Primary Care Nurse Practitioner Jobs in North Carolina
Primary Care Nurse Practitioner jobs in North Carolina are in strong demand, concentrated across health systems, federally qualified health centers, and rural primary care practices, with openings at every level from new graduate to experienced lead clinician. The heaviest hiring activity is in Charlotte, Raleigh-Durham, and Greensboro, where major employers like UNC Health, Atrium Health, and Duke Health maintain large primary care networks. The most sought-after specialties in North Carolina include family medicine, adult-gerontology, and pediatric primary care. Find a role that fits below and apply directly.
Find JobsOverview
Showing 5 of 35+ Primary Care Nurse Practitioner jobs
Generation Clinical Partners (GCP) is seeking an experienced (minimum 2 years) Nurse Practitioner or Physician Assistant to join our medical practice.
The NP/PA serves as a critical member of the care team and will provide direct patient care, coordinate care transitions, and help lead quality improvement efforts in the senior living facility setting. The focus of this position is to provide comprehensive high quality, efficient, and responsive onsite care tailored to the unique needs of each resident.
1. We're physician led. We know what you need to do your best work.
2. We offer mentoring and collaboration from other staff NP/PAs and your physician, with the potential for leadership in our organization.
3. Work schedule flexibility and work life balance are top priorities.
4. Candidates need to be technology savvy. Our EHR is cloud based.
5. You will share in call rotation from home with your collaborating physician.
About Generation Clinical Partners
GCP providers work exclusively in skilled nursing facilities, nursing homes, and assisted living communities to improve clinical outcomes, reduce re‐admissions, and enhance the operational performance of the facility. Through our consistent presence and intensive focus on optimizing patient outcomes, our mission is to become the clinical partner of choice at the facilities in which we serve.
We offer the following benefits:
- Competitive base salary with annual and quarterly bonus based on productivity
- Company-paid comprehensive malpractice
- Traditional 401(k) plan with company match
- Group medical, dental and vision insurance
- Flexible Schedule
- 23 PTO days and up to 5 CME Days
- Profit sharing opportunities
Job Responsibilities
1. Within scope of practice, effectively manage acute and chronic conditions by developing and overseeing high quality, cost‐effective treatment plans for patients in the facility, including ordering and interpreting diagnostic tests and prescribing medications and other treatments as appropriate.
2. Provide patient/family education and counseling in the areas of self‐care, health promotion, maintenance, and disease prevention.
3. Work closely with collaborating physicians and other colleagues, which allows for consultation, collaboration, and/or referral.
4. Provide clinical leadership and education to nursing and other staff, including to facility performance improvement efforts.
5. Document all medical evaluations, diagnoses, procedures, treatment, outcomes, education, referrals and consultations according to established standards in GCP's provider‐friendly electronic health record.
6. Analyze new knowledge gained from conferences, workshops, professional literature, or hands‐on training and assimilates this knowledge into clinical practice.
7. Maintain strict confidentiality with regard to protected health information and understands and adheres to GCP's HIPAA Privacy and Security policy.
8. Share in taking calls with other GCP providers.
Qualifications and Skills
1. Current valid and unrestricted RN and NP/PA licensure in Missouri (and/or Illinois)
2. National Board Certification and MSN in related fields are strongly preferred.
3. 2+ years experience, preferably in acute‐care, post acute care, or inpatient rehabilitation practice settings.
4. Demonstrated interpersonal skills to be approachable and understandable to patients, families, and staff.
5. Ability to be flexible to meet the practice schedule so as to ensure appropriate coverage and high quality patient care.
6. Collaborative practice style and ability to work harmoniously with others.
7. Demonstrated skill in resolving conflicts and promoting positive outcomes for patients
Job Type: Full-time
Work Location: In person in Mecklenburg, NC
Salary: starts at $130,000/year
Generation Clinical Partners (GCP) is seeking an experienced (minimum 2 years) Nurse Practitioner or Physician Assistant to join our medical practice.
The NP/PA serves as a critical member of the care team and will provide direct patient care, coordinate care transitions, and help lead quality improvement efforts in the senior living facility setting. The focus of this position is to provide comprehensive high quality, efficient, and responsive onsite care tailored to the unique needs of each resident.
1. We're physician led. We know what you need to do your best work.
2. We offer mentoring and collaboration from other staff NP/PAs and your physician, with the potential for leadership in our organization.
3. Work schedule flexibility and work life balance are top priorities.
4. Candidates need to be technology savvy. Our EHR is cloud based.
5. You will share in call rotation from home with your collaborating physician.
About Generation Clinical Partners
GCP providers work exclusively in skilled nursing facilities, nursing homes, and assisted living communities to improve clinical outcomes, reduce re‐admissions, and enhance the operational performance of the facility. Through our consistent presence and intensive focus on optimizing patient outcomes, our mission is to become the clinical partner of choice at the facilities in which we serve.
We offer the following benefits:
- Competitive base salary with annual and quarterly bonus based on productivity
- Company-paid comprehensive malpractice
- Traditional 401(k) plan with company match
- Group medical, dental and vision insurance
- Flexible Schedule
- 23 PTO days and up to 5 CME Days
- Profit sharing opportunities
Job Responsibilities
1. Within scope of practice, effectively manage acute and chronic conditions by developing and overseeing high quality, cost‐effective treatment plans for patients in the facility, including ordering and interpreting diagnostic tests and prescribing medications and other treatments as appropriate.
2. Provide patient/family education and counseling in the areas of self‐care, health promotion, maintenance, and disease prevention.
3. Work closely with collaborating physicians and other colleagues, which allows for consultation, collaboration, and/or referral.
4. Provide clinical leadership and education to nursing and other staff, including to facility performance improvement efforts.
5. Document all medical evaluations, diagnoses, procedures, treatment, outcomes, education, referrals and consultations according to established standards in GCP's provider‐friendly electronic health record.
6. Analyze new knowledge gained from conferences, workshops, professional literature, or hands‐on training and assimilates this knowledge into clinical practice.
7. Maintain strict confidentiality with regard to protected health information and understands and adheres to GCP's HIPAA Privacy and Security policy.
8. Share in taking calls with other GCP providers.
Qualifications and Skills
1. Current valid and unrestricted RN and NP/PA licensure in Missouri (and/or Illinois)
2. National Board Certification and MSN in related fields are strongly preferred.
3. 2+ years experience, preferably in acute‐care, post acute care, or inpatient rehabilitation practice settings.
4. Demonstrated interpersonal skills to be approachable and understandable to patients, families, and staff.
5. Ability to be flexible to meet the practice schedule so as to ensure appropriate coverage and high quality patient care.
6. Collaborative practice style and ability to work harmoniously with others.
7. Demonstrated skill in resolving conflicts and promoting positive outcomes for patients
Job Type: Full-time
Work Location: In person in Mecklenburg, NC
Salary: starts at $130,000/year
See All 35 Primary Care Nurse Practitioner Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find JobsPrimary Care Nurse Practitioner Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Primary Care Nurse Practitioner Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
What North Carolina Employers Look For
The qualifications that appear most often in primary care nurse practitioner jobs across North Carolina.
- Active North Carolina NP license or license recognized through the Nurse Licensure Compact
- Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
- National board certification as a Family or Adult-Gerontology Nurse Practitioner
- DEA registration and prescriptive authority under a North Carolina collaborative practice agreement
- Experience conducting comprehensive physical exams and managing chronic disease panels
- Proficiency with electronic health record systems used in primary care settings
Primary Care Nurse Practitioner Jobs in North Carolina: Frequently Asked Questions
How do you become a primary care nurse practitioner in North Carolina?
You must hold a Master of Science in Nursing or Doctor of Nursing Practice with a primary care focus, pass a national certification exam through ANCC or AANP, and obtain licensure from the North Carolina Board of Nursing. North Carolina requires nurse practitioners to maintain a collaborative practice agreement with a supervising physician. You will also need DEA registration to prescribe controlled substances and must apply separately for prescriptive authority through the Board of Nursing.
How much do primary care nurse practitioners make in North Carolina?
Primary care nurse practitioners in North Carolina earn a median of about $128,990 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $103,530 for the lowest 10% to over $164,320 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire primary care nurse practitioners in North Carolina?
Employers hiring primary care nurse practitioners in North Carolina right now include WakeMed Health & Hospitals, UNC Health, and Novant Health, based on current listings on Migrate Mate as of October 2026. North Carolina's blend of large academic health systems, community health centers, and rural health networks means hiring activity is spread across both urban and underserved areas throughout the state.
Which North Carolina cities have the most primary care nurse practitioner jobs?
North Carolina, Durham, and Lenoir have the most primary care nurse practitioner openings in North Carolina. Charlotte and Raleigh-Durham generate the most volume because of their large academic medical centers and growing suburban populations, while smaller metros like Greensboro and Asheville see steady demand driven by regional hospital systems and federally qualified health centers serving surrounding rural communities.
Are there remote primary care nurse practitioner jobs in North Carolina?
Yes, but they're rare. Primary care nurse practitioner work is fundamentally hands-on and clinic-based, so fully remote positions are uncommon. About 18% of primary care nurse practitioner openings tied to North Carolina are remote or hybrid as of October 2026, and those roles typically involve telehealth-only practices or virtual urgent care platforms rather than traditional primary care panels.
How can I get hired as a primary care nurse practitioner in North Carolina with little or no experience?
The most realistic entry path is a new-graduate nurse practitioner residency or fellowship, and several North Carolina employers offer them, including UNC Health and Atrium Health, which run structured programs for new NPs entering primary care. Candidates transitioning from registered nurse roles in outpatient or chronic disease management often have an easier time landing first positions. Holding national board certification and a completed collaborative practice agreement before applying gives new graduates a measurable edge with North Carolina hiring managers.
Where can I find and apply to primary care nurse practitioner jobs in North Carolina?
You can find and apply to primary care nurse practitioner jobs in North Carolina on Migrate Mate, which lists current openings across the state. Search the listings for roles that match your specialty, experience level, and preferred location, then apply directly to the ones that fit.
See All 35 Primary Care Nurse Practitioner Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find Jobs