Oncology Registered Nurse Jobs in Illinois
Oncology Registered Nurse jobs in Illinois are concentrated in academic medical centers, comprehensive cancer programs, and large integrated health systems, with demand at every level from new graduate to seasoned infusion or bone marrow transplant nurse. Most hiring is in Chicago, Evanston, and Springfield, where institutions such as Northwestern Memorial Hospital, Rush University Medical Center, and OSF HealthCare maintain active oncology units year-round. Hematology-oncology, radiation oncology nursing, and palliative care support are among the most consistently sought specialties across Illinois. Find a role that fits below and apply directly.
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OVERVIEW
The RN for Oncology provides compassionate, culturally sensitive, holistic nursing care to patients in a clinical setting, supporting the Mercyhealth nursing mission, practice values and strategic plan
Schedule: 32 hours/week
Shift: Days
ESSENTIAL DUTIES AND RESPONSIBILITIES
- Utilizes the nursing process and critical thinking in collaboration with interdisciplinary team members in caring for patients.
- Performs assessments, planning, intervention and evaluation of care
- Administers prescribed medications and treatments in accordance with approved nursing techniques, policies and procedures, standards of care, and state laws/practice act as required by care setting.
- Ensures all documentation is accurate and comprehensive in accordance with the established standards of care for documentation at the system and entity levels.
- Develops initiates and executes a patient plan of care according to the patient's individualized needs, as prescribed by the physician and/or hospital policy. Utilizes resources available to teach and support patient and family education. Provides education to the appropriate level of understanding.
- Participates in department or unit performance improvement activities, which may include shared governance.
- Utilizes clinical expertise & guidance to other units/departments in support of the patient's longitudinal plan of care. Acts to resolve systems breakdowns and engages self and others in providing solutions
- Utilizes critical thinking in regard to patient safety and patient experience, manages complex situations and delegates to other staff appropriately. Escalates to the appropriate chain of command as needed.
- Positively influences the professional and organizational environments and shared governance.
- Engages in personal development and supports system-entity opportunities for continuous learning and growth including developing or revising evidence-based practice guidelines.
- Supports and participates in peer review and peer feedback opportunities.
- Participates in the professional nursing continuum
- Clinic and Ambulatory RNs will maintain timely flow of patients, in addition to responding to telephone calls and performs telephone triage of patients.
- Actively participates in a minimum of 1 departmental or unit performance improvement activities, may include shared governance.
EDUCATION AND/OR EXPERIENCE
Graduate of an accredited nursing program.
ADN required upon hire, BSN preferred.
Minimum of 2 years experience required.
CERTIFICATION/LICENSURE
Licensed as an RN in state of practice
Approved CPR/BLS certification required within 90 days
Other certification(s) per unit requirements. For example: ACLS, PALS, PEARS, and NRP
OTHER SKILLS AND ABILITIES
May include color blind test (per department guidelines)
LEVEL OF SUPERVISION
Carries out supervisory responsibilities in accordance with the organization's policies and applicable laws. Responsibilities include training employees; planning, assigning, and directing work; appraising performance; addressing complaints and resolving problems.
SUPERVISES
Supervises nursing support staff as appropriate.
PAY RANGE:
$35.85 - $60.87Mercyhealth is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identify, national origin, disability, or protected veteran status.
Mercyhealth offers competitive pay and a comprehensive benefits package including:
Medical, Dental, Vision
Life & Disability Insurance
FSA/HSA Options
Generous, accruing paid time off
Paid Parental and caregiver leave
Career advancement and educational opportunities
Tuition and certification reimbursement
Certification Reimbursement
Well-being Programs
Employee Discounts
On-Demand Pay
Financial Education
Annual recognition/awards events
Partner appreciation days
Family entertainment/attractions discount
Community service/improvement opportunities
Click here for more details regarding Mercyhealth Careers Benefit Information.
At Mercyhealth, we don’t simply hire people, we empower employee-partners who are passionate about making lives better. As an integrated health system, we deliver exceptional, coordinated across seven hospitals, 85 primary and specialty clinics, and a team of over 7,500 professionals serving northern Illinois and southern Wisconsin.
Mercyhealth has been nationally recognized for our commitment to our people and culture, including:
#1 in the nation on AARP's Best Employers for Workers Over 50
One of Working Mother magazine's 100 Best Companies for Working Mothers
A Top 50 Company and Top 10 Nonprofit for Executive Women
See All 69 Oncology Registered Nurse Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
Find JobsOncology Registered Nurse Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Oncology Registered Nurse Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring
- Advocate Aurora Health12

- Northwestern Medicine11

- Endeavor Health7

- Carle Health4

- OSF HealthCare4

Top Industries Hiring
- Healthcare & Medical Services
- Science & Research
What Illinois Employers Look For
The qualifications that appear most often in oncology registered nurse jobs across Illinois.
- Active Illinois Registered Nurse license issued by the Illinois Department of Financial and Professional Regulation
- Current BLS certification required and ACLS certification preferred by most Illinois oncology employers
- Oncology Nursing Society ONS chemotherapy and biotherapy administration certification preferred
- Minimum one to two years of oncology or medical-surgical nursing experience in an acute care setting
- Proficiency with electronic health record systems commonly used across Illinois hospital networks
- Strong patient education skills with experience supporting oncology patients through complex treatment regimens
Oncology Registered Nurse Jobs in Illinois: Frequently Asked Questions
How do you become a oncology registered nurse in Illinois?
You must first earn an Associate Degree in Nursing or a Bachelor of Science in Nursing, then pass the NCLEX-RN to obtain an active RN license through the Illinois Department of Financial and Professional Regulation. After gaining bedside experience, typically in medical-surgical or infusion settings, you can pursue the Oncology Certified Nurse credential offered by the Oncology Nursing Certification Corporation, which most Illinois employers recognize as the benchmark for oncology practice.
How much do oncology registered nurses make in Illinois?
Oncology registered nurses in Illinois earn a median of about $95,990 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $69,170 for the lowest 10% to over $118,190 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire oncology registered nurses in Illinois?
Companies currently hiring oncology registered nurses in Illinois include Advocate Aurora Health, Northwestern Medicine, and Endeavor Health, per current listings on Migrate Mate as of October 2026. Illinois's dense network of academic medical centers and regional cancer programs means consistent openings across both major metros and mid-sized communities throughout the state.
Which Illinois cities have the most oncology registered nurse jobs?
Chicago, Peoria, and Springfield have the most oncology registered nurse openings in Illinois. Chicago drives the largest share of listings because of its concentration of National Cancer Institute-designated cancer centers and major academic health systems, while suburban and downstate cities with large regional hospitals, such as those anchored by OSF HealthCare and Carle Health, also generate consistent demand.
Are there remote oncology registered nurse jobs in Illinois?
Yes, but they're rare. About 50% of oncology registered nurse openings tied to Illinois are remote or hybrid as of October 2026, reflecting that most oncology nursing work requires direct patient contact for infusion administration, assessment, and care coordination. The portions of the role most adaptable to remote work are telephone triage, patient navigation, and care management positions within larger Illinois health systems.
How can I get hired as a oncology registered nurse in Illinois with little or no experience?
The most realistic entry path is applying to a nurse residency or new-graduate oncology fellowship at a large Illinois academic health system, with programs at institutions such as Northwestern Memorial, University of Chicago Medicine, and Rush University Medical Center designed specifically for RNs without oncology experience. Gaining initial experience in medical-surgical or infusion nursing at an Illinois community hospital also positions candidates well, and completing the ONS chemotherapy certification course early signals commitment to prospective oncology hiring managers.
Where can I find and apply to oncology registered nurse jobs in Illinois?
You can find and apply to oncology registered nurse jobs in Illinois on Migrate Mate, which lists current Illinois openings across health systems, cancer centers, and outpatient infusion practices. Find roles that fit your experience and specialty area and apply directly from the listings.
See All 69 Oncology Registered Nurse Jobs in Illinois
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