Senior Level Commercial Director Jobs

Senior level commercial director jobs put experienced leaders in charge of revenue strategy, market expansion, and the cross-functional teams that execute commercial plans. Hiring concentrates across Biotechnology & Pharmaceuticals, Technology & Software, and Food & Beverage, with 36% of openings remote or hybrid, and employers like Revolution Medicines, Sony Music Entertainment, and Mineralys Therapeutics hiring at this level now.

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Overview

Open roles57
Top stateNew York
Top employerRevolution Medicines
Top cityNew York, NY
Work type64% On-site
Top industryBiotechnology

Showing 5 of 57+ Senior Level Commercial Director jobs

Director, Commercial Sales Performance Management
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Added 2d ago
Director, Commercial Sales Performance Management
KeyBank
Albany, New York
Strategy & Corporate Development
Project & Program Management
Partnerships & Business Development
Compliance & Legal
Customer Success
Business Strategy
Business Development
Compliance & Risk
$128k - $268k/yr
Hybrid
Bachelor's
10,000+

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Director, AI Commercial Product Strategy
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Added 3d ago
Director, AI Commercial Product Strategy
ibex
Washington, Washington DC
Strategy & Corporate Development
Sales
Marketing
Business Strategy
Product Management
Revenue Operations & Enablement
On-Site
Bachelor's

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Senior Director, Commercial Supply Chain
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Added 1w ago
Senior Director, Commercial Supply Chain
Mineralys Therapeutics, Inc.
Remote
Project & Program Management
Manufacturing Operations
Quality Assurance & Testing (QA Testing)
Compliance & Legal
Compliance & Risk
$200k/yr
Remote (US)
Doctorate

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Director - Commercial Tax Services
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Added 1w ago
Director - Commercial Tax Services
Citrin Cooperman Advisors LLC
Manhattan, New York
Finance
Accounting
Consulting & Professional Services
Partnerships & Business Development
Human Resources
Tax
Business Development
$120k - $240k/yr
On-Site
Bachelor's

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Director of Marketing Excellence & Commercial Performance
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Added 2w ago
Director of Marketing Excellence & Commercial Performance
CONMED
Utica, New York
Marketing
Strategy & Corporate Development
Sales
Customer Success
Project & Program Management
Growth Marketing
Business Strategy
Project Management
$151k - $193k/yr
On-Site
Bachelor's
1,001-5,000

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Senior Level Commercial Director Job Market

Who's Hiring

Revolution Medicines4 open roles
Sony Music Entertainment3 open roles
Mineralys Therapeutics3 open roles

Top Industries Hiring

  • Biotechnology & Pharmaceuticals18
  • Technology & Software8
  • Food & Beverage4
  • Music3
  • Science & Research3

Senior Level Commercial Director Jobs: Frequently Asked Questions

How do I get a senior level commercial director job?

Employers at this level look for demonstrated ownership of P&L outcomes, a history of building or scaling commercial functions, and the ability to align sales, marketing, and product around a unified go-to-market strategy. Candidates who can show they have led cross-functional teams through growth or transformation, not just participated in it, consistently stand out. Executive presence and board-level communication skills matter as much as commercial acumen.

Which companies hire senior level commercial directors?

Companies hiring senior level commercial directors right now include Revolution Medicines, Sony Music Entertainment, and Mineralys Therapeutics, based on current listings on Migrate Mate as of November 2026. Hiring at this level tends to come from mid-market and enterprise organizations building out or restructuring their commercial leadership teams.

Are there remote senior level commercial director jobs?

Yes, though most remote openings require availability across multiple time zones given the cross-functional scope of the role. About 36% of senior level commercial director openings are remote or hybrid as of November 2026, reflecting broader flexibility at the director level without fully eliminating in-person expectations for leadership and client-facing responsibilities.

What makes a commercial director role senior level?

Senior level commercial director roles are defined by full ownership of commercial strategy rather than execution within someone else's plan. Responsibilities typically include setting pricing, channel, and market-entry decisions, leading large or matrixed teams, and reporting directly to C-suite stakeholders. Mentoring junior commercial managers and influencing organizational structure are also common expectations at this stage, distinguishing these roles from mid-level positions focused on operational delivery.

Which industries hire the most senior level commercial directors?

Senior Level commercial director roles concentrate in Biotechnology & Pharmaceuticals, Technology & Software, and Food & Beverage, based on current listings on Migrate Mate as of November 2026. These sectors tend to drive demand at this level because they require sophisticated go-to-market leadership to manage complex buyer relationships, competitive positioning, and revenue growth at scale.