh-Durham, and Greensboro are the busiest hiring markets, anchored by employers such as Atrium Health, Duke Health, and UNC Health. The most sought-after specialties in North Carolina include critical care, emergency nursing, and med-surg, reflecting the state's large hospital footprint and growing population. Find a role that fits below and apply directly.
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Collects, stores and data enters all current and retroactive data regarding specialized patient populations for various disease specific specialty databases, registries and research projects. Assists any or all of the following with patient follow-up, studies and projects: physicians, surgeons, clinical specialty program coordinator, product-line/department managers and quality coordinators.
Major Responsibilities:
- Completes the process for timely submission of data at appropriate intervals to the various disease specific specialty databases (i.e. STS, ACC, AHA ) and other registries as required for compliance with membership and professional standards. Coordinates training sessions to assure that individuals with access to databases can perform data entry and/or reporting functions accurately with respect to data definitions, security and confidentiality.
- Performs inter-rater reliability and other data quality measures to assure that the Medical Center's data meets the various database, registry and internal data quality standards.
- Participates in performance improvement activities by identifying appropriate data sources for studies, performing data base queries and transferring pertinent data sets to authorized individuals for statistical analysis.
- Collaborates with Information Services to facilitate the implementation and on-going technical maintenance of the information systems.
- Prepares and presents specified site data on a routine basis to Administration, site based Quality Council and specialty section and other clinical specialty teams as requested.
- Prepares individual clinical specialty data requests within specified timeline.
- Establishes and maintains effective working relationships with the Quality Management Team to improve patient outcomes including active participation on workgroups. Assists with clinical specialty module including training, data conversion and education with IS.
- Performs data collection relating to clinical specialty patients using appropriate data collection forms and computer software. Obtains and evaluates data from outpatient clinics, physician offices, and health care facilities for data collection for reporting. Maintains accurate data base records of clinical specialty patients as defined by nationally recognized societies.
- Maintains effective case finding techniques to assure that all appropriate clinical specialty cases are included in the database. Extrapolates, reviews, and extracts pertinent clinical data. Supports research with data collection and other activities as protocols necessitate.
- Establishes and maintains effective working relationships with surgeons, physicians, Data Coordinators and team members to facilitate accurate data collection for reporting.
Licensure, Registration, and/or Certification Required:
- Registered Nurse license issued by the state in which the team member practices.
Education Required:
- Bachelor's Degree (or equivalent knowledge) in Nursing.
Experience Required:
- Typically requires 5 years of experience in the area in which data coordination will be performed.
Knowledge, Skills & Abilities Required:
- Knowledgeable and proficient in the use of software, data quality and database management.
- Understanding of basic statistical methods.
- Able to communicate and work well with surgeons, physicians, and other medical/nursing/ technical personnel.
- Must be able to work independently with a high degree of accuracy and attention to detail.
Physical Requirements and Working Conditions:
- Must be able to spend approximately 50% in sedentary work.
- Exposed to a clinical-environment (including operating room and diagnostic or interventional lab) and a normal office environment.
- May be exposed to radiation and human blood and body fluids on an infrequent basis and must therefore wear protective apparel as needed.
- Operates all equipment necessary to perform the job.
This job description indicates the general nature and level of work expected of the incumbent. It is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities required of the incumbent. Incumbent may be required to perform other related duties.
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Find JobsClinical Registered Nurse Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Clinical Registered Nurse Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
- UNC Health173

- Advocate Aurora Health15

- HealthTrust Workforce Solutions15

- Atrium Health10

- Novant Health7

Top Industries Hiring
- Healthcare & Medical Services
What North Carolina Employers Look For
The qualifications that appear most often in clinical registered nurse jobs across North Carolina.
- Active registered nurse license issued or recognized by the North Carolina Board of Nursing
- Associate degree in nursing minimum, with bachelor of science in nursing preferred by most employers
- Current BLS certification required before patient care begins
- One or more years of clinical bedside experience in an acute care or ambulatory setting
- Familiarity with electronic health record systems such as Epic or Meditech
- Strong assessment and clinical documentation skills appropriate to assigned patient population
Clinical Registered Nurse Jobs in North Carolina: Frequently Asked Questions
How do you become a clinical registered nurse in North Carolina?
You become a clinical registered nurse in North Carolina by completing an accredited nursing program, then passing the NCLEX-RN exam and applying for licensure through the North Carolina Board of Nursing. Most employers accept either an associate degree in nursing or a bachelor of science in nursing to sit for the exam. Once your license is active and in good standing with the Board, you are eligible to apply for clinical registered nurse positions across the state.
How much do clinical registered nurses make in North Carolina?
Clinical registered nurses in North Carolina earn a median of about $84,350 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $67,660 for the lowest 10% to over $110,220 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire clinical registered nurses in North Carolina?
Employers hiring clinical registered nurses in North Carolina right now include UNC Health, Advocate Aurora Health, and HealthTrust Workforce Solutions, based on current listings on Migrate Mate as of August 2026. North Carolina's large integrated health systems, particularly those tied to academic medical centers in the Research Triangle and Charlotte metro, tend to post the highest volume of clinical nursing openings on a rolling basis.
Which North Carolina cities have the most clinical registered nurse jobs?
Chapel Hill, Raleigh, and Charlotte have the most clinical registered nurse openings in North Carolina. Charlotte leads because of Atrium Health's large hospital network, while Raleigh-Durham draws volume from Duke Health and UNC Health along with a dense cluster of specialty and outpatient clinics tied to Research Triangle Park, and Greensboro contributes steady openings through Cone Health and the broader Triad region's growing patient population.
Are there remote clinical registered nurse jobs in North Carolina?
Yes, but they're rare. Clinical registered nursing is fundamentally a hands-on, patient-facing role, which limits remote options significantly. About 5% of clinical registered nurse openings tied to North Carolina are remote or hybrid as of August 2026, and those positions tend to concentrate in telephone triage, case management, and utilization review functions rather than direct bedside care.
How can I get hired as a clinical registered nurse in North Carolina with little or no experience?
The most realistic entry path is a new graduate nurse residency program, which major North Carolina employers such as Duke Health, UNC Health, and Atrium Health run specifically to support nurses with limited clinical hours. These structured programs pair new licensees with experienced mentors across high-volume units like med-surg and telemetry. Candidates who complete a North Carolina Board of Nursing-approved clinical practicum and hold a current BLS certification are in the strongest position when applications open, typically several months before graduation.
Where can I find and apply to clinical registered nurse jobs in North Carolina?
You can find and apply to clinical registered nurse jobs in North Carolina on Migrate Mate, which lists current openings from employers hiring across the state. Search the listings for roles that match your specialty, experience level, and preferred location, then apply directly to the ones that fit.
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