Oncology Registered Nurse Jobs in Pennsylvania

Oncology Registered Nurse jobs in Pennsylvania are among the most active in the mid-Atlantic region, with consistent demand across major academic medical centers, dedicated cancer institutes, and large regional health systems serving patients from entry-level staff nurse through senior clinical positions. The heaviest hiring concentrates in Philadelphia, Pittsburgh, and the Lehigh Valley, anchored by institutions such as Penn Medicine, UPMC, and Jefferson Health. Infusion nursing, bone marrow transplant care, and oncology patient navigation are the most sought-after specialties across these markets. Find a role that fits below and apply directly.

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Overview

Open roles56
Top employerAllegheny Health Network
Top cityPittsburgh, PA
Cities hiring29
Work type100% On-site
Top industryHealthcare

Showing 4 of 56+ Oncology Registered Nurse jobs

Trinity Health
Registered Nurse - MS1D Oncology - Per Diem Days
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Trinity Health
Added 1d ago
Registered Nurse - MS1D Oncology - Per Diem Days
Trinity Health
Langhorne, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
BLS Certification
10,000+

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Penn Highlands Healthcare
Registered Nurse (RN), Oncology
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Penn Highlands Healthcare
Added 1d ago
Registered Nurse (RN), Oncology
Penn Highlands Healthcare
DuBois, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
CPR Certification
11-50

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Penn Medicine
Triage Registered Nurse RN Oncology Medical Clinic (Full Time/Days)
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Penn Medicine
Added 2d ago
Triage Registered Nurse RN Oncology Medical Clinic (Full Time/Days)
Penn Medicine
Lancaster, Pennsylvania
Healthcare Administration
Nursing
Patient Services & Wellbeing
Bachelor of Science
10,000+

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Geisinger
RN - Registered Nurse - Advanced Acute Care Medical and Oncology Unit
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Geisinger
Added 2d ago
RN - Registered Nurse - Advanced Acute Care Medical and Oncology Unit
Geisinger
Scranton, Pennsylvania
Allied Health
Healthcare Administration
Mental & Behavioral Health
Social Work & Counseling
BLS Certification
10,000+

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Oncology Registered Nurse Jobs by City in Pennsylvania

Where Pennsylvania roles are concentrated, by current openings.

Pittsburgh
8 jobs
Jefferson Hills
7 jobs
Sayre
4 jobs
Philadelphia
4 jobs
York
3 jobs
Scranton
2 jobs
Lancaster
2 jobs
Greensburg
2 jobs
Harrisburg
2 jobs

Oncology Registered Nurse Job Market in Pennsylvania

A snapshot from current Pennsylvania openings, updated as new roles post.

Who's Hiring

  • Allegheny Health Network
    Allegheny Health Network13
  • WellSpan Health
    WellSpan Health7
  • UPMC
    UPMC4
  • Geisinger
    Geisinger4
  • Penn Medicine
    Penn Medicine3

Top Industries Hiring

  • Healthcare & Medical Services20
  • Agriculture & Farming1
  • Biotechnology & Pharmaceuticals1

What Pennsylvania Employers Look For

The qualifications that appear most often in oncology registered nurse jobs across Pennsylvania.

  • Active registered nurse license issued or recognized by the Pennsylvania State Board of Nursing
  • Bachelor of Science in Nursing preferred or required by most Pennsylvania health systems
  • Oncology Certified Nurse credential (OCN) required or expected within a defined timeframe
  • Minimum one to two years of acute care or oncology nursing experience for most clinical roles
  • Current Basic Life Support and Advanced Cardiovascular Life Support certification required
  • Experience with electronic health records platforms such as Epic or Cerner commonly required

Oncology Registered Nurse Jobs in Pennsylvania: Frequently Asked Questions

How do you become a oncology registered nurse in Pennsylvania?

You must first earn an active registered nurse license through the Pennsylvania State Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN. From there, most oncology positions expect at least one year of clinical nursing experience, often in medical-surgical or oncology units. The Oncology Nursing Certification Corporation's OCN credential, while not always required at entry, is a recognized standard that Pennsylvania employers consistently list as preferred for advancement.

How much do oncology registered nurses make in Pennsylvania?

Oncology registered nurses in Pennsylvania earn a median of about $96,430 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $70,800 for the lowest 10% to over $117,900 for the top 10%. Pay rises with experience, specialty, and employer.

Which companies hire oncology registered nurses in Pennsylvania?

Employers hiring oncology registered nurses in Pennsylvania right now include Allegheny Health Network, WellSpan Health, and UPMC, based on current listings on Migrate Mate as of August 2026. Pennsylvania's dense concentration of large academic health systems and National Cancer Institute-designated cancer centers creates consistent, year-round demand for oncology nursing staff across inpatient and outpatient settings.

Which Pennsylvania cities have the most oncology registered nurse jobs?

Pittsburgh, Jefferson Hills, and Sayre account for the largest share of oncology registered nurse openings in Pennsylvania. Philadelphia leads because it is home to major NCI-designated centers including Penn Medicine's Abramson Cancer Center and Jefferson Health, while Pittsburgh's market is anchored by UPMC Hillman Cancer Center, and the Lehigh Valley draws volume from St. Luke's and Lehigh Valley Health Network serving a fast-growing regional population.

Are there remote oncology registered nurse jobs in Pennsylvania?

Yes, but they're rare. Oncology nursing is primarily a hands-on clinical role requiring direct patient contact, so fully remote positions represent only a small share of openings. About 0% of oncology registered nurse openings tied to Pennsylvania are remote or hybrid as of August 2026, and those positions tend to be in telephonic triage, care coordination, or oncology case management rather than bedside or infusion care.

How can I get hired as a oncology registered nurse in Pennsylvania with little or no experience?

The most realistic entry path is a new-graduate residency or nurse residency program, which UPMC, Penn Medicine, and Jefferson Health all offer in Pennsylvania for nurses who have no specialty experience. Gaining initial experience in a medical-surgical or hematology unit builds the foundational skills oncology hiring managers look for. Completing the chemotherapy administration certification through the Oncology Nursing Society and obtaining your OCN eligibility as early as possible signals commitment and gives you a concrete credential edge in a competitive applicant pool.

Where can I find and apply to oncology registered nurse jobs in Pennsylvania?

You can find and apply to oncology registered nurse jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings from employers actively hiring in the state. Search the roles available, find the ones that fit your experience and location, and apply directly to the employer without any additional sign-up steps required.

See All 56 Oncology Registered Nurse Jobs in Pennsylvania

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