Nurse Practitioner Or Physician Assistant Jobs in Illinois

Nurse Practitioner Or Physician Assistant jobs in Illinois represent one of the Midwest's most active advanced practice markets, with demand concentrated in hospital systems, federally qualified health centers, and specialty outpatient practices at levels from new graduate to lead clinician. The largest hiring activity centers on Chicago, Rockford, and Peoria, where systems like Northwestern Medicine, Advocate Health Care, and OSF HealthCare maintain deep and ongoing needs. The most sought-after specialties include primary care, urgent care, and cardiology. Find a role that fits below and apply directly.

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Overview

Open roles152+
Top employerSignify Health
Top cityIllinois
Cities hiring59
Work type58% Remote
Top industryHealthcare

Showing 5 of 152+ Nurse Practitioner Or Physician Assistant jobs

Northwestern Medicine
Nurse Practitioner or Physician Assistant-Hematology/Oncology - Sarcoma, Full-time, Days
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Northwestern Medicine
Added 1d ago
Nurse Practitioner or Physician Assistant-Hematology/Oncology - Sarcoma, Full-time, Days
Northwestern Medicine
Chicago, Illinois
Healthcare Administration
Nursing
Patient Services & Wellbeing
$61 - $79.67/hr
BLS Certification
10,000+

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Northwestern Medicine
Acute Care Nurse Practitioner or Physician Assistant - Neurocritical Care, PRN
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Northwestern Medicine
Added 2d ago
Acute Care Nurse Practitioner or Physician Assistant - Neurocritical Care, PRN
Northwestern Medicine
Chicago, Illinois
Clinical Support
Healthcare Administration
Medical Coding & Billing
$63 - $82.28/hr
BLS Certification
10,000+

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S
Nurse Practitioner or Physician Assistant - Dermatology
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S
Added 2d ago
Nurse Practitioner or Physician Assistant - Dermatology
Southern Illinois Dermatology
Harrisburg, Illinois
Healthcare Administration
Nursing
Patient Services & Wellbeing
On-Site
American Board of Dermatology Certification

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Springfield Clinic
Physician Assistant or Nurse Practitioner- Occupational Medicine - Decatur - IPT
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Springfield Clinic
Added 5d ago
Physician Assistant or Nurse Practitioner- Occupational Medicine - Decatur - IPT
Springfield Clinic
Decatur, Illinois
Healthcare Administration
Nursing
Patient Services & Wellbeing
1,001-5,000

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Vituity
Lead Physician Assistant or Nurse Practitioner - Emergency Medicine - OSF HealthCare
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Vituity
Added 5d ago
Lead Physician Assistant or Nurse Practitioner - Emergency Medicine - OSF HealthCare
Vituity
Evergreen Park, Illinois
Healthcare Administration
Patient Services & Wellbeing
Physicians
PALS Certification
1,001-5,000

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See All 152+ Nurse Practitioner Or Physician Assistant Jobs in Illinois

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Nurse Practitioner Or Physician Assistant Jobs by City in Illinois

Where Illinois roles are concentrated, by current openings.

Chicago
20 jobs
Springfield
8 jobs
Marion
4 jobs
Oak Lawn
4 jobs
Bloomingdale
4 jobs
Peoria
3 jobs
Decatur
3 jobs
Rockford
3 jobs
Peru
2 jobs

Nurse Practitioner Or Physician Assistant Job Market in Illinois

A snapshot from current Illinois openings, updated as new roles post.

Who's Hiring

  • Signify Health
    Signify Health37
  • Northwestern Medicine
    Northwestern Medicine15
  • Advocate Aurora Health
    Advocate Aurora Health13
  • WellNow Urgent Care
    WellNow Urgent Care10
  • Springfield Clinic
    Springfield Clinic9

Top Industries Hiring

  • Healthcare & Medical Services
  • Biotechnology & Pharmaceuticals

What Illinois Employers Look For

The qualifications that appear most often in nurse practitioner or physician assistant jobs across Illinois.

  • Active Illinois nurse practitioner or physician assistant license issued by IDFPR required
  • Master's degree or doctoral degree in nursing or physician assistant studies required
  • Board certification from AANP, ANCC, or NCCPA required for all clinical positions
  • Current DEA registration and Illinois controlled substance license for prescribing roles
  • BLS and ACLS certification required for acute care and hospital-based positions
  • Two or more years of clinical experience preferred in specialty or high-volume practice settings

Nurse Practitioner Or Physician Assistant Jobs in Illinois: Frequently Asked Questions

How do you become a nurse practitioner or physician assistant in Illinois?

Nurse practitioners in Illinois must hold an active Advanced Practice Registered Nurse license from the Illinois Department of Financial and Professional Regulation, which requires completing an accredited graduate-level nursing program and passing either the AANP or ANCC board certification exam. Physician assistants must obtain an Illinois PA license through IDFPR after completing an accredited PA program and passing the PANCE. Both roles also require a collaborative agreement or supervision arrangement with a physician under Illinois law.

Which companies hire nurse practitioner or physician assistants in Illinois?

Employers hiring nurse practitioner or physician assistants in Illinois right now include Signify Health, Northwestern Medicine, and Advocate Aurora Health, based on current listings on Migrate Mate as of August 2026. Illinois's large integrated health systems and federally qualified health centers consistently maintain some of the highest open caseloads in the region, particularly in Chicago and its surrounding suburbs.

Which Illinois cities have the most nurse practitioner or physician assistant jobs?

Illinois, Chicago, and Springfield consistently lead Illinois for nurse practitioner or physician assistant openings. Chicago dominates by volume given its concentration of major academic medical centers, specialty groups, and community health networks, while Rockford and Peoria generate steady demand through regional anchor systems like OSF HealthCare and Mercyhealth that serve large surrounding rural populations.

Are there remote nurse practitioner or physician assistant jobs in Illinois?

Yes, but they're rare. Most nurse practitioner and physician assistant work is hands-on and requires an on-site clinical presence, so fully remote positions make up a small fraction of openings. About 58% of nurse practitioner or physician assistant openings tied to Illinois are remote or hybrid as of August 2026. The roles most likely to offer remote components are telehealth urgent care, chronic disease management, and psychiatric or behavioral health services.

How can I get hired as a nurse practitioner or physician assistant in Illinois with little or no experience?

The most realistic entry path is through a nurse practitioner or physician assistant residency or fellowship program, which Northwestern Medicine, University of Illinois Health, and several Federally Qualified Health Centers in the Chicago area offer specifically for new graduates. Candidates without clinical hours in an advanced practice role can also pursue positions in urgent care or retail clinic settings, which tend to hire new graduates with strong rotational backgrounds. Holding a current IDFPR license and specialty board certification from day one significantly strengthens a new-graduate application.

Where can I find and apply to nurse practitioner or physician assistant jobs in Illinois?

You can find and apply to nurse practitioner or physician assistant jobs in Illinois on Migrate Mate, which lists current Illinois openings updated regularly. Find roles that fit your specialty, experience level, and preferred location, then apply directly to each employer through the listing.

See All 152+ Nurse Practitioner Or Physician Assistant Jobs in Illinois

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