Clinical Director Jobs in Massachusetts
Clinical Director jobs in Massachusetts are in strong demand, with openings concentrated in healthcare systems, behavioral health networks, and academic medical centers at levels from program manager to senior executive clinical director. Boston, Worcester, and Springfield anchor most of the hiring, with major employers like Mass General Brigham, UMass Memorial Health, and Baystate Health maintaining consistent clinical director pipelines. The most in-demand specialties include behavioral health, home health and hospice, and rehabilitation services. Find a role that fits below and apply directly.
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Scholar Rock is seeking an experienced and motivated Senior Director, Head of Clinical Quality Assurance to provide strategic and operational leadership for Good Clinical Practice (GCP) quality across the company’s biologics clinical development portfolio. Reporting to the Head of Global Quality, this role will serve as the senior Clinical QA leader and trusted partner to Clinical Operations, Clinical Development, Regulatory Affairs, Pharmacovigilance, Biometrics, Data Management, and external clinical service providers. The position is accountable for clinical quality strategy, GCP quality systems, clinical quality risk management, CRO and vendor oversight, audit strategy, inspection readiness, quality metrics, and the maturation of fit-for-purpose processes that embed quality by design across the clinical trial lifecycle.
Position Responsibilities:
- Lead the Clinical Quality Assurance function, providing strategic direction and operational oversight for GCP quality across Scholar Rock-sponsored clinical trials, with a focus on biologics development programs.
- Serve as the senior GCP Quality partner to Clinical Operations, Clinical Development, Regulatory Affairs, Pharmacovigilance, Biometrics, Data Management, and other cross-functional stakeholders.
- Define, implement, and continuously mature the clinical quality strategy, governance model, and GCP quality management processes aligned with global regulatory expectations and clinical development priorities.
- Provide quality oversight for global clinical trials, including protocol compliance, informed consent processes, investigator site oversight, trial master file quality, data integrity, safety reporting interfaces, and clinical study documentation.
- Establish and execute a risk-based GCP audit program, including audits of investigator sites, CROs, vendors, clinical systems, TMF processes, and key internal clinical trial activities.
- Lead GCP inspection readiness activities and support preparation, conduct, response development, and follow-up for FDA, EMA, PMDA, and other health authority inspections.
- Provide oversight of GCP deviations, serious breaches, audit observations, inspection findings, CAPAs, and quality issues to ensure timely investigation, appropriate root cause analysis, effective corrective actions, and sustainable remediation.
- Oversee CRO and clinical vendor quality governance, including qualification, risk assessment, quality agreements where applicable, performance metrics, issue escalation, and continuous improvement.
- Partner with clinical and regulatory teams to proactively identify and mitigate quality risks associated with study design, trial execution, vendor performance, data integrity, patient safety, protocol deviations, and submission readiness.
- Develop and monitor GCP quality metrics, dashboards, and trend reports to support proactive risk management, governance discussions, and executive-level quality visibility.
- Author, review, and approve GCP-related SOPs, policies, quality plans, audit reports, CAPA plans, inspection materials, and other controlled documents as appropriate.
- Build, lead, and develop a fit-for-purpose Clinical QA function appropriate for a fast-paced, outsourced biotech operating model.
- Champion a culture of quality, accountability, patient safety, data integrity, transparency, and continuous improvement across internal teams and external partners.
Candidate Requirements:
- BS/MS degree in a scientific, healthcare, or related discipline; advanced degree preferred.
- 15+ years of experience in the pharmaceutical/biotech industry, including significant experience in Clinical Quality Assurance, Clinical Operations, clinical development, or related GCP compliance roles.
- 10+ years of hands-on GCP quality experience, including leadership of global clinical quality programs and oversight of Phase I–III clinical trials.
- Deep knowledge of ICH-GCP, ICH E6(R3), FDA, EMA, PMDA, and other global clinical trial regulations and expectations.
- Experience supporting biologics clinical development programs; late-stage development, registration-enabling studies, and inspection readiness experience strongly preferred.
- Demonstrated experience leading or supporting regulatory inspections, including inspection preparation, hosting, response development, CAPA management, and follow-up commitments.
- Strong experience with CRO and clinical vendor oversight, investigator site audits, TMF quality, clinical systems, data integrity, risk-based quality management, and quality issue escalation.
- Proven ability to design and mature fit-for-purpose GCP quality systems, SOPs, audit programs, quality metrics, governance forums, and inspection readiness frameworks in an outsourced biotech model.
- Strong judgment, executive presence, technical writing capability, and the ability to influence cross-functional leaders and external partners.
- Highly proactive, decisive, and capable of balancing strategic leadership with hands-on execution in a fast-paced environment.
- Engaged leader committed to building culture, mentoring talent, and developing scalable Clinical QA capabilities.
Scholar Rock is seeking an experienced and motivated Senior Director, Head of Clinical Quality Assurance to provide strategic and operational leadership for Good Clinical Practice (GCP) quality across the company’s biologics clinical development portfolio. Reporting to the Head of Global Quality, this role will serve as the senior Clinical QA leader and trusted partner to Clinical Operations, Clinical Development, Regulatory Affairs, Pharmacovigilance, Biometrics, Data Management, and external clinical service providers. The position is accountable for clinical quality strategy, GCP quality systems, clinical quality risk management, CRO and vendor oversight, audit strategy, inspection readiness, quality metrics, and the maturation of fit-for-purpose processes that embed quality by design across the clinical trial lifecycle.
Position Responsibilities:
- Lead the Clinical Quality Assurance function, providing strategic direction and operational oversight for GCP quality across Scholar Rock-sponsored clinical trials, with a focus on biologics development programs.
- Serve as the senior GCP Quality partner to Clinical Operations, Clinical Development, Regulatory Affairs, Pharmacovigilance, Biometrics, Data Management, and other cross-functional stakeholders.
- Define, implement, and continuously mature the clinical quality strategy, governance model, and GCP quality management processes aligned with global regulatory expectations and clinical development priorities.
- Provide quality oversight for global clinical trials, including protocol compliance, informed consent processes, investigator site oversight, trial master file quality, data integrity, safety reporting interfaces, and clinical study documentation.
- Establish and execute a risk-based GCP audit program, including audits of investigator sites, CROs, vendors, clinical systems, TMF processes, and key internal clinical trial activities.
- Lead GCP inspection readiness activities and support preparation, conduct, response development, and follow-up for FDA, EMA, PMDA, and other health authority inspections.
- Provide oversight of GCP deviations, serious breaches, audit observations, inspection findings, CAPAs, and quality issues to ensure timely investigation, appropriate root cause analysis, effective corrective actions, and sustainable remediation.
- Oversee CRO and clinical vendor quality governance, including qualification, risk assessment, quality agreements where applicable, performance metrics, issue escalation, and continuous improvement.
- Partner with clinical and regulatory teams to proactively identify and mitigate quality risks associated with study design, trial execution, vendor performance, data integrity, patient safety, protocol deviations, and submission readiness.
- Develop and monitor GCP quality metrics, dashboards, and trend reports to support proactive risk management, governance discussions, and executive-level quality visibility.
- Author, review, and approve GCP-related SOPs, policies, quality plans, audit reports, CAPA plans, inspection materials, and other controlled documents as appropriate.
- Build, lead, and develop a fit-for-purpose Clinical QA function appropriate for a fast-paced, outsourced biotech operating model.
- Champion a culture of quality, accountability, patient safety, data integrity, transparency, and continuous improvement across internal teams and external partners.
Candidate Requirements:
- BS/MS degree in a scientific, healthcare, or related discipline; advanced degree preferred.
- 15+ years of experience in the pharmaceutical/biotech industry, including significant experience in Clinical Quality Assurance, Clinical Operations, clinical development, or related GCP compliance roles.
- 10+ years of hands-on GCP quality experience, including leadership of global clinical quality programs and oversight of Phase I–III clinical trials.
- Deep knowledge of ICH-GCP, ICH E6(R3), FDA, EMA, PMDA, and other global clinical trial regulations and expectations.
- Experience supporting biologics clinical development programs; late-stage development, registration-enabling studies, and inspection readiness experience strongly preferred.
- Demonstrated experience leading or supporting regulatory inspections, including inspection preparation, hosting, response development, CAPA management, and follow-up commitments.
- Strong experience with CRO and clinical vendor oversight, investigator site audits, TMF quality, clinical systems, data integrity, risk-based quality management, and quality issue escalation.
- Proven ability to design and mature fit-for-purpose GCP quality systems, SOPs, audit programs, quality metrics, governance forums, and inspection readiness frameworks in an outsourced biotech model.
- Strong judgment, executive presence, technical writing capability, and the ability to influence cross-functional leaders and external partners.
- Highly proactive, decisive, and capable of balancing strategic leadership with hands-on execution in a fast-paced environment.
- Engaged leader committed to building culture, mentoring talent, and developing scalable Clinical QA capabilities.
See All 180+ Clinical Director Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Clinical Director JobsClinical Director Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Clinical Director Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
- Takeda Pharmaceuticals16
- Merck6
- Alkermes6
- AbbVie4
- Merck KGaA4
Top Industries Hiring
- Biotechnology & Pharmaceuticals14
- Science & Research7
- Healthcare & Medical Services7
- Medical Devices2
- Staffing & Recruiting2
What Massachusetts Employers Look For
The qualifications that appear most often in clinical director jobs across Massachusetts.
- Active Massachusetts clinical license in a relevant field such as nursing, social work, or psychology
- Master's degree or higher in healthcare administration, nursing, social work, or a related clinical field
- Minimum five years of clinical practice experience with demonstrated progression into leadership roles
- Proven experience managing clinical staff, budgets, and regulatory compliance in a Massachusetts healthcare setting
- Familiarity with Massachusetts Department of Public Health regulations and Joint Commission standards
- Strong record of quality improvement initiatives and outcomes management in an accredited clinical environment
Clinical Director Jobs in Massachusetts: Frequently Asked Questions
How do you become a clinical director in Massachusetts?
Becoming a clinical director in Massachusetts typically requires an active state-issued license in your clinical discipline, obtained through the Massachusetts Board of Registration in the relevant profession, such as Nursing, Social Work, or Psychology. Most roles also require a master's degree and several years of progressive clinical and supervisory experience. Credentials like a Nursing Home Administrator license from the Massachusetts Board of Registration of Nursing Home Administrators may apply in long-term care settings.
Which companies hire clinical directors in Massachusetts?
Employers hiring clinical directors in Massachusetts right now include Takeda Pharmaceuticals, Merck, and Alkermes, based on current listings on Migrate Mate as of August 2026. Massachusetts's dense network of academic medical centers, community health centers, and behavioral health agencies means clinical director roles appear consistently across both large systems and mission-driven nonprofits throughout the state.
Which Massachusetts cities have the most clinical director jobs?
The cities with the most clinical director openings in Massachusetts are Boston, Cambridge, and Waltham. Boston dominates due to its concentration of academic medical centers, specialty hospitals, and large health systems, while Worcester and Springfield reflect strong regional healthcare infrastructure anchored by institutions like UMass Memorial Health and Baystate Health that generate steady clinical leadership demand outside the Greater Boston area.
Are there remote clinical director jobs in Massachusetts?
Yes, but they're rare. Clinical director roles are inherently hands-on, requiring direct oversight of staff, patients, and facility operations, which limits remote work. About 61% of clinical director openings tied to Massachusetts are remote or hybrid as of August 2026, and these tend to be concentrated in utilization review, case management leadership, or telehealth program direction where the supervisory work is documentation- and coordination-heavy rather than floor-based.
How can I get hired as a clinical director in Massachusetts with little or no experience?
The most realistic entry path is moving into a clinical supervisor or assistant director role first, which is how most clinical directors in Massachusetts build their credentials. Large Massachusetts employers like Mass General Brigham and Beth Israel Lahey Health offer formal clinical leadership development programs and internal promotion tracks. Roles such as charge nurse, clinical team lead, or care coordination manager are common stepping stones. A master's degree in healthcare administration or a relevant clinical field, combined with a current Massachusetts clinical license, gives candidates a strong competitive edge when making that first leadership move.
Where can I find and apply to clinical director jobs in Massachusetts?
You can find and apply to clinical director jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings across healthcare systems, behavioral health organizations, and specialty practices. Find roles that fit your experience and specialty and apply directly to the employer. No account creation is needed to search or view listings.
See All 180+ Clinical Director Jobs in Massachusetts
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