Clinical Registered Nurse Jobs in Philadelphia, PA

Clinical Registered Nurse jobs in Philadelphia are concentrated in University City, Center City, and North Philadelphia, where major academic medical centers, specialty hospitals, and community health systems drive consistent demand across critical care, oncology, and pediatric nursing. Employers actively hiring include Penn Medicine, IQVIA, and Tower Health. Scan the live roles below and apply to whichever ones fit.

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Overview

Open roles123+
Top employerPenn Medicine
Work type33% Remote
Top credentialBLS Certification
Companies hiring8

Showing 5 of 123+ Clinical Registered Nurse jobs

Clinical Nurse 2- Inpatient - RN FT Days -Med/Surg Ortho - Penn Presbyterian
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Added 6d ago
Clinical Nurse 2- Inpatient - RN FT Days -Med/Surg Ortho - Penn Presbyterian
Penn Medicine
Philadelphia, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
10,000+

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Clinical Nurse 1 (RN) - Residency - Post Surgical Care Unit - Hospital Of University of Pennsylvania
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Added 1w ago
Clinical Nurse 1 (RN) - Residency - Post Surgical Care Unit - Hospital Of University of Pennsylvania
Penn Medicine
Philadelphia, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
10,000+

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MedTech Vascular Access RN Clinical Educator– Per Diem - Cleveland, OH Pennsylvania, New Jersey or New York
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Added 1w ago
MedTech Vascular Access RN Clinical Educator– Per Diem - Cleveland, OH Pennsylvania, New Jersey or New York
IQVIA
Philadelphia, Pennsylvania
Biotech & Life Sciences
Clinical Trials
Research & Academia
$36 - $38/hr
Associate's degree
10,000+

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Registered Nurse (RN) Clinical Compliance Auditor- Remote
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Added 1w ago
Registered Nurse (RN) Clinical Compliance Auditor- Remote
Guidehealth
Philadelphia, Pennsylvania
Business Operations
Business Strategy
Revenue Operations & Enablement
$82k - $87k/yr
Remote (US)
Managed care organization experience
201-500

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MedTech Clinical Educator RN
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Added 2w ago
MedTech Clinical Educator RN
IQVIA
Philadelphia, Pennsylvania
Clinical Support
Healthcare Administration
Human Resources
Nursing
Associate's degree
10,000+

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Clinical Registered Nurse Job Market in Philadelphia

Who's Hiring

  • Penn Medicine55
  • IQVIA14
  • Tower Health14
  • BAYADA Home Health Care14
  • Guidehealth7

Top Industries Hiring

  • Education
  • Healthcare & Medical Services

Clinical Registered Nurse Jobs in Philadelphia: Frequently Asked Questions

How do I get a clinical registered nurse job in Philadelphia?

Philadelphia's strongest hiring comes from its academic medical centers in University City, large health systems anchoring Center City, and community hospitals serving North and West Philadelphia neighborhoods. Candidates with experience in critical care, med-surg, or oncology have the clearest path, but behavioral health and pediatric specialties are also in steady demand. Tailoring your application to a system's specific patient population and unit needs gives you a real edge here.

Which companies hire clinical registered nurses in Philadelphia?

Employers hiring clinical registered nurses in Philadelphia right now include Penn Medicine, IQVIA, and Tower Health, based on current listings on Migrate Mate as of November 2026. Philadelphia's market is shaped by a dense concentration of academic health systems, nonprofit community hospitals, and specialty care centers, making it one of the more active clinical nursing markets on the East Coast.

Are there remote clinical registered nurse jobs in Philadelphia?

Yes, but they are uncommon given the hands-on nature of clinical nursing. About 67% of clinical registered nurse openings tied to Philadelphia are remote or hybrid as of November 2026, and those positions tend to involve utilization review, case management, or telephonic triage rather than direct patient care. Philadelphia-based insurers and care management organizations are the most likely employers for those hybrid roles.

How can I get a clinical registered nurse job in Philadelphia with little or no experience?

The most realistic entry path in Philadelphia is through a nurse residency or new-graduate program at one of the city's large academic health systems, which run structured cohorts specifically for RNs with under one year of experience. Med-surg, telemetry, and float pool positions at community hospitals in neighborhoods like Frankford and Roxborough also hire new graduates. Completing clinical rotations at a Philadelphia facility and applying internally before graduation significantly improves your odds.

Which industries hire the most clinical registered nurses in Philadelphia?

Most clinical registered nurse openings in Philadelphia sit in Education and Healthcare & Medical Services, per current listings on Migrate Mate as of November 2026. Philadelphia's role as a regional hub for academic medicine, specialty cancer care, and federally qualified health centers means those sectors generate consistently high nursing volume throughout the year.

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