Commercial Business Partner Jobs
Commercial Business Partner jobs are open across financial services, technology, healthcare, and consumer goods, covering specializations in finance, HR, and commercial strategy, from analyst-level roles to director and head-of-function positions. Find a role that fits below and apply directly.
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Relay Tx is a clinical-stage biotech preparing for its transition to a commercial company, and we are looking for a Senior Director, HR Business Partner – Commercial to serve as the senior strategic people partner to our Head of Commercial and Commercial leadership team. This is an opportunity to architect and build Relay’s Commercial organization from the ground up — the structures, talent, and leadership capability needed for a successful first launch — while helping Relay stay true to its culture as it grows. Most importantly, you’ll make an impact by helping to bring life-changing medicines to patients who need them the most!
Reporting to the Chief Administrative Officer as a member of the People leadership team, this role leads people partnership across the Commercial organization, including Sales, Marketing, Market Access, Commercial Operations, and related launch functions.
This role is ideal for a seasoned HR leader who has built or scaled a commercial organization in biotech or pharma, brings deep credibility with commercial executives, and is energized by moving fluidly between enterprise strategy, executive advisory, and hands-on execution during a period of rapid growth.
In this role, you will:
Executive Partnership to Commercial Leadership
- Serve as the primary people partner and trusted advisor to the Head of Commercial on organizational strategy, leadership effectiveness, talent, and culture
- Translate commercial strategy and launch plans into an integrated people strategy covering organization design, workforce planning, talent acquisition priorities, capability building, and leadership development
- Coach senior commercial leaders — many of whom will be new to Relay — on leading through rapid growth, building high-performing teams, and integrating into Relay’s culture and ways of working
- Advise on complex and sensitive leadership matters, employee relations, and executive-level decisions with sound judgment, discretion, and a strong understanding of risk
- Partner with People leadership to align the Commercial people strategy with enterprise priorities and with partner functions such as Clinical Development and Medical Affairs
Commercial Organization Build & Launch Readiness
- Lead the people workstream of Relay’s commercial build, including organization design, phased hiring plans, sequencing of leadership hires, and field force sizing and deployment in partnership with Commercial Operations and Finance
- Partner with Talent Acquisition to execute high-volume, time-sensitive hiring waves — senior commercial leaders, field sales and key account teams, and market access roles — with a high bar for quality and fit
- Partner with Total Rewards to design market-competitive compensation structures, sales incentive compensation plans, and job architecture for commercial and field-based roles
- Design onboarding and integration experiences for commercial hires and new leaders, including field-based and remote employees, that build connection to Relay’s science, mission, and culture
- Partner with Legal, Compliance, and People Operations to establish the policies, training, and infrastructure needed to support a multi-state, field-based workforce
Organizational Effectiveness & Talent Strategy
- Build commercial leadership capability through talent reviews, succession planning, and development planning for critical roles
- Establish clear manager expectations and performance practices suited to a commercial environment, including goal setting tied to launch milestones and field performance
- Use people analytics, engagement data, and organizational insights to monitor the health of a fast-growing organization and recommend timely actions
- Anticipate capability needs across the commercial lifecycle — from pre-launch through launch and growth — and shape workforce plans accordingly
Enterprise People Strategy & Leadership
- Contribute to Relay’s enterprise people strategy and operating model as a member of the People leadership team as the company transitions to commercialization
- Shape scalable people programs — performance management, talent reviews and succession, engagement and pulse surveys, and leadership development — that work for research, development, and commercial teams alike
- Partner with colleagues on the People, Finance, IT, and Operations teams as part of a seamless business partner model that supports senior stakeholders
- Bring an external perspective on commercial HR best practices and help build People team capability as the company scales
Change Management & Culture
- Lead change strategies that help the broader organization understand and embrace Relay’s evolution into a commercial company
- Bridge cultures between long-tenured scientific and development teams and newly hired commercial talent, fostering collaboration across functions
- Serve as a culture ambassador, reinforcing Relay’s values and building an inclusive, high-performing environment as the company grows
Critical Competencies
Business-Focused
- Speaks the language of the commercial business — launch planning, field performance, market access — and responds as needs change and the organization scales rapidly
- Aligns the people strategy with broader business and launch priorities
Strategic Thinker
- Sees the possibilities and thinks “yes, if,” rather than “no, because”
- Big-picture thinker who anticipates future trends and consequences and builds people plans ahead of the business
- Challenges the status quo and constantly strives for improvement
Gets it Done
- Take-charge leader who is resourceful, driven, and motivated to achieve
- Comfortable in a fast-paced, dynamic, rapidly growing biotech environment
- A “builder” excited by the journey of standing up and nurturing newly formed teams
- Demonstrates a sense of urgency to overcome obstacles and achieve measurable results
Connector of People
- Communicates clearly, listens, and delivers messages in a “plain language” way
- Builds rapport quickly and establishes trust, respect, and confidence with executives and frontline employees alike
- Superior written, verbal, and presentation skills
- Politically astute, humble, mature, and flexible, with a high level of collaboration and influencing skill
Qualifications & Experience
- 15+ years of progressive Human Resources experience, including significant senior HR Business Partner experience supporting commercial organizations
- Direct experience supporting a biotech or pharmaceutical commercial organization through a product launch; experience building a commercial function from the ground up strongly preferred
- Proven track record as a strategic advisor to C-suite and senior commercial leaders, with the ability to influence organizational decisions
- Deep expertise in organization design, workforce planning, and large-scale hiring for commercial and field-based teams
- Working knowledge of sales incentive compensation, commercial job architecture, and the people practices of field-based, multi-state workforces
- Strong expertise in leadership coaching, talent management, performance management, employee relations, and change management
- Exceptional executive presence and business acumen, with the ability to connect people strategies to commercial outcomes
- Ability to balance enterprise-level strategic thinking with hands-on execution in a fast-paced, evolving environment
Estimated Salary Range: [$193,000 - $275,000].
The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.
#JO1
About Relay Therapeutics
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.
Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you’re excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!
Relay Tx is a clinical-stage biotech preparing for its transition to a commercial company, and we are looking for a Senior Director, HR Business Partner – Commercial to serve as the senior strategic people partner to our Head of Commercial and Commercial leadership team. This is an opportunity to architect and build Relay’s Commercial organization from the ground up — the structures, talent, and leadership capability needed for a successful first launch — while helping Relay stay true to its culture as it grows. Most importantly, you’ll make an impact by helping to bring life-changing medicines to patients who need them the most!
Reporting to the Chief Administrative Officer as a member of the People leadership team, this role leads people partnership across the Commercial organization, including Sales, Marketing, Market Access, Commercial Operations, and related launch functions.
This role is ideal for a seasoned HR leader who has built or scaled a commercial organization in biotech or pharma, brings deep credibility with commercial executives, and is energized by moving fluidly between enterprise strategy, executive advisory, and hands-on execution during a period of rapid growth.
In this role, you will:
Executive Partnership to Commercial Leadership
- Serve as the primary people partner and trusted advisor to the Head of Commercial on organizational strategy, leadership effectiveness, talent, and culture
- Translate commercial strategy and launch plans into an integrated people strategy covering organization design, workforce planning, talent acquisition priorities, capability building, and leadership development
- Coach senior commercial leaders — many of whom will be new to Relay — on leading through rapid growth, building high-performing teams, and integrating into Relay’s culture and ways of working
- Advise on complex and sensitive leadership matters, employee relations, and executive-level decisions with sound judgment, discretion, and a strong understanding of risk
- Partner with People leadership to align the Commercial people strategy with enterprise priorities and with partner functions such as Clinical Development and Medical Affairs
Commercial Organization Build & Launch Readiness
- Lead the people workstream of Relay’s commercial build, including organization design, phased hiring plans, sequencing of leadership hires, and field force sizing and deployment in partnership with Commercial Operations and Finance
- Partner with Talent Acquisition to execute high-volume, time-sensitive hiring waves — senior commercial leaders, field sales and key account teams, and market access roles — with a high bar for quality and fit
- Partner with Total Rewards to design market-competitive compensation structures, sales incentive compensation plans, and job architecture for commercial and field-based roles
- Design onboarding and integration experiences for commercial hires and new leaders, including field-based and remote employees, that build connection to Relay’s science, mission, and culture
- Partner with Legal, Compliance, and People Operations to establish the policies, training, and infrastructure needed to support a multi-state, field-based workforce
Organizational Effectiveness & Talent Strategy
- Build commercial leadership capability through talent reviews, succession planning, and development planning for critical roles
- Establish clear manager expectations and performance practices suited to a commercial environment, including goal setting tied to launch milestones and field performance
- Use people analytics, engagement data, and organizational insights to monitor the health of a fast-growing organization and recommend timely actions
- Anticipate capability needs across the commercial lifecycle — from pre-launch through launch and growth — and shape workforce plans accordingly
Enterprise People Strategy & Leadership
- Contribute to Relay’s enterprise people strategy and operating model as a member of the People leadership team as the company transitions to commercialization
- Shape scalable people programs — performance management, talent reviews and succession, engagement and pulse surveys, and leadership development — that work for research, development, and commercial teams alike
- Partner with colleagues on the People, Finance, IT, and Operations teams as part of a seamless business partner model that supports senior stakeholders
- Bring an external perspective on commercial HR best practices and help build People team capability as the company scales
Change Management & Culture
- Lead change strategies that help the broader organization understand and embrace Relay’s evolution into a commercial company
- Bridge cultures between long-tenured scientific and development teams and newly hired commercial talent, fostering collaboration across functions
- Serve as a culture ambassador, reinforcing Relay’s values and building an inclusive, high-performing environment as the company grows
Critical Competencies
Business-Focused
- Speaks the language of the commercial business — launch planning, field performance, market access — and responds as needs change and the organization scales rapidly
- Aligns the people strategy with broader business and launch priorities
Strategic Thinker
- Sees the possibilities and thinks “yes, if,” rather than “no, because”
- Big-picture thinker who anticipates future trends and consequences and builds people plans ahead of the business
- Challenges the status quo and constantly strives for improvement
Gets it Done
- Take-charge leader who is resourceful, driven, and motivated to achieve
- Comfortable in a fast-paced, dynamic, rapidly growing biotech environment
- A “builder” excited by the journey of standing up and nurturing newly formed teams
- Demonstrates a sense of urgency to overcome obstacles and achieve measurable results
Connector of People
- Communicates clearly, listens, and delivers messages in a “plain language” way
- Builds rapport quickly and establishes trust, respect, and confidence with executives and frontline employees alike
- Superior written, verbal, and presentation skills
- Politically astute, humble, mature, and flexible, with a high level of collaboration and influencing skill
Qualifications & Experience
- 15+ years of progressive Human Resources experience, including significant senior HR Business Partner experience supporting commercial organizations
- Direct experience supporting a biotech or pharmaceutical commercial organization through a product launch; experience building a commercial function from the ground up strongly preferred
- Proven track record as a strategic advisor to C-suite and senior commercial leaders, with the ability to influence organizational decisions
- Deep expertise in organization design, workforce planning, and large-scale hiring for commercial and field-based teams
- Working knowledge of sales incentive compensation, commercial job architecture, and the people practices of field-based, multi-state workforces
- Strong expertise in leadership coaching, talent management, performance management, employee relations, and change management
- Exceptional executive presence and business acumen, with the ability to connect people strategies to commercial outcomes
- Ability to balance enterprise-level strategic thinking with hands-on execution in a fast-paced, evolving environment
Estimated Salary Range: [$193,000 - $275,000].
The range provided above is based on what we believe to be a reasonable estimate for this job at the time of posting. Actual base salary will depend on a number of factors, including but not limited to, a candidate’s education, experience, skills and location.
#JO1
About Relay Therapeutics
Relay Therapeutics is a clinical-stage precision medicines company transforming the drug discovery process with the goal of bringing life-changing therapies to patients. Built on unparalleled insights into protein motion and how this dynamic behavior relates to protein function, we aim to effectively drug protein targets that have previously been intractable, with an initial focus on enhancing small molecule therapeutic discovery in targeted oncology. Our Dynamo platform integrates an array of leading-edge experimental and computational approaches to provide a differentiated understanding of protein structure and motion to drug these targets. We have built a world-class team of leading experts from each of these disciplines, and they are driven by a deep collaboration at every step of our drug discovery process.
Our team is equal parts fearless and relentless, with a shared passion for working collaboratively in intellectually stimulating environments. If you’re excited by the challenge of putting protein motion at the heart of drug discovery and passionate about making a difference in the lives of patients, join us!
Commercial Business Partner Jobs by Experience Level
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Who's Hiring
Top Industries Hiring
- Staffing & Recruiting
What Employers Look For
The qualifications that appear most often in commercial business partner jobs.
- Bachelor's degree in finance, business, economics, or a related field
- Proficiency in financial modeling, forecasting, and variance analysis
- Experience partnering with senior business leaders to drive commercial decisions
- Advanced skills in Excel, PowerPoint, and business intelligence tools such as Power BI or Tableau
- Strong ability to translate complex data into clear recommendations for non-finance stakeholders
- 5 or more years of experience in a finance, commercial, or strategy role
Tips for Your Commercial Business Partner Job Search
Tailor your resume to each function
Commercial business partner roles differ sharply between finance, HR, and commercial strategy. Rewrite your summary and bullet points to match the specific function in each job posting, using the same language the hiring team uses to describe their priorities.
Quantify your influence on decisions
Hiring managers want to see that your analysis changed something. Replace vague claims about supporting leadership with concrete examples: a forecast you built that redirected budget, a pricing model that improved margin, or a workforce plan that reduced attrition.
Apply early to roles that fit
Migrate Mate lists commercial business partner openings from across the United States in one place, so you can find roles that match and apply directly to each listing.
Target postings that name your tools
Many commercial business partner roles are written around specific modeling tools or planning platforms. When a posting names a tool you use daily, apply before you over-optimize your resume. Demonstrated fluency with their actual stack moves you ahead of generalists.
Prepare a business case for the interview
Most commercial business partner interviews include a case or scenario exercise. Practice structuring a commercial recommendation in 10 minutes or less: state the problem, the data you would pull, your analysis approach, and the decision you would recommend to a senior stakeholder.
Negotiate scope, not just compensation
When you receive an offer, ask which business units you will partner with and whether the role has a seat at leadership meetings. The answers reveal whether the position is advisory or truly embedded, and they give you leverage to shape the role before you accept.
Commercial Business Partner Jobs: Frequently Asked Questions
Which companies are hiring the most commercial business partners?
The most active employers for commercial business partners right now are Albemarle, Jobot, and Biogen, and the most openings are in Massachusetts, Virginia, and North Carolina, based on current listings on Migrate Mate as of November 2026. Demand tends to be highest at large consumer, technology, and financial services companies where commercial teams are structured around dedicated business partnering functions.
How many commercial business partner jobs are remote?
About 91% of commercial business partner openings are fully remote or hybrid as of November 2026, reflecting the analytical and advisory nature of much of the work. Finance and commercial strategy sub-roles tend to offer the most remote flexibility, while HR business partner roles more often require on-site presence for people-facing responsibilities.
How do you become a commercial business partner?
Start by building a foundation in financial analysis, commercial planning, or HR through early-career roles in those functions. Progress into positions where you present findings directly to business leaders rather than only preparing reports for others. Develop fluency in business intelligence tools and practice translating data into actionable recommendations. Moving laterally across functions, such as from finance to HR business partnering, also broadens your profile for senior commercial business partner roles.
Can you get hired as a commercial business partner without direct experience?
Yes, candidates from adjacent roles in financial analysis, management consulting, or HR generalist positions move into commercial business partner roles regularly. The key is demonstrating that you have influenced business decisions, not just supported them. Highlight projects where your analysis changed a budget, headcount plan, or go-to-market approach. Roles labeled 'associate business partner' or 'junior commercial analyst' are structured entry points for candidates making this transition.
What does the commercial business partner interview process look like?
The process typically runs three to four stages. An initial screening with a recruiter or HR contact is followed by a competency interview focused on stakeholder influence and analytical thinking. Most employers then include a case study or technical exercise where you model a commercial scenario or present a recommendation. Final rounds usually involve meeting the business leader you would directly support, with questions centered on how you have handled ambiguity and driven decisions under pressure.
Where can I find and apply to commercial business partner jobs?
You can find and apply to commercial business partner jobs on Migrate Mate, which lists current openings from across the United States in one place. Find roles that match your background and apply directly to each listing. Openings are updated regularly across industries including financial services, technology, healthcare, and consumer goods.
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Find roles that match your experience and apply in just a few clicks.
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