Clinical Registered Nurse Jobs in North Carolina

Clinical Registered Nurse jobs in North Carolina are consistently in demand, with active hiring across major health systems, academic medical centers, and outpatient networks serving patients from new graduate nurses through experienced senior clinicians. Charlotte, Raleigh-Durham, and Greensboro are the busiest hiring markets, anchored by employers such as Atrium Health, Duke Health, and UNC Health. The most sought-after specialties in North Carolina include critical care, emergency nursing, and med-surg, reflecting the state's large hospital footprint and growing population. Find a role that fits below and apply directly.

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Overview

Open roles269+
Top employerUNC Health
Top cityChapel Hill, NC
Cities hiring49
Work type95% On-site
Top industryHealthcare

Showing 5 of 269+ Clinical Registered Nurse jobs

Advocate Aurora Health
Data Analyst Senior Clinical Specialist, Registered Nurse
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Advocate Aurora Health
Added 1d ago
Data Analyst Senior Clinical Specialist, Registered Nurse
Advocate Aurora Health
Charlotte, North Carolina
Data Analytics
Data Science
$38.2 - $57.3/hr
Bachelor's degree
10,000+

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UNC Health
RN Clinical Nurse II Emergency Department
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UNC Health
Added 1d ago
RN Clinical Nurse II Emergency Department
UNC Health
Siler City, North Carolina
Business Development
Customer Success
Program Management
Project Management
$34.22 - $48.38/hr
On-Site
BLS Certification
10,000+

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UNC Health
RN Clinical Nurse II - 7CH Pediatric Surgery/Trauma
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UNC Health
Added 1d ago
RN Clinical Nurse II - 7CH Pediatric Surgery/Trauma
UNC Health
Chapel Hill, North Carolina
IT Support & Systems Administration
Program Management
Project & Program Management
Technical Product & Program Management
$34.22 - $48.38/hr
On-Site
BLS Certification
10,000+

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UNC Health
RN Clinical Nurse II - Med Observation Unit - Weekends
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UNC Health
Added 1d ago
RN Clinical Nurse II - Med Observation Unit - Weekends
UNC Health
Chapel Hill, North Carolina
Business Development
Customer Success
Program Management
Project Management
$34.22 - $48.38/hr
On-Site
BLS Certification
10,000+

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Fresenius Medical Care
Dialysis Clinical Manager Registered Nurse - RN
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Fresenius Medical Care
Added 1d ago
Dialysis Clinical Manager Registered Nurse - RN
Fresenius Medical Care
Knightdale, North Carolina
Cloud & DevOps
Data Analytics
IT Support
Managed Registered Nurses (RNs)
10,000+

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Clinical Registered Nurse Jobs by City in North Carolina

Where North Carolina roles are concentrated, by current openings.

Chapel Hill
86 jobs
Charlotte
21 jobs
Smithfield
15 jobs
Lenoir
7 jobs
Clyde
6 jobs
Clayton
6 jobs
Cary
5 jobs
Holly Springs
5 jobs

Clinical Registered Nurse Job Market in North Carolina

A snapshot from current North Carolina openings, updated as new roles post.

Who's Hiring

  • UNC Health
    UNC Health173
  • Advocate Aurora Health
    Advocate Aurora Health15
  • HealthTrust Workforce Solutions
    HealthTrust Workforce Solutions15
  • Atrium Health
    Atrium Health10
  • Novant Health
    Novant Health7

Top Industries Hiring

  • Healthcare & Medical Services

What North Carolina Employers Look For

The qualifications that appear most often in clinical registered nurse jobs across North Carolina.

  • Active registered nurse license issued or recognized by the North Carolina Board of Nursing
  • Associate degree in nursing minimum, with bachelor of science in nursing preferred by most employers
  • Current BLS certification required before patient care begins
  • One or more years of clinical bedside experience in an acute care or ambulatory setting
  • Familiarity with electronic health record systems such as Epic or Meditech
  • Strong assessment and clinical documentation skills appropriate to assigned patient population

Clinical Registered Nurse Jobs in North Carolina: Frequently Asked Questions

How do you become a clinical registered nurse in North Carolina?

You become a clinical registered nurse in North Carolina by completing an accredited nursing program, then passing the NCLEX-RN exam and applying for licensure through the North Carolina Board of Nursing. Most employers accept either an associate degree in nursing or a bachelor of science in nursing to sit for the exam. Once your license is active and in good standing with the Board, you are eligible to apply for clinical registered nurse positions across the state.

How much do clinical registered nurses make in North Carolina?

Clinical registered nurses in North Carolina earn a median of about $84,350 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $67,660 for the lowest 10% to over $110,220 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinical registered nurses in North Carolina?

Employers hiring clinical registered nurses in North Carolina right now include UNC Health, Advocate Aurora Health, and HealthTrust Workforce Solutions, based on current listings on Migrate Mate as of August 2026. North Carolina's large integrated health systems, particularly those tied to academic medical centers in the Research Triangle and Charlotte metro, tend to post the highest volume of clinical nursing openings on a rolling basis.

Which North Carolina cities have the most clinical registered nurse jobs?

Chapel Hill, Raleigh, and Charlotte have the most clinical registered nurse openings in North Carolina. Charlotte leads because of Atrium Health's large hospital network, while Raleigh-Durham draws volume from Duke Health and UNC Health along with a dense cluster of specialty and outpatient clinics tied to Research Triangle Park, and Greensboro contributes steady openings through Cone Health and the broader Triad region's growing patient population.

Are there remote clinical registered nurse jobs in North Carolina?

Yes, but they're rare. Clinical registered nursing is fundamentally a hands-on, patient-facing role, which limits remote options significantly. About 5% of clinical registered nurse openings tied to North Carolina are remote or hybrid as of August 2026, and those positions tend to concentrate in telephone triage, case management, and utilization review functions rather than direct bedside care.

How can I get hired as a clinical registered nurse in North Carolina with little or no experience?

The most realistic entry path is a new graduate nurse residency program, which major North Carolina employers such as Duke Health, UNC Health, and Atrium Health run specifically to support nurses with limited clinical hours. These structured programs pair new licensees with experienced mentors across high-volume units like med-surg and telemetry. Candidates who complete a North Carolina Board of Nursing-approved clinical practicum and hold a current BLS certification are in the strongest position when applications open, typically several months before graduation.

Where can I find and apply to clinical registered nurse jobs in North Carolina?

You can find and apply to clinical registered nurse jobs in North Carolina on Migrate Mate, which lists current openings from employers hiring across the state. Search the listings for roles that match your specialty, experience level, and preferred location, then apply directly to the ones that fit.

See All 269+ Clinical Registered Nurse Jobs in North Carolina

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