Nurse Practitioner Or Physician Assistant Jobs in Illinois
Nurse Practitioner Or Physician Assistant jobs in Illinois represent one of the Midwest's most active advanced practice markets, with demand concentrated in hospital systems, federally qualified health centers, and specialty outpatient practices at levels from new graduate to lead clinician. The largest hiring activity centers on Chicago, Rockford, and Peoria, where systems like Northwestern Medicine, Advocate Health Care, and OSF HealthCare maintain deep and ongoing needs. The most sought-after specialties include primary care, urgent care, and cardiology. Find a role that fits below and apply directly.
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At Northwestern Medicine, every patient interaction makes a difference in cultivating a positive workplace. This patient-first approach is what sets us apart as a leader in the healthcare industry. As an integral part of our team, you'll have the opportunity to join our quest for better health care, no matter where you work within the Northwestern Medicine system. We pride ourselves on providing competitive benefits: from tuition reimbursement and loan forgiveness to 401(k) matching and lifecycle benefits, our goal is to take care of our employees. Ready to join our quest for better?
Job Description
Northwestern Medicine has an exciting opportunity for either a Nurse Practitioner or a Physician Assistant to work in our outpatient Hematology/Oncology Sarcoma department. The APP will see return/active treatment patients, toxicity checks, and post hospitalization follow up visits. This position will be both in clinic with physicians and independent clinic time.
Schedule: M-F, 4x10s (day off TBD)
- no nights/weekends/holidays/on-call
Essential Functions:
- Demonstrates clinical expertise and expanded knowledge through patient care activities which may include diagnosis and management of a wide range of health problems.
- Responsible for health outcome of an assigned patient population.
- Confers with collaborating physician and other health professionals in area of clinical expertise.
- Develops appropriate educational systems for patients, families and staff in areas of expertise.
- Mentors graduate students in aspects of advanced practice and patient care.
- Actively participates in quality improvement and/or research pertinent to area of expertise.
Responsibilities:
- Conducts comprehensive appraisals of patients' health status by taking health histories and performing physical examinations in clinical area.
- Provides direct clinical care to patients.
- Prescribes/orders medications, therapies; orders/interprets laboratory tests, x-rays and procedures according to clinical privileges.
- Evaluates patients to determine their need for further health care.
- Provides comprehensive teaching to patients and families.
- Documents in the medical record all care and education provided and/or procedures performed for which the Licensed Advanced Practice Provider is responsible.
- Refers to other disciplines as appropriate.
- Consultant to other disciplines in areas of expertise.
- Integrates research based knowledge and clinical expertise in decision making.
- Exemplifies a professional image in appearance, manner and presentation.
- Advocate for patients, families, coworkers, and the community.
- Maintains certifications and continuing education as required for licensure and privileging.
- Serves as a patient advocate and role model for "Patients First".
- Participates in unit/departmental/divisional or hospital committees/task forces as appropriate.
- Provides comprehensive teaching strategies for patients and their families.
- Develops and participates in programs to meet continuing education needs of staff.
- Serves as a role model and preceptor to students.
- Provides formal education to both internal and external groups pertinent to area of specialty.
- Participates in quality improvement and/or research initiatives for specific patient population as appropriate.
Qualifications
Required:
- Master’s degree from an accredited school/college of nursing OR master's degree from an accredited Physician Assistant Program
- Current license as a Registered Nurse in the State of Illinois. Current license as an Advanced Practice Registered Nurse in the State of Illinois. Certification as an Advanced Practice Registered Nurse by a national certifying body as approved by the Illinois Department of Regulation APRN Board. Once licensed may apply for a controlled substance license and DEA number OR Master’s degree from an accredited Physician Assistant Program/Current license as a Physician Assistant in the State of Illinois. Once licensed may apply for a controlled substance license and DEA number
- Privileged and credentialed through the Medical Staff Office (MSO)
- Cardio-Pulmonary Resuscitation – BLS, issued by the American Heart Association
- Oncology experience as either a RN or APP is required
Additional Information
Northwestern Medicine is an equal opportunity employer (disability, VETS) and does not discriminate in hiring or employment on the basis of age, sex, race, color, religion, national origin, gender identity, veteran status, disability, sexual orientation or any other protected status.
Background Check
Northwestern Medicine conducts a background check that includes criminal history on newly hired team members and, at times, internal transfers. If you are offered a position with us, you will be required to complete an authorization and disclosure form that gives Northwestern Medicine permission to run the background check. Results are evaluated on a case-by-case basis, and we follow all local, state, and federal laws, including the Illinois Health Care Worker Background Check Act.
Artificial Intelligence Disclosure
Artificial Intelligence (AI) tools may be used in some portions of the candidate review process for this position, however, all employment decisions will be made by a person.
Benefits
We offer a wide range of benefits that provide employees with tools and resources to improve their physical, emotional, and financial well-being while providing protection for unexpected life events. Please visit our Benefits section to learn more.
Sign-on Bonus Eligibility (if sign-on bonus offered for position): Internal employees and rehires who left Northwestern Medicine within 1 year are not eligible for the sign on bonus. Exception: New graduate internal employees seeking their first licensed clinical position at NM may be eligible depending upon the job family.
See All 152+ Nurse Practitioner Or Physician Assistant Jobs in Illinois
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Find JobsNurse Practitioner Or Physician Assistant Jobs by City in Illinois
Where Illinois roles are concentrated, by current openings.
Nurse Practitioner Or Physician Assistant Job Market in Illinois
A snapshot from current Illinois openings, updated as new roles post.
Who's Hiring
- Signify Health37

- Northwestern Medicine15

- Advocate Aurora Health13

- WellNow Urgent Care10

- Springfield Clinic9

Top Industries Hiring
- Healthcare & Medical Services
- Biotechnology & Pharmaceuticals
What Illinois Employers Look For
The qualifications that appear most often in nurse practitioner or physician assistant jobs across Illinois.
- Active Illinois nurse practitioner or physician assistant license issued by IDFPR required
- Master's degree or doctoral degree in nursing or physician assistant studies required
- Board certification from AANP, ANCC, or NCCPA required for all clinical positions
- Current DEA registration and Illinois controlled substance license for prescribing roles
- BLS and ACLS certification required for acute care and hospital-based positions
- Two or more years of clinical experience preferred in specialty or high-volume practice settings
Nurse Practitioner Or Physician Assistant Jobs in Illinois: Frequently Asked Questions
How do you become a nurse practitioner or physician assistant in Illinois?
Nurse practitioners in Illinois must hold an active Advanced Practice Registered Nurse license from the Illinois Department of Financial and Professional Regulation, which requires completing an accredited graduate-level nursing program and passing either the AANP or ANCC board certification exam. Physician assistants must obtain an Illinois PA license through IDFPR after completing an accredited PA program and passing the PANCE. Both roles also require a collaborative agreement or supervision arrangement with a physician under Illinois law.
Which companies hire nurse practitioner or physician assistants in Illinois?
Employers hiring nurse practitioner or physician assistants in Illinois right now include Signify Health, Northwestern Medicine, and Advocate Aurora Health, based on current listings on Migrate Mate as of August 2026. Illinois's large integrated health systems and federally qualified health centers consistently maintain some of the highest open caseloads in the region, particularly in Chicago and its surrounding suburbs.
Which Illinois cities have the most nurse practitioner or physician assistant jobs?
Illinois, Chicago, and Springfield consistently lead Illinois for nurse practitioner or physician assistant openings. Chicago dominates by volume given its concentration of major academic medical centers, specialty groups, and community health networks, while Rockford and Peoria generate steady demand through regional anchor systems like OSF HealthCare and Mercyhealth that serve large surrounding rural populations.
Are there remote nurse practitioner or physician assistant jobs in Illinois?
Yes, but they're rare. Most nurse practitioner and physician assistant work is hands-on and requires an on-site clinical presence, so fully remote positions make up a small fraction of openings. About 58% of nurse practitioner or physician assistant openings tied to Illinois are remote or hybrid as of August 2026. The roles most likely to offer remote components are telehealth urgent care, chronic disease management, and psychiatric or behavioral health services.
How can I get hired as a nurse practitioner or physician assistant in Illinois with little or no experience?
The most realistic entry path is through a nurse practitioner or physician assistant residency or fellowship program, which Northwestern Medicine, University of Illinois Health, and several Federally Qualified Health Centers in the Chicago area offer specifically for new graduates. Candidates without clinical hours in an advanced practice role can also pursue positions in urgent care or retail clinic settings, which tend to hire new graduates with strong rotational backgrounds. Holding a current IDFPR license and specialty board certification from day one significantly strengthens a new-graduate application.
Where can I find and apply to nurse practitioner or physician assistant jobs in Illinois?
You can find and apply to nurse practitioner or physician assistant jobs in Illinois on Migrate Mate, which lists current Illinois openings updated regularly. Find roles that fit your specialty, experience level, and preferred location, then apply directly to each employer through the listing.
See All 152+ Nurse Practitioner Or Physician Assistant Jobs in Illinois
Find roles in Illinois that match your experience and apply in just a few clicks.
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