Pediatric Nurse Practitioner Jobs in Missouri
Pediatric Nurse Practitioner jobs in Missouri are concentrated in Kansas City, St. Louis, and Springfield, where large health systems such as Children's Mercy Kansas City, BJC HealthCare, and CoxHealth maintain steady demand for advanced practice pediatric clinicians. The busiest specialties include primary care pediatrics, developmental and behavioral health, and pediatric urgent care, with openings at every level from new graduate NPs to experienced specialists in complex chronic disease management. Missouri's pediatric healthcare infrastructure, anchored by nationally recognized children's hospitals, keeps this among the most active markets in the Midwest for this credential. Scan the live roles below and apply to whichever ones fit.
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Children’s Mercy is in the heart of Kansas City – a metro abounding in cultural experiences, vibrant communities and thriving businesses. This is where our patients and families live, work and play. This is a community that has embraced our hospital and we strive to say thanks by giving back. As a leader in children’s health, we engage in meaningful programs and partnerships throughout the region so that we can improve the lives of children beyond the walls of our hospital.
The Nephrology APRN I will work collaboratively with an interdisciplinary team to provide care to patients with both chronic and acute renal care needs across inpatient and outpatient settings. Clinical responsibilities include the evaluation and management of patients with end-stage renal disease requiring dialysis and kidney transplantation, fluid and electrolyte disorders, acute kidney injury, chronic kidney disease, glomerulonephritis, hypertension, nephrotic syndrome, and others. The APRN I will support patients throughout the continuum of care, including hospitalization, transition to outpatient management, and longitudinal follow-up.
The APRN I will also participate in beginning leadership activities, evidence-based practice, quality improvement initiatives, research, and organizational development efforts with the support and direction of APP leadership.
Upon completion of orientation, the APRN I will function as an integral member of an interprofessional care team, collaborating with physicians, advanced practice providers, nurses, pharmacists, social workers, dietitians, and allied health professionals to deliver high-quality care to pediatric nephrology patients.
The Advanced Practice Registered Nurse I (APRN-I) provides comprehensive, evidence-based advanced practice nursing to address the physiologic, psychosocial, and developmental needs of patients and families within the framework of the collaborative practice agreement. The APRN-I participates in beginning leadership, evidenced-based practice/ research, and organizational development activities with the support and direction of an experienced APRN mentor.
At Children’s Mercy, we are committed to ensuring that everyone feels welcomed within our walls. A successful candidate for this position will join us as we strive to create a workplace that reflects the community we serve, as well as our core values of kindness, curiosity, inclusion, team and integrity.
Additionally, it’s important to us that we remain transparent with all potential job candidates. Because we value the safety of the patients and families we serve, as well as the Children’s Mercy staff, we want to let you know that the seasonal influenza vaccine is a condition of employment for all employees in our organization. New employees must be willing to be vaccinated if found non-immune to measles, mumps, rubella (MMR) and chicken pox (varicella) and/or without evidence of tetanus, diphtheria, acellular pertussis (Tdap) vaccination since 2005. If you are selected for this position, you will be asked to supply your immunization records as proof of vaccination. If you and have any concerns about receiving these vaccines, medical and/or religious exemptions can be further discussed with Human Resources.
- Master's Degree and 1-2 years experience 1-2 years pediatric APRN experience with Masters. Exceptions considered on a case-by-case basis within preferred specialty. or
- Doctorate in Nursing Practice (DNP) - preferred and 1-2 years experience 1 year pediatric APRN experience. Exceptions considered on a case-by-case basis within preferred specialty.
- One of the following: Licensed RN - Kansas, Registered Nurse Multistate License Kansas required upon hire
- One of the following: Licensed RN - MO, Registered Nurse Multistate License Missouri required upon hire
- RN Compact license for all states besides KS and MO
- APRN board certification congruent with population and practice setting (see policy statement: Advanced Practice Registered Nurse Roles and Practice Setting) Required Upon Hire
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Acute Care PNP will be required
- Will have two years to be enrolled in a program and five years to complete the program
- OR Certified Nurse Practitioner (CNP) in MO & KS Required Upon Hire
- Refer to Nursing and Advanced Practice Provider Licensure and Certification policy for required Life Support Certifications Required Upon Hire
- Specialty Certification relevant to unit’s patient population (determined by Nurse Manager/Director) Preferred
CM is committed to creating a workforce that supports the diverse backgrounds of our patients and families. We know that our greatest strengths come from the people who make up our team, so we hire great people from a wide variety of backgrounds, not just because it’s the right thing to do, but because it makes our hospital stronger and our patient care more compassionate.
If you share our values and our enthusiasm for service, you will find a home at CM. In recruiting for our team, we welcome the unique contributions that you can bring, including education, ideas, culture, and beliefs.
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Find JobsPediatric Nurse Practitioner Jobs by City in Missouri
Where Missouri roles are concentrated, by current openings.
Pediatric Nurse Practitioner Job Market in Missouri
A snapshot from current Missouri openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
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- Healthcare & Medical Services
What Missouri Employers Look For
The qualifications that appear most often in pediatric nurse practitioner jobs across Missouri.
- Active Missouri licensure as an Advanced Practice Registered Nurse with pediatric NP certification
- National certification from PNCB or AANP in pediatric primary or acute care
- Master of Science in Nursing or Doctor of Nursing Practice from an accredited program
- Minimum two years of clinical experience in a pediatric outpatient or inpatient setting
- Current BLS and PALS certification required at time of hire
- Ability to prescribe medications under a Missouri collaborative practice agreement with a supervising physician
Pediatric Nurse Practitioner Jobs in Missouri: Frequently Asked Questions
How do you become a pediatric nurse practitioner in Missouri?
To become a pediatric nurse practitioner in Missouri, you must earn a graduate-level nursing degree, complete a pediatric NP program, pass a national certification exam through PNCB or AANP, then apply for Advanced Practice Registered Nurse licensure through the Missouri State Board of Nursing. Missouri also requires a collaborative practice arrangement with a physician for prescriptive authority. Most Missouri employers expect certification before your start date.
How much do pediatric nurse practitioners make in Missouri?
Pediatric nurse practitioners in Missouri earn a median of about $129,930 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $100,650 for the lowest 10% to over $162,060 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire pediatric nurse practitioners in Missouri?
Companies currently hiring pediatric nurse practitioners in Missouri include Children's Mercy Hospitals & Clinics, BJC HealthCare, and Washington University in St. Louis, per current listings on Migrate Mate as of October 2026. Missouri's pediatric hiring is especially concentrated among large integrated health systems and freestanding children's hospitals that operate ambulatory care networks across the state.
Which Missouri cities have the most pediatric nurse practitioner jobs?
Kansas City, St. Louis, and Columbia have the most pediatric nurse practitioner openings in Missouri. Kansas City leads because of Children's Mercy's broad outpatient network, St. Louis draws volume through BJC HealthCare and SSM Health's children's services, and Springfield's CoxHealth system anchors demand in the southwest corner of the state.
Are there remote pediatric nurse practitioner jobs in Missouri?
Yes, but they're rare. Pediatric nurse practitioner work is largely hands-on, so most roles require an in-person clinical presence. About 0% of pediatric nurse practitioner openings tied to Missouri are remote or hybrid as of October 2026, and those positions are almost exclusively in pediatric telehealth triage or care management roles rather than primary or acute care.
How can I get hired as a pediatric nurse practitioner in Missouri with little or no experience?
The most realistic entry path is applying to new-graduate NP residency or fellowship programs, with Children's Mercy Kansas City running one of the most established pediatric NP transition-to-practice programs in the region. BJC HealthCare and SSM Health also post new-grad NP roles in pediatric primary care clinics. Candidates who hold current PNCB certification, have pediatric clinical hours from their NP program, and can document preceptorship at a Missouri children's facility consistently receive the strongest consideration.
Where can I find and apply to pediatric nurse practitioner jobs in Missouri?
You can find and apply to pediatric nurse practitioner jobs in Missouri on Migrate Mate, which lists current Missouri openings from employers across the state. Search the roles available, identify the ones that match your credentials and preferred location, and apply directly to whichever positions fit your background.
See All 15 Pediatric Nurse Practitioner Jobs in Missouri
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