Clinical Director Jobs in Massachusetts
Clinical Director jobs in Massachusetts are in strong demand, with openings concentrated in healthcare systems, behavioral health networks, and academic medical centers at levels from program manager to senior executive clinical director. Boston, Worcester, and Springfield anchor most of the hiring, with major employers like Mass General Brigham, UMass Memorial Health, and Baystate Health maintaining consistent clinical director pipelines. The most in-demand specialties include behavioral health, home health and hospice, and rehabilitation services. Find a role that fits below and apply directly.
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Showing 5 of 169+ Clinical Director jobs
Why Sarepta? Why Now?
Sarepta is on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold a leadership position in Duchenne Muscular Dystrophy and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. Our next-generation siRNA platform is focused on chronically administered therapies for neurodegenerative and pulmonary diseases.
We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:
Physical and Emotional Wellness
Financial Wellness
Support for Caregivers
For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us
The Importance of the Role
The Associate Director, Clinical Operations Program Lead, Study Start-up and Feasibility will report to the Director, Patient Recruitment and Start-Up Strategy and lead a team to drive the strategy and implementation of country and site feasibility for our studies and support the internalization of country and site feasibility. Additionally, the candidate will work with early research and other stakeholders to build out the oversight model for Feasibility & Study Start-up. The candidate will drive the study start-up activities and be responsible for oversight of timelines and goals with respect to our clinical studies. The candidate will be responsible for 1) directing and overseeing the success of Sarepta’s clinical trial feasibility process, 2) leading the development of feasibility and start-up strategies including study-specific plans, 3) directing and overseeing the success of the Sarepta’s clinical trial start-up activities, 4) and working with both internal and external vendors.
This is a highly cross-functional position, collaborating with internal teams, CROs, and vendors. The candidate must be comfortable working directly with clinical trial sites.
The contribution of the candidate directly supports the goals of the Development Operations organization under R&D.
This is a great opportunity for an individual with an operational background and innovative mindset to help us accelerate study execution to support Sarepta’s goal of Patient’s First.
The Opportunity to Make a Difference
Primary Responsibilities Include:
- Develop and implement the feasibility and start-up strategies to support the success of Sarepta clinical studies.
- Gather cross-functional, country-level input to inform robust feasibility strategies.
- Develop and manage integrated feasibility and site start-up timelines, and report on progress, including plans to address potential timing risks or gaps.
- Establish study specific meeting series to review clinical trial feasibility data and start-up activities with study leads, MSLs, and the CRO. The candidate will report metrics to larger teams including senior management.
- Lead calls with Sarepta and the CRO to manage feasibility and study start-up activities and ensure the study timelines are achieved.
- Oversee study feasibility activities including country, site, and investigator selection for participation in Sarepta-lead studies.
- Foster a culture of innovation by developing new ideas and programs to advance feasibility and support departmental growth.
- Provide guidance and mentoring to junior members of the Study Start-up and Feasibility Team.
- Create reporting tools to measure ongoing activities and other key performance, quality, and effectiveness indicators.
- Partner with Clinical Operations and CRO teams, and other key stakeholders to implement innovative feasibility efforts including collection of data within CTMS.
- Support and or lead the development of Charters or SOPs as it relates to Study Start-up and Feasibility.
- May have direct reports.
More about You
Desired Education and Skills:
- BA / BS degree in a related field; 10+ years related experience in the pharmaceutical or biotech industry within a clinical operations or project management role or similar
- Experience in clinical study budget planning, and program implementation
- Experience with both direct line management and dotted line reporting
- Experience in developing feasibility questionnaires
- Experience with protocol and ICF development and review
- Experience in clinical study start-up
- Experience with rare disease / difficult to recruit populations a plus
- Experience identifying and managing multiple CROs, vendors, budgets, KPIs.
- Comprehensive regulatory knowledge, including ICH and GCPs
- Exceptional organizational skills and ability to deal with competing priorities
- Strong analytical reasoning and problem-solving ability
- Excellent PowerPoint slide development and presentation skills
- Ability to multi-task, work independently and as part of a multidisciplinary team, exercise sound judgement and escalate issues when necessary
What Now?
We’re always looking for solution-oriented, critical thinkers.
So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
#LI-Hybrid This position is hybrid, you will be expected to work on site at one of Sarepta’s facilities in the United States and/or attend Company-sponsored in-person events from time to time. The targeted salary range for this position is $160,800 - $201,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
Why Sarepta? Why Now?
Sarepta is on an urgent mission: engineer precision genetic medicine for rare diseases that devastate lives and cut futures short. We hold a leadership position in Duchenne Muscular Dystrophy and are building a robust portfolio of programs across muscle, central nervous system, and cardiac diseases. Our next-generation siRNA platform is focused on chronically administered therapies for neurodegenerative and pulmonary diseases.
We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
What Sarepta Offers
At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:
Physical and Emotional Wellness
Financial Wellness
Support for Caregivers
For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us
The Importance of the Role
The Associate Director, Clinical Operations Program Lead, Study Start-up and Feasibility will report to the Director, Patient Recruitment and Start-Up Strategy and lead a team to drive the strategy and implementation of country and site feasibility for our studies and support the internalization of country and site feasibility. Additionally, the candidate will work with early research and other stakeholders to build out the oversight model for Feasibility & Study Start-up. The candidate will drive the study start-up activities and be responsible for oversight of timelines and goals with respect to our clinical studies. The candidate will be responsible for 1) directing and overseeing the success of Sarepta’s clinical trial feasibility process, 2) leading the development of feasibility and start-up strategies including study-specific plans, 3) directing and overseeing the success of the Sarepta’s clinical trial start-up activities, 4) and working with both internal and external vendors.
This is a highly cross-functional position, collaborating with internal teams, CROs, and vendors. The candidate must be comfortable working directly with clinical trial sites.
The contribution of the candidate directly supports the goals of the Development Operations organization under R&D.
This is a great opportunity for an individual with an operational background and innovative mindset to help us accelerate study execution to support Sarepta’s goal of Patient’s First.
The Opportunity to Make a Difference
Primary Responsibilities Include:
- Develop and implement the feasibility and start-up strategies to support the success of Sarepta clinical studies.
- Gather cross-functional, country-level input to inform robust feasibility strategies.
- Develop and manage integrated feasibility and site start-up timelines, and report on progress, including plans to address potential timing risks or gaps.
- Establish study specific meeting series to review clinical trial feasibility data and start-up activities with study leads, MSLs, and the CRO. The candidate will report metrics to larger teams including senior management.
- Lead calls with Sarepta and the CRO to manage feasibility and study start-up activities and ensure the study timelines are achieved.
- Oversee study feasibility activities including country, site, and investigator selection for participation in Sarepta-lead studies.
- Foster a culture of innovation by developing new ideas and programs to advance feasibility and support departmental growth.
- Provide guidance and mentoring to junior members of the Study Start-up and Feasibility Team.
- Create reporting tools to measure ongoing activities and other key performance, quality, and effectiveness indicators.
- Partner with Clinical Operations and CRO teams, and other key stakeholders to implement innovative feasibility efforts including collection of data within CTMS.
- Support and or lead the development of Charters or SOPs as it relates to Study Start-up and Feasibility.
- May have direct reports.
More about You
Desired Education and Skills:
- BA / BS degree in a related field; 10+ years related experience in the pharmaceutical or biotech industry within a clinical operations or project management role or similar
- Experience in clinical study budget planning, and program implementation
- Experience with both direct line management and dotted line reporting
- Experience in developing feasibility questionnaires
- Experience with protocol and ICF development and review
- Experience in clinical study start-up
- Experience with rare disease / difficult to recruit populations a plus
- Experience identifying and managing multiple CROs, vendors, budgets, KPIs.
- Comprehensive regulatory knowledge, including ICH and GCPs
- Exceptional organizational skills and ability to deal with competing priorities
- Strong analytical reasoning and problem-solving ability
- Excellent PowerPoint slide development and presentation skills
- Ability to multi-task, work independently and as part of a multidisciplinary team, exercise sound judgement and escalate issues when necessary
What Now?
We’re always looking for solution-oriented, critical thinkers.
So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
#LI-Hybrid This position is hybrid, you will be expected to work on site at one of Sarepta’s facilities in the United States and/or attend Company-sponsored in-person events from time to time. The targeted salary range for this position is $160,800 - $201,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity. Candidates must be authorized to work in the U.S. Sarepta Therapeutics offers a competitive compensation and benefit package. Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.
See All 169+ Clinical Director Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
Find Clinical Director JobsClinical Director Jobs by City in Massachusetts
Where Massachusetts roles are concentrated, by current openings.
Clinical Director Job Market in Massachusetts
A snapshot from current Massachusetts openings, updated as new roles post.
Who's Hiring
- Takeda Pharmaceuticals11
- AbbVie10
- Alkermes5
- AstraZeneca4
- Amylyx Pharmaceuticals4
Top Industries Hiring
- Healthcare & Medical Services
- Biotechnology & Pharmaceuticals
- Science & Research
- Education
- Staffing & Recruiting
What Massachusetts Employers Look For
The qualifications that appear most often in clinical director jobs across Massachusetts.
- Active Massachusetts clinical license in a relevant field such as nursing, social work, or psychology
- Master's degree or higher in healthcare administration, nursing, social work, or a related clinical field
- Minimum five years of clinical practice experience with demonstrated progression into leadership roles
- Proven experience managing clinical staff, budgets, and regulatory compliance in a Massachusetts healthcare setting
- Familiarity with Massachusetts Department of Public Health regulations and Joint Commission standards
- Strong record of quality improvement initiatives and outcomes management in an accredited clinical environment
Clinical Director Jobs in Massachusetts: Frequently Asked Questions
How do you become a clinical director in Massachusetts?
Becoming a clinical director in Massachusetts typically requires an active state-issued license in your clinical discipline, obtained through the Massachusetts Board of Registration in the relevant profession, such as Nursing, Social Work, or Psychology. Most roles also require a master's degree and several years of progressive clinical and supervisory experience. Credentials like a Nursing Home Administrator license from the Massachusetts Board of Registration of Nursing Home Administrators may apply in long-term care settings.
Which companies hire clinical directors in Massachusetts?
Employers hiring clinical directors in Massachusetts right now include Takeda Pharmaceuticals, AbbVie, and Alkermes, based on current listings on Migrate Mate as of October 2026. Massachusetts's dense network of academic medical centers, community health centers, and behavioral health agencies means clinical director roles appear consistently across both large systems and mission-driven nonprofits throughout the state.
Which Massachusetts cities have the most clinical director jobs?
The cities with the most clinical director openings in Massachusetts are Boston, Waltham, and Cambridge. Boston dominates due to its concentration of academic medical centers, specialty hospitals, and large health systems, while Worcester and Springfield reflect strong regional healthcare infrastructure anchored by institutions like UMass Memorial Health and Baystate Health that generate steady clinical leadership demand outside the Greater Boston area.
Are there remote clinical director jobs in Massachusetts?
Yes, but they're rare. Clinical director roles are inherently hands-on, requiring direct oversight of staff, patients, and facility operations, which limits remote work. About 68% of clinical director openings tied to Massachusetts are remote or hybrid as of October 2026, and these tend to be concentrated in utilization review, case management leadership, or telehealth program direction where the supervisory work is documentation- and coordination-heavy rather than floor-based.
How can I get hired as a clinical director in Massachusetts with little or no experience?
The most realistic entry path is moving into a clinical supervisor or assistant director role first, which is how most clinical directors in Massachusetts build their credentials. Large Massachusetts employers like Mass General Brigham and Beth Israel Lahey Health offer formal clinical leadership development programs and internal promotion tracks. Roles such as charge nurse, clinical team lead, or care coordination manager are common stepping stones. A master's degree in healthcare administration or a relevant clinical field, combined with a current Massachusetts clinical license, gives candidates a strong competitive edge when making that first leadership move.
Where can I find and apply to clinical director jobs in Massachusetts?
You can find and apply to clinical director jobs in Massachusetts on Migrate Mate, which lists current Massachusetts openings across healthcare systems, behavioral health organizations, and specialty practices. Find roles that fit your experience and specialty and apply directly to the employer. No account creation is needed to search or view listings.
See All 169+ Clinical Director Jobs in Massachusetts
Find roles in Massachusetts that match your experience and apply in just a few clicks.
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