Oncology Registered Nurse Jobs in North Carolina

Oncology Registered Nurse jobs in North Carolina are consistently active, concentrated in major academic medical centers, large nonprofit hospital systems, and outpatient infusion networks, with openings at every level from new graduate to oncology nurse navigator. The heaviest hiring is in Charlotte, Durham, and Raleigh-Chapel Hill, where employers like Atrium Health, Duke University Health System, and UNC Health maintain some of the largest oncology programs in the Southeast. The most in-demand specialties are infusion nursing, bone marrow transplant, and radiation oncology care coordination. Find a role that fits below and apply directly.

Find Jobs

Overview

Open roles115+
Top employerAdvocate Aurora Health
Top cityCharlotte, NC
Cities hiring25
Work type100% On-site
Top industryHealthcare

Showing 5 of 115+ Oncology Registered Nurse jobs

UNC Health
RN Clinical Nurse II - Oncology Infusion Garner
We won't show you this job again
UNC Health
New 19h ago
RN Clinical Nurse II - Oncology Infusion Garner
UNC Health
Garner, North Carolina
Clinical Support
Healthcare Administration
Human Resources
$34.22 - $48.38/hr
On-Site
BLS Certification
10,000+

Have you applied for this role?

Iredell Memorial Hospital Incorporated
Registered Nurse (RN) Renal / Oncology | Night Shift
We won't show you this job again
Iredell Memorial Hospital Incorporated
Added 1d ago
Registered Nurse (RN) Renal / Oncology | Night Shift
Iredell Memorial Hospital Incorporated
Statesville, North Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification

Have you applied for this role?

Iredell Memorial Hospital Incorporated
Registered Nurse (RN) Oncology Unit | Day Shift
We won't show you this job again
Iredell Memorial Hospital Incorporated
Added 1d ago
Registered Nurse (RN) Oncology Unit | Day Shift
Iredell Memorial Hospital Incorporated
Statesville, North Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification

Have you applied for this role?

V
Travel RN Oncology
We won't show you this job again
V
Added 1d ago
Travel RN Oncology
Voyage Health
Asheville, North Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
$1,893 - $1,993/yr

Have you applied for this role?

Atrium Health
Registered Nurse (RN) - New Graduate - Oncology
We won't show you this job again
Atrium Health
Added 1d ago
Registered Nurse (RN) - New Graduate - Oncology
Atrium Health
Winston-Salem, North Carolina
Healthcare Administration
Nursing
Patient Services & Wellbeing
$38.2 - $57.3/hr
BLS Certification
10,000+

Have you applied for this role?

See All 115+ Oncology Registered Nurse Jobs in North Carolina

Find roles in North Carolina that match your experience and apply in just a few clicks.

Find Jobs

Oncology Registered Nurse Jobs by City in North Carolina

Where North Carolina roles are concentrated, by current openings.

Charlotte
31 jobs
Winston-Salem
18 jobs
Raleigh
13 jobs
Chapel Hill
7 jobs
Greenville
5 jobs
Statesville
4 jobs
Hickory
3 jobs
Matthews
3 jobs
Asheville
3 jobs

Oncology Registered Nurse Job Market in North Carolina

A snapshot from current North Carolina openings, updated as new roles post.

Who's Hiring

  • Advocate Aurora Health
    Advocate Aurora Health27
  • Atrium Health
    Atrium Health26
  • UNC Health
    UNC Health17
  • Novant Health
    Novant Health11
  • Duke Health
    Duke Health8

Top Industries Hiring

  • Healthcare & Medical Services

What North Carolina Employers Look For

The qualifications that appear most often in oncology registered nurse jobs across North Carolina.

  • Active North Carolina RN license or multistate compact license recognized in North Carolina
  • Associate or bachelor of science in nursing degree from an accredited program
  • Current BLS certification required, with ACLS preferred for many oncology units
  • One or more years of oncology or medical-surgical nursing experience in an acute care setting
  • OCN certification preferred or required for senior and specialized oncology positions
  • Familiarity with chemotherapy administration protocols and electronic health record systems

Oncology Registered Nurse Jobs in North Carolina: Frequently Asked Questions

How do you become a oncology registered nurse in North Carolina?

You become an oncology registered nurse in North Carolina by earning an associate or bachelor of science in nursing, passing the NCLEX-RN, and obtaining an active RN license through the North Carolina Board of Nursing. North Carolina participates in the Nurse Licensure Compact, so nurses licensed in other compact states can practice without a separate state license. From there, most oncology positions require direct patient care experience, and the Oncology Nursing Certification Corporation offers the OCN credential that many North Carolina employers prefer or require for specialized roles.

How much do oncology registered nurses make in North Carolina?

Oncology registered nurses in North Carolina earn a median of about $84,350 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $67,660 for the lowest 10% to over $110,220 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire oncology registered nurses in North Carolina?

Employers hiring oncology registered nurses in North Carolina right now include Advocate Aurora Health, Atrium Health, and UNC Health, based on current listings on Migrate Mate as of August 2026. North Carolina's concentration of National Cancer Institute-designated programs at institutions like Duke Cancer Institute and UNC Lineberger Comprehensive Cancer Center also creates steady openings for specialized oncology nursing roles.

Which North Carolina cities have the most oncology registered nurse jobs?

The cities with the most oncology registered nurse openings in North Carolina are Charlotte, Winston-Salem, and Raleigh. The Charlotte and Raleigh-Durham-Chapel Hill areas anchor most of the volume because of their large integrated health systems and academic medical centers, while smaller cities in the listing benefit from regional cancer centers and community hospital networks that serve growing suburban and rural populations.

Are there remote oncology registered nurse jobs in North Carolina?

Yes, but they're rare. Most oncology nursing work requires direct patient contact for chemotherapy administration, assessment, and procedure support, making fully remote roles the exception rather than the norm. About 0% of oncology registered nurse openings tied to North Carolina are remote or hybrid as of August 2026, and those positions tend to be in oncology care coordination, triage nursing, or telephone symptom management rather than bedside or infusion roles.

How can I get hired as a oncology registered nurse in North Carolina with little or no experience?

The most realistic entry path is applying to a nurse residency or new graduate program at one of North Carolina's large health systems, such as those offered at Atrium Health, Duke University Health System, and UNC Health, which place new RNs in oncology units with structured mentorship. Starting in a medical-surgical or step-down unit at a North Carolina hospital is a well-established lateral path, since those roles build the assessment skills oncology floors expect. Holding an active North Carolina RN license and completing any oncology-specific continuing education through the Oncology Nursing Society strengthens a new candidate's application considerably.

Where can I find and apply to oncology registered nurse jobs in North Carolina?

You can find and apply to oncology registered nurse jobs in North Carolina on Migrate Mate, which lists current openings across the state. Search the listings for roles that match your experience level and preferred location, then apply directly to the ones that fit.

See All 115+ Oncology Registered Nurse Jobs in North Carolina

Find roles in North Carolina that match your experience and apply in just a few clicks.

Find Jobs