Medical Director Jobs in North Carolina
Medical Director jobs in North Carolina are in strong demand, concentrated in health system leadership, managed care, behavioral health, and public health organizations, with openings at every level from first-time clinical directors to senior executive roles overseeing regional operations. The heaviest hiring is in Charlotte, Raleigh-Durham, and Greensboro, where large employers like Atrium Health, UNC Health, and Novant Health maintain substantial operations. The most consistently sought specialties include population health management, utilization review, and behavioral health leadership. Find a role that fits below and apply directly.
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Showing 5 of 91+ Medical Director jobs
Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.
Purpose:
Provides medical oversight of clinical trials to ensure company SOPs, client directives, good clinical practice, and regulatory requirements are followed. Attends and presents at investigator and sponsor meetings, provides medical consultation to clients, investigators and project team members and supports business development activities.
We have successfully supported the top 50 pharmaceutical companies and more than 750 biotechs, spanning 2,700 clinical trials across 100+ countries in the last 5 years.
General Support:
- Ensure tasks delegated to PV are properly executed. Adhere to applicable regulations and ICH guidelines regarding clinical trials, regulatory documents, and safety issues. Follow client SOPs/directives and project-specific WPDs for assigned projects. Comply with CRG’s corporate policies and SOPs/WPDs.
- Provide medical consultation to team members and answer all study-related medical questions. Communicate clearly with associates and clients, maintaining an open line of communication to ensure all procedures are followed appropriately.
- Provide therapeutic training and protocol training on assigned studies, as requested.
- Assist in writing (interpretation of safety and efficacy data) and/or reviewing CSR, IND/NDA reports, ICSR, signal detection reports, periodic reports, RMP, REMS, CTD modules, etc., to ensure that the medical content is accurate and complete.
Clinical Trial Support:
- Monitor all safety variables (AE, laboratory abnormalities, changes in patient medical status, evaluation of prescribed concomitant medication for protocol restrictions, and un-blinding requests) of clinical studies.
- Discuss all medical concerns with principal investigators and clients (e.g., interpretation of inclusion/exclusion criteria) raised during the course of a study, using proper medical judgment in interpretation and decision-making regarding clinical situations as they relate to the investigational study.
- Provide medical review of adverse events of special interest, serious adverse events, and clinical outcomes events reported by study sites.
- Perform data review as specified in the client contract and data validation manual, including review of coding listings and/or full safety data to assess potential safety concerns.
Marketed Products Support:
- Manage signal detection activities, scientifically review aggregate reports, contribute to label updates, and support dossier maintenance and risk management activities.
- Medically review adverse event and serious adverse event data from all sources (solicited, spontaneous, literature, etc.) as contracted.
Education and Experience Requirements:
- MD or equivalent required. Active medical licensure preferred.
Candidates should have at least one of the following:
- Clinical experience in treating patients in the specialty or sub-specialty associated with the applicants training (comparable to 2 years).
- Suitable clinical trial experience in a Contract Research Organization, pharmaceutical company or as a principal investigator (comparable to 1-2 years) in the industry.
- Direct experience in safety/Pharmacovigilance (comparable to 2 years).
For Senior Medical Director:
- MD or equivalent required. Active medical licensure preferred.
Candidates should have a combination of clinical experience and industry experience as follows:
- Clinical experience in treating patients in the specialty or sub-specialty associated with the applicants training (comparable to 2 years) and one of the following:
- Suitable clinical trial experience in a Contract Research Organization, pharmaceutical company or as a principal investigator (comparable to 1-2 years) in the industry; Or
- Direct experience in safety/Pharmacovigilance (comparable to 2 years)
In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
Knowledge, Skills, Abilities:
- Therapeutic expertise across one or more medical specialty or sub-specialties
- Strong decision-making, problem solving, organizational skills and analytical skills
- Excellent oral and written communication skills
- Working knowledge of relevant safety databases (e.g. Medra)
- Flexibility to travel domestically and internationally
- Ability to work independently, analyze work with attention to detail, process and prioritize sensitive
- Proficiency in basic computer applications
- Fluent in spoken and written English
- Excellent interpersonal, influencing and team building skills
- Understanding guidelines (FDA, ICH, EMA and GCP)
- Working knowledge of biostatistics, data management, and clinical operations procedures
- Ability to act as a mentor/trainer to other staff within PV
Working Environment:
Thermo Fisher Scientific values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive.
- Work is performed in an office environment with exposure to electrical office equipment.
- Occasional drives to site locations with occasional travel both domestic and international.
Work Schedule
Standard (Mon-Fri)Environmental Conditions
OfficeJob Description
At Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through research, development and delivery of life-changing therapies. With clinical trials conducted in 100+ countries and ongoing development of novel frameworks for clinical research through our PPD clinical research portfolio, our work spans laboratory, digital and decentralized clinical trial services. Your determination to deliver quality and accuracy will improve health outcomes that people and communities depend on – now and in the future.
Purpose:
Provides medical oversight of clinical trials to ensure company SOPs, client directives, good clinical practice, and regulatory requirements are followed. Attends and presents at investigator and sponsor meetings, provides medical consultation to clients, investigators and project team members and supports business development activities.
We have successfully supported the top 50 pharmaceutical companies and more than 750 biotechs, spanning 2,700 clinical trials across 100+ countries in the last 5 years.
General Support:
- Ensure tasks delegated to PV are properly executed. Adhere to applicable regulations and ICH guidelines regarding clinical trials, regulatory documents, and safety issues. Follow client SOPs/directives and project-specific WPDs for assigned projects. Comply with CRG’s corporate policies and SOPs/WPDs.
- Provide medical consultation to team members and answer all study-related medical questions. Communicate clearly with associates and clients, maintaining an open line of communication to ensure all procedures are followed appropriately.
- Provide therapeutic training and protocol training on assigned studies, as requested.
- Assist in writing (interpretation of safety and efficacy data) and/or reviewing CSR, IND/NDA reports, ICSR, signal detection reports, periodic reports, RMP, REMS, CTD modules, etc., to ensure that the medical content is accurate and complete.
Clinical Trial Support:
- Monitor all safety variables (AE, laboratory abnormalities, changes in patient medical status, evaluation of prescribed concomitant medication for protocol restrictions, and un-blinding requests) of clinical studies.
- Discuss all medical concerns with principal investigators and clients (e.g., interpretation of inclusion/exclusion criteria) raised during the course of a study, using proper medical judgment in interpretation and decision-making regarding clinical situations as they relate to the investigational study.
- Provide medical review of adverse events of special interest, serious adverse events, and clinical outcomes events reported by study sites.
- Perform data review as specified in the client contract and data validation manual, including review of coding listings and/or full safety data to assess potential safety concerns.
Marketed Products Support:
- Manage signal detection activities, scientifically review aggregate reports, contribute to label updates, and support dossier maintenance and risk management activities.
- Medically review adverse event and serious adverse event data from all sources (solicited, spontaneous, literature, etc.) as contracted.
Education and Experience Requirements:
- MD or equivalent required. Active medical licensure preferred.
Candidates should have at least one of the following:
- Clinical experience in treating patients in the specialty or sub-specialty associated with the applicants training (comparable to 2 years).
- Suitable clinical trial experience in a Contract Research Organization, pharmaceutical company or as a principal investigator (comparable to 1-2 years) in the industry.
- Direct experience in safety/Pharmacovigilance (comparable to 2 years).
For Senior Medical Director:
- MD or equivalent required. Active medical licensure preferred.
Candidates should have a combination of clinical experience and industry experience as follows:
- Clinical experience in treating patients in the specialty or sub-specialty associated with the applicants training (comparable to 2 years) and one of the following:
- Suitable clinical trial experience in a Contract Research Organization, pharmaceutical company or as a principal investigator (comparable to 1-2 years) in the industry; Or
- Direct experience in safety/Pharmacovigilance (comparable to 2 years)
In some cases an equivalency, consisting of a combination of appropriate education, training and/or directly related experience, will be considered sufficient for an individual to meet the requirements of the role.
Knowledge, Skills, Abilities:
- Therapeutic expertise across one or more medical specialty or sub-specialties
- Strong decision-making, problem solving, organizational skills and analytical skills
- Excellent oral and written communication skills
- Working knowledge of relevant safety databases (e.g. Medra)
- Flexibility to travel domestically and internationally
- Ability to work independently, analyze work with attention to detail, process and prioritize sensitive
- Proficiency in basic computer applications
- Fluent in spoken and written English
- Excellent interpersonal, influencing and team building skills
- Understanding guidelines (FDA, ICH, EMA and GCP)
- Working knowledge of biostatistics, data management, and clinical operations procedures
- Ability to act as a mentor/trainer to other staff within PV
Working Environment:
Thermo Fisher Scientific values the health and wellbeing of our employees. We support and encourage individuals to create a healthy and balanced environment where they can thrive.
- Work is performed in an office environment with exposure to electrical office equipment.
- Occasional drives to site locations with occasional travel both domestic and international.
See All 91 Medical Director Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find Medical Director JobsMedical Director Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Medical Director Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
- Animal Care & Pet Services
- Insurance
- Social Media
- Science & Research
What North Carolina Employers Look For
The qualifications that appear most often in medical director jobs across North Carolina.
- Active North Carolina medical license issued by the North Carolina Medical Board required
- MD or DO degree from an accredited medical school is required for all positions
- Board certification in a relevant specialty is required or strongly preferred by most employers
- Minimum of several years of clinical practice experience in addition to leadership responsibilities
- Demonstrated experience managing clinical teams, quality metrics, or utilization programs
- Familiarity with North Carolina regulatory environment, Medicaid policy, and compliance standards
Medical Director Jobs in North Carolina: Frequently Asked Questions
How do you become a medical director in North Carolina?
To become a medical director in North Carolina, you must hold an active medical license issued by the North Carolina Medical Board, which requires completing an accredited MD or DO program, passing the required medical licensing examinations, and maintaining ongoing continuing education. Most employers also expect board certification in a relevant specialty. From there, candidates typically move into medical director roles after gaining clinical experience and taking on leadership responsibilities such as department chair, associate medical director, or physician lead positions.
Which companies hire medical directors in North Carolina?
Employers hiring medical directors in North Carolina right now include Telos Health Systems, TeamHealth, and Novant Health, based on current listings on Migrate Mate as of August 2026. North Carolina's concentration of large integrated health systems, academic medical centers, and managed care organizations means medical director demand remains consistent across both clinical and administrative settings throughout the state.
Which North Carolina cities have the most medical director jobs?
Raleigh, Durham, and Charlotte have the most medical director openings in North Carolina. Charlotte and Raleigh-Durham lead because they are home to the state's largest health systems and academic medical centers, which generate sustained demand for both clinical and administrative medical director roles, while Greensboro and other Triad-area cities contribute openings tied to regional hospital networks and managed care organizations serving central North Carolina.
Are there remote medical director jobs in North Carolina?
Yes, but they are less common than in purely desk-based fields, since many medical director roles require on-site clinical oversight, rounding, or in-person leadership. About 65% of medical director openings tied to North Carolina are remote or hybrid as of August 2026. The roles most likely to be fully remote are those focused on utilization management, population health, insurance medical review, or telehealth program oversight rather than direct facility leadership.
How can I get hired as a medical director in North Carolina with little or no experience?
The most realistic entry path is moving laterally from a senior clinical or department lead role into an associate or assistant medical director position, which large North Carolina health systems like UNC Health and Atrium Health commonly post as stepping stones. Physicians in hospitalist, quality improvement, or care management roles are well positioned to make this transition. Completing a physician leadership development program, earning a healthcare management credential, or taking on a medical staff committee chair role strengthens a candidate's profile significantly.
Where can I find and apply to medical director jobs in North Carolina?
You can find and apply to medical director jobs in North Carolina on Migrate Mate, which lists current openings from employers hiring in the state right now. Search the available roles, find the ones that match your background and location, and apply directly to the positions that fit.
See All 91 Medical Director Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find Medical Director Jobs