Cybersecurity Manager Jobs in San Francisco, CA
Cybersecurity Manager jobs in San Francisco are concentrated in the Financial District, SoMa, and Mission Bay, across fintech, enterprise software, healthcare technology, and federal contractors with Bay Area offices. Employers hiring right now include Airwallex, Anthropic, and OpenAI. Scan the live roles below and apply to whichever ones fit.
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Our Mission
Our mission is to restore cell health and resilience through cell rejuvenation to reverse disease, injury, and the disabilities that can occur throughout life. For more information, see our website at altoslabs.com.
Our Value
Our Single Altos Value: Everyone Owns Achieving Our Inspiring Mission.
Diversity at Altos
Altos Labs has been named one of the Top 3 Biotech Companies and ranked for the second year on the Forbes 2026 Best Startups in America list. At Altos, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining a diverse and inclusive environment.
What You Will Contribute To Altos
The Altos Security team is looking for a highly collaborative Senior Engineer to join our team to help enhance and extend our human focused security program. You will be working directly with scientists, engineers, and IT staff to enable a hyper collaborative environment supporting world class research and development programs. You will build modern, scalable security capabilities that protect sensitive scientific data and AI/ML workloads, improve our readiness to handle security incidents, and strengthen threat detection, response, and data protection across cloud and on-prem environments. This opportunity will give you the chance to build an effective security program that directly impacts the trust and safety of our organization and its stakeholders. Candidates for this role should take pride in balancing risks and benefits of any security control, system or action as well as always looking for opportunities to optimize, automate, reduce and simplify systems.
Responsibilities
- Develop security controls that can enable scientists and researchers while protecting sensitive data (intellectual property, regulated data, experimental datasets)
- Perform threat modeling and risk assessments for applications, infrastructure, AI/ML systems, and lab/OT environments; translate findings into pragmatic controls and roadmaps
- Leverage DevOps principles and Infrastructure as Code techniques to scale security systems and controls
- Build automations and integrations (SOAR) around tools, processes, and systems to facilitate ongoing operations, reduce toil, and improve response times
- Manage Incident Response - prepare playbooks, perform triage, investigation, and remediation; coordinate cross-functional response; conduct forensic analysis; run tabletop exercises and after-action reviews; continuously improve detection and response
- Secure AI solutions from threats to data security, integrity, and misuse; implement model and prompt safety guardrails; evaluate enterprise and third-party AI tools; contribute to AI usage policies and governance
- Act as a security subject matter expert - educating, training, and mentoring others
Who You Are
An ideal candidate would be representing the Altos Cybersecurity team in the San Francisco Bay Area, San Diego, or Cambridge, UK.
Minimum Qualifications
- 7 years of experience in the technology space (at least 5 with a security focus)
- Comfortable collaborating with engineers, scientists, legal/compliance and IT professionals
- Proficient in on-premises and cloud security engineering, including Infrastructure as Code solutions. Skilled in code security, secrets management, vulnerability scanning, and detection engineering.
- Experience performing application and/or infrastructure design reviews to identify areas of improvement as well as recommending appropriate security controls. Ideal candidates would also follow through to ensure their recommendations are implemented.
- Expertise in managing security incidents, conducting detailed analysis of security events, and overseeing sensitive investigations related to cyber activities
- Bachelor’s degree in Computer Science, Cybersecurity, or related field
- Ability to work without supervision, ability to handle competing priorities.
Preferred Qualifications
- Experience working in a compliance oriented environment (healthcare, government, fintech, ISO, SOC, PCI, etc)
- Information security certifications (CISSP, GIAC, etc)
- Experience with AI risk assessment, red teaming of AI/LLM systems, and defenses against prompt injection, data exfiltration, and excessive agency
The salary range for Redwood City, CA:
- Senior Cybersecurity Engineer: $169,700 - $217,500
- Staff Cybersecurity Engineer: $196,800 - $252,300
The salary range for San Diego, CA:
- Senior Cybersecurity Engineer: $141,400 - $181,300
- Staff Cybersecurity Engineer: $169,700 - $217,500
Exact compensation may vary based on skills, experience, and location. For UK applicants, before submitting your application:
- Please click here to read the Altos Labs EU and UK Applicant Privacy Notice (bit.ly/eu_uk_privacy_notice)
- This Privacy Notice is not a contract, express or implied and it does not set terms or conditions of employment.
Equal Opportunity Employment
We value collaboration and scientific excellence. We believe that a culture of belonging are foundational to scientific innovation and inquiry. At Altos Labs, exceptional scientists and industry leaders from around the world work together to advance a shared mission. Our intentional focus is on Belonging, so that all employees know that they are valued for their unique perspectives. We are all accountable for sustaining an inclusive environment. Altos Labs provides equal employment opportunities to all employees and applicants for employment, without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws. Altos prohibits unlawful discrimination and harassment. This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training. Thank you for your interest in Altos Labs where we strive for a culture of scientific excellence, learning, and belonging.
Note: Altos Labs will not ask you to download a messaging app for an interview or outlay your own money to get started as an employee. If this sounds like your interaction with people claiming to be with Altos, it is not legitimate and has nothing to do with Altos. Learn more about a common job scam at https://www.linkedin.com/pulse/how-spot-avoid-online-job-scams-biron-clark/
See All 146+ Cybersecurity Manager Jobs in San Francisco
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Find Cybersecurity Manager JobsCybersecurity Manager Job Market in San Francisco
Who's Hiring
- Airwallex8

- Anthropic7

- OpenAI5

- CRUSOE4

- Notion4

Top Industries Hiring
- Technology & Software81
- Science & Research16
- Banking & Financial Services11
- Fintech7
- Consulting & Professional Services6
Cybersecurity Manager Jobs in San Francisco: Frequently Asked Questions
How do I get a cybersecurity manager job in San Francisco?
Focus your search on the Financial District, SoMa, and Mission Bay, where fintech firms, cloud infrastructure companies, and health tech employers cluster. Experience with cloud security frameworks, zero-trust architecture, and compliance programs like SOC 2 or HIPAA carries real weight here. Candidates who have led security operations at a growth-stage tech company or a regulated financial institution tend to move fastest through local hiring pipelines.
Which companies hire cybersecurity managers in San Francisco?
Companies currently hiring cybersecurity managers in San Francisco include Airwallex, Anthropic, and OpenAI, per current listings on Migrate Mate as of June 2026. San Francisco's employer mix is heavy on fintech platforms, cloud-native software companies, and large financial institutions, alongside biotech firms and federal agency field offices.
Are there remote cybersecurity manager jobs in San Francisco?
Yes, though the role is partially remote at best for positions requiring hands-on security operations oversight or on-site data center access. About 44% of cybersecurity manager openings tied to San Francisco are remote or hybrid as of June 2026, with the most flexibility appearing at cloud-first software companies in SoMa and the Financial District where policy and program management work can be done off-site.
How can I get a cybersecurity manager job in San Francisco with little or no experience?
The most realistic entry path is moving into a cybersecurity manager role from a senior analyst or security engineer position at one of San Francisco's many mid-size fintech or SaaS companies, which promote from within more readily than large banks. Targeting security engineer roles at growth-stage companies in SoMa or Mission Bay, building familiarity with cloud security tools like AWS Security Hub or Azure Defender, and obtaining a CISSP or CISM certification significantly improves your chances locally.
Which industries hire the most cybersecurity managers in San Francisco?
The sectors hiring the most cybersecurity managers in San Francisco are Technology & Software, Science & Research, and Banking & Financial Services, based on current listings on Migrate Mate as of June 2026. San Francisco's concentration of venture-backed technology companies, major retail banks, and digital health platforms creates consistent demand for security leadership across all three sectors.
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