Clinical Director Jobs in North Carolina
Clinical Director jobs in North Carolina are in strong demand, concentrated in healthcare systems, behavioral health networks, and outpatient specialty clinics, with openings ranging from newly promoted clinical leads through senior executive directors overseeing multi-site operations. The largest hiring metros are Charlotte, Raleigh, and Greensboro, where employers like Atrium Health, Duke University Health System, and Cone Health consistently recruit for these roles. Behavioral health, home health and hospice, and substance use treatment are among the most active specialties in the state right now. Find a role that fits below and apply directly.
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What you can expect
Location: 2301 Erwin Rd. Durham, NC 27705
This nursing leadership role is responsible for strategic, operational, financial, and quality oversight across a diverse portfolio of highly specialized pediatric and neonatal clinical services. The successful candidate will provide 24/7 leadership and accountability for assigned areas, partnering closely with physician, nursing, and administrative leaders to advance clinical excellence, patient safety, workforce engagement, patient experience, and operational performance. This role offers the opportunity to lead complex programs within a highly collaborative academic health system environment.
Schedule:
- Full Time: Monday - Friday, with off shift visibility and on call 24/7 including weekends.
Incentives & Total Rewards:
- Relocation Assistance: Up to $10,000 for eligible employees moving at least 50 miles from Duke University Hospital.
- Total Rewards: A comprehensive set of pay and benefits designed to support your well-being, professional growth, and work-life balance. Learn more here.
How you will make an impact
- Provide 24/7 leadership and accountability for strategic, operational, financial, and quality performance across assigned departments and a diverse portfolio of highly specialized pediatric and neonatal clinical services.
- Partner with physician, nursing, and administrative leaders to develop, execute, and continuously evaluate strategic and operational priorities.
- Foster a culture of excellence, innovation, safety, and continuous improvement that advances exceptional patient and family-centered care.
- Build, develop, and retain high-performing teams through effective recruitment, engagement, succession planning, and leadership development.
- Drive quality, safety, patient experience, workforce, and operational outcomes through the use of data, evidence-based practices, and performance improvement methodologies.
- Lead the development and refinement of care delivery models to support organizational goals and evolving patient care needs.
- Ensure effective stewardship of resources, including staffing, budgets, facilities, equipment, and operational systems.
- Champion shared governance and interdisciplinary collaboration while strengthening partnerships across the highly collaborative academic health system to achieve strategic objectives.
What you will need
- Bachelor or higher degree in Nursing and Master's Degree in related field.
- Five years of nursing experience is required, including at least 2 years of experience in a management role.
- Must have current or compact RN licensure in the state of North Carolina.
- BLS certification required.
- Ability to manage multiple organization missions.
- Facilitation, consensus-building, and negotiation skills.
- Sensitivity for and understanding of clinical disciplines and issues.
- Understanding of cost containment and managed care systems.
- Ability to work with all types of individuals in multiple settings and locations and to promote diversity in the workplace.
- Knowledge of necessary regulatory bodies, including the North Carolina Nurse Practice Act.
- Expert communication skills.
Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas — an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.
See All 66 Clinical Director Jobs in North Carolina
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Find Clinical Director JobsClinical Director Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Clinical Director Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Education
What North Carolina Employers Look For
The qualifications that appear most often in clinical director jobs across North Carolina.
- Active North Carolina license in a clinical discipline such as RN, LPC, or LCSW
- Master's degree in nursing, social work, counseling, or a related clinical field
- Minimum five years of direct clinical experience in a relevant care setting
- Prior supervisory or management experience overseeing clinical staff and programs
- Demonstrated knowledge of Joint Commission standards, state regulations, and accreditation requirements
- Strong background in quality improvement, outcomes tracking, and clinical program development
Clinical Director Jobs in North Carolina: Frequently Asked Questions
How do you become a clinical director in North Carolina?
Becoming a clinical director in North Carolina typically starts with earning an active clinical license in your discipline, such as a Registered Nurse license through the North Carolina Board of Nursing, a Licensed Clinical Social Worker credential through the NC Social Work Certification and Licensure Board, or a Licensed Professional Counselor designation through the NC Psychology Board. Employers generally require a master's degree and several years of progressive clinical and supervisory experience before hiring into a director-level role.
Which companies hire clinical directors in North Carolina?
Employers hiring clinical directors in North Carolina right now include Duke Health, Atrium Health, and Advocate Aurora Health, based on current listings on Migrate Mate as of October 2026. North Carolina's large integrated health systems and growing behavioral health networks tend to post the most consistent volume of these openings across the state.
Which North Carolina cities have the most clinical director jobs?
Charlotte, Durham, and Raleigh have the most clinical director openings in North Carolina. Charlotte and Raleigh drive the highest volume, anchored by major health systems like Atrium Health and WakeMed, while Greensboro's concentration of regional behavioral health and home health agencies accounts for strong demand in the Piedmont Triad.
Are there remote clinical director jobs in North Carolina?
Yes, but they're rare. Clinical director roles are primarily on-site positions that involve direct oversight of clinical staff, patient care environments, and facility operations. About 68% of clinical director openings tied to North Carolina are remote or hybrid as of October 2026, and those tend to be in utilization management, telehealth program leadership, or managed care settings where day-to-day duties don't require a physical presence.
How can I get hired as a clinical director in North Carolina with little or no experience?
The most realistic entry path is moving into a clinical supervisor or program manager role first, then building toward director-level positions. Large North Carolina health systems like Novant Health and Duke University Health System often hire clinical leads and charge nurses internally before elevating candidates to director roles. Earning a North Carolina clinical license in your discipline, completing a graduate degree, and gaining quality improvement or accreditation project experience are the credentials that most consistently open the door to director-track opportunities.
Where can I find and apply to clinical director jobs in North Carolina?
You can find and apply to clinical director jobs in North Carolina on Migrate Mate, which lists current North Carolina openings from employers across the state. Find roles that fit your background and apply directly to the ones that match.
See All 66 Clinical Director Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find Clinical Director Jobs