Clinical Registered Nurse Jobs in California

Clinical Registered Nurse jobs in California represent one of the most active hiring markets in the country, with sustained demand across major hospital systems, academic medical centers, outpatient clinics, and skilled nursing facilities at every level from new graduate through senior clinical nurse. Los Angeles, the San Francisco Bay Area, and San Diego account for the heaviest concentration of openings, where systems like Cedars-Sinai, Kaiser Permanente, and UCSF Health maintain large clinical workforces. Critical care, med-surg, and emergency nursing are the most consistently in-demand specialties statewide. Find a role that fits below and apply directly.

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Overview

Open roles349+
Top employerUniversity of Southern California
Top cityLos Angeles, CA
Cities hiring94
Work type42% Hybrid
Top industryHealthcare

Showing 5 of 349+ Clinical Registered Nurse jobs

Clinical Nurse (RN), GI Oncology Outpatient Clinic (Surgical Specialty )- 8HR Days 1.0
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New 11h ago
Clinical Nurse (RN), GI Oncology Outpatient Clinic (Surgical Specialty )- 8HR Days 1.0
Stanford Health Care
Palo Alto, California
Healthcare Administration
Nursing
Patient Services & Wellbeing
$96.35 - $111.14/hr
Bachelor of Science
10,000+

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Clinical Nurse (RN), Radiation Oncology - 8HR Days, Limited Relief .001
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New 11h ago
Clinical Nurse (RN), Radiation Oncology - 8HR Days, Limited Relief .001
Stanford Health Care
San Jose, California
Healthcare Administration
Nursing
Patient Services & Wellbeing
$111.35 - $126.14/hr
Bachelor of Science
10,000+

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Clinical Nurse (RN), Oncology Multi-Specialty
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New 11h ago
Clinical Nurse (RN), Oncology Multi-Specialty
Stanford Health Care
Emeryville, California
Healthcare Administration
Nursing
Patient Services & Wellbeing
$96.35 - $111.14/hr
Bachelor of Science
10,000+

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Clinical Nurse (RN) - Neurosurgery (AAU L6) - 0.9 FTE, 12-HR, Night Shift
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New 11h ago
Clinical Nurse (RN) - Neurosurgery (AAU L6) - 0.9 FTE, 12-HR, Night Shift
Stanford Health Care
Palo Alto, California
Healthcare Administration
Nursing
Patient Services & Wellbeing
$96.35 - $111.14/hr
Bachelor of Science
10,000+

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Clinical RN - Sharp Memorial Hospital- Emergency Department - FT - Nights - May be eligible for 5k in relocation assistance
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New 16h ago
Clinical RN - Sharp Memorial Hospital- Emergency Department - FT - Nights - May be eligible for 5k in relocation assistance
Sharp HealthCare
San Diego, California
Clinical Support
Healthcare Administration
Medical Coding & Billing
$64.21 - $93.76/hr
PALS Certification
10,000+

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Clinical Registered Nurse Jobs by City in California

Where California roles are concentrated, by current openings.

Los Angeles
80 jobs
Escondido
20 jobs
Greenbrae
12 jobs
Fresno
11 jobs
Long Beach
8 jobs
Sacramento
8 jobs
Van Nuys
6 jobs

Clinical Registered Nurse Job Market in California

A snapshot from current California openings, updated as new roles post.

Who's Hiring

  • University of Southern California36
  • Keck Medicine of USC30
  • Palomar Health24
  • Sharp HealthCare18
  • Stanford Health Care16

Top Industries Hiring

  • Healthcare & Medical Services18
  • Insurance2
  • Education1
  • Non-Profit & Social Services1

What California Employers Look For

The qualifications that appear most often in clinical registered nurse jobs across California.

  • Active California Registered Nurse license issued by the California Board of Registered Nursing
  • Current BLS certification and ACLS certification for acute or critical care settings
  • Associate degree in nursing at minimum, with bachelor of science in nursing preferred by most California systems
  • Minimum one to two years of clinical bedside experience for non-entry-level positions
  • Demonstrated proficiency with electronic health records systems such as Epic or Cerner
  • Strong communication and interdisciplinary collaboration skills in fast-paced clinical environments

Clinical Registered Nurse Jobs in California: Frequently Asked Questions

How do you become a clinical registered nurse in California?

You become a clinical registered nurse in California by completing an accredited nursing program, either an associate degree in nursing or a bachelor of science in nursing, and then passing the NCLEX-RN exam. Licensure is issued by the California Board of Registered Nursing, which requires a completed application, verified education, and exam results. California does not participate in the Nurse Licensure Compact, so a California-specific license is required to work in the state.

How much do clinical registered nurses make in California?

Clinical registered nurses in California earn a median of about $140,270 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $101,260 for the lowest 10% to over $213,320 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinical registered nurses in California?

Employers hiring clinical registered nurses in California right now include University of Southern California, Keck Medicine of USC, and Palomar Health, based on current listings on Migrate Mate as of October 2026. California's scale and density of large integrated health systems means openings appear consistently across urban and suburban locations throughout the year.

Which California cities have the most clinical registered nurse jobs?

Los Angeles, San Diego, and Escondido have the most clinical registered nurse openings in California. Los Angeles and the Bay Area drive volume through their concentration of large academic medical centers and regional hospital networks, while San Diego's mix of military-affiliated hospitals, research institutions, and community health systems sustains steady demand independent of the major northern and southern metro markets.

Are there remote clinical registered nurse jobs in California?

Yes, but they're rare. Clinical registered nursing is a hands-on bedside role, so most positions require in-person presence. About 60% of clinical registered nurse openings tied to California are remote or hybrid as of October 2026, and those roles tend to concentrate in care management, utilization review, and telephonic triage functions rather than direct patient care.

How can I get hired as a clinical registered nurse in California with little or no experience?

The most realistic entry path is a new graduate residency program, which major California systems including Kaiser Permanente, Dignity Health, and Cedars-Sinai run specifically to bring newly licensed RNs into clinical practice with structured mentorship. Applying to med-surg or telemetry units is the most common starting point, as those floors hire new graduates regularly. Holding a current California Board of Registered Nursing license and a BLS certification before applying strengthens any entry-level candidacy, and prior experience as a certified nursing assistant or patient care technician is a recognized credential that many California hiring managers value.

Where can I find and apply to clinical registered nurse jobs in California?

You can find and apply to clinical registered nurse jobs in California on Migrate Mate, which lists current openings across the state. Find roles that fit your experience level and specialty, and apply directly.

See All 349+ Clinical Registered Nurse Jobs in California

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