Primary Care Nurse Practitioner Jobs in North Carolina
Primary Care Nurse Practitioner jobs in North Carolina are in strong demand, concentrated across health systems, federally qualified health centers, and rural primary care practices, with openings at every level from new graduate to experienced lead clinician. The heaviest hiring activity is in Charlotte, Raleigh-Durham, and Greensboro, where major employers like UNC Health, Atrium Health, and Duke Health maintain large primary care networks. The most sought-after specialties in North Carolina include family medicine, adult-gerontology, and pediatric primary care. Find a role that fits below and apply directly.
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Showing 5 of 29+ Primary Care Nurse Practitioner jobs
About Us
One Medical is a primary care solution challenging the industry status quo by making quality care more affordable, accessible and enjoyable. But this isn't your average doctor's office. We're on a mission to transform healthcare, which means improving the experience for everyone involved - from patients and providers to employers and health networks. Our seamless in-office and 24/7 virtual care services, on-site labs, and programs for preventive care, chronic care management, common illnesses and mental health concerns have been delighting people for the past fifteen years.
In February 2023 we marked a milestone when One Medical joined Amazon. Together, we look to deliver exceptional health care to more consumers, employers, care team members, and health networks to achieve better health outcomes. As we continue to grow and seek to impact more lives, we're building a diverse, driven and empathetic team, while working hard to cultivate an environment where everyone can thrive.
Employment type:
- "Casual Employee" (per diem, hourly clinician role)
- 16-23 patient care hours per week
Location:
- Seeing patients across multiple offices in Durham, NC
- Weekly schedule will include hours at several clinics in North Carolina
What you'll be working on:
- Seeing patients with a broad array of patient needs; conducting a mix of acute, chronic, and well visits (not a panel-building role)
- Treating patients in-office as well as conducting occasional tele-health visits
- Ongoing collaboration with in-office teammates via daily huddles, as well as with virtual clinical teams
- Utilization of your specific clinical training and opportunities to perform in-office procedures
Education, licenses, and experiences required for this role:
- At least 2 years of primary care experience required.
- Currently licensed or ability to obtain licensure in the state of North Carolina
- The ability to build successful relationships with team members and communicate effectively both 1-on-1 and in groups.
- Can thrive in a fast-growing, mission driven organization focused on using data to improve patient outcomes.
- Board Certification.
One Medical providers also demonstrate:
- A passion for human-centered primary care
- The ability to successfully communicate with and provide care to individuals of all backgrounds
- The ability to effectively use technology to deliver high quality care
- Clinical proficiency in evidence-based primary care
- The desire to be an integral part of a team dedicated to changing healthcare delivery
- An openness to feedback and reflection to gain productive insight into strengths and weaknesses
- The ability to confidently navigate uncertain situations with both patients and colleagues
- Readiness to adapt personal and interpersonal behavior to meet the needs of our patients
Casual/Per Diem/Locums Providers receive
- Malpractice Insurance - Malpractice fees to insure your practice at One Medical is covered 100%
- UpToDate Subscription - An evidence-based clinical research tool
- One Medical Issued laptop (to allow for secure access to our EHR)
- Sick Time PTO eligible in accordance with local requirement
This is an hourly role based in Durham, NC
One Medical is committed to fair and equitable compensation practices.
The hourly rate for this role is $75.00 per hour. Final determination of starting pay may vary based on factors such as practice experience and patient care schedule. Additional pay may be determined for those candidates that exceed these specified qualifications and requirements. The total compensation package for this position may also include benefits. For more information, visit https://www.onemedical.com/careers/
One Medical offers a robust benefits package designed to aid your health and wellness. All regular team members working 24+ hours per week and their dependents are eligible for benefits starting on the team member's date of hire:
Taking care of you today
- Paid sabbatical for every five years of service
- Free One Medical memberships for yourself, your friends and family
- Employee Assistance Program - Free confidential services for team members who need help with stress, anxiety, financial planning, and legal issues
- Competitive Medical, Dental and Vision plans
- Pre-Tax commuter benefits
- PTO cash outs - Option to cash out up to 40 accrued hours per year
Protecting your future for you and your family
- 401K match
- Credit towards emergency childcare
- Company paid maternity and paternity leave
- Paid Life Insurance - One Medical pays 100% of the cost of Basic Life Insurance
- Disability insurance - One Medical pays 100% of the cost of Short Term and Long Term Disability Insurance
In addition to the comprehensive benefits package outlined above, practicing clinicians also receive
- Malpractice Insurance - Malpractice fees to insure your practice at One Medical is covered 100%.
- UpToDate Subscription - An evidence-based clinical research tool
- Continuing Medical Education (CME) - Receive an annual stipend for continuing medical education
- Rounds - Providers end patient care one hour early each week to participate in this shared learning experience
- Discounted rate to attend One Medical's Annual REAL primary care conference
One Medical is an equal opportunity employer, and we encourage qualified applicants of every background, ability, and life experience to contact us about appropriate employment opportunities.
One Medical participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S. Please refer to the E-Verification Poster and Right to Work Poster for additional information.
About Us
One Medical is a primary care solution challenging the industry status quo by making quality care more affordable, accessible and enjoyable. But this isn't your average doctor's office. We're on a mission to transform healthcare, which means improving the experience for everyone involved - from patients and providers to employers and health networks. Our seamless in-office and 24/7 virtual care services, on-site labs, and programs for preventive care, chronic care management, common illnesses and mental health concerns have been delighting people for the past fifteen years.
In February 2023 we marked a milestone when One Medical joined Amazon. Together, we look to deliver exceptional health care to more consumers, employers, care team members, and health networks to achieve better health outcomes. As we continue to grow and seek to impact more lives, we're building a diverse, driven and empathetic team, while working hard to cultivate an environment where everyone can thrive.
Employment type:
- "Casual Employee" (per diem, hourly clinician role)
- 16-23 patient care hours per week
Location:
- Seeing patients across multiple offices in Durham, NC
- Weekly schedule will include hours at several clinics in North Carolina
What you'll be working on:
- Seeing patients with a broad array of patient needs; conducting a mix of acute, chronic, and well visits (not a panel-building role)
- Treating patients in-office as well as conducting occasional tele-health visits
- Ongoing collaboration with in-office teammates via daily huddles, as well as with virtual clinical teams
- Utilization of your specific clinical training and opportunities to perform in-office procedures
Education, licenses, and experiences required for this role:
- At least 2 years of primary care experience required.
- Currently licensed or ability to obtain licensure in the state of North Carolina
- The ability to build successful relationships with team members and communicate effectively both 1-on-1 and in groups.
- Can thrive in a fast-growing, mission driven organization focused on using data to improve patient outcomes.
- Board Certification.
One Medical providers also demonstrate:
- A passion for human-centered primary care
- The ability to successfully communicate with and provide care to individuals of all backgrounds
- The ability to effectively use technology to deliver high quality care
- Clinical proficiency in evidence-based primary care
- The desire to be an integral part of a team dedicated to changing healthcare delivery
- An openness to feedback and reflection to gain productive insight into strengths and weaknesses
- The ability to confidently navigate uncertain situations with both patients and colleagues
- Readiness to adapt personal and interpersonal behavior to meet the needs of our patients
Casual/Per Diem/Locums Providers receive
- Malpractice Insurance - Malpractice fees to insure your practice at One Medical is covered 100%
- UpToDate Subscription - An evidence-based clinical research tool
- One Medical Issued laptop (to allow for secure access to our EHR)
- Sick Time PTO eligible in accordance with local requirement
This is an hourly role based in Durham, NC
One Medical is committed to fair and equitable compensation practices.
The hourly rate for this role is $75.00 per hour. Final determination of starting pay may vary based on factors such as practice experience and patient care schedule. Additional pay may be determined for those candidates that exceed these specified qualifications and requirements. The total compensation package for this position may also include benefits. For more information, visit https://www.onemedical.com/careers/
One Medical offers a robust benefits package designed to aid your health and wellness. All regular team members working 24+ hours per week and their dependents are eligible for benefits starting on the team member's date of hire:
Taking care of you today
- Paid sabbatical for every five years of service
- Free One Medical memberships for yourself, your friends and family
- Employee Assistance Program - Free confidential services for team members who need help with stress, anxiety, financial planning, and legal issues
- Competitive Medical, Dental and Vision plans
- Pre-Tax commuter benefits
- PTO cash outs - Option to cash out up to 40 accrued hours per year
Protecting your future for you and your family
- 401K match
- Credit towards emergency childcare
- Company paid maternity and paternity leave
- Paid Life Insurance - One Medical pays 100% of the cost of Basic Life Insurance
- Disability insurance - One Medical pays 100% of the cost of Short Term and Long Term Disability Insurance
In addition to the comprehensive benefits package outlined above, practicing clinicians also receive
- Malpractice Insurance - Malpractice fees to insure your practice at One Medical is covered 100%.
- UpToDate Subscription - An evidence-based clinical research tool
- Continuing Medical Education (CME) - Receive an annual stipend for continuing medical education
- Rounds - Providers end patient care one hour early each week to participate in this shared learning experience
- Discounted rate to attend One Medical's Annual REAL primary care conference
One Medical is an equal opportunity employer, and we encourage qualified applicants of every background, ability, and life experience to contact us about appropriate employment opportunities.
One Medical participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S. Please refer to the E-Verification Poster and Right to Work Poster for additional information.
See All 29 Primary Care Nurse Practitioner Jobs in North Carolina
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Find JobsPrimary Care Nurse Practitioner Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Primary Care Nurse Practitioner Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
- Technology & Software
What North Carolina Employers Look For
The qualifications that appear most often in primary care nurse practitioner jobs across North Carolina.
- Active North Carolina NP license or license recognized through the Nurse Licensure Compact
- Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
- National board certification as a Family or Adult-Gerontology Nurse Practitioner
- DEA registration and prescriptive authority under a North Carolina collaborative practice agreement
- Experience conducting comprehensive physical exams and managing chronic disease panels
- Proficiency with electronic health record systems used in primary care settings
Primary Care Nurse Practitioner Jobs in North Carolina: Frequently Asked Questions
How do you become a primary care nurse practitioner in North Carolina?
You must hold a Master of Science in Nursing or Doctor of Nursing Practice with a primary care focus, pass a national certification exam through ANCC or AANP, and obtain licensure from the North Carolina Board of Nursing. North Carolina requires nurse practitioners to maintain a collaborative practice agreement with a supervising physician. You will also need DEA registration to prescribe controlled substances and must apply separately for prescriptive authority through the Board of Nursing.
How much do primary care nurse practitioners make in North Carolina?
Primary care nurse practitioners in North Carolina earn a median of about $128,990 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $103,530 for the lowest 10% to over $164,320 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire primary care nurse practitioners in North Carolina?
Employers hiring primary care nurse practitioners in North Carolina right now include WakeMed Health & Hospitals, US Department of Veterans Affairs, and TeamHealth, based on current listings on Migrate Mate as of August 2026. North Carolina's blend of large academic health systems, community health centers, and rural health networks means hiring activity is spread across both urban and underserved areas throughout the state.
Which North Carolina cities have the most primary care nurse practitioner jobs?
Greensboro, Cary, and Durham have the most primary care nurse practitioner openings in North Carolina. Charlotte and Raleigh-Durham generate the most volume because of their large academic medical centers and growing suburban populations, while smaller metros like Greensboro and Asheville see steady demand driven by regional hospital systems and federally qualified health centers serving surrounding rural communities.
Are there remote primary care nurse practitioner jobs in North Carolina?
Yes, but they're rare. Primary care nurse practitioner work is fundamentally hands-on and clinic-based, so fully remote positions are uncommon. About 17% of primary care nurse practitioner openings tied to North Carolina are remote or hybrid as of August 2026, and those roles typically involve telehealth-only practices or virtual urgent care platforms rather than traditional primary care panels.
How can I get hired as a primary care nurse practitioner in North Carolina with little or no experience?
The most realistic entry path is a new-graduate nurse practitioner residency or fellowship, and several North Carolina employers offer them, including UNC Health and Atrium Health, which run structured programs for new NPs entering primary care. Candidates transitioning from registered nurse roles in outpatient or chronic disease management often have an easier time landing first positions. Holding national board certification and a completed collaborative practice agreement before applying gives new graduates a measurable edge with North Carolina hiring managers.
Where can I find and apply to primary care nurse practitioner jobs in North Carolina?
You can find and apply to primary care nurse practitioner jobs in North Carolina on Migrate Mate, which lists current openings across the state. Search the listings for roles that match your specialty, experience level, and preferred location, then apply directly to the ones that fit.
See All 29 Primary Care Nurse Practitioner Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
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