Clinical Registered Nurse Jobs in Philadelphia, PA

Clinical Registered Nurse jobs in Philadelphia are concentrated in University City, Center City, and North Philadelphia, where major academic medical centers, specialty hospitals, and community health systems drive consistent demand across critical care, oncology, and pediatric nursing. Employers actively hiring include Penn Medicine, BAYADA Home Health Care, and KeystoneCare. Scan the live roles below and apply to whichever ones fit.

Find Jobs

Overview

Open roles132+
Top employerPenn Medicine
Work type100% Hybrid
Top credentialBLS Certification
Companies hiring9

Showing 5 of 132+ Clinical Registered Nurse jobs

Visiting Nurse Group, Inc.
Full Time or Per Diem RN Home Care Clinical Field Supervisor
We won't show you this job again
Visiting Nurse Group, Inc.
Added 1d ago
Full Time or Per Diem RN Home Care Clinical Field Supervisor
Visiting Nurse Group, Inc.
Philadelphia, Pennsylvania
Business Operations
Executive Leadership & C-Suite
Project Management
Hybrid
Managed Registered Nurses (RNs)
51-200

Have you applied for this role?

Penn Medicine
Clinical Practice Lead RN IV Advanced Medicine Founders 11 at the Clifton Center
We won't show you this job again
Penn Medicine
Added 5d ago
Clinical Practice Lead RN IV Advanced Medicine Founders 11 at the Clifton Center
Penn Medicine
Philadelphia, Pennsylvania
Clinical Support
Healthcare Administration
Mental & Behavioral Health
BLS Certification
10,000+

Have you applied for this role?

Naven Health, Inc
Clinical Care Transition Educator / Registered Nurse - Per Diem - Philadelphia
We won't show you this job again
Naven Health, Inc
Added 6d ago
Clinical Care Transition Educator / Registered Nurse - Per Diem - Philadelphia
Naven Health, Inc
Philadelphia, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
$38.84 - $64.72/hr
1,001-5,000

Have you applied for this role?

Option Care Health
Clinical Care Transition Educator / Registered Nurse - Per Diem - Philadelphia
We won't show you this job again
Option Care Health
Added 6d ago
Clinical Care Transition Educator / Registered Nurse - Per Diem - Philadelphia
Option Care Health
Philadelphia, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
$38.84 - $64.72/hr
5,001-10,000

Have you applied for this role?

BAYADA Home Health Care
RN Clinical Manager- Home Care
We won't show you this job again
BAYADA Home Health Care
Added 1w ago
RN Clinical Manager- Home Care
BAYADA Home Health Care
Philadelphia, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
Managed Registered Nurses (RNs)
10,000+

Have you applied for this role?

See All 132+ Clinical Registered Nurse Jobs in Philadelphia

Find roles in Philadelphia that match your experience and apply in just a few clicks.

Find Jobs

Clinical Registered Nurse Job Market in Philadelphia

Who's Hiring

  • Penn Medicine
    Penn Medicine73
  • BAYADA Home Health Care
    BAYADA Home Health Care13
  • KeystoneCare
    KeystoneCare7
  • Naven Health
    Naven Health7
  • Option Care Health
    Option Care Health7

Top Industries Hiring

  • Education
  • Healthcare & Medical Services

Clinical Registered Nurse Jobs in Philadelphia: Frequently Asked Questions

How do I get a clinical registered nurse job in Philadelphia?

Philadelphia's strongest hiring comes from its academic medical centers in University City, large health systems anchoring Center City, and community hospitals serving North and West Philadelphia neighborhoods. Candidates with experience in critical care, med-surg, or oncology have the clearest path, but behavioral health and pediatric specialties are also in steady demand. Tailoring your application to a system's specific patient population and unit needs gives you a real edge here.

Which companies hire clinical registered nurses in Philadelphia?

Employers hiring clinical registered nurses in Philadelphia right now include Penn Medicine, BAYADA Home Health Care, and KeystoneCare, based on current listings on Migrate Mate as of September 2026. Philadelphia's market is shaped by a dense concentration of academic health systems, nonprofit community hospitals, and specialty care centers, making it one of the more active clinical nursing markets on the East Coast.

Are there remote clinical registered nurse jobs in Philadelphia?

Yes, but they are uncommon given the hands-on nature of clinical nursing. About 100% of clinical registered nurse openings tied to Philadelphia are remote or hybrid as of September 2026, and those positions tend to involve utilization review, case management, or telephonic triage rather than direct patient care. Philadelphia-based insurers and care management organizations are the most likely employers for those hybrid roles.

How can I get a clinical registered nurse job in Philadelphia with little or no experience?

The most realistic entry path in Philadelphia is through a nurse residency or new-graduate program at one of the city's large academic health systems, which run structured cohorts specifically for RNs with under one year of experience. Med-surg, telemetry, and float pool positions at community hospitals in neighborhoods like Frankford and Roxborough also hire new graduates. Completing clinical rotations at a Philadelphia facility and applying internally before graduation significantly improves your odds.

Which industries hire the most clinical registered nurses in Philadelphia?

Most clinical registered nurse openings in Philadelphia sit in Education and Healthcare & Medical Services, per current listings on Migrate Mate as of September 2026. Philadelphia's role as a regional hub for academic medicine, specialty cancer care, and federally qualified health centers means those sectors generate consistently high nursing volume throughout the year.

See All 132+ Clinical Registered Nurse Jobs in Philadelphia

Find roles in Philadelphia that match your experience and apply in just a few clicks.

Find Jobs