Nurse Practitioner Or Physician Assistant Jobs in North Carolina
Nurse Practitioner Or Physician Assistant jobs in North Carolina are in strong and steady demand, concentrated in primary care, urgent care, and specialty settings across health systems, federally qualified health centers, and outpatient clinics, with openings ranging from new graduates through experienced senior clinicians. Charlotte, Raleigh, and the Triad area anchor most of the hiring activity, with large employers like Atrium Health, Duke Health, and UNC Health consistently posting across multiple specialties. Cardiology, orthopedics, and family medicine draw the most consistent openings statewide. Find a role that fits below and apply directly.
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Showing 5 of 138+ Nurse Practitioner Or Physician Assistant jobs
About Us
One Medical is a primary care solution challenging the industry status quo by making quality care more affordable, accessible and enjoyable. But this isn't your average doctor's office. We're on a mission to transform healthcare, which means improving the experience for everyone involved - from patients and providers to employers and health networks. Our seamless in-office and 24/7 virtual care services, on-site labs, and programs for preventive care, chronic care management, common illnesses and mental health concerns have been delighting people for the past fifteen years.
In February 2023 we marked a milestone when One Medical joined Amazon. Together, we look to deliver exceptional health care to more consumers, employers, care team members, and health networks to achieve better health outcomes. As we continue to grow and seek to impact more lives, we're building a diverse, driven and empathetic team, while working hard to cultivate an environment where everyone can thrive.
Employment type:
- "Casual Employee" (per diem, hourly clinician role)
- 16-23 patient care hours per week
Location:
- Seeing patients across multiple offices in Durham, NC
- Weekly schedule will include hours at several clinics in North Carolina
What you'll be working on:
- Seeing patients with a broad array of patient needs; conducting a mix of acute, chronic, and well visits (not a panel-building role)
- Treating patients in-office as well as conducting occasional tele-health visits
- Ongoing collaboration with in-office teammates via daily huddles, as well as with virtual clinical teams
- Utilization of your specific clinical training and opportunities to perform in-office procedures
Education, licenses, and experiences required for this role:
- At least 2 years of primary care experience required.
- Currently licensed or ability to obtain licensure in the state of North Carolina
- The ability to build successful relationships with team members and communicate effectively both 1-on-1 and in groups.
- Can thrive in a fast-growing, mission driven organization focused on using data to improve patient outcomes.
- Board Certification.
One Medical providers also demonstrate:
- A passion for human-centered primary care
- The ability to successfully communicate with and provide care to individuals of all backgrounds
- The ability to effectively use technology to deliver high quality care
- Clinical proficiency in evidence-based primary care
- The desire to be an integral part of a team dedicated to changing healthcare delivery
- An openness to feedback and reflection to gain productive insight into strengths and weaknesses
- The ability to confidently navigate uncertain situations with both patients and colleagues
- Readiness to adapt personal and interpersonal behavior to meet the needs of our patients
Casual/Per Diem/Locums Providers receive
- Malpractice Insurance - Malpractice fees to insure your practice at One Medical is covered 100%
- UpToDate Subscription - An evidence-based clinical research tool
- One Medical Issued laptop (to allow for secure access to our EHR)
- Sick Time PTO eligible in accordance with local requirement
This is an hourly role based in Durham, NC
One Medical is committed to fair and equitable compensation practices.
The hourly rate for this role is $75.00 per hour. Final determination of starting pay may vary based on factors such as practice experience and patient care schedule. Additional pay may be determined for those candidates that exceed these specified qualifications and requirements. The total compensation package for this position may also include benefits. For more information, visit https://www.onemedical.com/careers/
One Medical offers a robust benefits package designed to aid your health and wellness. All regular team members working 24+ hours per week and their dependents are eligible for benefits starting on the team member's date of hire:
Taking care of you today
- Paid sabbatical for every five years of service
- Free One Medical memberships for yourself, your friends and family
- Employee Assistance Program - Free confidential services for team members who need help with stress, anxiety, financial planning, and legal issues
- Competitive Medical, Dental and Vision plans
- Pre-Tax commuter benefits
- PTO cash outs - Option to cash out up to 40 accrued hours per year
Protecting your future for you and your family
- 401K match
- Credit towards emergency childcare
- Company paid maternity and paternity leave
- Paid Life Insurance - One Medical pays 100% of the cost of Basic Life Insurance
- Disability insurance - One Medical pays 100% of the cost of Short Term and Long Term Disability Insurance
In addition to the comprehensive benefits package outlined above, practicing clinicians also receive
- Malpractice Insurance - Malpractice fees to insure your practice at One Medical is covered 100%.
- UpToDate Subscription - An evidence-based clinical research tool
- Continuing Medical Education (CME) - Receive an annual stipend for continuing medical education
- Rounds - Providers end patient care one hour early each week to participate in this shared learning experience
- Discounted rate to attend One Medical's Annual REAL primary care conference
One Medical is an equal opportunity employer, and we encourage qualified applicants of every background, ability, and life experience to contact us about appropriate employment opportunities.
One Medical participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S. Please refer to the E-Verification Poster and Right to Work Poster for additional information.
About Us
One Medical is a primary care solution challenging the industry status quo by making quality care more affordable, accessible and enjoyable. But this isn't your average doctor's office. We're on a mission to transform healthcare, which means improving the experience for everyone involved - from patients and providers to employers and health networks. Our seamless in-office and 24/7 virtual care services, on-site labs, and programs for preventive care, chronic care management, common illnesses and mental health concerns have been delighting people for the past fifteen years.
In February 2023 we marked a milestone when One Medical joined Amazon. Together, we look to deliver exceptional health care to more consumers, employers, care team members, and health networks to achieve better health outcomes. As we continue to grow and seek to impact more lives, we're building a diverse, driven and empathetic team, while working hard to cultivate an environment where everyone can thrive.
Employment type:
- "Casual Employee" (per diem, hourly clinician role)
- 16-23 patient care hours per week
Location:
- Seeing patients across multiple offices in Durham, NC
- Weekly schedule will include hours at several clinics in North Carolina
What you'll be working on:
- Seeing patients with a broad array of patient needs; conducting a mix of acute, chronic, and well visits (not a panel-building role)
- Treating patients in-office as well as conducting occasional tele-health visits
- Ongoing collaboration with in-office teammates via daily huddles, as well as with virtual clinical teams
- Utilization of your specific clinical training and opportunities to perform in-office procedures
Education, licenses, and experiences required for this role:
- At least 2 years of primary care experience required.
- Currently licensed or ability to obtain licensure in the state of North Carolina
- The ability to build successful relationships with team members and communicate effectively both 1-on-1 and in groups.
- Can thrive in a fast-growing, mission driven organization focused on using data to improve patient outcomes.
- Board Certification.
One Medical providers also demonstrate:
- A passion for human-centered primary care
- The ability to successfully communicate with and provide care to individuals of all backgrounds
- The ability to effectively use technology to deliver high quality care
- Clinical proficiency in evidence-based primary care
- The desire to be an integral part of a team dedicated to changing healthcare delivery
- An openness to feedback and reflection to gain productive insight into strengths and weaknesses
- The ability to confidently navigate uncertain situations with both patients and colleagues
- Readiness to adapt personal and interpersonal behavior to meet the needs of our patients
Casual/Per Diem/Locums Providers receive
- Malpractice Insurance - Malpractice fees to insure your practice at One Medical is covered 100%
- UpToDate Subscription - An evidence-based clinical research tool
- One Medical Issued laptop (to allow for secure access to our EHR)
- Sick Time PTO eligible in accordance with local requirement
This is an hourly role based in Durham, NC
One Medical is committed to fair and equitable compensation practices.
The hourly rate for this role is $75.00 per hour. Final determination of starting pay may vary based on factors such as practice experience and patient care schedule. Additional pay may be determined for those candidates that exceed these specified qualifications and requirements. The total compensation package for this position may also include benefits. For more information, visit https://www.onemedical.com/careers/
One Medical offers a robust benefits package designed to aid your health and wellness. All regular team members working 24+ hours per week and their dependents are eligible for benefits starting on the team member's date of hire:
Taking care of you today
- Paid sabbatical for every five years of service
- Free One Medical memberships for yourself, your friends and family
- Employee Assistance Program - Free confidential services for team members who need help with stress, anxiety, financial planning, and legal issues
- Competitive Medical, Dental and Vision plans
- Pre-Tax commuter benefits
- PTO cash outs - Option to cash out up to 40 accrued hours per year
Protecting your future for you and your family
- 401K match
- Credit towards emergency childcare
- Company paid maternity and paternity leave
- Paid Life Insurance - One Medical pays 100% of the cost of Basic Life Insurance
- Disability insurance - One Medical pays 100% of the cost of Short Term and Long Term Disability Insurance
In addition to the comprehensive benefits package outlined above, practicing clinicians also receive
- Malpractice Insurance - Malpractice fees to insure your practice at One Medical is covered 100%.
- UpToDate Subscription - An evidence-based clinical research tool
- Continuing Medical Education (CME) - Receive an annual stipend for continuing medical education
- Rounds - Providers end patient care one hour early each week to participate in this shared learning experience
- Discounted rate to attend One Medical's Annual REAL primary care conference
One Medical is an equal opportunity employer, and we encourage qualified applicants of every background, ability, and life experience to contact us about appropriate employment opportunities.
One Medical participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S. Please refer to the E-Verification Poster and Right to Work Poster for additional information.
See All 138+ Nurse Practitioner Or Physician Assistant Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
Find JobsNurse Practitioner Or Physician Assistant Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Nurse Practitioner Or Physician Assistant Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
- Cone Health23
- Optum22
- Duke Health16
- WakeMed Health & Hospitals13
- Curana Health7
Top Industries Hiring
- Healthcare & Medical Services33
- Staffing & Recruiting3
- Consulting & Professional Services3
- Education1
- Insurance1
What North Carolina Employers Look For
The qualifications that appear most often in nurse practitioner or physician assistant jobs across North Carolina.
- Active North Carolina nurse practitioner or physician assistant license or board certification required
- Master's degree or doctoral degree in nursing or physician assistant studies required
- Board certification from AANP, ANCC, or NCCPA required for clinical practice
- Current DEA registration and North Carolina prescriptive authority for applicable roles
- Minimum one to three years of clinical experience preferred in specialty settings
- Current BLS and ACLS certification required at time of hire
Nurse Practitioner Or Physician Assistant Jobs in North Carolina: Frequently Asked Questions
How do you become a nurse practitioner or physician assistant in North Carolina?
Nurse practitioners in North Carolina must hold a master's or doctoral degree from an accredited program, pass a national certification exam through AANP or ANCC, and obtain licensure through the North Carolina Board of Nursing. Physician assistants must graduate from an accredited PA program, pass the PANCE administered by NCCPA, and register with the North Carolina Medical Board. Both professions require ongoing continuing education and periodic recertification to maintain active status.
Which companies hire nurse practitioner or physician assistants in North Carolina?
Employers hiring nurse practitioner or physician assistants in North Carolina right now include Cone Health, Optum, and Duke Health, based on current listings on Migrate Mate as of August 2026. North Carolina's large integrated health systems, federally qualified health centers, and growing urgent care networks maintain consistent openings across primary care, specialty, and hospital-based practices throughout the state.
Which North Carolina cities have the most nurse practitioner or physician assistant jobs?
The cities with the most nurse practitioner or physician assistant openings in North Carolina are Greensboro, Raleigh, and Durham. Charlotte drives volume through the Atrium Health and Novant Health systems, Raleigh and Durham benefit from the dense concentration of academic medical centers and health networks in the Research Triangle, and Greensboro supports steady demand through regional hospital systems and outpatient specialty groups in the Triad.
Are there remote nurse practitioner or physician assistant jobs in North Carolina?
Yes, but they're rare. The core of nurse practitioner and physician assistant work is hands-on patient care, which requires an in-person clinical setting. About 10% of nurse practitioner or physician assistant openings tied to North Carolina are remote or hybrid as of August 2026, and those roles are almost always in telehealth triage, chronic disease management, or utilization review functions that don't require direct bedside care.
How can I get hired as a nurse practitioner or physician assistant in North Carolina with little or no experience?
The most realistic entry path is applying to new-graduate residency or fellowship programs offered by large North Carolina systems such as UNC Health, Duke Health, and Atrium Health, which run structured transition-to-practice programs specifically for newly licensed clinicians. Candidates with experience as a registered nurse or as a physician assistant student who completed clinical rotations at a North Carolina facility have a strong advantage. Completing rotations in underserved or rural areas through the North Carolina Area Health Education Centers network can also open doors with federally qualified health centers that actively recruit new graduates.
Where can I find and apply to nurse practitioner or physician assistant jobs in North Carolina?
You can find and apply to nurse practitioner or physician assistant jobs in North Carolina on Migrate Mate, which lists current openings from employers actively hiring across the state. Search the listings, find roles that match your specialty and experience level, and apply directly to the ones that fit.
See All 138+ Nurse Practitioner Or Physician Assistant Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
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