Oncology Registered Nurse Jobs in Illinois
Oncology Registered Nurse jobs in Illinois are concentrated in academic medical centers, comprehensive cancer programs, and large integrated health systems, with demand at every level from new graduate to seasoned infusion or bone marrow transplant nurse. Most hiring is in Chicago, Evanston, and Springfield, where institutions such as Northwestern Memorial Hospital, Rush University Medical Center, and OSF HealthCare maintain active oncology units year-round. Hematology-oncology, radiation oncology nursing, and palliative care support are among the most consistently sought specialties across Illinois. Find a role that fits below and apply directly.
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Hourly Pay Range:
$36.00 - $55.80 - The hourly pay rate offered is determined by a candidate's expertise and years of experience, among other factors.Endeavor Health is currently conducting a comprehensive review of our compensation structure. The new minimum for this role will be adjusted to $37.25 base pay hourly rate beginning with the second paycheck in October.
Position Highlights:
Position: RN - Oncology Unit
Location: Arlington Heights, IL
Full time/Part time: Full Time: 36 hours per week
Hours: 7:00pm - 7:30am (Night shift), Every other weekend
Required Travel: No
What you will do:
Provides patient assessment and collection of health data involving patient, family and other health care providers.
Coordinates patient plan of care to assure interventions are consistent, safe, timely and appropriate.
Communicates clearly and effectively with all customers, in person, on the phone and in writing.
Individualizes patient and family teaching based on a thorough assessment to meet their specific learning needs.
Participates in evaluating quality and effectiveness of nursing practice by participating in quality improvement initiatives.
Maintains professional knowledge in current nursing practice standards, laws and regulations.
What you will need:
Education: Successful completion of an Associate's degree or BSN from an accredited school of nursing
License: Current licensure to practice nursing in the State of Illinois
Certification: Current CPR certification from the American Heart Association
Benefits (For full time or part time positions):
Premium pay such as shift, on call, holiday and more based on an employee’s job (For eligible positions)
Incentive pay for select positions
Opportunity for annual increases based on performance
Career Pathways to Promote Professional Growth and Development
Various Medical, Dental, Pet and Vision options
Tuition Reimbursement
Free Parking
Wellness Program Savings Plan
Health Savings Account Options
Retirement Options with Company Match
Paid Time Off and Holiday Pay
Community Involvement Opportunities
Endeavor Health is a fully integrated healthcare delivery system committed to providing access to quality, vibrant, community-connected care, serving an area of more than 4.2 million residents across six northeast Illinois counties. Our more than 25,000 team members and more than 6,000 physicians aim to deliver transformative patient experiences and expert care close to home across more than 300 ambulatory locations and eight acute care hospitals – Edward (Naperville), Elmhurst, Evanston, Glenbrook (Glenview), Highland Park, Northwest Community (Arlington Heights) Skokie and Swedish (Chicago) – all recognized as Magnet hospitals for nursing excellence. For more information, visit www.endeavorhealth.org.
When you work for Endeavor Health, you will be part of an organization that encourages its employees to achieve career goals and maximize their professional potential.
Please explore our website (www.endeavorhealth.org) to better understand how Endeavor Health delivers on its mission to “help everyone in our communities be their best”.
Endeavor Health is committed to working with and providing reasonable accommodation to individuals with disabilities. Please refer to the main career page for more information.
At Endeavor Health, we are united by a shared commitment to working together to create a culture of connection and belonging—each of us bringing different skills and experiences as we deliver safe, seamless, and personal care. Every person, every time. We are committed to fostering an environment where all team members can be their best, learn, and pursue excellence together.
EOE: Race/Color/Sex/Sexual Orientation/ Gender Identity/Religion/National Origin/Disability/Vets, VEVRRA Federal Contractor.
See All 49 Oncology Registered Nurse Jobs in Illinois
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Find JobsOncology Registered Nurse Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Oncology Registered Nurse Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring



Top Industries Hiring
- Healthcare & Medical Services
- Science & Research
What Illinois Employers Look For
The qualifications that appear most often in oncology registered nurse jobs across Illinois.
- Active Illinois Registered Nurse license issued by the Illinois Department of Financial and Professional Regulation
- Current BLS certification required and ACLS certification preferred by most Illinois oncology employers
- Oncology Nursing Society ONS chemotherapy and biotherapy administration certification preferred
- Minimum one to two years of oncology or medical-surgical nursing experience in an acute care setting
- Proficiency with electronic health record systems commonly used across Illinois hospital networks
- Strong patient education skills with experience supporting oncology patients through complex treatment regimens
Oncology Registered Nurse Jobs in Illinois: Frequently Asked Questions
How do you become a oncology registered nurse in Illinois?
You must first earn an Associate Degree in Nursing or a Bachelor of Science in Nursing, then pass the NCLEX-RN to obtain an active RN license through the Illinois Department of Financial and Professional Regulation. After gaining bedside experience, typically in medical-surgical or infusion settings, you can pursue the Oncology Certified Nurse credential offered by the Oncology Nursing Certification Corporation, which most Illinois employers recognize as the benchmark for oncology practice.
How much do oncology registered nurses make in Illinois?
Oncology registered nurses in Illinois earn a median of about $95,990 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $69,170 for the lowest 10% to over $118,190 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire oncology registered nurses in Illinois?
Companies currently hiring oncology registered nurses in Illinois include Advocate Aurora Health, Northwestern Medicine, and Carle Health, per current listings on Migrate Mate as of August 2026. Illinois's dense network of academic medical centers and regional cancer programs means consistent openings across both major metros and mid-sized communities throughout the state.
Which Illinois cities have the most oncology registered nurse jobs?
Springfield, Chicago, and Winfield have the most oncology registered nurse openings in Illinois. Chicago drives the largest share of listings because of its concentration of National Cancer Institute-designated cancer centers and major academic health systems, while suburban and downstate cities with large regional hospitals, such as those anchored by OSF HealthCare and Carle Health, also generate consistent demand.
Are there remote oncology registered nurse jobs in Illinois?
Yes, but they're rare. About 0% of oncology registered nurse openings tied to Illinois are remote or hybrid as of August 2026, reflecting that most oncology nursing work requires direct patient contact for infusion administration, assessment, and care coordination. The portions of the role most adaptable to remote work are telephone triage, patient navigation, and care management positions within larger Illinois health systems.
How can I get hired as a oncology registered nurse in Illinois with little or no experience?
The most realistic entry path is applying to a nurse residency or new-graduate oncology fellowship at a large Illinois academic health system, with programs at institutions such as Northwestern Memorial, University of Chicago Medicine, and Rush University Medical Center designed specifically for RNs without oncology experience. Gaining initial experience in medical-surgical or infusion nursing at an Illinois community hospital also positions candidates well, and completing the ONS chemotherapy certification course early signals commitment to prospective oncology hiring managers.
Where can I find and apply to oncology registered nurse jobs in Illinois?
You can find and apply to oncology registered nurse jobs in Illinois on Migrate Mate, which lists current Illinois openings across health systems, cancer centers, and outpatient infusion practices. Find roles that fit your experience and specialty area and apply directly from the listings.
See All 49 Oncology Registered Nurse Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
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