Oncology Registered Nurse Jobs in North Carolina
Oncology Registered Nurse jobs in North Carolina are consistently active, concentrated in major academic medical centers, large nonprofit hospital systems, and outpatient infusion networks, with openings at every level from new graduate to oncology nurse navigator. The heaviest hiring is in Charlotte, Durham, and Raleigh-Chapel Hill, where employers like Atrium Health, Duke University Health System, and UNC Health maintain some of the largest oncology programs in the Southeast. The most in-demand specialties are infusion nursing, bone marrow transplant, and radiation oncology care coordination. Find a role that fits below and apply directly.
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Assignment Overview
- Shift: Nights, 3x12hrs
- Hours: 36 hrs/wk
- Start Date: Nov 23, 2026
- Length: 13 weeks
- Openings: 1
Description
American Traveler is hiring a Med/Surg Oncology RN for a night shift position requiring chemotherapy administration experience or willingness to obtain ONS chemo certification.
Details
- Med/Surg Oncology unit caring for patients receiving chemotherapy and biotherapy via IV, PO, or injection
- Patient population includes AKI, sepsis, cancer, septic shock, pain, overdose, malignant neoplasms, ARF, encephalopathy, FTT, diabetic foot ulcers, and heparin drips
- Patient ratio of 1:6, with higher ratios possible during increased census
- Night shift schedule, 3x12 hours, 18:45-07:15
- 13-26 week contract options available
- Every other weekend required
- Call required for prescheduled shifts
- Floating required to similar units and alternate care locations, including inpatient holding in the ED
- Uses PYXIS, EPIC, and SBAR communication systems
- Contract staff may be assigned to a Storm Team or Hurricane Team and required to report during catastrophic events or mass casualty situations
Requirements
- Active NC or compact RN license (pending license/certs accepted at submission)
- BLS certification required
- ONS Fundamentals of Chemotherapy and Immunotherapy Administration certification preferred; willingness to obtain prior to or during assignment required
- 2 years of Med/Surg or relevant RN experience required
- Inpatient setting experience required
- Skills required include colostomy care, accessing ports, blood product administration, central line blood draw, peripheral line care/management, PICC line management, heparin and insulin administration, surgical drains, chest tubes (Emerson/Pleur-evac), nasal cannula, non-invasive airway management, isolation precautions, and wound care/wound vac
- Cardiac monitoring, dysrhythmia interpretation, and EKG testing skills preferred
- Must pass EKG testing prior to start
- Two professional references from a supervisor within the past 2 years required (pending references accepted at submission)
Additional Information
- Administer and monitor chemotherapy and biotherapy treatments for oncology patients
- Provide general medical-surgical nursing care alongside oncology-specific duties
- Onsite training provided for chemotherapy certification if not already obtained
- Unit orientation is 24 hours (2 shifts), with weekly orientation schedule
- Attendance at monthly staff meetings required
- Navy blue and white scrubs required
- First-time travelers are accepted
- Local candidates accepted at a local rate within 50 miles of the facility
- Previous PERM, PRN, or EP employees of Novant Health or New Hanover must wait 12 months before applying as a traveler, with disclosure and facility approval required
- Current travel per diem clinicians at this facility must choose between travel or per diem status, not both
- RTO of 7 days or less can be auto-approved if it does not fall on a holiday; additional RTO requires facility approval and no RTO is allowed during the first week of assignment
- Must work 2 of 3 major holidays
- Travel pairs allowed if placed on different units with separate transportation and schedules
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Find JobsOncology Registered Nurse Jobs by City in North Carolina
Where North Carolina roles are concentrated, by current openings.
Oncology Registered Nurse Job Market in North Carolina
A snapshot from current North Carolina openings, updated as new roles post.
Who's Hiring
- Advocate Aurora Health26

- Atrium Health25

- UNC Health16

- Novant Health12

- Duke Health11

Top Industries Hiring
- Healthcare & Medical Services
What North Carolina Employers Look For
The qualifications that appear most often in oncology registered nurse jobs across North Carolina.
- Active North Carolina RN license or multistate compact license recognized in North Carolina
- Associate or bachelor of science in nursing degree from an accredited program
- Current BLS certification required, with ACLS preferred for many oncology units
- One or more years of oncology or medical-surgical nursing experience in an acute care setting
- OCN certification preferred or required for senior and specialized oncology positions
- Familiarity with chemotherapy administration protocols and electronic health record systems
Oncology Registered Nurse Jobs in North Carolina: Frequently Asked Questions
How do you become a oncology registered nurse in North Carolina?
You become an oncology registered nurse in North Carolina by earning an associate or bachelor of science in nursing, passing the NCLEX-RN, and obtaining an active RN license through the North Carolina Board of Nursing. North Carolina participates in the Nurse Licensure Compact, so nurses licensed in other compact states can practice without a separate state license. From there, most oncology positions require direct patient care experience, and the Oncology Nursing Certification Corporation offers the OCN credential that many North Carolina employers prefer or require for specialized roles.
How much do oncology registered nurses make in North Carolina?
Oncology registered nurses in North Carolina earn a median of about $84,350 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $67,660 for the lowest 10% to over $110,220 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire oncology registered nurses in North Carolina?
Employers hiring oncology registered nurses in North Carolina right now include Advocate Aurora Health, Atrium Health, and UNC Health, based on current listings on Migrate Mate as of October 2026. North Carolina's concentration of National Cancer Institute-designated programs at institutions like Duke Cancer Institute and UNC Lineberger Comprehensive Cancer Center also creates steady openings for specialized oncology nursing roles.
Which North Carolina cities have the most oncology registered nurse jobs?
The cities with the most oncology registered nurse openings in North Carolina are Charlotte, Raleigh, and Chapel Hill. The Charlotte and Raleigh-Durham-Chapel Hill areas anchor most of the volume because of their large integrated health systems and academic medical centers, while smaller cities in the listing benefit from regional cancer centers and community hospital networks that serve growing suburban and rural populations.
Are there remote oncology registered nurse jobs in North Carolina?
Yes, but they're rare. Most oncology nursing work requires direct patient contact for chemotherapy administration, assessment, and procedure support, making fully remote roles the exception rather than the norm. About 0% of oncology registered nurse openings tied to North Carolina are remote or hybrid as of October 2026, and those positions tend to be in oncology care coordination, triage nursing, or telephone symptom management rather than bedside or infusion roles.
How can I get hired as a oncology registered nurse in North Carolina with little or no experience?
The most realistic entry path is applying to a nurse residency or new graduate program at one of North Carolina's large health systems, such as those offered at Atrium Health, Duke University Health System, and UNC Health, which place new RNs in oncology units with structured mentorship. Starting in a medical-surgical or step-down unit at a North Carolina hospital is a well-established lateral path, since those roles build the assessment skills oncology floors expect. Holding an active North Carolina RN license and completing any oncology-specific continuing education through the Oncology Nursing Society strengthens a new candidate's application considerably.
Where can I find and apply to oncology registered nurse jobs in North Carolina?
You can find and apply to oncology registered nurse jobs in North Carolina on Migrate Mate, which lists current openings across the state. Search the listings for roles that match your experience level and preferred location, then apply directly to the ones that fit.
See All 120+ Oncology Registered Nurse Jobs in North Carolina
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