Pediatric Nurse Practitioner Jobs in North Carolina
Pediatric Nurse Practitioner jobs in North Carolina are consistently active, with demand concentrated in hospital-based pediatric units, federally qualified health centers, and large multispecialty group practices at every level from new-graduate NP through senior clinical lead. The heaviest hiring is in Charlotte, Raleigh, and Durham, where employers like Atrium Health, Duke Health, and UNC Health maintain well-established pediatric programs. The most sought-after specialties in North Carolina include primary care pediatrics, developmental-behavioral pediatrics, and pediatric urgent care. Find a role that fits below and apply directly.
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Showing 3 of 16+ Pediatric Nurse Practitioner jobs
Description
Become part of an inclusive organization with over 40,000 teammates, whose mission is to improve the health and well-being of the unique communities we serve.
Full-Time | Inpatient & Outpatient | Weekend & Holiday Required
The Department of Pediatrics seeks a full-time Advanced Practice Provider (Nurse Practitioner or Physician Assistant) to join the Division of Pediatric Hematology/Oncology. This position provides comprehensive, evidence-based care to children, adolescents, and young adults with malignant and non-malignant hematologic disorders across inpatient and outpatient settings.
The APP will serve as an essential member of a multidisciplinary academic team and will play an active role in clinical care, education, quality improvement, and participation in clinical research and therapeutic trials.
This position will involve primarily weekend coverage with the possibility of outpatient clinic responsibilities for admissions and follow up visits.
Clinical Responsibilities
Inpatient Care
- Conduct daily rounds in collaboration with attending physicians, fellows, residents, pharmacists, and nursing teams
- Manage acute hematologic, oncologic and bone marrow transplant emergencies (e.g., febrile neutropenia, tumor lysis syndrome, sickle cell pain)
- Perform admission evaluations, ongoing assessments, and discharge planning
- Order and interpret laboratory and diagnostic studies
- Participate in weekend and holiday coverage
Outpatient Care
- Perform independent and collaborative visits under physician supervision, as appropriate
- Manage outpatient oncology patients across the care continuum (active treatment, follow-up, survivorship)
- Provide same-day urgent/symptom-based evaluations to reduce ED utilization
- Manage chemotherapy and supportive care regimens
- Monitor treatment response and manage therapy-related complications
- Provide patient and family education regarding diagnosis, treatment plans, and symptom management
- Conduct chemotherapy education and supportive care counseling for patients and families
- Coordinate care across specialties, infusion services, and external providers
- Document and bill patient encounters in compliance with institutional and regulatory standards
Procedures (within scope of practice)
- Lumbar punctures
- Bone marrow aspirates and biopsies
- Ommaya tap
- Intrathecal chemotherapy administration
- Central line management
Clinical Trials & Research Participation
- Provide direct clinical care to patients enrolled in institutional, cooperative group, and industry-sponsored clinical trials
- Ensure protocol adherence in collaboration with principal investigators and research coordinators
- Perform study-related assessments and documentation
- Assist with eligibility screening and informed consent processes (as permitted by scope and institutional policy)
- Monitor for and report adverse events in accordance with regulatory standards
- Participate in multidisciplinary tumor boards and research meetings
- Contribute to quality improvement initiatives and opportunities for scholarly activity, including presentations and publications
Academic Engagement
- Participate in the education of residents, fellows, nurse practitioner students, and physician assistant students
- Attend and contribute to divisional conferences, case reviews, and morbidity and mortality discussions
- Engage in ongoing professional development and academic scholarship
Schedule
- Full-time position
- Combination of inpatient and outpatient responsibilities
- Weekend and holiday coverage required
Required Qualifications
- Graduate of an accredited Nurse Practitioner or Physician Assistant program
- Current state licensure and national board certification
- DEA registration
- Pediatric clinical experience required
- BLS and PALS certification
Preferred Qualifications
- Experience in pediatric hematology/oncology
- Experience caring for patients enrolled in clinical trials
- Familiarity with research protocols and regulatory requirements
- Experience in academic medical center environment
Core Competencies
- Advanced clinical reasoning in medically complex pediatric populations
- Strong understanding of research integrity and protocol compliance
- Excellent communication and interdisciplinary collaboration skills
- Commitment to family-centered, compassionate care
- Ability to balance clinical productivity with academic engagement
Other Information
Education Requirements:
- Completion of an accredited graduate-level Advanced Practice Provider (APRN or PA) program.
- Licensed as an Advanced Practice Provider (i.e., Nurse Practitioner, Physician Assistant, Clinical Pharmacist Practitioner, Certified Nurse Midwife, Certified Registered Nurse Anesthetist) in the state of North Carolina.
- Board certification if required by the Department. DEA.
- No prior experience required.
- Demonstrated clinical competency.
- Effective leadership skills. Strong interpersonal skills.
- Ability to work independently and collaboratively.
- Demonstrated written and verbal communication and strong analytical skills.
- Effective interaction to ensure the successful care of patients in the clinical setting.
- Documentation in the medical record to substantiate accurate billing.
Job Details
Legal Employer: STATE
Entity: UNC Faculty Physicians
Organization Unit: Pediatric Hematology/Oncology
Work Type: Full Time
Standard Hours Per Week: 40.00
Work Assignment Type: Onsite
Work Schedule: Day Job
Location of Job: US:NC: Chapel Hill
Exempt From Overtime: Exempt: Yes
This is a State position employed by UNC Health Care System with UNC Health benefits. If, however, you are presently an employee of another North Carolina agency and currently participate in TSERS or the ORP, you will be eligible to continue participating in those plans at UNC Health.
Qualified applicants will be considered without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, genetic information, disability, status as a protected veteran or political affiliation.
UNC Health makes reasonable accommodations for applicants' and employees' religious practices and beliefs, as well as applicants and employees with disabilities. All interested applicants are invited to apply for career opportunities. Please email applicant.accommodations@unchealth.unc.edu if you need a reasonable accommodation to search and/or to apply for a career opportunity.
Description
Become part of an inclusive organization with over 40,000 teammates, whose mission is to improve the health and well-being of the unique communities we serve.
Full-Time | Inpatient & Outpatient | Weekend & Holiday Required
The Department of Pediatrics seeks a full-time Advanced Practice Provider (Nurse Practitioner or Physician Assistant) to join the Division of Pediatric Hematology/Oncology. This position provides comprehensive, evidence-based care to children, adolescents, and young adults with malignant and non-malignant hematologic disorders across inpatient and outpatient settings.
The APP will serve as an essential member of a multidisciplinary academic team and will play an active role in clinical care, education, quality improvement, and participation in clinical research and therapeutic trials.
This position will involve primarily weekend coverage with the possibility of outpatient clinic responsibilities for admissions and follow up visits.
Clinical Responsibilities
Inpatient Care
- Conduct daily rounds in collaboration with attending physicians, fellows, residents, pharmacists, and nursing teams
- Manage acute hematologic, oncologic and bone marrow transplant emergencies (e.g., febrile neutropenia, tumor lysis syndrome, sickle cell pain)
- Perform admission evaluations, ongoing assessments, and discharge planning
- Order and interpret laboratory and diagnostic studies
- Participate in weekend and holiday coverage
Outpatient Care
- Perform independent and collaborative visits under physician supervision, as appropriate
- Manage outpatient oncology patients across the care continuum (active treatment, follow-up, survivorship)
- Provide same-day urgent/symptom-based evaluations to reduce ED utilization
- Manage chemotherapy and supportive care regimens
- Monitor treatment response and manage therapy-related complications
- Provide patient and family education regarding diagnosis, treatment plans, and symptom management
- Conduct chemotherapy education and supportive care counseling for patients and families
- Coordinate care across specialties, infusion services, and external providers
- Document and bill patient encounters in compliance with institutional and regulatory standards
Procedures (within scope of practice)
- Lumbar punctures
- Bone marrow aspirates and biopsies
- Ommaya tap
- Intrathecal chemotherapy administration
- Central line management
Clinical Trials & Research Participation
- Provide direct clinical care to patients enrolled in institutional, cooperative group, and industry-sponsored clinical trials
- Ensure protocol adherence in collaboration with principal investigators and research coordinators
- Perform study-related assessments and documentation
- Assist with eligibility screening and informed consent processes (as permitted by scope and institutional policy)
- Monitor for and report adverse events in accordance with regulatory standards
- Participate in multidisciplinary tumor boards and research meetings
- Contribute to quality improvement initiatives and opportunities for scholarly activity, including presentations and publications
Academic Engagement
- Participate in the education of residents, fellows, nurse practitioner students, and physician assistant students
- Attend and contribute to divisional conferences, case reviews, and morbidity and mortality discussions
- Engage in ongoing professional development and academic scholarship
Schedule
- Full-time position
- Combination of inpatient and outpatient responsibilities
- Weekend and holiday coverage required
Required Qualifications
- Graduate of an accredited Nurse Practitioner or Physician Assistant program
- Current state licensure and national board certification
- DEA registration
- Pediatric clinical experience required
- BLS and PALS certification
Preferred Qualifications
- Experience in pediatric hematology/oncology
- Experience caring for patients enrolled in clinical trials
- Familiarity with research protocols and regulatory requirements
- Experience in academic medical center environment
Core Competencies
- Advanced clinical reasoning in medically complex pediatric populations
- Strong understanding of research integrity and protocol compliance
- Excellent communication and interdisciplinary collaboration skills
- Commitment to family-centered, compassionate care
- Ability to balance clinical productivity with academic engagement
Other Information
Education Requirements:
- Completion of an accredited graduate-level Advanced Practice Provider (APRN or PA) program.
- Licensed as an Advanced Practice Provider (i.e., Nurse Practitioner, Physician Assistant, Clinical Pharmacist Practitioner, Certified Nurse Midwife, Certified Registered Nurse Anesthetist) in the state of North Carolina.
- Board certification if required by the Department. DEA.
- No prior experience required.
- Demonstrated clinical competency.
- Effective leadership skills. Strong interpersonal skills.
- Ability to work independently and collaboratively.
- Demonstrated written and verbal communication and strong analytical skills.
- Effective interaction to ensure the successful care of patients in the clinical setting.
- Documentation in the medical record to substantiate accurate billing.
Job Details
Legal Employer: STATE
Entity: UNC Faculty Physicians
Organization Unit: Pediatric Hematology/Oncology
Work Type: Full Time
Standard Hours Per Week: 40.00
Work Assignment Type: Onsite
Work Schedule: Day Job
Location of Job: US:NC: Chapel Hill
Exempt From Overtime: Exempt: Yes
This is a State position employed by UNC Health Care System with UNC Health benefits. If, however, you are presently an employee of another North Carolina agency and currently participate in TSERS or the ORP, you will be eligible to continue participating in those plans at UNC Health.
Qualified applicants will be considered without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, genetic information, disability, status as a protected veteran or political affiliation.
UNC Health makes reasonable accommodations for applicants' and employees' religious practices and beliefs, as well as applicants and employees with disabilities. All interested applicants are invited to apply for career opportunities. Please email applicant.accommodations@unchealth.unc.edu if you need a reasonable accommodation to search and/or to apply for a career opportunity.
See All 16 Pediatric Nurse Practitioner Jobs in North Carolina
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Find JobsPediatric Nurse Practitioner Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Pediatric Nurse Practitioner Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
Top Industries Hiring
- Healthcare & Medical Services
What North Carolina Employers Look For
The qualifications that appear most often in pediatric nurse practitioner jobs across North Carolina.
- Active North Carolina Nurse Practitioner license issued by the North Carolina Board of Nursing
- Board certification as a Pediatric Nurse Practitioner-Primary Care or Acute Care (CPNP)
- Master of Science in Nursing or Doctor of Nursing Practice degree from an accredited program
- Current Basic Life Support and Pediatric Advanced Life Support certifications required
- Experience with pediatric electronic health record systems such as Epic or Cerner preferred
- Ability to collaborate with interdisciplinary care teams in fast-paced pediatric clinical environments
Pediatric Nurse Practitioner Jobs in North Carolina: Frequently Asked Questions
How do you become a pediatric nurse practitioner in North Carolina?
To become a pediatric nurse practitioner in North Carolina, you must earn a graduate-level nursing degree and obtain licensure through the North Carolina Board of Nursing, which requires submitting an application, passing a background check, and holding national certification from a recognized credentialing body such as PNCB or ANCC. Most North Carolina employers require the Certified Pediatric Nurse Practitioner credential before hire. The Board of Nursing also requires NPs to hold prescriptive authority approval to manage medications independently.
How much do pediatric nurse practitioners make in North Carolina?
Pediatric nurse practitioners in North Carolina earn a median of about $128,990 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $103,530 for the lowest 10% to over $164,320 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire pediatric nurse practitioners in North Carolina?
Employers hiring pediatric nurse practitioners in North Carolina right now include UNC Health, Duke Health, and WakeMed, based on current listings on Migrate Mate as of August 2026. North Carolina's large integrated health systems and academic medical centers tend to post the most consistent openings, particularly in the Triangle and Charlotte metro areas.
Which North Carolina cities have the most pediatric nurse practitioner jobs?
Durham, Chapel Hill, and Raleigh have the most pediatric nurse practitioner openings in North Carolina. Charlotte and Raleigh lead because of their large health system headquarters and growing suburban populations driving demand for outpatient pediatric care, while Durham benefits from the concentration of academic medical institutions in the Research Triangle that support specialized and acute pediatric programs.
Are there remote pediatric nurse practitioner jobs in North Carolina?
Yes, but they're rare. Pediatric nurse practitioner work is inherently hands-on and most roles require in-person patient contact. About 0% of pediatric nurse practitioner openings tied to North Carolina are remote or hybrid as of August 2026, with the remote-eligible positions most often found in pediatric telehealth triage or care management roles rather than direct clinical practice.
How can I get hired as a pediatric nurse practitioner in North Carolina with little or no experience?
The most realistic entry path is a new-graduate NP residency or fellowship program, and several North Carolina health systems run these specifically for early-career nurse practitioners. Duke Health and UNC Health both offer structured NP transition-to-practice programs that accept candidates with limited post-certification experience. Applying to pediatric urgent care or school-based health clinic roles can also serve as a bridge, and holding an active North Carolina NP license with prescriptive authority approval strengthens any new-grad application significantly.
Where can I find and apply to pediatric nurse practitioner jobs in North Carolina?
You can find and apply to pediatric nurse practitioner jobs in North Carolina on Migrate Mate, which lists current North Carolina openings across health systems, outpatient clinics, and specialty practices. Find roles that fit your experience and specialty focus and apply directly to the ones that match.
See All 16 Pediatric Nurse Practitioner Jobs in North Carolina
Find roles in North Carolina that match your experience and apply in just a few clicks.
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