Oncology Registered Nurse Jobs in Pennsylvania
Oncology Registered Nurse jobs in Pennsylvania are among the most active in the mid-Atlantic region, with consistent demand across major academic medical centers, dedicated cancer institutes, and large regional health systems serving patients from entry-level staff nurse through senior clinical positions. The heaviest hiring concentrates in Philadelphia, Pittsburgh, and the Lehigh Valley, anchored by institutions such as Penn Medicine, UPMC, and Jefferson Health. Infusion nursing, bone marrow transplant care, and oncology patient navigation are the most sought-after specialties across these markets. Find a role that fits below and apply directly.
Find JobsOverview
Showing 5 of 55+ Oncology Registered Nurse jobs











Penn State Health - Penn State Health Medical Group LLC
Location: US:PA: Lancaster
Work Type: Part Time
FTE: 0.50
Shift: Day
Hours: 7:45a - 4:15p, work Wednesday through Tuesday (no weekends), then one week off and schedule repeats.
Recruiter Contact: Monica Echeverri at mecheverri@pennstatehealth.psu.edu
SUMMARY OF POSITION:
Provides patients medications and fluids via intravenous injection. May prepare and mix solutions for intake, monitors fluid tubes and injection site, and maintains arterial catheters. Monitors medication ingestion for proper dosage and avoids potential drug complications. The Registered Nurse assesses physical, psychosocial, and learning needs of patients and families.
MINIMUM QUALIFICATION(S):
- Currently licensed to practice as a Registered Nurse by state of employment or holds a multistate RN license through the interstate Nurse Licensure Compact
- AHA BLS prior to end of orientation period
PREFERRED QUALIFICATION(S):
- BSN preferred
WHY PENN STATE HEALTH?
Penn State Health offers exceptional opportunities to learn and grow, exposure to a wide patient population, and the ability to provide individualized, innovative, and specialized care to patients in the community.
Penn State Health offers an exceptional benefits package including medical, dental and vision with no waiting period as well as a Total Rewards Program that highlights a few of the many additional offerings below:
- Be Well with Employee Wellness Programs, and Fitness Discounts (University Fitness Center, Peloton).
- Be Balanced with Generous Paid Time Off, Personal Time, and Paid Parental Leave.
- Be Secured with Retirement, Extended Illness Bank, Life Insurance, and Identity Theft Protection.
- Be Rewarded with Competitive Pay, Tuition Reimbursement, and PAWS UP employee recognition program.
- Be Supported by the HR Solution Center, Learning and Organizational Development and Virtual Benefits Orientation, Employee Exclusive Concierge Service for scheduling.
WHY PENN STATE HEALTH MEDICAL GROUP?
#WeAre committed to providing patient- and family-centered care to all patients —and skillfully handle needs at every level of complexity utilizing our shared governance model of care. The Medical Group is constructed of both primary care and multi-specialty offices that are striving to make a difference in each patient’s healthcare routine. Working alongside seasoned professionals, you will be spearheading the mission of Penn State Health to provide the highest quality care to all patients within their local community! Working with us means being part of a team that strives to provide excellent patient care every day, but also one that works together to set and achieve goals, build on the Penn State Health legacy and create new possibilities for the future.
YOU TAKE CARE OF THEM. WE’LL TAKE CARE OF YOU. State-of-the-art equipment, endless learning, and a culture of excellence – that’s Penn State Health. But what makes our healthcare award-winning? That’s all you.
This job posting is a general outline of duties performed and is not to be misconstrued as encompassing all duties performed within the position. Eligibility for shift differential pay based on the terms outlined in company policy or union contract. All individuals (including current employees) selected for a position will undergo a background check appropriate for the position's responsibilities.
Penn State Health is an Equal Opportunity Employer and does not discriminate on the basis of any protected class including disability or veteran status. Penn State Health’s policies and objectives are in direct compliance with all federal and state constitutional provisions, laws, regulations, guidelines, and executive orders that prohibit or outlaw discrimination.
See All 55 Oncology Registered Nurse Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find JobsOncology Registered Nurse Jobs by City in Pennsylvania
Where Pennsylvania roles are concentrated, by current openings.
Oncology Registered Nurse Job Market in Pennsylvania
A snapshot from current Pennsylvania openings, updated as new roles post.
Who's Hiring
- Allegheny Health Network12

- UPMC7

- Penn Medicine4

- Thomas Jefferson University & Jefferson Health4

- Lehigh Valley Health Network3

Top Industries Hiring
- Healthcare & Medical Services
- Agriculture & Farming
- Biotechnology & Pharmaceuticals
What Pennsylvania Employers Look For
The qualifications that appear most often in oncology registered nurse jobs across Pennsylvania.
- Active registered nurse license issued or recognized by the Pennsylvania State Board of Nursing
- Bachelor of Science in Nursing preferred or required by most Pennsylvania health systems
- Oncology Certified Nurse credential (OCN) required or expected within a defined timeframe
- Minimum one to two years of acute care or oncology nursing experience for most clinical roles
- Current Basic Life Support and Advanced Cardiovascular Life Support certification required
- Experience with electronic health records platforms such as Epic or Cerner commonly required
Oncology Registered Nurse Jobs in Pennsylvania: Frequently Asked Questions
How do you become a oncology registered nurse in Pennsylvania?
You must first earn an active registered nurse license through the Pennsylvania State Board of Nursing, which requires completing an accredited nursing program and passing the NCLEX-RN. From there, most oncology positions expect at least one year of clinical nursing experience, often in medical-surgical or oncology units. The Oncology Nursing Certification Corporation's OCN credential, while not always required at entry, is a recognized standard that Pennsylvania employers consistently list as preferred for advancement.
How much do oncology registered nurses make in Pennsylvania?
Oncology registered nurses in Pennsylvania earn a median of about $96,430 a year, based on May 2025 Bureau of Labor Statistics wage data, ranging from around $70,800 for the lowest 10% to over $117,900 for the top 10%. Pay rises with experience, specialty, and employer.
Which companies hire oncology registered nurses in Pennsylvania?
Employers hiring oncology registered nurses in Pennsylvania right now include Allegheny Health Network, UPMC, and Penn Medicine, based on current listings on Migrate Mate as of October 2026. Pennsylvania's dense concentration of large academic health systems and National Cancer Institute-designated cancer centers creates consistent, year-round demand for oncology nursing staff across inpatient and outpatient settings.
Which Pennsylvania cities have the most oncology registered nurse jobs?
Pittsburgh, Jefferson Hills, and Lancaster account for the largest share of oncology registered nurse openings in Pennsylvania. Philadelphia leads because it is home to major NCI-designated centers including Penn Medicine's Abramson Cancer Center and Jefferson Health, while Pittsburgh's market is anchored by UPMC Hillman Cancer Center, and the Lehigh Valley draws volume from St. Luke's and Lehigh Valley Health Network serving a fast-growing regional population.
Are there remote oncology registered nurse jobs in Pennsylvania?
Yes, but they're rare. Oncology nursing is primarily a hands-on clinical role requiring direct patient contact, so fully remote positions represent only a small share of openings. About 25% of oncology registered nurse openings tied to Pennsylvania are remote or hybrid as of October 2026, and those positions tend to be in telephonic triage, care coordination, or oncology case management rather than bedside or infusion care.
How can I get hired as a oncology registered nurse in Pennsylvania with little or no experience?
The most realistic entry path is a new-graduate residency or nurse residency program, which UPMC, Penn Medicine, and Jefferson Health all offer in Pennsylvania for nurses who have no specialty experience. Gaining initial experience in a medical-surgical or hematology unit builds the foundational skills oncology hiring managers look for. Completing the chemotherapy administration certification through the Oncology Nursing Society and obtaining your OCN eligibility as early as possible signals commitment and gives you a concrete credential edge in a competitive applicant pool.
Where can I find and apply to oncology registered nurse jobs in Pennsylvania?
You can find and apply to oncology registered nurse jobs in Pennsylvania on Migrate Mate, which lists current Pennsylvania openings from employers actively hiring in the state. Search the roles available, find the ones that fit your experience and location, and apply directly to the employer without any additional sign-up steps required.
See All 55 Oncology Registered Nurse Jobs in Pennsylvania
Find roles in Pennsylvania that match your experience and apply in just a few clicks.
Find Jobs