Clinical Registered Nurse Jobs in Pennsylvania

Clinical Registered Nurse jobs in Pennsylvania are among the most active in the Mid-Atlantic region, with strong demand across hospital systems, outpatient clinics, long-term care, and specialty practices at every level from new graduate through senior clinical nurse. The heaviest hiring concentrates in Philadelphia, Pittsburgh, and Allentown, where anchor systems like Penn Medicine, UPMC, and Lehigh Valley Health Network maintain large nursing workforces. The most in-demand specialties are critical care, medical-surgical, and oncology nursing. Find a role that fits below and apply directly.

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Overview

Open roles133+
Top employerAllegheny Health Network
Top cityPhiladelphia, PA
Cities hiring54
Work type48% On-site
Top industryHealthcare

Showing 5 of 133+ Clinical Registered Nurse jobs

Clinical Nurse 2- Inpatient - RN FT Days -Med/Surg Ortho - Penn Presbyterian
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New 15h ago
Clinical Nurse 2- Inpatient - RN FT Days -Med/Surg Ortho - Penn Presbyterian
Penn Medicine
Philadelphia, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
10,000+

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Clinical Reimbursement Coordinator, RN
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New 16h ago
Clinical Reimbursement Coordinator, RN
Genesis HealthCare
Lebanon, Pennsylvania
Business Development
Program Management
Project Management
$46 - $49/hr
CPR Certification
10,000+

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RN Community Clinical Educator/MDS Coordinator- Buffalo Valley, FT, Days
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Added 1d ago
RN Community Clinical Educator/MDS Coordinator- Buffalo Valley, FT, Days
Evertrue
Lewisburg, Pennsylvania
Corporate Training
Higher Education
K-12 Teaching
$36.86 - $59.13/hr
CPR Certification
1,001-5,000

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Clinical Nurse 1 (RN) - Residency - Post Surgical Care Unit - Hospital Of University of Pennsylvania
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Added 3d ago
Clinical Nurse 1 (RN) - Residency - Post Surgical Care Unit - Hospital Of University of Pennsylvania
Penn Medicine
Philadelphia, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
10,000+

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Part-Time RN Clinical Instructor/Educator (On-Site)
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Added 3d ago
Part-Time RN Clinical Instructor/Educator (On-Site)
Caregivers America
Clarks Summit, Pennsylvania
Clinical Support
Healthcare Administration
Medical Specialists
$35 - $39/hr
On-Site
1,001-5,000

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Clinical Registered Nurse Jobs by City in Pennsylvania

Where Pennsylvania roles are concentrated, by current openings.

Pittsburgh
18 jobs
Sayre
9 jobs
Wilkes-Barre
7 jobs
Allentown
5 jobs
Erie
3 jobs
Hershey
3 jobs
Harrisburg
3 jobs
State College
3 jobs

Clinical Registered Nurse Job Market in Pennsylvania

A snapshot from current Pennsylvania openings, updated as new roles post.

Who's Hiring

  • Allegheny Health Network16
  • Penn Medicine11
  • The Guthrie Clinic8
  • BAYADA Home Health Care7
  • IQVIA5

Top Industries Hiring

  • Healthcare & Medical Services21
  • Biotechnology & Pharmaceuticals2
  • Education1
  • Agriculture & Farming1

What Pennsylvania Employers Look For

The qualifications that appear most often in clinical registered nurse jobs across Pennsylvania.

  • Active Registered Nurse license issued or recognized by the Pennsylvania State Board of Nursing
  • Associate or Bachelor of Science in Nursing degree from an accredited program
  • Current BLS certification, with ACLS required for critical care and emergency settings
  • Minimum one to two years of clinical bedside experience preferred for most open positions
  • Proficiency with electronic health record systems such as Epic or Cerner
  • Demonstrated ability to manage multiple patients and prioritize care in fast-paced units

Clinical Registered Nurse Jobs in Pennsylvania: Frequently Asked Questions

How do you become a clinical registered nurse in Pennsylvania?

To become a clinical registered nurse in Pennsylvania, you must earn an Associate Degree in Nursing or a Bachelor of Science in Nursing from an accredited program, then pass the NCLEX-RN exam. Licensure is issued by the Pennsylvania State Board of Nursing, which is part of the Bureau of Professional and Occupational Affairs. Pennsylvania also participates in the Nurse Licensure Compact, so nurses licensed in other compact states may practice without applying for a separate Pennsylvania license.

How much do clinical registered nurses make in Pennsylvania?

Clinical registered nurses in Pennsylvania earn a median of about $96,430 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $70,800 for the lowest 10% to over $117,900 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire clinical registered nurses in Pennsylvania?

Employers hiring clinical registered nurses in Pennsylvania right now include Allegheny Health Network, Penn Medicine, and The Guthrie Clinic, based on current listings on Migrate Mate as of October 2026. Pennsylvania's large integrated health systems and academic medical centers generate consistent volume across inpatient, outpatient, and specialty care settings throughout the state.

Which Pennsylvania cities have the most clinical registered nurse jobs?

Philadelphia, Pittsburgh, and Sayre have the most clinical registered nurse openings in Pennsylvania. Philadelphia leads due to its concentration of major academic medical centers and health systems, Pittsburgh follows as home to UPMC's expansive regional network, and mid-sized cities like Allentown and Harrisburg reflect the growing demand from regional hospital systems and outpatient campuses serving Pennsylvania's suburban and rural communities.

Are there remote clinical registered nurse jobs in Pennsylvania?

Yes, but they're rare. Clinical registered nursing is a hands-on, patient-facing role, so the vast majority of positions require on-site work. About 52% of clinical registered nurse openings tied to Pennsylvania are remote or hybrid as of October 2026, and those roles typically involve utilization review, care coordination, or telephone triage rather than direct bedside care.

How can I get hired as a clinical registered nurse in Pennsylvania with little or no experience?

The most realistic entry path is a nurse residency or new-graduate program run by a large Pennsylvania health system. UPMC, Penn Medicine, and Jefferson Health all operate structured residency programs designed for nurses with no prior experience, typically placing new graduates into med-surg or step-down units before specialty rotations. Candidates with clinical hours from nursing school, a current Pennsylvania RN license, and BLS certification are competitive for these roles. Lateral entry from licensed practical nursing or patient care technician positions is another common path into clinical RN roles at Pennsylvania hospitals.

Where can I find and apply to clinical registered nurse jobs in Pennsylvania?

You can find and apply to clinical registered nurse jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings. Find roles that fit your experience and specialty, then apply directly to the employer through the listing.

See All 133+ Clinical Registered Nurse Jobs in Pennsylvania

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